Research Topics
| Kathleen HawkerSummaryAffiliation: Eli Lilly and Company Country: USA Publications
| Collaborators
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Detail Information
Publications
B-cell-targeted treatment for multiple sclerosis: mechanism of action and clinical dataKathleen Hawker
Ohio State University, Columbus, Ohio 43210, USA
Curr Opin Neurol 21:S19-25. 2008..This article describes the mechanism of action behind B-cell-targeted depletion therapies in development and reviews available clinical data...
Rituximab in patients with primary progressive multiple sclerosis: results of a randomized double-blind placebo-controlled multicenter trialKathleen Hawker
Department of Neurology, The Ohio State University Medical Center, Columbus, USA
Ann Neurol 66:460-71. 2009..We evaluated rituximab in adults with primary progressive MS (PPMS) through 96 weeks and safety through 122 weeks...
Progressive multiple sclerosis: characteristics and managementKathleen Hawker
Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285, USA
Neurol Clin 29:423-34. 2011..This article reviews magnetic resonance imaging and clinical data that show that progression may occur early in the course of MS and specific subsets of progressive patients may respond to disease modifying drugs...
Multiple sclerosisKathleen Hawker
Multiple Sclerosis Program, Department of Neurology, University of Texas, Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Room J3.134, Dallas, TX 75390-9036, USA
Prim Care 31:201-26. 2004
Mycophenolate mofetil in multiple sclerosisElliot M Frohman
Department of Neurology, University of Texas, Southwestern Medical Center at Dallas, USA
Clin Neuropharmacol 27:80-3. 2004..To describe experience with the use of mycophenolate mofetil (MMF) in the treatment of multiple sclerosis (MS)...
A one-year prospective, randomized, placebo-controlled, quadruple-blinded, phase II safety pilot trial of combination therapy with interferon beta-1a and mycophenolate mofetil in early relapsing-remitting multiple sclerosis (TIME MS)Gina M Remington
Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, USA
Ther Adv Neurol Disord 3:3-13. 2010..Despite the small sample size, therapeutic trends were observed in favor of combination therapy. An adequately powered controlled trial of MMF in MS appears warranted...
