A M White

..Characteristics of blackouts among college students in the present study are compared to the standard model of blackouts based on reports from alcoholics...

..Mechanisms underlying alcohol-induced memory impairments include disruption of activity in the hippocampus, a brain region that plays a central role in the formation of new autobiographical memories...

..The present study examined patterns of alcohol use beyond the binge threshold...

..In this review, the changes that take place in the brain during the adolescent years are explored. What happens, how these changes can go awry, and how to help keep adolescent brain development on track will he axamined..

..The available research, reviewed in this manuscript, suggests that HIV-specific transfer factors could prove extremely useful, far more useful than vaccines, in preventing and treating HIV infections...

..The study also examined whether feedback regarding the accuracy of their definitions of standard drinks leads students to alter their self-reported levels of consumption...

..These findings add to a slowly growing literature regarding adolescent substance abuse treatment, and may help clinicians identify marijuana-dependent adolescents at greater risk of relapse or noncompliance...

..This information is critical given the widespread reliance on survey data for assessing the correlates and consequences of college drinking...

..The female students who reported blackouts during the 2 weeks before the survey drank far less than male students did during this time period, supporting the use of gender-specific definitions of risky drinking...

..In the present study we examined the impact of repeated ethanol exposure during adolescence and adulthood on subsequent sensitivity to ethanol-induced motor impairments...

..Given the critical role of motor coordination in the ability to operate motor vehicles and the central role of balance and coordination in field sobriety tests, these data could have important implications if extended to human subjects...

..These data strongly suggest that tolerance to the ataxic effects of alcohol can become conditioned to contextual cues present at the time of alcohol administration...

..0 g/kg ethanol, but was occasionally suppressed by 1.5 g/kg ethanol. Results are interpreted in light of recent behavioral and electrophysiological studies examining the effects of ethanol on hippocampal function...

..These results extend previous research showing that acute ethanol administration and lesions to the hippocampal system produce similar effects on learning and memory in rats...

..Evidence suggests that ethanol disrupts activity in the hippocampus by interacting directly with hippocampal neurons and by interacting with critical hippocampal afferents...

..The findings corroborate observations made by other researchers and suggest that the findings of laboratory studies on college drinking do not necessarily extend to real-world settings...

..Studies of this type have yielded valuable information for prevention, education, and public policy efforts related to underage drinking...

..While research on this topic is still in its infancy, the findings clearly suggest that adolescence represents a unique stage of sensitivity to the impact of alcohol on behavior and brain function...

....

..This paper reviews the major dimensions of the empirical research on place-cell activity and the development of computational models to explain various characteristics of place fields...

..These data show that availability of a single nutrient, choline, during a brief period of prenatal development diminishes vulnerability to neurotoxicity in adolescent offspring...

..This developmental sensitivity is analogous to the effects of ethanol, another commonly used recreational drug...

..These data indicate that dietary supplementation with a single nutrient, choline, during a brief, critical period of prenatal development, alters the structure and function of hippocampal pyramidal cells...

..In addition, the possibility that ethanol-induced changes in neuroactive steroid levels contribute to the impact of ethanol on spatial learning and hippocampal function will be explored...

..The perseverative nature of the behavioral deficit could be related to both cognitive dysfunction and the behavioral components of the addiction process...