Research Topics
| Kevin PelphreySummaryAffiliation: Duke University Medical Center Country: USA Publications
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Detail Information
Publications
Anorexia nervosa and autism spectrum disorders: guided investigation of social cognitive endophenotypesNancy L Zucker
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Psychol Bull 133:976-1006. 2007....
Neural basis of eye gaze processing deficits in autismKevin A Pelphrey
Duke UNC Brain Imaging and Analysis Center, Duke University, Durham, NC 27710, USA
Brain 128:1038-48. 2005..We conclude that lack of modulation of the STS region by gaze shifts that convey different intentions contributes to the eye gaze processing deficits associated with autism...
Visual scanning of faces in autismKevin A Pelphrey
Department of Psychology, UNC Neurodevelopmental Disorders Research Center, University of North Carolina at Chapel Hill, NC, USA
J Autism Dev Disord 32:249-61. 2002..Collectively, these results indicate disorganized processing of face stimuli in autistic individuals and suggest a mechanism that may subserve the social information processing deficits that characterize autism spectrum disorders...
Neuroanatomical substrates of social cognition dysfunction in autismKevin Pelphrey
Department of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27710, USA
Ment Retard Dev Disabil Res Rev 10:259-71. 2004..We conclude with a discussion of several potential future directions in the cognitive neuroscience of social deficits in autism...
Perception of dynamic changes in facial affect and identity in autismKevin A Pelphrey
Department of Psychology and Neuroscience, Duke University, 9 Flowers Drive, Durham, North Carolina, 27708 0086, USA
Soc Cogn Affect Neurosci 2:140-9. 2007....
Brain activation evoked by perception of gaze shifts: the influence of contextKevin A Pelphrey
Duke-UNC Brain Imaging and Analysis Center, Duke University Medical Center, 163 Bell Building, Box 3918, Durham, NC 27710, USA
Neuropsychologia 41:156-70. 2003..For 1s shifts, a strong effect of context was observed in which errors evoked a HDR with extended duration. Although this study focused upon STS, similar effects were also observed in the intraparietal sulcus and fusiform gyrus...
Charting the typical and atypical development of the social brainKevin A Pelphrey
Department of Psychology, Baker Hall 342c, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213, USA
Dev Psychopathol 20:1081-102. 2008..Most recently, this research program has incorporated a developmental perspective in beginning to chart the development of the STS region in children with and without autism...
Face processing without awareness in the right fusiform gyrusJames P Morris
Brain Imaging and Analysis Center, Duke University, Durham, NC, USA
Neuropsychologia 45:3087-91. 2007..Other regions activated by consciously perceived unmasked faces were not activated when faces were masked. These data provide strong evidence for an automatic face-processing region in the right FFG...
The posterior superior temporal sulcus is sensitive to the outcome of human and non-human goal-directed actionsSarah Shultz
Department of Psychology, Yale University, PO Box 208205, New Haven, CT 06520, USA
Soc Cogn Affect Neurosci 6:602-11. 2011..Activation in the pSTS did not differentiate between animate and inanimate actions, suggesting that the pSTS is sensitive to the goal-directed actions of both animate and inanimate entities...
Functional imaging of numerical processing in adults and 4-y-old childrenJessica F Cantlon
Department of Psychological and Brain Sciences, Duke University, Durham, North Carolina, USA
PLoS Biol 4:e125. 2006..More broadly, this is also, to our knowledge, the first cognitive fMRI study to test healthy children as young as 4 y, providing new insights into the neurophysiology of human cognitive development...
Occipitotemporal activation evoked by the perception of human bodies is modulated by the presence or absence of the faceJames P Morris
Duke-UNC Brain Imaging and Analysis Center, Duke University, Durham, North Carolina 27710, USA
Neuropsychologia 44:1919-27. 2006..These results provide new information regarding the importance of a visible face in both the relative activation and deactivation of brain structures engaged in social perception...
Neural bases for impaired social cognition in schizophrenia and autism spectrum disordersAmy E Pinkham
The University of North Carolina at Chapel Hill, Department of Psychology, CB 3270, Davie Hall, Chapel Hill, NC 27599, United States
Schizophr Res 99:164-75. 2008..These findings lend support to models hypothesizing well-defined neural substrates of social cognition and suggest a specific neural mechanism that may underlie social cognitive impairments in both autism and paranoid schizophrenia...
The neural development of an abstract concept of numberJessica F Cantlon
Department of Psychology and Neuroscience, Duke University, Durham, NC 27708, USA
J Cogn Neurosci 21:2217-29. 2009....
Development of visuospatial short-term memory in the second half of the 1st yearKevin A Pelphrey
Department of Psychology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 3366, USA
Dev Psychol 40:836-51. 2004..Memory scores did not vary for the visual and manual tasks. Perseveration was greatest for reach responses, increased with challenge, and decreased with age. ((c) 2004 APA, all rights reserved)..
Developmental changes in category-specific brain responses to numbers and letters in a working memory taskMelissa E Libertus
Department of Psychology and Neuroscience, Duke University, Durham, NC 27708, USA
Neuroimage 44:1404-14. 2009..Lastly, behavioral performance on the WM task was predictive of math and language abilities highlighting the connection between WM and other cognitive abilities in development...
Brain activity evoked by the perception of human walking: controlling for meaningful coherent motionKevin A Pelphrey
Duke-UNC Brain Imaging and Analysis Center, Duke University Medical Center, Durham, North Carolina 27710, USA
J Neurosci 23:6819-25. 2003..These voxel-based analyses also revealed regions of motion-related positive activity in other brain regions, including MT or V5, fusiform gyri, right premotor cortex, and the intraparietal sulci...
Polysensory interactions along lateral temporal regions evoked by audiovisual speechTarra M Wright
Brain Imaging and Analysis Center, Duke University Medical Center, Durham, NC 27710, USA
Cereb Cortex 13:1034-43. 2003..These results confirm the polysensory nature of STS region and demonstrate for the first time that polymodal interactions may both potentiate and inhibit activation...
Functional anatomy of biological motion perception in posterior temporal cortex: an FMRI study of eye, mouth and hand movementsKevin A Pelphrey
Duke-UNC Brain Imaging and Analysis Center, Duke University, Durham, NC 27710, USA
Cereb Cortex 15:1866-76. 2005..Hand-evoked activity also extended into the inferior temporal, middle occipital and lingual gyri. This topography may, in part, reflect the role of particular body motions in different functional activities...
Taking an "intentional stance" on eye-gaze shifts: a functional neuroimaging study of social perception in childrenMatthew W Mosconi
Duke-UNC Brain Imaging and Analysis Center, Duke University, Durham, NC 27710, USA
Neuroimage 27:247-52. 2005..We discuss these findings and potential implications for mapping the neurodevelopment of the social cognition and social perception abnormalities characteristic of autism...
Physiology and functioning: Parents' vagal tone, emotion socialization, and children's emotion knowledgeSusan B Perlman
Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA
J Exp Child Psychol 100:308-15. 2008..These findings suggest that parents' physiological regulation may affect the emotional development of their children by influencing their parenting behaviors...
Regional brain activation evoked when approaching a virtual human on a virtual walkJames P Morris
Duke University, Durham, North Carolina 27710, USA
J Cogn Neurosci 17:1744-52. 2005..This result emphasizes the importance of biological motion in inferring the intentions of others...
Grasping the intentions of others: the perceived intentionality of an action influences activity in the superior temporal sulcus during social perceptionKevin A Pelphrey
Brain Imaging and Analysis Center, Duke University, Durham, NC 27710, USA
J Cogn Neurosci 16:1706-16. 2004....
The superior temporal sulcus differentiates communicative and noncommunicative auditory signalsSarah Shultz
Department of Psychology, Yale University, 2 Hillhouse Ave, New Haven, CT 06511, USA
J Cogn Neurosci 24:1224-32. 2012..The implications of these results for understanding the role of the STS in voice processing and in disorders of social communication, such as autism spectrum disorder, are discussed...
Structural and functional magnetic resonance imaging of autismHeather Cody
UNC Neurodevelopmental Disorders Research Center, University of North Carolina, Chapel Hill, NC 27599 3366, USA
Int J Dev Neurosci 20:421-38. 2002..Together, these two methods combine to contribute to a better understanding of the neural basis and brain phenotype of this disorder...
Tactile perception in adults with autism: a multidimensional psychophysical studyCarissa Cascio
Center for Neurodevelopmental Disorders Research, University of North Carolina, Chapel Hill, NC 27599, USA
J Autism Dev Disord 38:127-37. 2008..These findings suggest normal perception along with certain areas of enhanced perception in autism, consistent with previous studies...
When strangers pass: processing of mutual and averted social gaze in the superior temporal sulcusKevin A Pelphrey
Duke-UNC Brain Imaging and Analysis Center, Duke University Medical Center, Durham, NC 27710, USA
Psychol Sci 15:598-603. 2004..This study extends understanding of the role of the STS in social cognition and social perception by demonstrating that it is highly sensitive to the context in which a human action occurs...
Faces evoke spatially differentiated patterns of BOLD activation and deactivationKevin A Pelphrey
Duke-UNC Brain Imaging and Analysis Center, Duke University Medical Center, 163 Bell Building, Box 3918, Durham, NC 27710, USA
Neuroreport 14:955-9. 2003..These deactivated regions, identified by a decrease in BOLD signal, may reflect populations of neurons that decrease their activity when faces appear, possibly as a consequence of category-specific inhibition...
The influence of prior knowledge and repeated questioning on children's long-term retention of the details of a pediatric examinationPeter A Ornstein
Department of Psychology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 3270, USA
Dev Psychol 42:332-44. 2006..Although knowledge increased with age as expected, it nonetheless affected recall over and above the influence of age...
Perceived causality influences brain activity evoked by biological motionJames P Morris
Duke University, Durham, North Carolina, USA
Soc Neurosci 3:16-25. 2008..Our results demonstrate a strong hemispheric bias in the role of the pSTS in the perception of causality of biological motion...
Working memory in infancyKevin A Pelphrey
Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
Adv Child Dev Behav 31:173-227. 2003
