T Gan

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. ncbi A randomized comparison of a multimodal management strategy versus combination antiemetics for the prevention of postoperative nausea and vomiting
    Ashraf S Habib
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesth Analg 99:77-81. 2004
  2. ncbi Double-blind, randomized comparison of ondansetron and intraoperative propofol to prevent postoperative nausea and vomiting
    T J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesthesiology 85:1036-42. 1996
  3. ncbi Society for Ambulatory Anesthesia guidelines for the management of postoperative nausea and vomiting
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesth Analg 105:1615-28, table of contents. 2007
  4. ncbi Patient-controlled analgesia: patient and nurse satisfaction with intravenous delivery systems and expected satisfaction with transdermal delivery systems
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Curr Med Res Opin 23:2507-16. 2007
  5. ncbi Adenosine as a non-opioid analgesic in the perioperative setting
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Anesth Analg 105:487-94. 2007
  6. ncbi A randomized, double-blind comparison of the NK1 antagonist, aprepitant, versus ondansetron for the prevention of postoperative nausea and vomiting
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Centre, Durham, North Carolina 27710, USA
    Anesth Analg 104:1082-9, tables of contents. 2007
  7. ncbi Pharmacokinetic and pharmacodynamic characteristics of medications used for moderate sedation
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Clin Pharmacokinet 45:855-69. 2006
  8. ncbi Risk factors for postoperative nausea and vomiting
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Anesth Analg 102:1884-98. 2006
  9. ncbi Consensus guidelines for managing postoperative nausea and vomiting
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesth Analg 97:62-71, table of contents. 2003
  10. ncbi Selective serotonin 5-HT3 receptor antagonists for postoperative nausea and vomiting: are they all the same?
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    CNS Drugs 19:225-38. 2005

Detail Information

Publications84

  1. ncbi A randomized comparison of a multimodal management strategy versus combination antiemetics for the prevention of postoperative nausea and vomiting
    Ashraf S Habib
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesth Analg 99:77-81. 2004
    ....
  2. ncbi Double-blind, randomized comparison of ondansetron and intraoperative propofol to prevent postoperative nausea and vomiting
    T J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesthesiology 85:1036-42. 1996
    ..To date no comparison of these two drugs has been reported. A randomized study was done to compare the efficacy of ondansetron and intraoperative propofol given in various regimens...
  3. ncbi Society for Ambulatory Anesthesia guidelines for the management of postoperative nausea and vomiting
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesth Analg 105:1615-28, table of contents. 2007
    ....
  4. ncbi Patient-controlled analgesia: patient and nurse satisfaction with intravenous delivery systems and expected satisfaction with transdermal delivery systems
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Curr Med Res Opin 23:2507-16. 2007
    ..To compare patient and nurse satisfaction with intravenous patient-controlled analgesia (IV-PCA) to their prospective satisfaction with patient-controlled transdermal delivery system (PCTS) technology...
  5. ncbi Adenosine as a non-opioid analgesic in the perioperative setting
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Anesth Analg 105:487-94. 2007
    ..These effects are generally well tolerated and transient. Further studies are warranted to investigate the full potential of adenosine as a non-opioid analgesic in the perioperative setting...
  6. ncbi A randomized, double-blind comparison of the NK1 antagonist, aprepitant, versus ondansetron for the prevention of postoperative nausea and vomiting
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Centre, Durham, North Carolina 27710, USA
    Anesth Analg 104:1082-9, tables of contents. 2007
    ..This is the first study evaluating the efficacy and tolerability of the neurokinin-1 receptor antagonist, aprepitant, for the prevention of postoperative nausea and vomiting...
  7. ncbi Pharmacokinetic and pharmacodynamic characteristics of medications used for moderate sedation
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Clin Pharmacokinet 45:855-69. 2006
    ..Advances in the delivery of sedation, including the development of new sedative agents, have the potential to further improve the provision of moderate sedation for a variety of invasive procedures...
  8. ncbi Risk factors for postoperative nausea and vomiting
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Anesth Analg 102:1884-98. 2006
    ..Further research examining genetic and under-investigated clinical patient characteristics as potential risk factors, and involving outpatients and children, should improve predictive systems...
  9. ncbi Consensus guidelines for managing postoperative nausea and vomiting
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesth Analg 97:62-71, table of contents. 2003
    ..IMPLICATIONS: We present evidence-based guidelines developed by an international panel of experts for the management of postoperative nausea and vomiting...
  10. ncbi Selective serotonin 5-HT3 receptor antagonists for postoperative nausea and vomiting: are they all the same?
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    CNS Drugs 19:225-38. 2005
    ..This review discusses the pharmacological profiles of dolasetron, granisetron, ondansetron and tropisetron, and the clinical implications of differences in their profiles...
  11. ncbi A randomized controlled comparison of electro-acupoint stimulation or ondansetron versus placebo for the prevention of postoperative nausea and vomiting
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Anesth Analg 99:1070-5, table of contents. 2004
    ..Stimulation at P6 also has analgesic effects...
  12. ncbi Patient preferences for acute pain treatment
    T J Gan
    Department of Anesthesiology, Duke University Medical Center, Box 3094, Durham, NC 27710, USA
    Br J Anaesth 92:681-8. 2004
    ..The objective was to investigate the degree to which patients are willing to make these trade-offs...
  13. ncbi A randomized, double-blind study of granisetron plus dexamethasone versus ondansetron plus dexamethasone to prevent postoperative nausea and vomiting in patients undergoing abdominal hysterectomy
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA
    Anesth Analg 101:1323-9. 2005
    ..The combination of small-dose G administered just before tracheal extubation plus D given at induction of anesthesia is an effective alternative to O+D in preventing vomiting during the 0- to 2-h interval after tracheal extubation...
  14. ncbi Goal-directed intraoperative fluid administration reduces length of hospital stay after major surgery
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesthesiology 97:820-6. 2002
    ..The objective of this prospective, randomized study was to assess the effect of goal-directed intraoperative fluid administration on length of postoperative hospital stay...
  15. ncbi Preoperative parenteral parecoxib and follow-up oral valdecoxib reduce length of stay and improve quality of patient recovery after laparoscopic cholecystectomy surgery
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Anesth Analg 98:1665-73, table of contents. 2004
    ....
  16. ncbi Determination of plasma concentrations of propofol associated with 50% reduction in postoperative nausea
    T J Gan
    Duke University Medical Center, Department of Anesthesiology, Durham, North Carolina 27710, USA
    Anesthesiology 87:779-84. 1997
    ..Subhypnotic doses of propofol possess direct antiemetic properties. The authors sought to determine the plasma concentration of propofol needed to effectively manage postoperative nausea and vomiting...
  17. ncbi Bispectral index monitoring allows faster emergence and improved recovery from propofol, alfentanil, and nitrous oxide anesthesia. BIS Utility Study Group
    T J Gan
    Department of Anesthesiology, Duke University, Durham, North Carolina 27710, USA
    Anesthesiology 87:808-15. 1997
    ..This study determined whether addition of BIS monitoring to standard anesthetic practice results in improvements in the conduct of anesthesia or in patient outcomes...
  18. ncbi Opioid-sparing effects of a low-dose infusion of naloxone in patient-administered morphine sulfate
    T J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesthesiology 87:1075-81. 1997
    ..The authors compared the incidence of morphine-related side effects and the quality of analgesia from two small doses of naloxone infusion...
  19. ncbi Women emerge from general anesthesia with propofol/alfentanil/nitrous oxide faster than men
    T J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesthesiology 90:1283-7. 1999
    ..Recovery from general anesthesia is governed by pharmacodynamic and pharmacokinetic factors. Gender has not previously been recognized as a factor influencing the time to emergence from general anesthesia...
  20. ncbi Hextend, a physiologically balanced plasma expander for large volume use in major surgery: a randomized phase III clinical trial. Hextend Study Group
    T J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesth Analg 88:992-8. 1999
    ..It is as effective as 6% hetastarch in saline for the treatment of hypovolemia but has a more favorable side effects profile in volumes of up to 5 L compared with 6% hetastarch in saline...
  21. ncbi Patient-controlled antiemesis: a randomized, double-blind comparison of two doses of propofol versus placebo
    T J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesthesiology 90:1564-70. 1999
    ..The role of propofol for the management of postoperative nausea and vomiting (PONV) is not well established. This study determines the efficacy of small doses of propofol administered by patient-controlled device for the treatment of PONV...
  22. ncbi How much are patients willing to pay to avoid postoperative nausea and vomiting?
    T Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Anesth Analg 92:393-400. 2001
    ..Patients associated a value with the avoidance of PONV and were willing to pay between US$56 and US$100 for a completely effective antiemetic...
  23. ncbi Duration of action of vecuronium after an intubating dose of rapacuronium, vecuronium, or succinylcholine
    T J Gan
    Department of Anesthesiology, Duke University Medical Center, Box 3094, Durham, NC 27710, USA
    Anesth Analg 92:1199-202. 2001
    ..IMPLICATIONS: The duration of action of a maintenance dose of vecuronium was longer after an endotracheal intubating dose of rapacuronium compared with succinylcholine...
  24. ncbi Safety evaluation of fospropofol for sedation during minor surgical procedures
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Anesth 22:260-7. 2010
    ..To evaluate the safety of intravenous (IV) fospropofol when used to provide minimal to moderate sedation in patients undergoing minor surgical procedures...
  25. ncbi Postoperative nausea and vomiting--can it be eliminated?
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Box 3094, Durham, NC 27710, USA
    JAMA 287:1233-6. 2002
  26. ncbi Diclofenac: an update on its mechanism of action and safety profile
    Tong J Gan
    Duke University Medical Center, Durham, North Carolina 27710, USA
    Curr Med Res Opin 26:1715-31. 2010
    ..However, extensive research shows the pharmacologic activity of diclofenac goes beyond COX inhibition, and includes multimodal and, in some instances, novel mechanisms of action (MOA)...
  27. ncbi Ondansetron orally disintegrating tablet versus placebo for the prevention of postdischarge nausea and vomiting after ambulatory surgery
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesth Analg 94:1199-200, table of contents. 2002
    ..IMPLICATIONS: Ondansetron orally disintegrating tablet reduces postdischarge nausea and vomiting and improves patient satisfaction with postoperative nausea and vomiting management...
  28. ncbi A randomized, double-blind, multicenter trial comparing transdermal scopolamine plus ondansetron to ondansetron alone for the prevention of postoperative nausea and vomiting in the outpatient setting
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Anesth Analg 108:1498-504. 2009
    ..We sought to determine whether the use of transdermal scopolamine (TDS) in combination with IV ondansetron (OND) is more effective than one alone for reducing PONV in outpatient settings...
  29. ncbi The dose-response of nitrous oxide in postoperative nausea in patients undergoing gynecologic laparoscopic surgery: a preliminary study
    Boris Mraovic
    Department of Anesthesiology, Thomas Jefferson University, 111 South 11th St Suite G8490, Philadelphia, PA 19107, USA
    Anesth Analg 107:818-23. 2008
    ..We investigated whether N(2)O results in a dose-response increase in PONV...
  30. ncbi The effectiveness of rescue antiemetics after failure of prophylaxis with ondansetron or droperidol: a preliminary report
    Ashraf S Habib
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Anesth 17:62-5. 2005
    ..In patients who failed prophylaxis with droperidol, dimenhydrinate was also more effective than droperidol for the treatment of established PONV in the postoperative anesthesia care unit...
  31. ncbi Comparison of the morphine-sparing effects of diclofenac sodium and ketorolac tromethamine after major orthopedic surgery
    Ratan Alexander
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Anesth 14:187-92. 2002
    ..01. CONCLUSIONS: Preoperative administration of intravenous diclofenac 75 mg or ketorolac 60 mg significantly reduces morphine requirements and associated side effects after major orthopedic surgery...
  32. ncbi The efficacy of the 5-HT3 receptor antagonists combined with droperidol for PONV prophylaxis is similar to their combination with dexamethasone. A meta-analysis of randomized controlled trials
    Ashraf S Habib
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina, USA
    Can J Anaesth 51:311-9. 2004
    ....
  33. ncbi Radical perineal prostatectomy for treatment of localized prostate cancer in obese and nonobese patients: a matched control study
    Benjamin K Yang
    Division of Urologic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Urology 67:990-5. 2006
    ..Specifically, efforts should be directed toward preventing the development of lower extremity neurapraxia by minimizing the operative time and optimizing patient positioning...
  34. ncbi A retrospective comparison of anesthetic management of robot-assisted laparoscopic radical prostatectomy versus radical retropubic prostatectomy
    Richard C D'Alonzo
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Anesth 21:322-8. 2009
    ..To compare anesthetic management and postoperative outcomes in patients undergoing robot-assisted laparoscopic radical prostatectomy (RALP) and radical retropubic prostatectomy (RRP) with general anesthesia...
  35. ncbi How much are patients willing to pay to avoid intraoperative awareness?
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Anesth 15:108-12. 2003
    ..To determine how much patients are willing to pay to avoid intraoperative awareness?..
  36. ncbi Hepatic parenchymal transection with vascular staplers: a comparative analysis with the crush-clamp technique
    Srinevas K Reddy
    Department of Surgery, Duke University Medical Center, Durham, NC, USA
    Am J Surg 196:760-7. 2008
    ..This retrospective study compares the safety and efficacy of hepatic parenchymal transection using vascular staplers (VS) and the crush-clamp (CC) technique...
  37. ncbi The kaolin-activated Thrombelastograph predicts bleeding after cardiac surgery
    Ian J Welsby
    Department of Anesthesiology, Division of Cardiothoracic Anesthesia and Critical Care Medicine, Duke University Medical Center, Durham, NC 27710, USA
    J Cardiothorac Vasc Anesth 20:531-5. 2006
    ....
  38. ncbi The use of droperidol before and after the Food and Drug Administration black box warning: a survey of the members of the Society of Ambulatory Anesthesia
    Ashraf S Habib
    Department of Anesthesiology, Box 3094, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Anesth 20:35-9. 2008
    ..To determine the practice of members of the Society of Ambulatory Anesthesia (SAMBA) in the management of postoperative nausea and vomiting (PONV) before and after the Food and Drug Administration (FDA) black box warning on droperidol...
  39. ncbi Use of neostigmine in the management of acute postoperative pain and labour pain: a review
    Ashraf S Habib
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    CNS Drugs 20:821-39. 2006
    ..Further studies are required to determine the place of the administration of neostigmine by these routes...
  40. ncbi Rolapitant for the prevention of postoperative nausea and vomiting: a prospective, double-blinded, placebo-controlled randomized trial
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, CB 3094, Durham, NC 27710, USA
    Anesth Analg 112:804-12. 2011
    ..We evaluated the dose response for rolapitant for the prevention of PONV in subjects at high risk for this condition, and rolapitant's effects on preventing delayed PONV were explored up to 5 days after surgery...
  41. ncbi A single-institution comparison between radical perineal and radical retropubic prostatectomy on perioperative and pathological outcomes for obese men: an analysis of the Duke Prostate Center database
    Nicholas J Fitzsimons
    Division of Urologic Surgery, Duke University School of Medicine, Durham, North Carolina 27710, USA
    Urology 70:1146-51. 2007
    ....
  42. ncbi A comparison of ondansetron with promethazine for treating postoperative nausea and vomiting in patients who received prophylaxis with ondansetron: a retrospective database analysis
    Ashraf S Habib
    Department of Anesthesiology, Duke University Medical Center, Durham, NC, 27710, USA
    Anesth Analg 104:548-51. 2007
    ..There are little data on the efficacy of antiemetics for treating postoperative nausea and vomiting (PONV) in patients who received prior PONV prophylaxis...
  43. ncbi Postoperative nausea and vomiting in children and adolescents undergoing radiofrequency catheter ablation: a randomized comparison of propofol- and isoflurane-based anesthetics
    Thomas O Erb
    Department of Anesthesiology, Duke University, Durham, North Carolina, USA
    Anesth Analg 95:1577-81, table of contents. 2002
    ....
  44. ncbi Optimising postoperative pain management in the ambulatory patient
    Allan B Shang
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Drugs 63:855-67. 2003
    ..Patient education, early diagnosis of symptoms and aggressive treatment of pain using an integrative approach, combining pharmacotherapy as well as complementary technique, should serve us well in dealing with this complex problem...
  45. ncbi Open radical retropubic prostatectomy 2007: the true minimally invasive surgery for localized prostate cancer?
    Israel P Nosnik
    Duke University School of Medicine, Division of Urology, Box 3707, Durham, NC 27710, USA
    Expert Rev Anticancer Ther 7:1309-17. 2007
    ..The concepts we have articulated here are related to resection and avoidance of positive margins, limited intraoperative blood loss and pain control, which allow equivalence in these outcome areas, regardless of technique...
  46. ncbi Intraoperative colloid administration reduces postoperative nausea and vomiting and improves postoperative outcomes compared with crystalloid administration
    Eugene W Moretti
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesth Analg 96:611-7, table of contents. 2003
    ..We concluded that intraoperative fluid resuscitation with colloid, when compared with crystalloid administration, is associated with an improvement in the quality of postoperative recovery...
  47. ncbi Mechanisms underlying postoperative nausea and vomiting and neurotransmitter receptor antagonist-based pharmacotherapy
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    CNS Drugs 21:813-33. 2007
    ..A successful PONV management strategy includes: (i) identifying patients at risk; (ii) keeping the baseline risk low; and (iii) using a combination of antiemetics acting on different receptors in moderate- to high-risk patients...
  48. ncbi Transdermal nicotine for analgesia after radical retropubic prostatectomy
    Ashraf S Habib
    Department of Anesthesiology, Duke University Medical System, Box 3094, Durham, North Carolina, USA
    Anesth Analg 107:999-1004. 2008
    ..We hypothesized that the preoperative application of a 7 mg nicotine patch would result in reduced postoperative analgesic requirements in patients undergoing radical retropubic prostatectomy (RRP) under general anesthesia...
  49. ncbi Double-blind comparison of granisetron, promethazine, or a combination of both for the prevention of postoperative nausea and vomiting in females undergoing outpatient laparoscopies
    Tong J Gan
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Can J Anaesth 56:829-36. 2009
    ..Although promethazine is effective, commonly used doses are associated with sedation. This study investigates the combination of low doses of granisetron and promethazine for the prevention of PONV...
  50. ncbi Lidocaine patch for postoperative analgesia after radical retropubic prostatectomy
    Ashraf S Habib
    Department of Anesthesiology, Duke University Medical System, Box 3094, Durham, NC 27710, USA
    Anesth Analg 108:1950-3. 2009
    ..0001, time x treatment P = 0.3056) and at rest (17%-32% reduction) for up to 6 h (treatment vs placebo P = 0.0003, time x treatment P = 0.0130)...
  51. ncbi Comparison of postoperative pain outcomes after vertical or Pfannenstiel incision for major gynecologic surgery
    Ashraf S Habib
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Curr Med Res Opin 25:1529-34. 2009
    ....
  52. ncbi Radical perineal prostatectomy for the treatment of localized prostate cancer in morbidly obese patients
    Philipp Dahm
    Departments of Surgery Division of Urologic Surgery, Duke University Medical Center, Durham, North Carolina, USA
    J Urol 174:131-4. 2005
    ..We assessed the feasibility of radical perineal prostatectomy (RPP) in morbidly obese patients with clinically organ confined prostate cancer...
  53. ncbi Absence of adverse outcomes in hyperkalemic patients undergoing vascular access surgery
    Ronald P Olson
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Can J Anaesth 50:553-7. 2003
    ..This study sought to identify and characterize cases where surgery had been performed in patients with uncorrected hyperkalemia...
  54. ncbi Transcutaneous acupoint electrical stimulation with the ReliefBand for the prevention of nausea and vomiting during and after cesarean delivery under spinal anesthesia
    Ashraf S Habib
    Department of Anesthesiology, Box 3094, Duke University Medical Center, Durham, NC, 27710
    Anesth Analg 102:581-4. 2006
    ..There was also no difference between the two groups in nausea scores, number of vomiting episodes, or patient satisfaction with postoperative nausea and vomiting management...
  55. ncbi A study of anesthetic drug utilization in different age groups
    Gavin Martin
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    J Clin Anesth 15:194-200. 2003
    ..To determine anesthetic drug utilization in different age groups...
  56. ncbi Phase 2, double-blind, placebo-controlled, dose-response trial of intravenous adenosine for perioperative analgesia
    Ashraf S Habib
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Anesthesiology 109:1085-91. 2008
    ..The primary aim of this multicenter study was to determine the dose-response profile of adenosine with respect to perioperative analgesia...
  57. ncbi How much are patients willing to pay to avoid postoperative muscle pain associated with succinylcholine?
    Terrence K Allen
    Department of Anesthesiology, Duke University Medical Center, Box 3094, Durham, NC 27710, USA
    J Clin Anesth 19:601-8. 2007
    ..To determine how much money patients are willing to pay to avoid postoperative muscle pains associated with succinylcholine...
  58. ncbi Goal-directed fluid management with trans-oesophageal Doppler
    Anthony M Roche
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Best Pract Res Clin Anaesthesiol 23:327-34. 2009
    ....
  59. ncbi A randomized, double-blind comparison of ondansetron versus placebo for prevention of nausea and vomiting after infratentorial craniotomy
    Jennifer M Fabling
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina, USA
    J Neurosurg Anesthesiol 14:102-7. 2002
    ..Scheduled prophylactic administration of antiemetic therapy during the first 48 hours after infratentorial craniotomy should be evaluated for efficacy and safety...
  60. ncbi Comparison of electrophysiologic effects of propofol and isoflurane-based anesthetics in children undergoing radiofrequency catheter ablation for supraventricular tachycardia
    Thomas O Erb
    Department of Anesthesiology, Duke University, Durham, North Carolina, USA
    Anesthesiology 96:1386-94. 2002
    ..It remains unclear whether the ability to successfully perform RFCA differs between these drugs...
  61. ncbi Pharmacology, pharmacogenetics, and clinical efficacy of 5-hydroxytryptamine type 3 receptor antagonists for postoperative nausea and vomiting
    Kok-Yuen Ho
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Curr Opin Anaesthesiol 19:606-11. 2006
    ..Given the multifactorial nature of postoperative nausea and vomiting, a multimodal approach to reduce or eliminate risk factors will be most successful in its management...
  62. ncbi Food and drug administration black box warning on the perioperative use of droperidol: a review of the cases
    Ashraf S Habib
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27707, USA
    Anesth Analg 96:1377-9. 2003
  63. ncbi Pharmacodynamic interactions between cisatracurium and rocuronium
    Dara S Breslin
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Anesth Analg 98:107-10, table of contents. 2004
    ..This supports the contention that combinations of structurally dissimilar neuromuscular blocking drugs result in a synergistic effect...
  64. ncbi Perioperative pain management
    Srinivas Pyati
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    CNS Drugs 21:185-211. 2007
    ....
  65. ncbi Pharmacotherapy of postoperative nausea and vomiting
    Ashraf S Habib
    Department of Anesthesiology, Duke University Medical Center, Box 3094, Durham, NC 27710, USA
    Expert Opin Pharmacother 4:457-73. 2003
    ..Finally, recommendations for the prophylaxis and treatment of PONV will be discussed...
  66. ncbi Addition of bevacizumab to irinotecan- and oxaliplatin-based preoperative chemotherapy regimens does not increase morbidity after resection of colorectal liver metastases
    Srinevas K Reddy
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    J Am Coll Surg 206:96-106. 2008
    ..The objective of this retrospective study was to determine if addition of bevacizumab to iri/oxal preoperative chemotherapy increases morbidity after hepatic resection...
  67. ncbi Can succinylcholine be used safely in hyperkalemic patients?
    Adam J Schow
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Anesth Analg 95:119-22, table of contents. 2002
    ..6 mEq/L or greater. All patients survived the anesthetic with no dysrhythmias or other major morbidity documented. Succinylcholine may be appropriate and safe for use in certain patients with moderate hyperkalemia...
  68. ncbi Minimally invasive cardiac output monitoring in the perioperative setting
    Duane J Funk
    Department of Anesthesiology, Division of Critical Care, Duke University Medical Center, Durham, NC 27710, USA
    Anesth Analg 108:887-97. 2009
    ..In this review, we will describe these new devices including the technology, studies on their efficacy and the limitations of their use...
  69. ncbi Combination antiemetics: what is the evidence?
    Ashraf S Habib
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Int Anesthesiol Clin 41:119-44. 2003
  70. ncbi Gabapentin and postoperative pain--a systematic review of randomized controlled trials
    Kok Yuen Ho
    Department of Anesthesiology, Duke University Medical Center, Box 3094, Durham, NC 27710, USA
    Pain 126:91-101. 2006
    ..58; 95% CI 0.39-0.86) and pruritus (Peto OR 0.27; 95% CI 0.10-0.74). In conclusion, gabapentin has an analgesic and opioid-sparing effect in acute postoperative pain management when used in conjunction with opioids...
  71. ncbi Postoperative nausea and vomiting following inpatient surgeries in a teaching hospital: a retrospective database analysis
    Ashraf S Habib
    Duke University Medical Center, Durham, NC 27710, USA
    Curr Med Res Opin 22:1093-9. 2006
    ..CONCLUSIONS: PONV remain a significant problem postoperatively and often persists beyond PACU discharge. The presence of PONV is associated with increased length of PACU stay and greater resource utilization and costs...
  72. ncbi Evidence-based management of postoperative nausea and vomiting: a review
    Ashraf S Habib
    Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina, USA
    Can J Anaesth 51:326-41. 2004
    ..CONCLUSION: PONV are common after anesthesia and surgery. We provided evidence-based guidelines for the management of this problem based on the available literature...
  73. ncbi Regional anesthesia for vascular access surgery
    Elizabeth B Malinzak
    Department of Anesthesiology, Duke University Medical Center, Duke University School of Medicine, Durham, NC 27710, USA
    Anesth Analg 109:976-80. 2009
    ..Anesthetic techniques used in vascular access surgery (monitored anesthesia care, regional blocks, and general anesthesia) may affect these characteristics and fistula failure...
  74. ncbi Comment: Promethazine adverse events after implementation of a medication shortage interchange
    Ashraf S Habib
    Ann Pharmacother 39:1370; author reply 1370-1. 2005
  75. ncbi Effective treatment of laparoscopic cholecystectomy pain with intravenous followed by oral COX-2 specific inhibitor
    Girish P Joshi
    Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9068, USA
    Anesth Analg 98:336-42, table of contents. 2004
    ..v., 30-45 min preoperatively followed by oral valdecoxib 40 mg qd reduced opioid requirements and provided superior pain relief as well as improved patient global evaluation after laparoscopic cholecystectomy...
  76. ncbi The additive interactions between ondansetron and droperidol for preventing postoperative nausea and vomiting
    Matthew T V Chan
    Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong Special Administrative Region
    Anesth Analg 103:1155-62. 2006
    ..Both drugs acted independently of each other through their specific mechanisms of action. The incidence of QTc prolongation did not increase with the drug combination...
  77. ncbi Preventing postoperative nausea and vomiting: post hoc analysis of pooled data from two randomized active-controlled trials of aprepitant
    Pierre Diemunsch
    Hopital de Hautepierre, Strasbourg, France
    Curr Med Res Opin 23:2559-65. 2007
    ..Post hoc analyses of pooled data from these trials were performed to more fully characterize the efficacy profile of aprepitant in terms of nausea and use of rescue therapy...
  78. ncbi Haloperidol for postoperative nausea and vomiting: are we reinventing the wheel?
    Ashraf S Habib
    Anesth Analg 106:1343-5. 2008
  79. ncbi Pro: The Food and Drug Administration Black box warning on droperidol is not justified
    Ashraf S Habib
    Anesth Analg 106:1414-7. 2008
  80. ncbi Postoperative pain experience: results from a national survey suggest postoperative pain continues to be undermanaged
    Jeffrey L Apfelbaum
    Department of Anesthesia and Critical Care, The University Chicago Hospitals, Chicago, Illinois 60637, USA
    Anesth Analg 97:534-40, table of contents. 2003
    ..Approximately 80% of patients experienced pain after surgery. Of these patients, 86% had moderate, severe, or extreme pain. Additional efforts are required to improve patients' postoperative pain experience...
  81. ncbi FDA "black box" warning regarding use of droperidol for postoperative nausea and vomiting: is it justified?
    Tong J Gan
    Anesthesiology 97:287. 2002
  82. ncbi Meta-analysis of the safety of 5-HT3 antagonists with dexamethasone or droperidol for prevention of PONV
    John B Leslie
    College of Medicine, Mayo Clinic, Mayo Clinic Hospital, Mayo Clinic Arizona, Scottsdale, AZ 85259 5404, USA
    Ann Pharmacother 40:856-72. 2006
    ..Physicians have been reluctant to employ these guidelines due to concerns over the black-box warning of droperidol and safety concerns with a steroid...
  83. ncbi Re: Increased body mass index predicts increased blood loss during radical cystectomy
    Philipp Dahm
    J Urol 172:1197-8; author reply 1198. 2004
  84. ncbi Hydroxyethyl starch in balanced electrolyte solution (Hextend)--pharmacokinetic and pharmacodynamic profiles in healthy volunteers
    Nicholas J Wilkes
    Centre for Anaesthesia, Royal Free and University College London School of Medicine, London, UK
    Anesth Analg 94:538-44; table of contents. 2002
    ..This open-label volunteer study demonstrated that it has pharmacokinetic and pharmacodynamic profiles similar to those of established HES...