Research Topics
| Harvey Jay CohenSummaryAffiliation: Duke University Medical Center Country: USA Publications
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Detail Information
Publications
A model for the shared care of elderly patients with cancerHarvey Jay Cohen
Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
J Am Geriatr Soc 57:S300-2. 2009..Degrees of participation will vary over time, depending upon the needs of the patient and family...- The cancer aging interface: a research agendaHarvey Jay Cohen
Department of Medicine, Center for the Study of Aging and Human Development, Duke University Medical Center, Geriatric Research Education and Clinical Center, Veterans Affairs Medical Center, Durham, NC 27710, USA
J Clin Oncol 25:1945-8. 2007..Recommendations for research agendas in each of these areas are offered. In addition, the need for training investigators to work at this interface is addressed... - Coagulation and activation of inflammatory pathways in the development of functional decline and mortality in the elderlyHarvey Jay Cohen
Center for the Study of Aging and Human Development, Claude D Pepper Older Americans Independence Center, Duke University Medical Center, Durham, North Carolina, USA
Am J Med 114:180-7. 2003..This study was performed to determine the effects of markers of inflammation (interleukin 6) and coagulation (D-dimer) on mortality and functional status in older persons... - Reach out to ENhancE Wellness in Older Cancer Survivors (RENEW): design, methods and recruitment challenges of a home-based exercise and diet intervention to improve physical function among long-term survivors of breast, prostate, and colorectal cancerDenise Clutter Snyder
Duke University School of Nursing, Durham, NC 27710, USA
Psychooncology 18:429-39. 2009..Lifestyle interventions may hold promise in reorienting functional decline in older cancer survivors, but few studies have been conducted... - Aging and cancerDebashish Misra
Department of Medicine, Division of Geriatrics, Duke University Medical Center, Durham, NC 27710, USA
Clin Adv Hematol Oncol 2:457-65. 2004..Nevertheless, there is a substantial amount of guidance available, and in this review we will address selected issues of importance when considering the approach to the older cancer patient... - Geriatric evaluation and management units in the care of the frail elderly cancer patientArati V Rao
Geriatric Research, Education and Clinical Center GRECC Veterans Administration Medical Center, and Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, NC 27710, USA
J Gerontol A Biol Sci Med Sci 60:798-803. 2005..Geriatric assessment has been suggested as a possibly useful approach in dealing with frail elderly cancer patients... - Correlation between symptoms and function in older adults with comorbidityHeather E Whitson
Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, North Carolina 27710, USA
J Am Geriatr Soc 57:676-82. 2009.... - Chronic medical conditions and the sex-based disparity in disability: the Cardiovascular Health StudyHeather E Whitson
Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, NC 27710, USA
J Gerontol A Biol Sci Med Sci 65:1325-31. 2010.... - Effect of telephone exercise counseling on frailty in older veterans: project LIFEMatthew J Peterson
Geriatric Research, Education and Clinical Center, Department of Veterans Affairs Medical Center, Durham, NC 27705, USA
Am J Mens Health 1:326-34. 2007..07). There was a clinically meaningful change in frailty status with intensive, telephone exercise counseling. Improvement in frailty status was likely due to improvement in functional limitations... - Impact of anemia on mortality, cognition, and function in community-dwelling elderlySusan D Denny
Department of Medicine, Duke University, Durham, NC, USA
Am J Med 119:327-34. 2006..Anemia also is a risk factor for functional and cognitive decrease... - Function in elderly cancer survivors depends on comorbiditiesKatherine S Garman
Department of Medicine, Division of Geriatrics, and the Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, North Carolina 27710, USA
J Gerontol A Biol Sci Med Sci 58:M1119-24. 2003..Factors associated with functional status in elderly cancer survivors, in particular, comorbidity, have been inadequately studied... - Inpatient care for elderly cancer patients: the role for Geriatric Evaluation and Management Units in fulfilling goals for careKatherine Schuver Garman
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
Crit Rev Oncol Hematol 51:241-7. 2004..In-patient GEMU services represent a promising approach to care for older cancer patients, and deserve further evaluation of benefits and risks... - Effects of home-based diet and exercise on functional outcomes among older, overweight long-term cancer survivors: RENEW: a randomized controlled trialMiriam C Morey
Duke University Older Americans Independence Center, and Department of Medicine, Duke University School of Medicine, Durham, North Carolina 27705, USA
JAMA 301:1883-91. 2009..Lifestyle interventions may provide benefit, but it is unknown whether long-term cancer survivors can modify their lifestyle behaviors sufficiently to improve functional status... - Effects of geriatric evaluation and management on adverse drug reactions and suboptimal prescribing in the frail elderlyKenneth E Schmader
Veterans Affairs Medical Center, Durham, North Carolina, USA
Am J Med 116:394-401. 2004..To determine if inpatient or outpatient geriatric evaluation and management, as compared with usual care, reduces adverse drug reactions and suboptimal prescribing in frail elderly patients... - Effects of cancer history and comorbid conditions on mortality and healthcare use among older cancer survivorsPearl H Seo
Division of Geriatrics, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
Cancer 101:2276-84. 2004..In the current study, the authors set out to assess the effects of cancer history and comorbid conditions on healthcare use and mortality... - Comorbid cognitive impairment and functional trajectories in low vision rehabilitation for macular diseaseHeather E Whitson
Aging Center, Duke University Medical Center, Duke University Medical Center, DUMC 3003, Durham, NC 27710, USA
Aging Clin Exp Res 23:343-50. 2011..This study investigated whether baseline cognitive status predicts functional trajectories among older adults in low vision rehabilitation (LVR) for macular disease... - Is the prevalence of dehydration among community-dwelling older adults really low? Informing current debate over the fluid recommendation for adults aged 70+yearsJodi Dunmeyer Stookey
Center for the Study of Aging and Human Development, Claude D Pepper Older Americans Independence Center, Duke University Medical Center, Box 3003, Durham, NC 27710, USA
Public Health Nutr 8:1275-85. 2005..This study explores whether the low prevalence might reflect limitations of individual dehydration indices... - The effect of comorbid illness on receipt of cancer screening by older peopleMitchell T Heflin
Center for Health Services Research and Geriatrics Research, Education and Clinical Center, VA Medical Center, Durham, North Carolina, USA
J Am Geriatr Soc 50:1651-8. 2002..To identify associations between the type and number of diagnoses and receipt of screening for breast, cervical, and colorectal cancer by older people... - Spirituality across the lifespanHarold G Koenig
Department of Psychiatry and Behavioral Sciences, and the Center for Aging, Duke University Medical Center, Durham, NC 27710, USA
South Med J 99:1157-8. 2006 - A controlled trial of inpatient and outpatient geriatric evaluation and managementHarvey Jay Cohen
Veterans Affairs Medical Center, Durham, NC 27705, USA
N Engl J Med 346:905-12. 2002..There were significant reductions in functional decline with inpatient geriatric evaluation and management and improvements in mental health with outpatient geriatric evaluation and management, with no increase in costs... - Geriatric assessment and comorbidityArati V Rao
Division of Geriatrics, Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, NC 27710, USA
Semin Oncol 31:149-59. 2004..However, the ultimate aim would be to use comorbidity and comprehensive geriatric assessments prospectively in the older cancer patient to help predict the suitability and success of treatment with various antineoplastic modalities... - Fatigue in older cancer patients: etiology, assessment, and treatmentArati V Rao
Division of Medical Oncology and Cell Therapy, Division of Geriatrics, Duke University Medical Center and Durham Veterans Affairs Medical Center, Durham, NC 27710, USA
Semin Oncol 35:633-42. 2008..This review provides a brief overview of CRF in elderly cancer patients and highlights the areas of required research in this patient population... - The cancer and leukemia group B cancer in the elderly committee: addressing a major cancer needHarvey Jay Cohen
Center for the Study of Aging, Duke University Medical Center and Geriatric Research, Education and Clinical Center, Veterans Affairs Medical Center, Durham, North Carolina, USA
Clin Cancer Res 12:3606s-11s. 2006..The Cancer in the Elderly Committee has been successful in developing, implementing, and completing trials in all these areas and serves as a major resource for clinical trials development for the CALGB... - Functional status and the elderly cancer patientKatherine S Garman
Division of Geriatrics, Department of Medicine, Duke University Medical Center, Box 2885, Durham, NC 27710, USA
Crit Rev Oncol Hematol 43:191-208. 2002..There are many different methods available to assess functional status. Individual assessment of functional status in the context of a geriatric assessment may be an important component of the care older cancer patients receive... - Effect of motorized scooters on physical performance and mobility: a randomized clinical trialHelen Hoenig
Physical Medicine and Rehabilitation Service, Durham Veterans Administration Medical Center, and Division of Geriatrics, Department of Medicine, Duke University Medical Center, Durham, NC 27705, USA
Arch Phys Med Rehabil 88:279-86. 2007..To investigate the effects of providing a motorized scooter on physical performance and mobility... - Analysis of age, estimated creatinine clearance and pretreatment hematologic parameters as predictors of fludarabine toxicity in patients treated for chronic lymphocytic leukemia: a CALGB (9011) coordinated intergroup studyRobert E Martell
Geriatrics Research, Education and Clinical Center, Veterans Affairs Medical Center and Hematology/Oncology Division, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
Cancer Chemother Pharmacol 50:37-45. 2002..0001). CONCLUSIONS: Patient age was not an independent risk factor for fludarabine-related toxicity, but CrCl(est) was associated with time to toxicity... - Cross-linked fibrin degradation products (D-dimer), plasma cytokines, and cognitive decline in community-dwelling elderly personsCraig J Wilson
St Vincent Institute on Aging, St Vincent Hospitals and Health Services, Indianapolis, Indiana 46360, USA
J Am Geriatr Soc 51:1374-81. 2003..To investigate the effect of coagulation and inflammatory pathway activation on future cognitive decline in older persons... - Survey of oncologists' perceptions of barriers to accrual of older patients with breast carcinoma to clinical trialsAlice B Kornblith
Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
Cancer 95:989-96. 2002.... - Anemia and cancer in older personsBrenda W Penninx
EMGO Institute, VU University, Medical Center, Amsterdam, Netherlands
J Support Oncol 5:107-13. 2007..Optimizing treatment outcomes in elderly patients with cancer depends on careful determination of performance status as well as the potential of therapies to treat anemia in these patients... - Keynote comment: cancer survivorship and ageing--a double whammyHarvey Jay Cohen
Lancet Oncol 7:882-3. 2006 - Use of comprehensive geriatric assessment in older cancer patients: recommendations from the task force on CGA of the International Society of Geriatric Oncology (SIOG)Martine Extermann
H Lee Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA
Crit Rev Oncol Hematol 55:241-52. 2005..As more and more cancers occur in elderly people, oncologists are increasingly confronted with the necessity of integrating geriatric parameters in the treatment of their patients... - Senior adult oncology clinical practice guidelines in oncologyLodovico Balducci
H. Lee Moffitt Cancer Center and Research Institute, University of South Florida, 12902 Magnolia Drive, Tampa, FL 33612, USA
J Natl Compr Canc Netw 3:572-90. 2005 - Telephone monitoring of distress in patients aged 65 years or older with advanced stage cancer: a cancer and leukemia group B studyAlice B Kornblith
Breast Oncology Program, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
Cancer 107:2706-14. 2006.... - The origin of the word geriatricsHarvey Jay Cohen
J Am Geriatr Soc 51:1676-7. 2003 - Evidence of a relationship between infant birth weight and later diabetes and impaired glucose regulation in a Chinese populationXinhua Xiao
Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China
Diabetes Care 31:483-7. 2008..The aim of this study was to determine the influence of birth weight, a marker of fetal growth, on the development of later impaired glucose metabolism throughout the life span of people living in China... - Duke University School of MedicineHarvey Jay Cohen
Acad Med 79:S37-44. 2004 - Hypertonic hyperglycemia progresses to diabetes faster than normotonic hyperglycemiaJodi Dunmeyer Stookey
Stanford Prevention Research Center, Palo Alto, CA, USA
Eur J Epidemiol 19:935-44. 2004..Further work is needed to pursue plasma hypertonicity as a factor in the progression of elevated plasma glucose to diabetes... - Never too old? Age should not be a barrier to enrollment in cancer clinical trialsMatti S Aapro
Institut Multidisciplinaire d Oncologie, CH 1272 Genolier, Switzerland
Oncologist 10:198-204. 2005..Possible reasons for the disparity, and the resulting clinical consequences, are also considered... - Monitoring the randomized trials of the Women's Health Initiative: the experience of the Data and Safety Monitoring BoardJanet Wittes
Statistics Collaborative, Washington DC, USA
Clin Trials 4:218-34. 2007..This paper describes the dilemmas faced by the DSMB and the considerations it made over the course of its existence. The paper concludes with some recommendations for other DSMBs... - Prevalence of monoclonal gammopathy of undetermined significanceHarvey Jay Cohen
N Engl J Med 354:2832; author reply 2832. 2006