RADU STAN

Summary

Affiliation: Dartmouth Medical School
Country: USA

Publications

  1. ncbi PV1 is a key structural component for the formation of the stomatal and fenestral diaphragms
    Radu V Stan
    Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, California 92093 0651, USA
    Mol Biol Cell 15:3615-30. 2004
  2. ncbi Structure of caveolae
    Radu V Stan
    Angiogenesis Research Center, Department of Pathology, Dartmouth Medical School, One Medical Center Drive, Lebanon, NH 03756, USA
    Biochim Biophys Acta 1746:334-48. 2005
  3. ncbi Structure and function of endothelial caveolae
    RADU VIRGIL STAN
    Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California 92093 0651, USA
    Microsc Res Tech 57:350-64. 2002
  4. ncbi Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice
    You Yang Zhao
    University of California at San Diego, Institute of Molecular Medicine, 9500 Gilman Drive, BSB 0623, La Jolla, CA 92093, USA
    Proc Natl Acad Sci U S A 99:11375-80. 2002
  5. ncbi Fibroblast growth factor 2 endocytosis in endothelial cells proceed via syndecan-4-dependent activation of Rac1 and a Cdc42-dependent macropinocytic pathway
    Eugene Tkachenko
    Angiogenesis Research Center, Department of Medicine, Dartmouth Medical School, One Medical Center Drive, Lebanon, NH 03756, USA
    J Cell Sci 117:3189-99. 2004
  6. ncbi Caveolin-1 interacts directly with dynamin-2
    Qing Yao
    Center for Basic Research in Digestive Diseases, and Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA
    J Mol Biol 348:491-501. 2005

Research Grants

  1. Structure and Function of Endothelial Fenestrae
    RADU VIRGIL STAN; Fiscal Year: 2010
  2. Cellular and Molecular Mechanisms of Vascular Permeability
    RADU STAN; Fiscal Year: 2009
  3. Cellular and Molecular Mechanisms of Vascular Permeability
    RADU STAN; Fiscal Year: 2007
  4. Molecular & functional aspects of vascular permeability
    RADU STAN; Fiscal Year: 2004

Collaborators

  • M A McNiven
  • Jing Chen
  • Qing Yao
  • Eugene Tkachenko
  • You Yang Zhao
  • Hong Cao
  • J Michael McCaffery
  • James D Orth
  • Esther Lutgens
  • Michael Simons
  • Nancy Dalton
  • You-Yang Zhao
  • Yusu Gu
  • Po Hsien Chu
  • Kenneth R Chien
  • John Ross
  • Yang Liu
  • Kirk Peterson
  • Po-Hsien Chu
  • Lian Fan

Detail Information

Publications6

  1. ncbi PV1 is a key structural component for the formation of the stomatal and fenestral diaphragms
    Radu V Stan
    Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, California 92093 0651, USA
    Mol Biol Cell 15:3615-30. 2004
    ..Taken together, these data show that PV1 is a key structural component, necessary for the biogenesis of the stomatal and fenestral diaphragms...
  2. ncbi Structure of caveolae
    Radu V Stan
    Angiogenesis Research Center, Department of Pathology, Dartmouth Medical School, One Medical Center Drive, Lebanon, NH 03756, USA
    Biochim Biophys Acta 1746:334-48. 2005
    ..This review summarizes the data on the structure and components of caveolae and their stomatal diaphragms...
  3. ncbi Structure and function of endothelial caveolae
    RADU VIRGIL STAN
    Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California 92093 0651, USA
    Microsc Res Tech 57:350-64. 2002
    ..This short review will focus on their structure and components, methods used to determine these components, and the role of caveolae in the transendothelial exchanges between blood plasma and the interstitial fluid...
  4. ncbi Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice
    You Yang Zhao
    University of California at San Diego, Institute of Molecular Medicine, 9500 Gilman Drive, BSB 0623, La Jolla, CA 92093, USA
    Proc Natl Acad Sci U S A 99:11375-80. 2002
    ..In addition, the loss of Cav-1 leads to a dramatic increase in systemic NO levels. Our studies provided in vivo evidence that cav-1 is essential for the control of systemic NO levels and normal cardiopulmonary function...
  5. ncbi Fibroblast growth factor 2 endocytosis in endothelial cells proceed via syndecan-4-dependent activation of Rac1 and a Cdc42-dependent macropinocytic pathway
    Eugene Tkachenko
    Angiogenesis Research Center, Department of Medicine, Dartmouth Medical School, One Medical Center Drive, Lebanon, NH 03756, USA
    J Cell Sci 117:3189-99. 2004
    ..Taken together, these results demonstrate that FGF2 endocytosis requires syndecan-4 clustering-dependent activation of Rac1 and the intact CDC42-dependent macropinocytic pathway...
  6. ncbi Caveolin-1 interacts directly with dynamin-2
    Qing Yao
    Center for Basic Research in Digestive Diseases, and Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA
    J Mol Biol 348:491-501. 2005
    ..These studies provide the first evidence for a direct interaction between dynamin and the caveolin coat, and demonstrate a selectivity of one Dyn2 form toward the caveolae-mediated endocytosis...

Research Grants11

  1. Structure and Function of Endothelial Fenestrae
    RADU VIRGIL STAN; Fiscal Year: 2010
    ..The techniques employed are cell isolation, fractionation, biochemical assays, cell free-assays, genetically modified animal models, cell culture, transfections, light and electron microscopy. ..
  2. Cellular and Molecular Mechanisms of Vascular Permeability
    RADU STAN; Fiscal Year: 2009
    ..The techniques employed are cell fractionation, biochemical assays, cell free-assays, in-vivo transport studies, genetically modified animal models, cell culture, transfections, light and electron microscopy. ..
  3. Cellular and Molecular Mechanisms of Vascular Permeability
    RADU STAN; Fiscal Year: 2007
    ..The techniques employed are cell fractionation, biochemical assays, cell free-assays, in-vivo transport studies, genetically modified animal models, cell culture, transfections, light and electron microscopy. ..
  4. Molecular & functional aspects of vascular permeability
    RADU STAN; Fiscal Year: 2004
    ..The techniques employed are cell fractionation, cell free-assays, in-vivo screening methods, two- dimensional electrophoresis, cell culture, transfections, light and electron microscopy. ..