Research Topics
| Sophie Moreau-MarquisSummaryAffiliation: Dartmouth Medical School Country: USA Publications
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Detail Information
Publications
Tobramycin and FDA-approved iron chelators eliminate Pseudomonas aeruginosa biofilms on cystic fibrosis cellsSophie Moreau-Marquis
Department of Physiology, Dartmouth Medical School, Hanover, NH 03755, USA
Am J Respir Cell Mol Biol 41:305-13. 2009..These data suggest that the combined use of tobramycin and FDA-approved iron chelators may be an effective therapy to treat patients with CF and other lung disease characterized by antibiotic-resistant P. aeruginosa biofilms...
The short apical membrane half-life of rescued {Delta}F508-cystic fibrosis transmembrane conductance regulator (CFTR) results from accelerated endocytosis of {Delta}F508-CFTR in polarized human airway epithelial cellsAgnieszka Swiatecka-Urban
Department of Physiology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
J Biol Chem 280:36762-72. 2005....
Pseudomonas aeruginosa inhibits endocytic recycling of CFTR in polarized human airway epithelial cellsAgnieszka Swiatecka-Urban
Department of Physiology, Dartmouth Medical School, 1 Rope Ferry Road, HB 7701, Hanover, NH 03755, USA
Am J Physiol Cell Physiol 290:C862-72. 2006..These data suggest that chronic infection with P. aeruginosa may interfere with therapeutic strategies aimed at increasing the apical membrane expression of DeltaF508-CFTR...
In vitro analysis of tobramycin-treated Pseudomonas aeruginosa biofilms on cystic fibrosis-derived airway epithelial cellsGregory G Anderson
Department of Microbiology and Immunology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
Infect Immun 76:1423-33. 2008..Taken together, our data show that analysis of biofilms on airway cells provides new insights into the interaction of these microbial communities with the host...
The DeltaF508-CFTR mutation results in increased biofilm formation by Pseudomonas aeruginosa by increasing iron availabilitySophie Moreau-Marquis
Department of Physiology, Dartmouth Medical School, Hanover, NH 03755, USA
Am J Physiol Lung Cell Mol Physiol 295:L25-37. 2008..aeruginosa biofilms with a dramatically increased antibiotic resistance. The DeltaF508-CFTR mutation enhances biofilm formation, in part, by increasing Fe release into the apical medium...
Pseudomonas aeruginosa biofilm formation in the cystic fibrosis airwaySophie Moreau-Marquis
Department of Physiology, Dartmouth Medical School, Hanover, NH 03755, USA
Pulm Pharmacol Ther 21:595-9. 2008..We suggest that better in vitro models are required, both to understand the interaction of P. aeruginosa with the host airway, and as models to validate new therapeutics, whether targeted at bacteria or host...
Myosin Vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cellsAgnieszka Swiatecka-Urban
Department of Physiology, Dartmouth Medical School, Dartmouth College, Hanover, New Hampshire 03755, USA
J Biol Chem 282:23725-36. 2007..Taken together, these data indicate that myosin Vb is required for CFTR recycling in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells...
