Research Topics
| Azizul HaqueSummaryAffiliation: Dartmouth Medical School Country: USA Publications
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Detail Information
Publications
Co-infection of malaria and gamma-herpesvirus: exacerbated lung inflammation or cross-protection depends on the stage of viral infectionA Haque
Department of Microbiology and Immunology, Dartmouth Medical School, New Hampshire 03756, USA
Clin Exp Immunol 138:396-404. 2004..Our study provides important fundamental information, which will be of use when devising strategies to combat infections with more than one agent, a situation that often occurs naturally...
Confronting potential influenza A (H5N1) pandemic with better vaccinesAzizul Haque
Centre National de la Recherche Scientifique, Paris, France
Emerg Infect Dis 13:1512-8. 2007..Better understanding of host-virus interaction is essential to identify tools to produce effective vaccines against influenza (H5N1)...
Increased expression of B cell-associated regulatory cytokines by glatiramer acetate in mice with experimental autoimmune encephalomyelitisSakhina Begum-Haque
Department of Medicine, Dartmouth Medical School, Lebanon, NH 03756, USA Multiple Sclerosis Center at Dartmouth College, Lebanon, NH 03756, USA
J Neuroimmunol 219:47-53. 2010..Thus, GA impacts both B cell survival and B cell cytokine production during CNS inflammatory disease in an EAE model...
Augmentation of regulatory B cell activity in experimental allergic encephalomyelitis by glatiramer acetateSakhina Begum-Haque
Department of Medicine, Dartmouth Medical School, Lebanon, NH 03756 Multiple Sclerosis Center Dartmouth College, Hanover, NH 03755, USA
J Neuroimmunol 232:136-44. 2011..Thus B cells can protect against EAE, and GA augments this effect in maintaining immune homeostasis and controlling EAE disease progression...
Downregulation of IL-17 and IL-6 in the central nervous system by glatiramer acetate in experimental autoimmune encephalomyelitisSakhina Begum-Haque
Department of Medicine, Dartmouth Medical School, Lebanon, NH 03756, USA
J Neuroimmunol 204:58-65. 2008..The increased expression of TNF-alpha, IL-6, and IL-17 in CNS of CD25+ depleted animals was suppressed by GA treatment. This study demonstrates that both Th1 polarization and Th17 expression are modulated by GA...
Molecular alterations in glioblastoma: potential targets for immunotherapyAzizul Haque
Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina, USA
Prog Mol Biol Transl Sci 98:187-234. 2011..This review provides a detailed overview concerning genetic alterations in glioblastoma, their effects on Ag and biomarker expression, and the future design of chemoimmunotherapeutics against glioblastoma...
HLA-DM negatively regulates HLA-DR4-restricted collagen pathogenic peptide presentation and T cell recognitionShereen Amria
Department of Microbiology and Immunology, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425, USA
Eur J Immunol 38:1961-70. 2008..These findings suggest that HLA-DM expression in APC controls class II-mediated CII(261-273) peptide/epitope presentation and regulates CD4+ T cell responses to this self epitope, thus potentially influencing CII-dependent autoimmunity...
Invariant chain modulates HLA class II protein recycling and peptide presentation in nonprofessional antigen presenting cellsAzizul Haque
Department of Microbiology and Immunology, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425, USA
Cell Immunol 249:20-9. 2007..Endocytosis of class II molecules was enhanced in cells lacking Ii compared with Ii-expressing APC. These results suggest enhanced reliance on the endocytic recycling pathway for functional class II presentation in nonprofessional APC...
Gamma-IFN-inducible-lysosomal thiol reductase modulates acidic proteases and HLA class II antigen processing in melanomaOliver G Goldstein
Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA
Cancer Immunol Immunother 57:1461-70. 2008..These data suggest that GILT-expressing melanoma cells could prove to be very promising for direct antigen presentation and CD4+ T cell recognition, and may have direct implications for the design of cancer vaccines...
Increased calpain correlates with Th1 cytokine profile in PBMCs from MS patientsSarah A Imam
Department of Neurosciences, Division of Neurology, Medical University of South Carolina, Charleston, SC 29425, USA
J Neuroimmunol 190:139-45. 2007..Calpain inhibitor also reduced degradation of myelin basic protein (MBP) by inhibiting the calpain secreted from MBP-specific T cells. Taken together, these results suggested calpain involvement in Th1/Th2 dysregulation in MS patients...
CD80 binding polyproline helical peptide inhibits T cell activationMythily Srinivasan
Department of Oral Pathology, School of Dentistry, 1121 W Michigan St, Indianapolis 46202, USA
J Biol Chem 280:10149-55. 2005..Structural and functional studies suggest potential therapeutic value for select CD80 competitive antagonist peptides...
