Research Topics
| Alan R SchnedSummaryAffiliation: Dartmouth-Hitchcock Medical Center Country: USA Publications
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Detail Information
Publications
Survival following the diagnosis of noninvasive bladder cancer: WHO/International Society of Urological Pathology versus WHO classification systemsAlan R Schned
Department of Pathology, Dartmouth Medical School, Lebanon, New Hampshire 03756, USA
J Urol 178:1196-200; discussion 1200. 2007..In a large, nonselected population of patients with bladder cancer we rated all incident tumors using each system and compared long-term patient survival...- Histological classification and stage of newly diagnosed bladder cancer in a population-based study from the Northeastern United StatesAlan R Schned
Department of Pathology, Dartmouth Medical School, Hanover, New Hampshire, USA
Scand J Urol Nephrol 42:237-42. 2008..This study evaluated the classification and stage of bladder cancers as part of a population-based epidemiological study of bladder cancer in the Northeastern United States... - Clinical and immunologic effects of intranodal autologous tumor lysate-dendritic cell vaccine with Aldesleukin (Interleukin 2) and IFN-{alpha}2a therapy in metastatic renal cell carcinoma patientsThomas Schwaab
Medical Oncology Immunotherapy Group, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA
Clin Cancer Res 15:4986-92. 2009..To evaluate the clinical and immunologic outcomes of DC (dendritic cell) vaccine with interleukin (IL)-2 and IFN-alpha 2a in metastatic renal cell carcinoma patients... - DNA repair genotype interacts with arsenic exposure to increase bladder cancer riskAngeline S Andrew
Department of Community and Family Medicine, Section of Biostatistics and Epidemiology, Dartmouth Medical School, Lebanon, NH 03756, United States
Toxicol Lett 187:10-4. 2009..01). Haplotype analysis confirmed the association of the XRCC3 241. Thus, double-strand break repair genotype may enhance arsenic associated bladder cancer susceptibility in the U.S. population... - Bladder cancer SNP panel predicts susceptibility and survivalAngeline S Andrew
Section of Biostatistics and Epidemiology, Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, NH 03756, USA
Hum Genet 125:527-39. 2009..8 95% CI 1.1-3.0). Variants in the detoxification gene EPHX1 experienced longer survival (HR 0.4 (95% CI 0.2-0.8). These genes can now be assessed in multiple study populations to identify and validate SNPs appropriate for clinical use... - Arsenic exposure predicts bladder cancer survival in a US populationRyan C Kwong
Section of Biostatistics and Epidemiology, Department of Community and Family Medicine, Norris Cotton Cancer Center, Dartmouth Medical School, 7927 Rubin 860 One Medical Center Drive, Lebanon, NH 03756, USA
World J Urol 28:487-92. 2010..While arsenic is a known carcinogen, recent studies suggest that it is useful as a therapeutic agent for leukemia. This study examined the relationship between arsenic exposure and bladder cancer mortality... - EGFR pathway polymorphisms and bladder cancer susceptibility and prognosisRebecca A Mason
Section of Biostatistics and Epidemiology, Department of Community and Family Medicine, Dartmouth Medical School, One Medical Center Drive, Lebanon, NH 03756, USA
Carcinogenesis 30:1155-60. 2009..Understanding these genetic influences on increased bladder cancer susceptibility and survival may help in cancer prevention, drug development and choice of therapeutic regimen... - Developing a rational tumor vaccine therapy for renal cell carcinoma: immune yin and yangMarc S Ernstoff
Medical Oncology Immunotherapy Group, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
Clin Cancer Res 13:733s-740s. 2007.... - Passive bioelectrical properties for assessing high- and low-grade prostate adenocarcinomaRyan J Halter
Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA
Prostate 71:1759-67. 2011..Because Gleason grading is also based on tissue architecture we explored the hypothesis that the electrical properties might also provide discriminating power between high- and low-Gleason grade cancers... - Concordance of multiple analytical approaches demonstrates a complex relationship between DNA repair gene SNPs, smoking and bladder cancer susceptibilityAngeline S Andrew
Department of Community and Family Medicine, Section of Biostatistics and Epidemiology, Dartmouth Medical School, Lebanon, NH 03756, USA
Carcinogenesis 27:1030-7. 2006..These results support the hypothesis that common polymorphisms in DNA repair genes modify bladder cancer risk and emphasize the need for a multifaceted statistical approach to identify gene-gene and gene-environment interactions... - Polyomavirus infection of the urinary tract presenting as hemorrhagic cystitis in an immunocompetent five-year-old boyJorge L Gonzalez
Department of Pathology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756 0001, USA
Diagn Cytopathol 36:375-8. 2008..Although rare cases of nonhemorrhagic cystitis have been reported, to the best of our knowledge this is the first case of hemorrhagic cystitis occurring in this setting... - Intraperitoneal India ink deposits appearing as endometriosis in a patient with chronic pelvic painKristin K Algoe
Dartmouth Medical School, Dartmouth Hitchcock Medical Center, Departments of Obstetrics and Gynecology and Pathology, Lebanon, NH 03756, USA
Obstet Gynecol 112:448-50. 2008..Visualization and biopsy of suspicious peritoneum can confirm endometriosis. Endoscopic India ink tattooing can lead to peritoneum that visually mimics endometriosis... - Bladder cancer risk and personal hair dye useAngeline S Andrew
Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, NH 03756, USA
Int J Cancer 109:581-6. 2004..In light of the prevalence of hair dye use, further studies are needed that address the effects of specific colors and types of hair dyes along with the possible role of individual susceptibility... - Immunological effects of granulocyte-macrophage colony-stimulating factor and autologous tumor vaccine in patients with renal cell carcinomaThomas Schwaab
Uro-Oncology Group, Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03756-0001, USA
J Urol 171:1036-42. 2004..CONCLUSIONS: GM-CSF and autologous vaccine can be given safely in combination to patients with renal cell cancer. We observed treatment related changes in tumor specific circulating lymphocyte populations... - Electrical impedance spectroscopy of the human prostateRyan J Halter
Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
IEEE Trans Biomed Eng 54:1321-7. 2007..This is in agreement with trends observed in other tissues reported in much of the literature. Expanded studies are needed to further validate this finding and to explore the biological mechanism responsible for generating the results... - Impaired cytolytic activity in peripheral blood T cells from renal cell carcinoma patientsTodd S Crocenzi
Uro-Oncology Program, Norris Cotton Cancer Center and the Section of Hematology/Oncology, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756-0001, USA
Clin Immunol 117:6-11. 2005..8 LU vs. 194.6 LU, P = 0.025). Exposure to rhIL-2 increased T cell-mediated lysis in both groups. Disruption of T cell cytotoxicity in RCC patients can be overcome by exposure to rhIL-2... - Distinct mechanisms of action of anti-CD154 in early versus late treatment of murine lupus nephritisSergio A Quezada
Dartmouth Medical School, Lebanon, New Hampshire 03756, USA
Arthritis Rheum 48:2541-54. 2003..These data demonstrate that CD40-CD154 interactions are critical for the maintenance of autoimmunity and suggest a potential role for anti-CD154 as a therapeutic agent in established human lupus... - Real-time polymerase chain reaction and laser capture microdissection for the diagnosis of BK virus infection in renal allograftsOyedele A Adeyi
Department of Pathology, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA
Am J Clin Pathol 124:537-42. 2005..This technique detected BKV in tubular epithelial cells of renal allografts. To our knowledge, this is the first report of detecting BKV in laser capture microdissected renal biopsy specimens using real-time PCR... - Occupation and bladder cancer risk in a population-based case-control study in New HampshireJoanne S Colt
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Occupational and Environmental Epidemiology Branch, Bethesda, MD 20892 7240, USA
Cancer Causes Control 15:759-69. 2004..To identify occupations with excess bladder cancer risk in New Hampshire, where bladder cancer mortality rates have been elevated for decades... - Epigenetic inactivation of SFRP genes and TP53 alteration act jointly as markers of invasive bladder cancerCarmen J Marsit
Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, Massachusetts 02115, USA
Cancer Res 65:7081-5. 2005..02) controlled for TP53 staining intensity and other survival-associated factors. Classifying tumors based on SFRP methylation status and TP53 protein staining intensity may be a clinically powerful predictor of invasive, deadly disease...