Research Topics
Species | Athos J RassiasSummaryAffiliation: Dartmouth-Hitchcock Medical Center Country: USA Publications
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Detail Information
Publications
Insulin increases neutrophil count and phagocytic capacity after cardiac surgeryAthos J Rassias
Department of Anesthesiology, Dartmouth Medical School, Hanover, New Hampshire 03756, USA
Anesth Analg 94:1113-9, table of contents. 2002....
Cortisol antiinflammatory effects are maximal at postoperative plasma concentrationsMark P Yeager
Department of Anesthesiology, Dartmouth Medical School, Hanover, NH, USA
Crit Care Med 33:1507-12. 2005....
In vivo exposure to high or low cortisol has biphasic effects on inflammatory response pathways of human monocytesMark P Yeager
Department of Anesthesiology, Dartmouth Hitchcock Medical Center, 1 Medical Center Dr, Lebanon, NH 03756, USA
Anesth Analg 107:1726-34. 2008..Since some GC effects on inflammation are stimulatory, we hypothesized that acute in vivo GC depletion would decrease inflammatory responses of human monocytes...
Decreased physiologic variability as a generalized response to human endotoxemiaAthos J Rassias
Department of Anesthesiology, Dartmouth Medical School, Hanover, NH, USA
Crit Care Med 33:512-9. 2005..CONCLUSIONS: Increased regularity, or decreased variability, of organ functions is a generalized response to systemic inflammation that occurs in widely divergent systems during endotoxemia...
Intraoperative management of hyperglycemia in the cardiac surgical patientAthos J Rassias
Dartmouth Medical School, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03755, USA
Semin Thorac Cardiovasc Surg 18:330-8. 2006..In addition, the technique of hyperinsulinemic glucose clamp shows the greatest promise of achieving normoglycemia while on CPB...
Pretreatment with stress cortisol enhances the human systemic inflammatory response to bacterial endotoxinMark P Yeager
Department of Anesthesiology and Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
Crit Care Med 37:2727-32. 2009....
Endotoxin induces rapid metalloproteinase-mediated shedding followed by up-regulation of the monocyte hemoglobin scavenger receptor CD163Katharine A Hintz
Department of Physiology, Dartmouth Medical School, Hanover, New Hampshire, USA
J Leukoc Biol 72:711-7. 2002..As hemoglobin can bind LPS and enhance its toxicity, it will be important to determine how cell surface and soluble CD163 influence inflammatory processes during sepsis...
Glucocorticoid effects on the inflammatory and clinical responses to cardiac surgeryMary P Fillinger
Department of Anesthesiology, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA
J Cardiothorac Vasc Anesth 16:163-9. 2002..CONCLUSION: This study shows significant effects of glucocorticoids on the production of IL-6 and IL-10 in response to cardiac surgery but only minor effects on clinical recovery...
The association between heart rate and in-hospital mortality after coronary artery bypass graft surgeryMary P Fillinger
Department of Anesthesiology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
Anesth Analg 95:1483-8, table of contents. 2002..After adjustment for baseline differences among patients, preinduction heart rate > or =80 bpm was associated with an increased in-hospital mortality after coronary artery bypass graft surgery...
Stress response and optimization of perioperative careAthos J Rassias
Department of Anesthesiology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA
Dis Mon 49:522-54. 2003
Highest core temperature during cardiopulmonary bypass and rate of mediastinitisRobert C Groom
Maine Medical Center, Portland, ME 04102, USA
Perfusion 19:119-25. 2004..9 degrees C during CPB is a significant risk factor for development of mediastinitis. Avoidance of higher temperatures during CPB may lower the risk of mediastinitis for diabetic patients undergoing CABG surgery...
