Research Topics
| Larry J DumontSummaryAffiliation: Dartmouth-Hitchcock Medical Center Country: USA Publications
| Collaborators
|
Detail Information
Publications
Seven-day storage of single-donor platelets: recovery and survival in an autologous transfusion studyLarry J Dumont
Gambro BCT, Inc, Lakewood, Colorado 80215, USA
Transfusion 42:847-54. 2002..Platelet viability then becomes the primary determinant of acceptable storage time. This study evaluates the effectiveness of platelets stored in plasma for 7 days...- Evaluation of proposed FDA criteria for the evaluation of radiolabeled red cell recovery trialsLarry J Dumont
Department of Pathology, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756 0001, USA
Transfusion 48:1053-60. 2008..The percentage of sample groups that passed each and all of the proposed FDA criteria was determined. This procedure was repeated for recovery success thresholds of 75, 70, and 67 percent... - Automated collection of double red blood cell units with a variable-volume separation chamberJames P AuBuchon
Department of Pathology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
Transfusion 48:147-52. 2008..This study sought to document the biochemical and hematologic properties and in vivo recovery of red cells (RBCs) collected via a new device that employed a variable-volume centrifugal separation chamber... - Validation of a microbial detection system for use with ACD-A platelets with PAS III platelet additive solutionLarry J Dumont
Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
Transfusion 51:2219-27. 2011..This study evaluated the performance of the two-bottle BTA testing scheme in the recovery of seeded microorganisms from LR-AP in InterSol-plasma compared to a reference plate culture method... - Screening of single-donor apheresis platelets for bacterial contamination: the PASSPORT study resultsLarry J Dumont
Department of Pathology, Dartmouth Medical School, Lebanon, New Hampshire 03756, USA
Transfusion 50:589-99. 2010.... - Interruption of agitation of platelet concentrates: a multicenter in vitro study by the BEST Collaborative on the effects of shipping plateletsLarry J Dumont
Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA
Transfusion 47:1666-73. 2007..Transported platelets (PLTs) are not under continuous agitation. The aim of this study was to determine whether PLTs shipped between 24 and 48 hours would be able to maintain a pH(22 degrees C) value of 6.5 at the end of 7 days of storage... - In vitro pH effects on in vivo recovery and survival of platelets: an analysis by the BEST CollaborativeLarry J Dumont
Gambro BCT, Lakewood, CO, USA
Transfusion 46:1300-5. 2006..The objective of this study was to evaluate the effect of in vitro pH on the in vivo recovery and survival of autologous PLT products... - Bacterial growth kinetics in ACD-A apheresis platelets: comparison of plasma and PAS III storageLarry J Dumont
Department of Pathology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
Transfusion 51:1079-85. 2011..Our objective was to determine the growth kinetics of bacteria in leukoreduced apheresis platelets (LR-AP) in a platelet (PLT) additive solution (PAS; InterSol, Fenwal, Inc.) compared to LR-AP stored in plasma... - A randomized controlled trial comparing autologous radiolabeled in vivo platelet (PLT) recoveries and survivals of 7-day-stored PLT-rich plasma and buffy coat PLTs from the same subjectsLarry J Dumont
Department of Pathology, Dartmouth Medical School, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
Transfusion 51:1241-8. 2011..We hypothesized that 7-day-stored BC-PLTs would have superior autologous recoveries and survivals compared to PRP-PLTs and that both would meet the Food and Drug Administration (FDA) criteria for poststorage viability... - Autologous transfusion recovery of WBC-reduced high-concentration platelet concentratesLarry J Dumont
Gambro BCT, Inc, 10811 West CollinsAvenue, Lakewood, CO 80215, USA
Transfusion 42:1333-9. 2002..This study evaluates the recovery and survival of high-concentration platelets (HCPs) compared to standard apheresis platelets (APCs) in a double-label autologous human system... - Anaerobic storage of red blood cells in a novel additive solution improves in vivo recoveryLarry J Dumont
Department of Pathology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA
Transfusion 49:458-64. 2009.... - Rejuvenation capacity of red blood cells in additive solutions over long-term storageErin K Meyer
Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA
Transfusion 51:1574-9. 2011..This study was done to assess the response capability of RBCs from 30 to 120 days of storage in three FDA-licensed RBC storage solutions after incubation with a rejuvenating solution of pyruvate, inosine, phosphate, and adenine... - A flow cytometric method for detection and enumeration of low-level, residual red blood cells in platelets and mononuclear cell productsJulie M Santana
R and D, Gambro BCT, Inc, Lakewood, Colorado 80215, USA
Transfusion 46:966-72. 2006..FC should be considered for determining rRBCs in MNC products... - The effects of additive solution pH and metabolic rejuvenation on anaerobic storage of red cellsTatsuro Yoshida
Biomedical Engineering Department, Boston University College of Engineering, Boston, Massachusetts 02215, USA
Transfusion 48:2096-105. 2008..Our objective was to determine whether anaerobic storage with acidified additive solution (AS) coupled with metabolic rejuvenation might further improve the benefits of anaerobic storage... - Seven-day storage of apheresis platelets: report of an in vitro studyLarry J Dumont
Department of Pediatrics, University of Colorado Health Sciences Center, Denver, Colorado, USA
Transfusion 43:143-50. 2003..The objective of this study was to determine the allowable platelet content limits for apheresis platelets stored for 7 days in a platelet storage bag (COBE ELP, Gambro BCT)... - Comparing the efficacy and safety of apheresis and whole blood-derived platelet transfusions: a systematic reviewNancy M Heddle
The Department of Medicine and the Department of Molecular Medicine and Pathology, McMaster University, Hamilton, Ontario, Canada
Transfusion 48:1447-58. 2008....