Lisa Friedman

Summary

Affiliation: Cubist Pharmaceuticals
Country: USA

Publications

  1. ncbi Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial
    Daniel G Lee
    Department of Molecular Biology, Massachusetts General Hospital, Cambridge Street, Boston, Massachusetts 02114, USA
    Genome Biol 7:R90. 2006
  2. ncbi Genetic changes that correlate with reduced susceptibility to daptomycin in Staphylococcus aureus
    Lisa Friedman
    Cubist Pharmaceuticals, Inc, Lexington, MA 02421, USA
    Antimicrob Agents Chemother 50:2137-45. 2006
  3. ncbi Genes involved in matrix formation in Pseudomonas aeruginosa PA14 biofilms
    Lisa Friedman
    Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, MA 02115, USA
    Mol Microbiol 51:675-90. 2004
  4. ncbi Two genetic loci produce distinct carbohydrate-rich structural components of the Pseudomonas aeruginosa biofilm matrix
    Lisa Friedman
    Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, MA 02115, USA
    J Bacteriol 186:4457-65. 2004

Collaborators

  • Jared A Silverman
  • Gang Wu
  • Daniel G Lee
  • Frederick M Ausubel
  • George Grills
  • Jianxin He
  • Nicole T Liberati
  • Li Li
  • Jonathan M Urbach
  • Maude Saucier
  • Sachiko Miyata
  • Lenard T Diggins
  • Rhonda L Feinbaum
  • Kate Montgomery
  • Raju Kucherlapati
  • Laurence G Rahme

Detail Information

Publications4

  1. ncbi Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial
    Daniel G Lee
    Department of Molecular Biology, Massachusetts General Hospital, Cambridge Street, Boston, Massachusetts 02114, USA
    Genome Biol 7:R90. 2006
    ..We therefore propose that virulence in this organism is both multifactorial and combinatorial, the result of a pool of pathogenicity-related genes that interact in various combinations in different genetic backgrounds...
  2. ncbi Genetic changes that correlate with reduced susceptibility to daptomycin in Staphylococcus aureus
    Lisa Friedman
    Cubist Pharmaceuticals, Inc, Lexington, MA 02421, USA
    Antimicrob Agents Chemother 50:2137-45. 2006
    ....
  3. ncbi Genes involved in matrix formation in Pseudomonas aeruginosa PA14 biofilms
    Lisa Friedman
    Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, MA 02115, USA
    Mol Microbiol 51:675-90. 2004
    ..Together, these results suggest that the pel genes are responsible for the production of a glucose-rich matrix material required for the formation of biofilms by P. aeruginosa PA14...
  4. ncbi Two genetic loci produce distinct carbohydrate-rich structural components of the Pseudomonas aeruginosa biofilm matrix
    Lisa Friedman
    Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, MA 02115, USA
    J Bacteriol 186:4457-65. 2004
    ..Either carbohydrate-rich matrix component appears to be sufficient for mature biofilm formation, and at least one of them is required for mature biofilm formation in P. aeruginosa strains PA14 and ZK2870...