Research Topics
| Renato H OrsiSummaryAffiliation: Cornell University Country: USA Publications
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Publications
Short-term genome evolution of Listeria monocytogenes in a non-controlled environmentRenato H Orsi
Department of Food Science, Cornell University, Ithaca, NY, USA
BMC Genomics 9:539. 2008..While a genome sequence for the 1988 food isolate has been reported, we sequenced the genomes of the 1988 human isolate as well as a human and a food isolate from the 2000 outbreak to allow for comparative genome analyses...
Genome-wide analyses reveal lineage specific contributions of positive selection and recombination to the evolution of Listeria monocytogenesRenato H Orsi
Department of Food Science, Cornell University, Ithaca, NY, USA
BMC Evol Biol 8:233. 2008..innocua strain and four L. monocytogenes strains representing lineages I and II, to characterize the contributions of positive selection and recombination to the evolution of the L. innocua/L. monocytogenes core genome...
Homopolymeric tracts represent a general regulatory mechanism in prokaryotesRenato H Orsi
Department of Food Science, Cornell University, Ithaca, NY 14853, USA
BMC Genomics 11:102. 2010..g., phase variation...
Genetic variability and pathogenicity potential of Escherichia coli isolated from recreational water reservoirsRenato H Orsi
Centro de Biologia Molecular e Engenharia Genetica, CP 6010, Universidade Estadual de Campinas, 13083 875 Campinas, SP, Brazil
Res Microbiol 158:420-7. 2007..Colony blot experiments using probes from several virulence factor genes showed that both reservoirs contained potential pathogenic strains and may represent a risk to recreational or household usage of these water resources...
Transcriptomic and phenotypic analyses suggest a network between the transcriptional regulators HrcA and sigmaB in Listeria monocytogenesYuewei Hu
Department of Food Science, 413 Stocking Hall, Cornell University, Ithaca, NY 14853, USA
Appl Environ Microbiol 73:7981-91. 2007..monocytogenes genes...
Comparative genomics of the bacterial genus Listeria: Genome evolution is characterized by limited gene acquisition and limited gene lossHenk C den Bakker
Department of Food Science, Cornell University, Ithaca, NY 14853, USA
BMC Genomics 11:688. 2010....
Complementation of Listeria monocytogenes null mutants with selected Listeria seeligeri virulence genes suggests functional adaptation of Hly and PrfA and considerable diversification of prfA regulation in L. seeligeriCourtney R Lucas Stelling
Graduate Field of Microbiology, Department of Food Science, Cornell University, Ithaca, New York 14853, USA
Appl Environ Microbiol 76:5124-39. 2010..seeligeri and L. monocytogenes. Virulence gene homologues and their expression thus appear to have adapted to distinct but possibly related functions in these two species...
Genome wide evolutionary analyses reveal serotype specific patterns of positive selection in selected Salmonella serotypesYesim Soyer
Department of Food Science, Cornell University, 412 Stocking Hall, Ithaca, NY 14853, USA
BMC Evol Biol 9:264. 2009....
Deep RNA sequencing of L. monocytogenes reveals overlapping and extensive stationary phase and sigma B-dependent transcriptomes, including multiple highly transcribed noncoding RNAsHaley F Oliver
Department of Food Science, Cornell University, Ithaca, NY, USA
BMC Genomics 10:641. 2009....
Lineage specific recombination and positive selection in coding and intragenic regions contributed to evolution of the main Listeria monocytogenes virulence gene clusterRenato H Orsi
Department of Food Science, Cornell University, 412B Stocking Hall, Ithaca, NY 14853, USA
Infect Genet Evol 8:566-76. 2008..monocytogenes virulence gene cluster thus have evolved independently, despite their close physical linkage, likely reflecting distinct selective pressures associated with expression and function of the proteins encoded in this region...
Listeria monocytogenes lineages: Genomics, evolution, ecology, and phenotypic characteristicsRenato H Orsi
Department of Food Science, Cornell University, Ithaca, NY, USA
Int J Med Microbiol 301:79-96. 2011....
A population genetics-based and phylogenetic approach to understanding the evolution of virulence in the genus ListeriaHenk C den Bakker
Department of Food Science, Cornell University, Ithaca, New York 14853, USA
Appl Environ Microbiol 76:6085-100. 2010..Overall, our data suggest that, for some pathogens, loss of virulence genes may represent a selective advantage, possibly by facilitating adaptation to a specific ecological niche...
Listeria monocytogenes internalins are highly diverse and evolved by recombination and positive selectionYeu-Harn L Tsai
Department of Food Science, Cornell University, Ithaca, NY, USA
Infect Genet Evol 6:378-89. 2006..monocytogenes, (iii) both intragenic recombination and positive selection have contributed to the evolution of L. monocytogenes internalins, and (iv) L. monocytogenes internalins show distinct evolutionary histories...
Recombination and positive selection contributed to the evolution of Listeria monocytogenes lineages III and IV, two distinct and well supported uncommon L. monocytogenes lineagesYeu Harn Lucy Tsai
Department of Food Science, Cornell University, Ithaca, NY 14853, USA
Infect Genet Evol 11:1881-90. 2011....
Culture independent analysis of ileal mucosa reveals a selective increase in invasive Escherichia coli of novel phylogeny relative to depletion of Clostridiales in Crohn's disease involving the ileumMartin Baumgart
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14850, USA
ISME J 1:403-18. 2007..coli is involved in the etiopathogenesis to Crohn's disease involving the ileum...
Phenotypic and transcriptomic analyses demonstrate interactions between the transcriptional regulators CtsR and Sigma B in Listeria monocytogenesYuewei Hu
Department of Food Science, 412 Stocking Hall, Cornell University, Ithaca, NY 14853, USA
Appl Environ Microbiol 73:7967-80. 2007..Our data demonstrate that interactions between CtsR and sigma(B) play an important role in L. monocytogenes stress resistance and virulence...
Identification of Escherichia coli from groups A, B1, B2 and D in drinking water in BrazilRenato H Orsi
Centro de Biologia Molecular e Engenharia Genetica, Universidade Estadual de Campinas, C P 6010, 13083 875, Campinas, S P, Brazil
J Water Health 5:323-7. 2007..The results obtained in this work suggest that PCR-based methods can be used for a rapid assessment of potentially pathogenic E. coli strains in water samples...
