RUI H LIU

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. ncbi Antioxidant and antiproliferative activities of common vegetables
    Yi-Fang Chu
    Department of Food Science and Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853, USA
    J Agric Food Chem 50:6910-6. 2002
  2. ncbi Antioxidant activity of apple peels
    Kelly Wolfe
    Institute of Comparative and Environmental Toxicology and Department of Food Science, Stocking Hall, Cornell University, Ithaca, New York 14853-7201, USA
    J Agric Food Chem 51:609-14. 2003
  3. ncbi In vitro digestion and lactase treatment influence uptake of quercetin and quercetin glucoside by the Caco-2 cell monolayer
    Jeanelle Boyer
    Department of Animal Science, Cornell University, Ithaca, New York 14853 7201, USA
    Nutr J 4:1. 2005
  4. ncbi Antiproliferative activity of apples is not due to phenolic-induced hydrogen peroxide formation
    Rui Hai Liu
    Department of Food Science and Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853 7201, USA
    J Agric Food Chem 51:1718-23. 2003
  5. ncbi Potential cell culture models for antioxidant research
    Rui Hai Liu
    Department of Food Science and Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853, USA
    J Agric Food Chem 53:4311-4. 2005
  6. ncbi Potential synergy of phytochemicals in cancer prevention: mechanism of action
    Rui Hai Liu
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    J Nutr 134:3479S-3485S. 2004
  7. ncbi Apples prevent mammary tumors in rats
    Rui Hai Liu
    Department of Food Science, Cornell University, Ithaca, New York 14853 7201, USA
    J Agric Food Chem 53:2341-3. 2005
  8. ncbi Cellular antioxidant activity (CAA) assay for assessing antioxidants, foods, and dietary supplements
    Kelly L Wolfe
    Department of Food Science, Cornell University, Ithaca, New York 14853 7201, USA
    J Agric Food Chem 55:8896-907. 2007
  9. ncbi Cranberry phytochemicals: Isolation, structure elucidation, and their antiproliferative and antioxidant activities
    Xiangjiu He
    Department of Food Science, Stocking Hall, Cornell University, Ithaca, New York 14853-7201, USA
    J Agric Food Chem 54:7069-74. 2006
  10. ncbi Antioxidant and antiproliferative activities of strawberries
    Katherine J Meyers
    Department of Food Science, Cornell University, Ithaca, New York 14853-7201, USA
    J Agric Food Chem 51:6887-92. 2003

Research Grants

Collaborators

  • Xiangjiu He
  • Jie Sun
  • R P Glahn
  • Jeanelle Boyer
  • Jun Yang
  • Jia Ren Liu
  • Bing Qing Chen
  • Kelly L Wolfe
  • Kafui Kwami Adom
  • Yi-Fang Chu
  • Mei Dong
  • Hyungeun Yoon
  • Xianzhong Wu
  • Veronica Dewanto
  • Neal Okarter
  • Ming Wei Zhang
  • Wei Song
  • Columba De La Parra
  • Thudnatkorn Jiratanan
  • Chang-Shu Liu
  • Mark E Sorrells
  • Kelly Wolfe
  • Katherine J Meyers
  • Christopher B Watkins
  • Francesca Boato
  • Ming Liu
  • Gurbuz Gunes
  • M Keshu Liu
  • Christopher M DeRito
  • Fang Xuan Zhang
  • Rui feng Zhang
  • Qingyuan Zhang
  • Xinmei Kang
  • Sergio O Serna Saldivar
  • Marvin P Pritts
  • Courtney Weber
  • Kafui K Adom
  • Janice Brown
  • Xin Qi Li
  • Chang Yong Lee
  • Gary M Wortley

Detail Information

Publications44

  1. ncbi Antioxidant and antiproliferative activities of common vegetables
    Yi-Fang Chu
    Department of Food Science and Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853, USA
    J Agric Food Chem 50:6910-6. 2002
    ..The BI could be a new alternative biomarker for future epidemiological studies in dietary cancer prevention and health promotion...
  2. ncbi Antioxidant activity of apple peels
    Kelly Wolfe
    Institute of Comparative and Environmental Toxicology and Department of Food Science, Stocking Hall, Cornell University, Ithaca, New York 14853-7201, USA
    J Agric Food Chem 51:609-14. 2003
    ..The high content of phenolic compounds, antioxidant activity, and antiproliferative activity of apple peels indicate that they may impart health benefits when consumed and should be regarded as a valuable source of antioxidants...
  3. ncbi In vitro digestion and lactase treatment influence uptake of quercetin and quercetin glucoside by the Caco-2 cell monolayer
    Jeanelle Boyer
    Department of Animal Science, Cornell University, Ithaca, New York 14853 7201, USA
    Nutr J 4:1. 2005
    ..These compounds have a wide range of potential health benefits, and understanding the bioavailability of flavonoids from foods is becoming increasingly important...
  4. ncbi Antiproliferative activity of apples is not due to phenolic-induced hydrogen peroxide formation
    Rui Hai Liu
    Department of Food Science and Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853 7201, USA
    J Agric Food Chem 51:1718-23. 2003
    ..In addition, H(2)O(2) added to the culture medium at 100 microM did not cause inhibition of cell proliferation in either HepG(2) liver cancer cells or Caco-2 colon cancer cells in vitro...
  5. ncbi Potential cell culture models for antioxidant research
    Rui Hai Liu
    Department of Food Science and Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853, USA
    J Agric Food Chem 53:4311-4. 2005
    ....
  6. ncbi Potential synergy of phytochemicals in cancer prevention: mechanism of action
    Rui Hai Liu
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    J Nutr 134:3479S-3485S. 2004
    ....
  7. ncbi Apples prevent mammary tumors in rats
    Rui Hai Liu
    Department of Food Science, Cornell University, Ithaca, New York 14853 7201, USA
    J Agric Food Chem 53:2341-3. 2005
    ..This study demonstrated that whole apple extracts effectively inhibited mammary cancer growth in the rat model; thus, consumption of apples may be an effective strategy for cancer protection...
  8. ncbi Cellular antioxidant activity (CAA) assay for assessing antioxidants, foods, and dietary supplements
    Kelly L Wolfe
    Department of Food Science, Cornell University, Ithaca, New York 14853 7201, USA
    J Agric Food Chem 55:8896-907. 2007
    ..The CAA assay is a more biologically relevant method than the popular chemistry antioxidant activity assays because it accounts for some aspects of uptake, metabolism, and location of antioxidant compounds within cells...
  9. ncbi Cranberry phytochemicals: Isolation, structure elucidation, and their antiproliferative and antioxidant activities
    Xiangjiu He
    Department of Food Science, Stocking Hall, Cornell University, Ithaca, New York 14853-7201, USA
    J Agric Food Chem 54:7069-74. 2006
    ..These results showed cranberry phytochemical extracts have potent antioxidant and antiproliferative activities...
  10. ncbi Antioxidant and antiproliferative activities of strawberries
    Katherine J Meyers
    Department of Food Science, Cornell University, Ithaca, New York 14853-7201, USA
    J Agric Food Chem 51:6887-92. 2003
    ..No relationship was found between antiproliferative activity and antioxidant content...
  11. ncbi Varietal differences in phenolic content and antioxidant and antiproliferative activities of onions
    Jun Yang
    Department of Food Science and Institute of Comparative and Environmental Toxicology, Stocking Hall, Cornell University, Ithaca, New York 14853, USA
    J Agric Food Chem 52:6787-93. 2004
    ..These results may influence consumers toward purchasing onion varieties exhibiting greater potential health benefits and may significantly affect future breeding efforts to enhance onion nutritional qualities...
  12. ncbi Uptake of quercetin and quercetin 3-glucoside from whole onion and apple peel extracts by Caco-2 cell monolayers
    Jeanelle Boyer
    Departments of Food Science and Animal Science, Cornell University, Ithaca, New York 14853 7201, USA
    J Agric Food Chem 52:7172-9. 2004
    ..This use of the Caco2 cell model appears to be a simple and useful system for studying bioavailability of whole food phytochemicals and may be used to assess differences in bioavailability between foods...
  13. ncbi Synergistic effect of apple extracts and quercetin 3-beta-d-glucoside combination on antiproliferative activity in MCF-7 human breast cancer cells in vitro
    Jun Yang
    Department of Food Science, Cornell University, Ithaca, NY 14853 7201, USA
    J Agric Food Chem 57:8581-6. 2009
    ..03 +/- 0.55 and 4.28 +/- 0.39-fold, respectively. The results suggest that the apple extracts plus Q3G combination possesses a synergistic effect in MCF-7 cell proliferation...
  14. ncbi Antioxidant and antiproliferative activities of raspberries
    Ming Liu
    Department of Food Science and Institute of Comparative and Environmental Toxicology, Stocking Hall, Cornell University, Ithaca, New York 14853, USA
    J Agric Food Chem 50:2926-30. 2002
    ..01). No relationship was found between antiproliferative activity and the total amount of phenolics/flavonoids found in the same raspberry (p > 0.05)...
  15. ncbi Health benefits of fruit and vegetables are from additive and synergistic combinations of phytochemicals
    Rui Hai Liu
    Department of Food Science and the Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, NY 14853, USA
    Am J Clin Nutr 78:517S-520S. 2003
    ....
  16. ncbi Phytochemicals of apple peels: isolation, structure elucidation, and their antiproliferative and antioxidant activities
    Xiangjiu He
    Department of Food Science and Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853, USA
    J Agric Food Chem 56:9905-10. 2008
    ..These results showed apple peel phytochemicals have potent antioxidant and antiproliferative activities...
  17. ncbi Antioxidant and antiproliferative activities of common fruits
    Jie Sun
    Department of Food Science, Cornell University, Ithaca, New York 14853-7201, USA
    J Agric Food Chem 50:7449-54. 2002
    ..A bioactivity index (BI) for dietary cancer prevention is proposed to provide a new alternative biomarker for future epidemiological studies in dietary cancer prevention and health promotion...
  18. ncbi Phytochemicals of black bean seed coats: isolation, structure elucidation, and their antiproliferative and antioxidative activities
    Mei Dong
    Department of Food Science, Stocking Hall, Cornell University, Ithaca, New York 14853 7201, USA
    J Agric Food Chem 55:6044-51. 2007
    ..9 microM, respectively. Six flavonoids (compounds 14-19) showed potent antioxidant activity. These results showed the phytochemical extracts of black bean seed coats have potent antioxidant and antiproliferative activities...
  19. ncbi Apple phytochemical extracts inhibit proliferation of estrogen-dependent and estrogen-independent human breast cancer cells through cell cycle modulation
    Jie Sun
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    J Agric Food Chem 56:11661-7. 2008
    ..These results suggest that the antiproliferative activities of apple phytochemical extracts toward human breast cancer cells might be due to the modulation effects on cell cycle machinery...
  20. ncbi Cellular antioxidant activity of common fruits
    Kelly L Wolfe
    Department of Food Science, Cornell University, Ithaca, New York 14853 7201, USA
    J Agric Food Chem 56:8418-26. 2008
    ..Increasing fruit consumption is a logical strategy to increase antioxidant intake and decrease oxidative stress and may lead to reduced risk of cancer...
  21. ncbi Apple peels as a value-added food ingredient
    Kelly L Wolfe
    Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853-7201, USA
    J Agric Food Chem 51:1676-83. 2003
    ..88 +/- 0.01 mg/mL. This was lower than the EC(50) exhibited by the fresh apple peels (p < 0.05). Apple peel powder may be used in a various food products to add phytochemicals and promote good health...
  22. ncbi Fresh apples suppress mammary carcinogenesis and proliferative activity and induce apoptosis in mammary tumors of the Sprague-Dawley rat
    Jia Ren Liu
    Department of Food Science and Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853 7201, USA
    J Agric Food Chem 57:297-304. 2009
    ..These results demonstrate the potent capacity of fresh apples to suppress DMBA-initiated mammary cancers in rats...
  23. ncbi Cytotoxic biotransformed products from cinobufagin by Mucor spinosus and Aspergillus Niger
    Xiangjiu He
    Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou, China
    Steroids 71:392-402. 2006
    ....
  24. ncbi Assessment of carotenoid bioavailability of whole foods using a Caco-2 cell culture model coupled with an in vitro digestion
    Chang-Shu Liu
    Department of Food Science and Institute of Comparative and Environmental Toxicology, Stocking Hall, Cornell University, Ithaca, New York 14853, USA
    J Agric Food Chem 52:4330-7. 2004
    ..These results support the feasibility of the in vitro digestion cell model for assessing carotenoid absorption from whole foods as a suitable and cost-effective physiological alternative to current methodologies...
  25. ncbi Effect of selected phytochemicals and apple extracts on NF-kappaB activation in human breast cancer MCF-7 cells
    Hyungeun Yoon
    Department of Food Science and Institute of Comparative and Environmental Toxicology, 108 Stocking Hall, Cornell University, Ithaca, New York 14853 7201, USA
    J Agric Food Chem 55:3167-73. 2007
    ..05). These results suggest that apple extracts and curcumin have the capabilities of inhibiting TNF-alpha-induced NF-kappaB activation of MCF-7 cells by inhibiting the proteasomal activities instead of IkappaB kinase (IKK) activation...
  26. ncbi Red grape juice inhibits iron availability: application of an in vitro digestion/caco-2 cell model
    Francesca Boato
    Institute of Food Science, Cornell University, Ithaca, New York 14853, USA
    J Agric Food Chem 50:6935-8. 2002
    ..Consumers should be aware that the compounds that inhibit Fe availability are also linked to anticancer benefits; thus, a dietary balance of the above juices may be optimal...
  27. ncbi Phytochemical profiles and antioxidant activity of wheat varieties
    Kafui Kwami Adom
    Departments of Food Science and Plant Breeding and Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853-7201, USA
    J Agric Food Chem 51:7825-34. 2003
    ..Such large genotypic differences in carotenoid content may open up new opportunities for breeding wheat varieties with higher nutritional value...
  28. ncbi Effect of 2alpha-hydroxyursolic acid on NF-kappaB activation induced by TNF-alpha in human breast cancer MCF-7 cells
    Hyungeun Yoon
    Department of Food Science, Cornell University, Ithaca, New York 14853 7201, USA
    J Agric Food Chem 56:8412-7. 2008
    ..05). These results suggest that 2alpha-hydroxyursolic acid has antiproliferative activities against MCF-7 cells and capabilities inhibiting NF-kappaB activation induced by TNF-alpha partially by suppressing proteasome activities...
  29. ncbi Novel low-density lipoprotein (LDL) oxidation model: antioxidant capacity for the inhibition of LDL oxidation
    Yi-Fang Chu
    Department of Food Science and Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853, USA
    J Agric Food Chem 52:6818-23. 2004
    ..The food-specific LOMAC values will be very useful as a new alternative biomarker for future epidemiological studies of cardiovascular disease...
  30. ncbi Sodium borohydride/chloranil-based assay for quantifying total flavonoids
    Xiangjiu He
    Department of Food Science, Cornell University, Ithaca, New York 14853 7201, USA
    J Agric Food Chem 56:9337-44. 2008
    ..This novel SBC total flavonoid assay can be widely used to measure the total flavonoid content of fruits, vegetables, whole grains, herbal products, dietary supplements, and nutraceutical products...
  31. ncbi Triterpenoids isolated from apple peels have potent antiproliferative activity and may be partially responsible for apple's anticancer activity
    Xiangjiu He
    Department of Food Science and Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853, USA
    J Agric Food Chem 55:4366-70. 2007
    ..These results showed the triterpenoids isolated from apple peels have potent antiproliferative activity and may be partially responsible for the anticancer activities of whole apples...
  32. ncbi Processed sweet corn has higher antioxidant activity
    Veronica Dewanto
    Department of Food Science and Institute of Comparative and Environmental Toxicology, Stocking Hall, Cornell University, Ithaca, New York 14853, USA
    J Agric Food Chem 50:4959-64. 2002
    ..This information may have a significant impact on consumers' food selection by increasing their consumption of fruits and vegetables to reduce the risk of chronic diseases...
  33. ncbi Cellular antioxidant activity of common vegetables
    Wei Song
    Department of Food Science, Cornell University, Ithaca, New York 14853 7201, USA
    J Agric Food Chem 58:6621-9. 2010
    ..Increased fruit and vegetable consumption is an effective strategy to increase antioxidant intake and decrease oxidative stress and may lead to reduced risk of developing chronic diseases, such as cancer and cardiovascular disease...
  34. ncbi Structure-activity relationships of flavonoids in the cellular antioxidant activity assay
    Kelly L Wolfe
    Department of Food Science, Cornell University, Ithaca, New York 14853 7201, USA
    J Agric Food Chem 56:8404-11. 2008
    ..ORAC values for flavonoids were not related to their CAA values. Knowledge of structure-activity relationships in the CAA assay may be helpful in assessing potential in vivo antioxidant activity of flavonoids...
  35. ncbi Antioxidant activity of grains
    Kafui Kwami Adom
    Department of Food Science, Cornell University, Stocking Hall, Ithaca, New York 14853-7201, USA
    J Agric Food Chem 50:6182-7. 2002
    ..This may partly explain the mechanism of grain consumption in the prevention of colon cancer, other digestive cancers, breast cancer, and prostate cancer, which is supported by epidemiological studies...
  36. ncbi Phenolic profiles and antioxidant activity of black rice bran of different commercially available varieties
    Ming Wei Zhang
    Department of Food Science, Cornell University, Ithaca, New York 14853 7201, USA
    J Agric Food Chem 58:7580-7. 2010
    ..Knowing the phytochemical profile and antioxidant activity of black rice bran gives insights to its potential application to promote health...
  37. ncbi Effect of processing on the phytochemical profiles and antioxidant activity of corn for production of masa, tortillas, and tortilla chips
    Columba De La Parra
    Department of Food Science, Cornell University, Ithaca, New York 14853 7201, USA
    J Agric Food Chem 55:4177-83. 2007
    ..These findings suggest that lime-cooking significantly reduced the phytochemical content of nixtamalized products but released phenolics and ferulic acid...
  38. ncbi Phytochemicals and antioxidant activity of milled fractions of different wheat varieties
    Kafui Kwami Adom
    Department of Food Science, Cornell University, Ithaca, New York 14853-7201, USA
    J Agric Food Chem 53:2297-306. 2005
    ..These findings provide information necessary for evaluating contributions to good health and disease prevention from whole-wheat consumption...
  39. ncbi Thermal processing enhances the nutritional value of tomatoes by increasing total antioxidant activity
    Veronica Dewanto
    Department of Food Science and Institute of Comparative and Environmental Toxicology, Stocking Hall, Cornell University, Ithaca, New York 14853, USA
    J Agric Food Chem 50:3010-4. 2002
    ..This information may have a significant impact on consumers' food selection by increasing their consumption of fruits and vegetables to reduce the risks of chronic diseases...
  40. ncbi Rapid peroxyl radical scavenging capacity (PSC) assay for assessing both hydrophilic and lipophilic antioxidants
    Kafui Kwami Adom
    Department of Food Science, Cornell University, Ithaca, New York 14853-7201, USA
    J Agric Food Chem 53:6572-80. 2005
    ..The PSC assay can be routinely used to analyze or screen both hydrophilic and lipophilic antioxidants or food extracts and will be a valuable alternative biomarker for future epidemiological studies of chronic diseases...
  41. ncbi Health benefits of whole grain phytochemicals
    Neal Okarter
    Department of Food Science, Cornell University, Ithaca, NY 14853 7201, USA
    Crit Rev Food Sci Nutr 50:193-208. 2010
    ..In this paper, whole grain phytochemicals and the health benefits associated with their consumption are reviewed...
  42. ncbi Cranberries inhibit LDL oxidation and induce LDL receptor expression in hepatocytes
    Yi-Fang Chu
    Department of Food Science, Stocking Hall, Cornell University, Ithaca, NY 14853-7201, United States
    Life Sci 77:1892-901. 2005
    ..We propose that additive or synergistic effects of phytochemicals in cranberries are responsible for the inhibition of LDL oxidation, the induced expression of LDL receptors, and the increased uptake of cholesterol in hepatocytes...
  43. ncbi Antioxidant activity of processed table beets (Beta vulgaris var, conditiva) and green beans (Phaseolus vulgaris L.)
    Thudnatkorn Jiratanan
    Department of Food Science and Institute of Comparative and Environmental Toxicology, Stocking Hall, Cornell University, Ithaca, New York 14853, USA
    J Agric Food Chem 52:2659-70. 2004
    ..It also reinforces the concept that optimal health benefits may be achieved when a wide variety of plant foods (fruits, vegetables and whole grains) and preparation methods are incorporated into the diet...
  44. ncbi Controlled-atmosphere effects on postharvest quality and antioxidant activity of cranberry fruits
    Gurbuz Gunes
    Department of Food Engineering, Istanbul Technical University, Istanbul, Turkey
    J Agric Food Chem 50:5932-8. 2002
    ..However, the total antioxidant activity of the fruits increased overall by about 45% in fruits stored in air. This increase was prevented by storage in 30% CO(2) plus 21% O(2)...

Research Grants1