Research Topics
| RUI H LIUSummaryAffiliation: Cornell University Country: USA Publications
Research Grants
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Detail Information
Publications
Antioxidant and antiproliferative activities of common vegetablesYi-Fang Chu
Department of Food Science and Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853, USA
J Agric Food Chem 50:6910-6. 2002..The BI could be a new alternative biomarker for future epidemiological studies in dietary cancer prevention and health promotion...
Antioxidant activity of apple peelsKelly Wolfe
Institute of Comparative and Environmental Toxicology and Department of Food Science, Stocking Hall, Cornell University, Ithaca, New York 14853-7201, USA
J Agric Food Chem 51:609-14. 2003..The high content of phenolic compounds, antioxidant activity, and antiproliferative activity of apple peels indicate that they may impart health benefits when consumed and should be regarded as a valuable source of antioxidants...
In vitro digestion and lactase treatment influence uptake of quercetin and quercetin glucoside by the Caco-2 cell monolayerJeanelle Boyer
Department of Animal Science, Cornell University, Ithaca, New York 14853 7201, USA
Nutr J 4:1. 2005..These compounds have a wide range of potential health benefits, and understanding the bioavailability of flavonoids from foods is becoming increasingly important...
Antiproliferative activity of apples is not due to phenolic-induced hydrogen peroxide formationRui Hai Liu
Department of Food Science and Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853 7201, USA
J Agric Food Chem 51:1718-23. 2003..In addition, H(2)O(2) added to the culture medium at 100 microM did not cause inhibition of cell proliferation in either HepG(2) liver cancer cells or Caco-2 colon cancer cells in vitro...
Potential cell culture models for antioxidant researchRui Hai Liu
Department of Food Science and Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853, USA
J Agric Food Chem 53:4311-4. 2005....
Potential synergy of phytochemicals in cancer prevention: mechanism of actionRui Hai Liu
Department of Food Science, Cornell University, Ithaca, NY 14853, USA
J Nutr 134:3479S-3485S. 2004....
Apples prevent mammary tumors in ratsRui Hai Liu
Department of Food Science, Cornell University, Ithaca, New York 14853 7201, USA
J Agric Food Chem 53:2341-3. 2005..This study demonstrated that whole apple extracts effectively inhibited mammary cancer growth in the rat model; thus, consumption of apples may be an effective strategy for cancer protection...
Cellular antioxidant activity (CAA) assay for assessing antioxidants, foods, and dietary supplementsKelly L Wolfe
Department of Food Science, Cornell University, Ithaca, New York 14853 7201, USA
J Agric Food Chem 55:8896-907. 2007..The CAA assay is a more biologically relevant method than the popular chemistry antioxidant activity assays because it accounts for some aspects of uptake, metabolism, and location of antioxidant compounds within cells...
Cranberry phytochemicals: Isolation, structure elucidation, and their antiproliferative and antioxidant activitiesXiangjiu He
Department of Food Science, Stocking Hall, Cornell University, Ithaca, New York 14853-7201, USA
J Agric Food Chem 54:7069-74. 2006..These results showed cranberry phytochemical extracts have potent antioxidant and antiproliferative activities...
Antioxidant and antiproliferative activities of strawberriesKatherine J Meyers
Department of Food Science, Cornell University, Ithaca, New York 14853-7201, USA
J Agric Food Chem 51:6887-92. 2003..No relationship was found between antiproliferative activity and antioxidant content...
Varietal differences in phenolic content and antioxidant and antiproliferative activities of onionsJun Yang
Department of Food Science and Institute of Comparative and Environmental Toxicology, Stocking Hall, Cornell University, Ithaca, New York 14853, USA
J Agric Food Chem 52:6787-93. 2004..These results may influence consumers toward purchasing onion varieties exhibiting greater potential health benefits and may significantly affect future breeding efforts to enhance onion nutritional qualities...
Uptake of quercetin and quercetin 3-glucoside from whole onion and apple peel extracts by Caco-2 cell monolayersJeanelle Boyer
Departments of Food Science and Animal Science, Cornell University, Ithaca, New York 14853 7201, USA
J Agric Food Chem 52:7172-9. 2004..This use of the Caco2 cell model appears to be a simple and useful system for studying bioavailability of whole food phytochemicals and may be used to assess differences in bioavailability between foods...
Synergistic effect of apple extracts and quercetin 3-beta-d-glucoside combination on antiproliferative activity in MCF-7 human breast cancer cells in vitroJun Yang
Department of Food Science, Cornell University, Ithaca, NY 14853 7201, USA
J Agric Food Chem 57:8581-6. 2009..03 +/- 0.55 and 4.28 +/- 0.39-fold, respectively. The results suggest that the apple extracts plus Q3G combination possesses a synergistic effect in MCF-7 cell proliferation...
Antioxidant and antiproliferative activities of raspberriesMing Liu
Department of Food Science and Institute of Comparative and Environmental Toxicology, Stocking Hall, Cornell University, Ithaca, New York 14853, USA
J Agric Food Chem 50:2926-30. 2002..01). No relationship was found between antiproliferative activity and the total amount of phenolics/flavonoids found in the same raspberry (p > 0.05)...
Health benefits of fruit and vegetables are from additive and synergistic combinations of phytochemicalsRui Hai Liu
Department of Food Science and the Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, NY 14853, USA
Am J Clin Nutr 78:517S-520S. 2003....
Phytochemicals of apple peels: isolation, structure elucidation, and their antiproliferative and antioxidant activitiesXiangjiu He
Department of Food Science and Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853, USA
J Agric Food Chem 56:9905-10. 2008..These results showed apple peel phytochemicals have potent antioxidant and antiproliferative activities...
Antioxidant and antiproliferative activities of common fruitsJie Sun
Department of Food Science, Cornell University, Ithaca, New York 14853-7201, USA
J Agric Food Chem 50:7449-54. 2002..A bioactivity index (BI) for dietary cancer prevention is proposed to provide a new alternative biomarker for future epidemiological studies in dietary cancer prevention and health promotion...
Phytochemicals of black bean seed coats: isolation, structure elucidation, and their antiproliferative and antioxidative activitiesMei Dong
Department of Food Science, Stocking Hall, Cornell University, Ithaca, New York 14853 7201, USA
J Agric Food Chem 55:6044-51. 2007..9 microM, respectively. Six flavonoids (compounds 14-19) showed potent antioxidant activity. These results showed the phytochemical extracts of black bean seed coats have potent antioxidant and antiproliferative activities...
Apple phytochemical extracts inhibit proliferation of estrogen-dependent and estrogen-independent human breast cancer cells through cell cycle modulationJie Sun
Department of Food Science, Cornell University, Ithaca, New York 14853, USA
J Agric Food Chem 56:11661-7. 2008..These results suggest that the antiproliferative activities of apple phytochemical extracts toward human breast cancer cells might be due to the modulation effects on cell cycle machinery...
Cellular antioxidant activity of common fruitsKelly L Wolfe
Department of Food Science, Cornell University, Ithaca, New York 14853 7201, USA
J Agric Food Chem 56:8418-26. 2008..Increasing fruit consumption is a logical strategy to increase antioxidant intake and decrease oxidative stress and may lead to reduced risk of cancer...
Apple peels as a value-added food ingredientKelly L Wolfe
Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853-7201, USA
J Agric Food Chem 51:1676-83. 2003..88 +/- 0.01 mg/mL. This was lower than the EC(50) exhibited by the fresh apple peels (p < 0.05). Apple peel powder may be used in a various food products to add phytochemicals and promote good health...
Fresh apples suppress mammary carcinogenesis and proliferative activity and induce apoptosis in mammary tumors of the Sprague-Dawley ratJia Ren Liu
Department of Food Science and Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853 7201, USA
J Agric Food Chem 57:297-304. 2009..These results demonstrate the potent capacity of fresh apples to suppress DMBA-initiated mammary cancers in rats...
Cytotoxic biotransformed products from cinobufagin by Mucor spinosus and Aspergillus NigerXiangjiu He
Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou, China
Steroids 71:392-402. 2006....
Assessment of carotenoid bioavailability of whole foods using a Caco-2 cell culture model coupled with an in vitro digestionChang-Shu Liu
Department of Food Science and Institute of Comparative and Environmental Toxicology, Stocking Hall, Cornell University, Ithaca, New York 14853, USA
J Agric Food Chem 52:4330-7. 2004..These results support the feasibility of the in vitro digestion cell model for assessing carotenoid absorption from whole foods as a suitable and cost-effective physiological alternative to current methodologies...
Effect of selected phytochemicals and apple extracts on NF-kappaB activation in human breast cancer MCF-7 cellsHyungeun Yoon
Department of Food Science and Institute of Comparative and Environmental Toxicology, 108 Stocking Hall, Cornell University, Ithaca, New York 14853 7201, USA
J Agric Food Chem 55:3167-73. 2007..05). These results suggest that apple extracts and curcumin have the capabilities of inhibiting TNF-alpha-induced NF-kappaB activation of MCF-7 cells by inhibiting the proteasomal activities instead of IkappaB kinase (IKK) activation...
Red grape juice inhibits iron availability: application of an in vitro digestion/caco-2 cell modelFrancesca Boato
Institute of Food Science, Cornell University, Ithaca, New York 14853, USA
J Agric Food Chem 50:6935-8. 2002..Consumers should be aware that the compounds that inhibit Fe availability are also linked to anticancer benefits; thus, a dietary balance of the above juices may be optimal...
Phytochemical profiles and antioxidant activity of wheat varietiesKafui Kwami Adom
Departments of Food Science and Plant Breeding and Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853-7201, USA
J Agric Food Chem 51:7825-34. 2003..Such large genotypic differences in carotenoid content may open up new opportunities for breeding wheat varieties with higher nutritional value...
Effect of 2alpha-hydroxyursolic acid on NF-kappaB activation induced by TNF-alpha in human breast cancer MCF-7 cellsHyungeun Yoon
Department of Food Science, Cornell University, Ithaca, New York 14853 7201, USA
J Agric Food Chem 56:8412-7. 2008..05). These results suggest that 2alpha-hydroxyursolic acid has antiproliferative activities against MCF-7 cells and capabilities inhibiting NF-kappaB activation induced by TNF-alpha partially by suppressing proteasome activities...
Novel low-density lipoprotein (LDL) oxidation model: antioxidant capacity for the inhibition of LDL oxidationYi-Fang Chu
Department of Food Science and Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853, USA
J Agric Food Chem 52:6818-23. 2004..The food-specific LOMAC values will be very useful as a new alternative biomarker for future epidemiological studies of cardiovascular disease...
Sodium borohydride/chloranil-based assay for quantifying total flavonoidsXiangjiu He
Department of Food Science, Cornell University, Ithaca, New York 14853 7201, USA
J Agric Food Chem 56:9337-44. 2008..This novel SBC total flavonoid assay can be widely used to measure the total flavonoid content of fruits, vegetables, whole grains, herbal products, dietary supplements, and nutraceutical products...
Triterpenoids isolated from apple peels have potent antiproliferative activity and may be partially responsible for apple's anticancer activityXiangjiu He
Department of Food Science and Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 14853, USA
J Agric Food Chem 55:4366-70. 2007..These results showed the triterpenoids isolated from apple peels have potent antiproliferative activity and may be partially responsible for the anticancer activities of whole apples...
Processed sweet corn has higher antioxidant activityVeronica Dewanto
Department of Food Science and Institute of Comparative and Environmental Toxicology, Stocking Hall, Cornell University, Ithaca, New York 14853, USA
J Agric Food Chem 50:4959-64. 2002..This information may have a significant impact on consumers' food selection by increasing their consumption of fruits and vegetables to reduce the risk of chronic diseases...
Cellular antioxidant activity of common vegetablesWei Song
Department of Food Science, Cornell University, Ithaca, New York 14853 7201, USA
J Agric Food Chem 58:6621-9. 2010..Increased fruit and vegetable consumption is an effective strategy to increase antioxidant intake and decrease oxidative stress and may lead to reduced risk of developing chronic diseases, such as cancer and cardiovascular disease...
Structure-activity relationships of flavonoids in the cellular antioxidant activity assayKelly L Wolfe
Department of Food Science, Cornell University, Ithaca, New York 14853 7201, USA
J Agric Food Chem 56:8404-11. 2008..ORAC values for flavonoids were not related to their CAA values. Knowledge of structure-activity relationships in the CAA assay may be helpful in assessing potential in vivo antioxidant activity of flavonoids...
Antioxidant activity of grainsKafui Kwami Adom
Department of Food Science, Cornell University, Stocking Hall, Ithaca, New York 14853-7201, USA
J Agric Food Chem 50:6182-7. 2002..This may partly explain the mechanism of grain consumption in the prevention of colon cancer, other digestive cancers, breast cancer, and prostate cancer, which is supported by epidemiological studies...
Phenolic profiles and antioxidant activity of black rice bran of different commercially available varietiesMing Wei Zhang
Department of Food Science, Cornell University, Ithaca, New York 14853 7201, USA
J Agric Food Chem 58:7580-7. 2010..Knowing the phytochemical profile and antioxidant activity of black rice bran gives insights to its potential application to promote health...
Effect of processing on the phytochemical profiles and antioxidant activity of corn for production of masa, tortillas, and tortilla chipsColumba De La Parra
Department of Food Science, Cornell University, Ithaca, New York 14853 7201, USA
J Agric Food Chem 55:4177-83. 2007..These findings suggest that lime-cooking significantly reduced the phytochemical content of nixtamalized products but released phenolics and ferulic acid...
Phytochemicals and antioxidant activity of milled fractions of different wheat varietiesKafui Kwami Adom
Department of Food Science, Cornell University, Ithaca, New York 14853-7201, USA
J Agric Food Chem 53:2297-306. 2005..These findings provide information necessary for evaluating contributions to good health and disease prevention from whole-wheat consumption...
Thermal processing enhances the nutritional value of tomatoes by increasing total antioxidant activityVeronica Dewanto
Department of Food Science and Institute of Comparative and Environmental Toxicology, Stocking Hall, Cornell University, Ithaca, New York 14853, USA
J Agric Food Chem 50:3010-4. 2002..This information may have a significant impact on consumers' food selection by increasing their consumption of fruits and vegetables to reduce the risks of chronic diseases...
Rapid peroxyl radical scavenging capacity (PSC) assay for assessing both hydrophilic and lipophilic antioxidantsKafui Kwami Adom
Department of Food Science, Cornell University, Ithaca, New York 14853-7201, USA
J Agric Food Chem 53:6572-80. 2005..The PSC assay can be routinely used to analyze or screen both hydrophilic and lipophilic antioxidants or food extracts and will be a valuable alternative biomarker for future epidemiological studies of chronic diseases...
Health benefits of whole grain phytochemicalsNeal Okarter
Department of Food Science, Cornell University, Ithaca, NY 14853 7201, USA
Crit Rev Food Sci Nutr 50:193-208. 2010..In this paper, whole grain phytochemicals and the health benefits associated with their consumption are reviewed...
Cranberries inhibit LDL oxidation and induce LDL receptor expression in hepatocytesYi-Fang Chu
Department of Food Science, Stocking Hall, Cornell University, Ithaca, NY 14853-7201, United States
Life Sci 77:1892-901. 2005..We propose that additive or synergistic effects of phytochemicals in cranberries are responsible for the inhibition of LDL oxidation, the induced expression of LDL receptors, and the increased uptake of cholesterol in hepatocytes...
Antioxidant activity of processed table beets (Beta vulgaris var, conditiva) and green beans (Phaseolus vulgaris L.)Thudnatkorn Jiratanan
Department of Food Science and Institute of Comparative and Environmental Toxicology, Stocking Hall, Cornell University, Ithaca, New York 14853, USA
J Agric Food Chem 52:2659-70. 2004..It also reinforces the concept that optimal health benefits may be achieved when a wide variety of plant foods (fruits, vegetables and whole grains) and preparation methods are incorporated into the diet...
Controlled-atmosphere effects on postharvest quality and antioxidant activity of cranberry fruitsGurbuz Gunes
Department of Food Engineering, Istanbul Technical University, Istanbul, Turkey
J Agric Food Chem 50:5932-8. 2002..However, the total antioxidant activity of the fruits increased overall by about 45% in fruits stored in air. This increase was prevented by storage in 30% CO(2) plus 21% O(2)...
Research Grants
- Antiviral/Antitumor Roles of Ganoderma Lucidum SporesRui Liu; Fiscal Year: 2005....
