Research Topics
Species | Zhenglong GuSummaryAffiliation: Cornell University Country: USA Publications
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Detail Information
Publications
Yeasts as models in evolutionary biologyZhenglong Gu
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
Genome Biol 10:304. 2009..A report of the workshop 'Evolutionary and Environmental Genomics of Yeasts', Heidelberg, Germany, 1-5 October 2008...
Tinkering evolution of post-transcriptional RNA regulons: puf3p in fungi as an exampleHuifeng Jiang
Division of Nutritional Sciences, Cornell University, Ithaca, New York, United States of America
PLoS Genet 6:e1001030. 2010..Our results provide a scenario for how evolution like a tinker exploits pre-existing materials of a conserved post-transcriptional regulon to regulate gene expression for novel functional roles...
Differential selection on gene translation efficiency between the filamentous fungus Ashbya gossypii and yeastsHuifeng Jiang
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
BMC Evol Biol 8:343. 2008..Codon usage patterns were compared to identify orthologous genes with different gene regulation between A. gossypii and nine closely related yeast species...
Growth of novel epistatic interactions by gene duplicationHuifeng Jiang
Division of Nutritional Sciences, Cornell University, Ithaca, New York, USA
Genome Biol Evol 3:295-301. 2011..Furthermore, duplicate gene pairs tend to epistatically interact with genes that occupy more functional spaces than do single-copy genes. These results show that gene duplication plays an important role in the evolution of epistasis...
Genetic architecture of growth traits revealed by global epistatic interactionsLin Xu
Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York
Genome Biol Evol 3:909-14. 2011..Our results provide a genome-wide perspective on the genetic architecture of growth traits in a eukaryotic organism...
Recent advances in understanding the role of nutrition in human genome evolutionKaixiong Ye
Division of Nutritional Sciences, Cornell University, Ithaca, NY
Adv Nutr 2:486-96. 2011..Understanding the role of diet in human evolution is fundamental for the development of evidence-based, genome-informed nutritional practices in the era of personal genomics...
Relaxation of yeast mitochondrial functions after whole-genome duplicationHuifeng Jiang
Division of Nutritional Sciences, Cornell University, Ithaca, New York 14853, USA
Genome Res 18:1466-71. 2008..This new energy production strategy could have led to the relaxation of mitochondrial function in the relevant yeast species...
Detection of heterozygous mutations in the genome of mismatch repair defective diploid yeast using a Bayesian approachSarah Zanders
Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA
Genetics 186:493-503. 2010..In addition, they demonstrate that the mutation pattern seen previously in mismatch repair defective strains using a limited number of reporters holds true for the entire genome...
A conserved structural determinant located at the interdomain region of mammalian inositol-requiring enzyme 1alphaZhen Xue
Graduate Program in Nutrition, Cornell University, Ithaca, New York 14853, USA
J Biol Chem 286:30859-66. 2011..Our finding may facilitate the identification of small molecules to compromise IRE1? function specifically...
