Lora Hedrick EllensonSummaryAffiliation: Cornell University Country: USA Publications
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Focus on endometrial and cervical cancerLora Hedrick Ellenson
Department of Pathology, The Weill Medical College of Cornell University, New York, NY 10021, USA
Cancer Cell 5:533-8. 2004- DNA mismatch repair deficiency accelerates endometrial tumorigenesis in Pten heterozygous miceHong Wang
Department of Pathology, Weill Medical Collegeof Cornell University, New York
Am J Pathol 160:1481-6. 2002.... - Beta-catenin and E-cadherin expression patterns in high-grade endometrial carcinoma are associated with histological subtypePeter W Schlosshauer
Department of Pathology, Weill Medical College of Cornell University, New York, New York, USA
Mod Pathol 15:1032-7. 2002..Notably, differences in cell adhesion molecule expression could account for variations in patterns of tumor dissemination. The immunohistochemical staining pattern may also be useful for diagnostic purposes... - Molecular genetic characterization of tamoxifen-associated endometrial cancerMonica Prasad
Division of Gynecologic Pathology, Department of Pathology, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, USA
Gynecol Oncol 96:25-31. 2005..CONCLUSION: Tamoxifen and non-tamoxifen-associated endometrial carcinomas arising in women with breast cancer contain similar genetic alterations to those of sporadic endometrial carcinomas... - Histologic type, organ of origin, and Wnt pathway status: effect on gene expression in ovarian and uterine carcinomasKerby A Shedden
Department of Statistics, Medical School, University of Michigan, Ann Arbor, MI 48109, USA
Clin Cancer Res 11:2123-31. 2005..The findings also imply gene expression data will be of value for stratifying ovarian cancer patients for new treatment approaches... - Akt-mediated phosphorylation and activation of estrogen receptor alpha is required for endometrial neoplastic transformation in Pten+/- miceAnna Vilgelm
Human Genetics Program and Department of Pathology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
Cancer Res 66:3375-80. 2006..Thus, we provide for the first time in vivo evidence supporting the hypothesis that loss of Pten and subsequent Akt activation result in the activation of ERalpha-dependent pathways that play a pivotal role in the neoplastic process... - PIK3CA and PTEN mutations in uterine endometrioid carcinoma and complex atypical hyperplasiaMonica Prasad Hayes
Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, NY 10021, USA
Clin Cancer Res 12:5932-5. 2006..PTEN mutations are also common in complex atypical hyperplasia (CAH), the precursor lesion of UEC. The status of PIK3CA has not yet been explored in CAH. In this study, we evaluated both CAH and UEC for PTEN and PIK3CA mutations... - The high-mobility group A1 gene up-regulates cyclooxygenase 2 expression in uterine tumorigenesisAbeba Tesfaye
Hematology Division, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Cancer Res 67:3998-4004. 2007..Although a larger study is needed to confirm these results, HMGA1a may be a useful marker for aggressive human uterine cancers... - Endometrial carcinomaAntonio Di Cristofano
Human Genetics Program, Division of Population Science, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
Annu Rev Pathol 2:57-85. 2007....