Research Topics
Species | G WenSummaryAffiliation: Columbia University Country: USA Publications
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Detail Information
Publications
Neoplastic transformation of human small airway epithelial cells induced by arsenicGengyun Wen
Center for Radiological Research, Columbia University Medical Center, New York, NY 10032, USA
Mol Med 14:2-10. 2008..Taken together, these results strongly suggest that h-TERT immortalized human small airway epithelial cells underwent step-wise transformation after inorganic arsenic treatment...
Increased susceptibility of human small airway epithelial cells to apoptosis after long term arsenate treatmentGengyun Wen
Center for Radiological Research, Columbia University Medical Center, New York, NY 10032, United States
Sci Total Environ 407:1174-81. 2009..To confirm the involvement of p38 in the regulation of apoptosis we pretreated cells with the p38 kinase inhibitor, SB 203580 and observed a significant decrease in apoptosis...
Phosphoproteomic profiling of arsenite-treated human small airway epithelial cellsG Wen
Centre for Radiological Research, Columbia University, New York, NY 10032, USA
Oncol Rep 23:405-12. 2010..It can be concluded that analysis of phosphoprotein by using phosphoproteomic profiling can be very useful to understand the mechanism of arsenite-induced carcinogenesis...
TGFBI expression reduces in vitro and in vivo metastatic potential of lung and breast tumor cellsGengyun Wen
Center for Radiological Research, College of Physicians and Surgeons, Columbia University, New York, NY, USA
Cancer Lett 308:23-32. 2011..Taken together, these data suggest that TGFBI moderates the metastatic potential of cancer cells...
