Research Topics
Species | N ScarmeasSummaryAffiliation: Columbia University Country: USA Publications
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Publications
Mediterranean diet and risk for Alzheimer's diseaseNikolaos Scarmeas
Taub Institute for Research in Alzheimer s Disease and the Aging Brain, New York, NY 10032, USA
Ann Neurol 59:912-21. 2006..We sought to investigate the association between MeDi and risk for AD...- Mediterranean diet and Alzheimer disease mortalityNikolaos Scarmeas
Taub Institute for Research in Alzheimer s Disease and the Aging Brain, Columbia University Medical Center, New York, NY 10032, USA
Neurology 69:1084-93. 2007..We previously reported that the Mediterranean diet (MeDi) is related to lower risk for Alzheimer disease (AD). Whether MeDi is associated with subsequent AD course and outcomes has not been investigated... - APOE-dependent PET patterns of brain activation in Alzheimer diseaseN Scarmeas
Cognitive Neuroscience Division of the Taub Institute for Research in Alzheimer s Disease and the Aging Brain, College of Physicians and Surgeons of Columbia University New York, NY 10032, USA
Neurology 63:913-5. 2004..The APOE genotype seems to play a role in cerebral physiologic activity even after onset of clinical manifestations of AD... - Motor signs during the course of Alzheimer diseaseN Scarmeas
Cognitive Neuroscience Division, Taub Institute for Research in Alzheimer s Disease and the Aging Brain, Gertrude H Sergievsky Center, and Department of Neurology, New York, NY 10032, USA
Neurology 63:975-82. 2004..Motor signs (MOSIs) are common in Alzheimer disease (AD) and may be associated with rates of cognitive decline, mortality, and cost of care... - Mediterranean diet, Alzheimer disease, and vascular mediationNikolaos Scarmeas
Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University Medical Center, New York, NY 10032, USA
Arch Neurol 63:1709-17. 2006..To examine the association between the Mediterranean diet (MeDi) and Alzheimer disease (AD) in a different AD population and to investigate possible mediation by vascular pathways. Design, Setting, Patients, and.. - Seizures in Alzheimer disease: who, when, and how common?Nikolaos Scarmeas
Department of Neurology, Columbia University Medical Center, 622 W 168 St, PH Bldg, 19th Floor, New York, NY 10032, USA
Arch Neurol 66:992-7. 2009..The incidence of seizures in AD and predictors of which patients with AD might be more predisposed to them is based primarily on retrospective studies and is not well established... - Mediterranean diet and mild cognitive impairmentNikolaos Scarmeas
Department of Neurology, Columbia University Medical Center, New York, NY 10032, USA
Arch Neurol 66:216-25. 2009..Higher adherence to the Mediterranean diet (MeDi) may protect from Alzheimer disease (AD), but its association with mild cognitive impairment (MCI) has not been explored... - Motor signs predict poor outcomes in Alzheimer diseaseN Scarmeas
Cognitive Neuroscience Division of the Taub Institute for Research in Alzheimer s Disease and the Aging Brain, Columbia University Medical Center, New York, NY 10032, USA
Neurology 64:1696-703. 2005..To examine whether the presence of motor signs has predictive value for important outcomes in Alzheimer disease (AD)... - Invited commentary: lipoproteins and dementia - is it the apolipoprotein A-I?Nikolaos Scarmeas
Taub Institute for Research in Alzheimer s Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
Am J Epidemiol 165:993-7. 2007..In this commentary, the epidemiology and biology of apolipoprotein A-I in relation to dementia is reviewed... - APOE related alterations in cerebral activation even at college ageN Scarmeas
Cognitive Neuroscience Division of the Taub Institute for Research in Alzheimer s Disease and the Aging Brain, Columbia University Medical Center, New York, NY 10032, USA
J Neurol Neurosurg Psychiatry 76:1440-4. 2005..The association between the APOE genotype and cognitive performance varies at different ages. APOE related changes in brain activation have been recently reported for middle aged and elderly subjects... - Delusions and hallucinations are associated with worse outcome in Alzheimer diseaseNikolaos Scarmeas
Cognitive Neuroscience Division of the Taub Institute for Research on Alzheimer s Disease and the Aging Brain, The Gertrude H Sergievsky Center, New York, NY 10032, USA
Arch Neurol 62:1601-8. 2005..According to all previous literature, they are not associated with mortality... - Education and rates of cognitive decline in incident Alzheimer's diseaseN Scarmeas
Cognitive Neuroscience Division, Taub Institute for Research in Alzheimer s Disease and the Aging Brain, Columbia University Medical Center, 622 West 168th Street, PH 19th Floor, New York, NY 10032, USA
J Neurol Neurosurg Psychiatry 77:308-16. 2006..We wanted to assess the relationship between education and rates of decline in AD... - Imaging studies and APOE genotype in persons at risk for Alzheimer's diseaseNikolaos Scarmeas
Columbia University Medical Center, 622 West 168th Street, PH 19th Floor, New York, NY 10032, USA
Curr Psychiatry Rep 8:11-7. 2006..APOE-related findings in imaging studies of nondemented subjects may be the result of incipient AD pathologic changes or of genetic heterogeneity in brain structure and function... - Disruptive behavior as a predictor in Alzheimer diseaseNikolaos Scarmeas
Gertrude H Sergievsky Center, Columbia University Medical Center, New York, NY 10032, USA
Arch Neurol 64:1755-61. 2007..Disruptive behavior is common in Alzheimer disease (AD). There are conflicting reports regarding its ability to predict cognitive decline, functional decline, institutionalization, and mortality... - Covariance PET patterns in early Alzheimer's disease and subjects with cognitive impairment but no dementia: utility in group discrimination and correlations with functional performanceNikolaos Scarmeas
Cognitive Neuroscience Division of the Taub Institute for Research on Alzheimer s Disease and the Aging Brain, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
Neuroimage 23:35-45. 2004..Expression of covariance patterns correlates with cognitive and functional performance measures, holding promise for meaningful associations with underlying biopathological processes... - Cognitive reserve: implications for diagnosis and prevention of Alzheimer's diseaseNikolaos Scarmeas
Columbia Presbyterian Medical Center, 622 West 168th Street, PH 19th Floor, New York, NY 10032, USA
Curr Neurol Neurosci Rep 4:374-80. 2004..In this article, we review some of the relevant literature of the noted associations between markers of cognitive reserve and AD and discuss the possible mechanisms that may explain these associations... - Mediterranean diet and magnetic resonance imaging-assessed cerebrovascular diseaseNikolaos Scarmeas
Taub Institute for Research in Alzheimer s Disease and the Aging Brain, University of California at Davis, Sacramento, USA
Ann Neurol 69:257-68. 2011..Cerebrovascular disease is 1 of the possible mechanisms of the previously reported relationship between Mediterranean-type diet (MeDi) and Alzheimer's disease (AD). We sought to investigate the association between MeDi and MRI infarcts... - Physical activity and Alzheimer disease courseNikolaos Scarmeas
Taub Institute for Research in Alzheimer s Disease and the Aging Brain, Columbia University Medical Center, NY 10032, USA
Am J Geriatr Psychiatry 19:471-81. 2011..To examine the association between physical activity (PA) and Alzheimer disease (AD) course... - Altered PET functional brain responses in cognitively intact elderly persons at risk for Alzheimer disease (carriers of the epsilon4 allele)Nikolaos Scarmeas
Departments of Neurology, College of Physicians and Surgeons of Columbia University Medical Center 622 West 168th St, PH 19th floor New York, NY 10032, USA
Am J Geriatr Psychiatry 12:596-605. 2004..The authors investigated APOE-mediated differential brain activation in a group of healthy elderly subjects... - Association of life activities with cerebral blood flow in Alzheimer disease: implications for the cognitive reserve hypothesisNikolaos Scarmeas
Cognitive Neuroscience Division of the Taub Institute for Research in Alzheimer s Disease and the Aging Brain, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
Arch Neurol 60:359-65. 2003..This has been interpreted as suggesting that cognitive reserve allows these patients to cope better with the pathologic changes in AD... - Cognitive reserve and lifestyleNikolaos Scarmeas
Cognitive Neuroscience Division, Department of Neurology, Taub Institute for Research in Alzheimer s Disease and the Aging Brain, and College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
J Clin Exp Neuropsychol 25:625-33. 2003..It is possible that aspects of life experience like engagement in leisure activities may result in functionally more efficient cognitive networks and therefore provide a CR that delays the onset of clinical manifestations of dementia... - Cortical basal ganglionic degenerationN Scarmeas
College of Physicians and Surgeons of Columbia University, New York Presbyterian Hospital, Department of Neurology, Taub Institute for Research on Alzheimer s Disease and the Aging Brain, the Sergievsky Center, New York, NY 12345, USA
Sci Aging Knowledge Environ 2001:dn1. 2001..CBGD is characterized by Parkinson's-like motor symptoms and by deficits of movement and cognition, indicating focal brain pathology. Neuronal cell loss is ultimately responsible for the neurological symptoms... - Physical activity, diet, and risk of Alzheimer diseaseNikolaos Scarmeas
Taub Institute for Research in Alzheimer s Disease and the Aging Brain and Department of Neurology, Columbia University Medical Center, 622 W 168th St, New York, NY 10032, USA
JAMA 302:627-37. 2009..Both higher adherence to a Mediterranean-type diet and more physical activity have been independently associated with lower Alzheimer disease (AD) risk but their combined association has not been investigated... - Cognitive reserve-mediated modulation of positron emission tomographic activations during memory tasks in Alzheimer diseaseNikolaos Scarmeas
Cognitive Neuroscience Division, Taub Institute for Research on Alzheimer s Disease and the Aging Brain, College of Physicians and Surgeons of Columbia University, New York, NY, USA
Arch Neurol 61:73-8. 2004..Epidemiological data and evidence from positron emission tomography suggest that it may be mediated through education or IQ... - Impairment of nonverbal recognition in Alzheimer disease: a PET O-15 studyK E Anderson
Cognitive Neuroscience Division, Taub Institute for Alzheimer s Disease and the Aging Brain, College of Physicians and Surgeons of Columbia University, New York, NY, USA
Neurology 69:32-41. 2007..To characterize deficits in nonverbal recognition memory and functional brain changes associated with these deficits in Alzheimer disease (AD)... - APOE epsilon 4 allele predicts faster cognitive decline in mild Alzheimer diseaseS Cosentino
Cognitive Neuroscience Division of the Gertrude H Sergievsky Center, Columbia University Medical Center, New York, NY 10032, USA
Neurology 70:1842-9. 2008..To determine whether APOE epsilon 4 predicts rate of cognitive change in incident and prevalent Alzheimer disease (AD)... - Association between the APOE genotype and psychopathologic symptoms in Alzheimer's diseaseN Scarmeas
Cognitive Neuroscience Division, Taub Institute for Research in Alzheimer s Disease and the Aging Brain, New York, NY, USA
Neurology 58:1182-8. 2002..Previous studies investigating the association between APOE genotype and psychiatric symptomatology in AD have reported contradictory results... - Patient dependence and longitudinal changes in costs of care in Alzheimer's diseaseCarolyn W Zhu
Geriatric Research, Education, and Clinical Center GRECC, James J Peters VA Medical Center, Bronx, NY, NY 10468, USA
Dement Geriatr Cogn Disord 26:416-23. 2008..To examine the incremental effect of patients' dependence on others, on cost of medical and nonmedical care, and on informal caregiving hours over time... - Influence of leisure activity on the incidence of Alzheimer's diseaseN Scarmeas
Cognitive Neuroscience Division of the Gertrude H. Sergievsky Center, Columbia University College of Physicians and Surgeons, New York, NY, USA
Neurology 57:2236-42. 2001..CONCLUSIONS: The data suggest that engagement in leisure activities may reduce the risk of incident dementia, possibly by providing a reserve that delays the onset of clinical manifestations of the disease... - Survival in Alzheimer disease: a multiethnic, population-based study of incident casesE P Helzner
Gertrude H Sergievsky Center, Columbia University Medical Center, New York, NY 10032, USA
Neurology 71:1489-95. 2008..To describe factors associated with survival in Alzheimer disease (AD) in a multiethnic, population-based longitudinal study... - Contribution of vascular risk factors to the progression in Alzheimer diseaseElizabeth P Helzner
Gertrude H Sergievsky Center, Columbia University Medical Center, NY, New York, USA
Arch Neurol 66:343-8. 2009.... - Food combination and Alzheimer disease risk: a protective dietYian Gu
The Taub Institute for Research in Alzheimer s Disease and the Aging Brain, Columbia University, New York, NY, USA
Arch Neurol 67:699-706. 2010..Because foods are not consumed in isolation, dietary pattern (DP) analysis of food combination, taking into account the interactions among food components, may offer methodological advantages... - Mediterranean diet and essential tremor. A case-control studyNikolaos Scarmeas
Taub Institute for Research in Alzheimer s Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
Neuroepidemiology 29:170-7. 2007..Higher adherence to the Mediterranean diet (MeDi) has been related to lower Alzheimer's disease risk. Some dietary factors have been studied in patients with essential tremor (ET), but the MeDi's effect has not been investigated... - Cognitive reserve modulates functional brain responses during memory tasks: a PET study in healthy young and elderly subjectsNikolaos Scarmeas
Cognitive Neuroscience Division of the Taub Institute for Research in Alzheimer's Disease and the Aging Brain, New York, NY 10032, USA
Neuroimage 19:1215-27. 2003..Brain regions where systematic relationships between CR and brain activation differ as a function of aging are loci where compensation for aging has occurred. They may mediate differential ability to cope with brain changes in aging... - Verbal fluency predicts mortality in Alzheimer diseaseStephanie Cosentino
Cognitive Neuroscience Division, Taub Institute for Research in Alzheimer's Disease and the Aging Brain, NY, USA
Cogn Behav Neurol 19:123-9. 2006..The prognostic value of these tests may derive from their general psychometric properties, or may reflect the measures' sensitivity to an early or critical level of compromise to frontal networks... - Depressive symptoms in Alzheimer's disease: natural course and temporal relation to function and cognitive statusRoee Holtzer
Cognitive Neuroscience Division, Taub Institute, G.H. Gertrude Sergievsky Center and Department of Neurology, College of Physicians and Surgeons, Columbia University Medical Center, New York, New York 10032, USA
J Am Geriatr Soc 53:2083-9. 2005..Examination of the temporal relationship between depressive symptoms and risk factors suggests that decline in function but not in cognition precedes the first episode of depressive symptoms in patients with probable AD... - An observational study of cognitive impairment in amyotrophic lateral sclerosisGregory A Rippon
Department of Neurology, Gertrude H. Sergievsky Center, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Eleanor and Lou Gehrig MDA/ALS Research Center, New York, NY, USA
Arch Neurol 63:345-52. 2006..CONCLUSIONS: Nearly a third of the patients with ALS showed evidence of cognitive impairment in a pattern consistent with frontotemporal lobar dementia. Cognitive performance was not related to site of onset or survival... - Identification and differential vulnerability of a neural network in sleep deprivationSandra Bell-McGinty
Cognitive Neuroscience Division of the Taub Institute for Research in Alzheimer's Disease and the Aging Brain, 630 West 168th Street, PH-18, New York, USA
Cereb Cortex 14:496-502. 2004..A network whose expression decreased after sleep deprivation and correlated with memory performance was identified. We conclude that this activation network plays a role in cognitive function during sleep deprivation... - Periodontitis is associated with cognitive impairment among older adults: analysis of NHANES-IIIJ M Noble
Gertrude H Sergievsky Center, Columbia University Medical Center, New York, NY, USA
J Neurol Neurosurg Psychiatry 80:1206-11. 2009..Dementia is a major public health problem likely related to a complex interaction between genetics and diseases associated with systemic inflammation, including diabetes, smoking and stroke... - Clinical trial of an air-circulating cooling blanket for fever control in critically ill neurologic patientsS Mayer
Division of Critical Care Neurology, Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA
Neurology 56:292-8. 2001..To evaluate the efficacy of an air-circulating cooling blanket for reducing body temperature in febrile neuro-ICU patients treated with acetaminophen... - A forward application of age associated gray and white matter networksAdam M Brickman
Cognitive Neuroscience Division, Taub Institute for Research on Alzheimer s Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
Hum Brain Mapp 29:1139-46. 2008..405, P = 0.024). The findings suggest that the previously derived age-associated covariance pattern for gray matter is reliable and may provide information that is more functionally meaningful than chronological age... - Multivariate and univariate analysis of continuous arterial spin labeling perfusion MRI in Alzheimer's diseaseIris Asllani
Department of Radiology, Columbia University, New York, New York 10032, USA
J Cereb Blood Flow Metab 28:725-36. 2008..When tested on extensive split-half analysis to map out the replicability of both multivariate and univariate approaches, the expression of the pattern from multivariate analysis was superior to that of the univariate... - Measuring cerebral atrophy and white matter hyperintensity burden to predict the rate of cognitive decline in Alzheimer diseaseAdam M Brickman
Taub Institute for Research on Alzheimer s Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, 630 W 168th St, Campus Box 16, New York, NY 10032, USA
Arch Neurol 65:1202-8. 2008..To determine if baseline measurements of cerebral atrophy and severity of white matter hyperintensity (WMH) predict the rate of future cognitive decline in patients with Alzheimer disease (AD)... - Leisure activity and cognitive decline in incident Alzheimer diseaseElizabeth P Helzner
Gertrude H Sergievsky Center, Columbia University Medical Center, New York, NY 10032, USA
Arch Neurol 64:1749-54. 2007..High rates of leisure activity have been associated with reduced risk of Alzheimer disease (AD)... - Randomized double-blind placebo-controlled donepezil augmentation in antidepressant-treated elderly patients with depression and cognitive impairment: a pilot studyGregory H Pelton
Late Life Depression Clinic, The Memory Disorders Center, and The Division of Geriatric Psychiatry, New York State Psychiatric Institute, NY, USA
Int J Geriatr Psychiatry 23:670-6. 2008..To assess combined antidepressant and cognitive enhancer treatment in elderly patients presenting with depression plus cognitive impairment... - Plasma ß-amyloid and cognitive declineStephanie A Cosentino
The Gertrude H Sergievsky Center, Taub Institute for Research in Alzheimer s Disease and the Aging Brain, Columbia University Medical Center, New York, NY 10032, USA
Arch Neurol 67:1485-90. 2010..To determine if plasma ?-amyloid (A?) levels (1) can be linked to specific cognitive changes that constitute conversion to Alzheimer disease (AD) and (2) correspond to cognitive change independent of dementia... - Diet and Alzheimer's diseaseJose A Luchsinger
Taub Institute for Research of Alzheimer s Disease and the Aging Brain, Columbia University, PH9E 105, 630 West 168th Street, New York, NY 10032, USA
Curr Neurol Neurosci Rep 7:366-72. 2007..The existing evidence does not support the recommendation of specific supplements, foods, or diets for the prevention of AD... - Predictive utility of apolipoprotein E genotype for Alzheimer disease in outpatients with mild cognitive impairmentD P Devanand
Department of Biological Psychiatry, New York State Psychiatric Institute, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
Arch Neurol 62:975-80. 2005..In cognitively impaired patients without dementia, the utility of apolipoprotein E (APOE) genotyping is unclear... - An event-related fMRI study of the neural networks underlying the encoding, maintenance, and retrieval phase in a delayed-match-to-sample taskChristian Habeck
Cognitive Neuroscience Division of the Taub Institute for Research in Alzheimer s Disease and the Aging Brain, 622 West 168th Street, PH 18, New York, NY 10032, USA
Brain Res Cogn Brain Res 23:207-20. 2005..The load-related activation patterns from encoding and retrieval phase and their relationship to behavior are also discussed... - Single-dose levodopa administration and aging independently disrupt time productionBrian C Rakitin
Columbia University, New York, NY 10032, USA
J Cogn Neurosci 18:376-87. 2006..Moreover, the levodopa timing effect cannot be attributed to the effects of dopaminergic function on psychomotor speed... - PET network abnormalities and cognitive decline in patients with mild cognitive impairmentDavangere P Devanand
Department of Biological Psychiatry, College of Physicians and Surgeons, New York State Psychiatric Institute, Columbia University, New York, NY 10032, USA
Neuropsychopharmacology 31:1327-34. 2006..Independent replication in larger samples is needed before clinical application can be considered... - The progression of cognition, psychiatric symptoms, and functional abilities in dementia with Lewy bodies and Alzheimer diseaseKarina Stavitsky
Gertrude H. Sergievsky Center and Department of Neurology, Columbia University Medical Center, New York, NY, USA
Arch Neurol 63:1450-6. 2006..CONCLUSIONS: Both baseline and longitudinal differences between patients with DLB and patients with AD were noted; these have implications for clinical diagnosis and treatment... - Brain networks associated with cognitive reserve in healthy young and old adultsYaakov Stern
Cognitive Neuroscience Division, Taub Institute, College of Physicians and Surgeons, Columbia University, New York, USA
Cereb Cortex 15:394-402. 2005..Thus, for the old subjects this topography may represent an altered, compensatory network that is used to maintain function in the face of age-related physiological changes... - A randomized, double-blind, placebo-controlled trial of donepezil to improve memory in epilepsyMarla J Hamberger
Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York, USA
Epilepsia 48:1283-91. 2007..To determine whether an acetylcholinesterase inhibitor, such as donepezil, would improve memory or other cognitive/psychological functions in epilepsy patients with subjective memory complaints... - Distinct pools of beta-amyloid in Alzheimer disease-affected brain: a clinicopathologic studyJoshua R Steinerman
Departments of Neurology, Columbia University Medical Center, 630 W 168th St, P and S Box 16, New York, NY 10032, USA
Arch Neurol 65:906-12. 2008..To determine whether beta-amyloid (Abeta) peptides segregated into distinct biochemical compartments would differentially correlate with clinical severity of Alzheimer disease (AD)... - Dietary patterns in Alzheimer's disease and cognitive agingY Gu
The Taub Institute for Research in Alzheimer s Disease and the Aging Brain, Columbia University, New York, NY 10032, USA
Curr Alzheimer Res 8:510-9. 2011..Further studies are warranted, though, to confirm the findings in different population settings, to address some methodological issues, and possibly utilize the information for future clinical trial design... - Risk factors for fever in the neurologic intensive care unitChristopher Commichau
Division of Critical Care Neurology, Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA
Neurology 60:837-41. 2003..Subarachnoid hemorrhage increases the risk of developing fever of all types... - An event-related fMRI study of the neurobehavioral impact of sleep deprivation on performance of a delayed-match-to-sample taskChristian Habeck
Cognitive Neuroscience Division of the Taub Institute for Research in Alzheimer's Disease and the Aging Brain, 630 West 168th Street, PH-18, New York, NY 10032, USA
Brain Res Cogn Brain Res 18:306-21. 2004..Subject decreases in pattern expression were correlated with reductions in recognition accuracy (p<0.05), increased intra-individual variability in reaction time (p<0.005) and increased lapsing (p<0.005)... - Application of pet imaging to diagnosis of Alzheimer's disease and mild cognitive impairmentJames M Noble
Department of Neurology, Harlem Hospital Center, Columbia University College of Physicians and Surgeons, New York 10037, USA
Int Rev Neurobiol 84:133-49. 2009..From this we advise scenarios for use of PET in primary settings and referral centers, approach to its interpretation, and outline a clinical prediction model based on findings... - Premorbid weight, body mass, and varsity athletics in ALSN Scarmeas
Department of Neurology, Neurological Institute of Columbia-Presbyterian Medical Center, New York, NY 10032, USA
Neurology 59:773-5. 2002..For slimness, the odds ratio (OR) was 2.21; 95% CI, 1.40 to 3.47. For varsity athletics, the OR was 1.70; CI, 1.04 to 2.76... - Comparison of costs of care between patients with Alzheimer's disease and dementia with Lewy bodiesCarolyn W Zhu
Geriatric Research, Education, and Clinical Center and Program of Research on Serious Physical and Mental Illness, Targeted Research Enhancement Program, James J Peters VA Medical Center, Bronx, NY, USA
Alzheimers Dement 4:280-4. 2008..This cross-sectional analysis of baseline data from the Predictors II Study took place in three university-based AD centers in the U.S... - The relation of patient dependence to home health aide use in Alzheimer's diseaseRachel K Scherer
Cognitive Neuroscience Division, Taub Institute for Research in Alzheimer s Disease and the Aging Brain, Gertrude H Sergievsky Center, Department of Neurology, Columbia University Medical Center, 630 West 168th St, P and S Box 16, New York, NY 10032, USA
J Gerontol A Biol Sci Med Sci 63:1005-9. 2008..The objective of this study was to examine whether the Dependence Scale can predict home health aide (HHA) use... - Home health and informal care utilization and costs over time in Alzheimer's diseaseCarolyn W Zhu
Geriatric Research, Education, and Clinical Center GRECC, James J Peters VA Medical Center, Bronx, NY 10468, USA
Home Health Care Serv Q 27:1-20. 2008.... - The effects of patient function and dependence on costs of care in Alzheimer's diseaseCarolyn W Zhu
Geriatric Research, Education, and Clinical Center, Program of Research on Serious Physical and Mental Illness, James J Peters Veterans Affairs Medical Center, Bronx, New York 10468, USA
J Am Geriatr Soc 56:1497-503. 2008..To estimate incremental effects of patients' dependence and function on costs of care during the early stages of Alzheimer's disease (AD) and to compare strengths of their relationships with different cost components... - fMRI evidence of compensatory mechanisms in older adults at genetic risk for Alzheimer diseaseNikolaos Scarmeas
Neurology 65:1514-5; author reply 1514-5. 2005 - APOE genotype and cerebral blood flow in healthy young individualsNikolaos Scarmeas
JAMA 290:1581-2. 2003 - Most cases of dementia with hippocampal sclerosis may represent frontotemporal dementiaLawrence S Honig
Neurology 64:1102; author reply 1102. 2005 - Paraoxonase 1 gene polymorphisms in patients with osteonecrosis of the femoral head with and without cerebral white matter lesionsGeorgios M Hadjigeorgiou
Neurogenetics Unit, Department of Neurology, School of Medicine, University of Thessaly, Larissa 41222, Greece
J Orthop Res 25:1087-93. 2007..43; 95%CI = 1.04-1.97; p for trend = 0.03). We conclude that individuals with PON1 192QQ genotype may have increased risk for ONFH and WMLeOn... - Association of alpha-synuclein Rep1 polymorphism and Parkinson's disease: influence of Rep1 on age at onsetGeorgios M Hadjigeorgiou
Neurogenetics Unit, Department of Neurology, Medical School, University of Thessaly, Larissa, Greece
Mov Disord 21:534-9. 2006..For Rep1 allele 1, there was neither association with risk of PD nor influence on age at onset. This is the first study showing an influence of Rep1 polymorphism on age at onset of PD... - Clinical characteristics and longitudinal changes of informal cost of Alzheimer's disease in the communityCarolyn W Zhu
Geriatric Research, Education, and Clinical Center and Program of Research on Serious Physical and Mental Illness, James J Peters Department of Veterans Affairs Medical Center, Bronx, New York 10468, USA
J Am Geriatr Soc 54:1596-602. 2006..Each additional point on the BDRS increased informal caregiving costs 5.4%. Average annual informal cost was estimated at $25,381 per patient, increasing from $20,589 at baseline to $43,030 in Year 4... - CA 19-9 levels predict results of staging laparoscopy in pancreatic cancerAndreas Karachristos
Department of Surgery, Temple University Hospital, Philadelphia, Pennsylvania, USA
J Gastrointest Surg 9:1286-92. 2005..On the contrary, patients with elevated CA 19-9 have an increased probability of metastatic disease, and these patients may benefit from diagnostic laparoscopy... - Mediterranean diet and mortality in a US populationNikolaos Scarmeas
Arch Intern Med 168:1823-4. 2008 - Patient's age modifies the impact of the proposed predictors of sustained virological response in chronic hepatitis C patients treated with PEG-interferon plus ribavirinIoannis S Elefsiniotis
Department of Internal Medicine, Hepatology Unit, Hippokration Hospital, Athens, Greece
Eur J Intern Med 19:266-70. 2008..000 IU/ml), chronic hepatitis C (CHC) patients treated under real-life conditions in Greece... - Serum beta2-microglobulin levels in hepatitis B e antigen-negative chronic hepatitis B patients under long term lamivudine monotherapy: relationship with virological breakthroughIoannis S Elefsiniotis
Department of Hepatogastroenterology, University of Athens, Helena Venizelou Hospital, Athens, Greece
Can J Gastroenterol 18:307-13. 2004..To evaluate the predictive value of serum beta2-microglobulin (beta2m) levels for virological breakthrough in hepatitis B e antigen-negative chronic hepatitis B patients under long term lamivudine monotherapy...
Research Grants
- Mediterranean Diet and Other Dietary Patterns in Alzheimer's DiseaseNikolaos Scarmeas; Fiscal Year: 2010....