Research Topics
| Leonardo PignataroSummaryAffiliation: Columbia University Country: USA Publications
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Publications
The regulation of neuronal gene expression by alcoholLeonardo Pignataro
Department of Anesthesiology and Department of Pharmacology, The College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, NY 10032, USA
Pharmacol Ther 124:324-35. 2009..In this review we will describe some of the most interesting cellular and microarray work in the field, and will outline specific examples of genes for which the mechanisms of regulation by alcohol are now somewhat understood...
Alcohol regulates gene expression in neurons via activation of heat shock factor 1Leonardo Pignataro
Department of Anesthesiology, Weill Cornell Medical College, New York, New York 10021, USA
J Neurosci 27:12957-66. 2007....
GABAA receptors in the thalamus: alpha4 subunit expression and alcohol sensitivityFan Jia
Department of Anesthesiology, Weill Medical College, Cornell University, New York, NY 10021, USA
Alcohol 41:177-85. 2007..Investigating the effects of alcohol on both synaptic and extrasynaptic GABAA-Rs in the thalamus should help us to understand the mechanisms underlying the interaction between alcohol and sleep...
An extrasynaptic GABAA receptor mediates tonic inhibition in thalamic VB neuronsFan Jia
CV Starr Laboratory for Molecular Neuropharmacology, Department of Anesthesiology, Weill Medical College, Cornell University, New York, NY 10021, USA
J Neurophysiol 94:4491-501. 2005..In view of the critical role of thalamic neurons in the generation of oscillatory activity associated with sleep, these receptors may represent a principal site of action for the novel hypnotic agent gaboxadol...
