Mikala EgebladSummaryAffiliation: Cold Spring Harbor Laboratory Country: USA Publications
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Tumors as organs: complex tissues that interface with the entire organismMikala Egeblad
Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
Dev Cell 18:884-901. 2010..Understanding the complex ways in which cancer cells interact with their surroundings, both locally in the tumor organ and systemically in the body as a whole, has implications for effective cancer prevention and therapy...- Dynamic interplay between the collagen scaffold and tumor evolutionMikala Egeblad
Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
Curr Opin Cell Biol 22:697-706. 2010..Here we discuss how abnormal expression, proteolysis and structure of these collagens influence cellular functions to elicit multiple effects on tumors, including proliferation, initiation, invasion, metastasis, and therapy response... - Imaging Tumor-Stroma Interactions during Chemotherapy Reveals Contributions of the Microenvironment to ResistanceElizabeth S Nakasone
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA Watson School of Biological Sciences, Cold Spring Harbor, NY 11724, USA
Cancer Cell 21:488-503. 2012..These data show that the microenvironment contributes critically to drug response via regulation of vascular permeability and innate immune cell infiltration. Thus, live imaging can be used to gain insights into drug responses in situ...