J S Yadav

..The availability of potent antiplatelet regimens, emboli prevention devices and nitinol stents will greatly expand the spectrum of carotid disease that can be safely treated with endovascular therapy...

..Angioplasty and stenting are becoming increasingly accepted techniques for the treatment of carotid stenosis. However, the optimal stent for carotid intervention is not known...

..Stenting with the use of an emboli-protection device is a less invasive revascularization strategy than endarterectomy in carotid-artery disease...

..Filter devices are the current mainstay and have high technical success rates. Slow flow through the filters can happen with large embolic burdens and should be treated with aspiration prior to filter retrieval...

..This adjunctive therapy with potent glycoprotein IIb/IIIa inhibition may help to reduce periprocedural adverse events in patients undergoing carotid stenting...

..Coronary stents appear to be well suited to treat atherosclerotic lesions of the vertebral artery...

..Furthermore, clopidogrel appears superior to ticlopidine. Thus, our findings lend support to the dual antiplatelet strategy of clopidogrel plus aspirin for patients undergoing carotid artery stenting...

..There were no procedural deaths, myocardial infarctions, or strokes. Thus, among carefully selected patients, simultaneous bilateral carotid artery stenting is a promising, technically feasible option...

..To evaluate the impact of diabetic status on outcome of patients undergoing carotid artery stenting (CAS)...

..To assess the efficacy of a comprehensive blood pressure (BP) management protocol in reducing intracerebral hemorrhage (ICH) following carotid artery stenting (CAS)...

..In an effort to characterize such a subgroup, we reviewed the results of carotid endarterectomy in patients with and without significant medical comorbidity...

..The goal is to highlight the risk of recurrent restenosis following endarterectomy. In this case report, we describe the use of cutting balloon therapy as a reasonable alternative to repeat surgical revascularization...

..Patients with these factors may require more intensive hemodynamic monitoring after CAS, including prolongation of hospitalization in some cases...

..To evaluate the feasibility of stenting and cerebral protection in patients with carotid bifurcation disease...

..The purpose of this study was to review the outcomes and durability of percutaneous transluminal angioplasty and stenting (PTA/S) for patients with RAS and decreasing renal function...

..Initial results suggest that the outcome of carotid stenting may be identical to that of endarterectomy in most patients and may also offer additional clinical benefit in patients at high risk from an open surgical approach...

..Unlike surgical revascularization, symptomatic patients did not have a greater risk for stroke and death compared with asymptomatic patients after CAS with EPDs...

..Endovascular stent graft obliteration of carotid aneurysms appears safe, feasible and a less invasive option compared to surgical repair...

..Patients who develop persistent HD are at an increased risk of periprocedural major adverse clinical events and stroke...

..9+/-8.7) and 6 (50%) had an NIHSS < or =4 at discharge. CONCLUSIONS: Multimodal rescue therapy was effective at recanalizing occluded cerebral vessels that failed thrombolysis without an excess risk of ICH...

..5 or 3 had a statistically significant reduction in MACE (OR 0.36, 95% CI 0.14-0.87, P = .02). CONCLUSIONS: Compared with SVG-PCI without emboli protection, EPD significantly improved TMP and trended towards a reduction in MACE...

..Local anesthesia permits neurological evaluations and often leads to the adjustment of the interventional technique, potentially making the procedure safer...

..In this study, we assessed the safety and efficacy of endovascular stent angioplasty in the treatment of SCD...

..Carotid stenting is currently being investigated as an alternative therapeutic intervention for these patients. This article reviews the literature pertaining to carotid intervention and its current status in 2008...

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..The presence of chronic kidney disease is associated with higher periprocedural and 6-month death, stroke, or myocardial infarction after carotid artery stenting...

..We report the utility of an IVUS-guided TransAccess catheter in overcoming this problem in the treatment of two patients with long chronic total occlusion of the superficial femoral artery...

..After ipsilateral carotid revascularization, such patients should have a repeat Doppler of the contralateral carotid to assess the true grade of stenosis...

..CONCLUSIONS: Elective intracranial stenting with DES appears to be feasible and safe, but additional clinical experience is required to assess its efficacy...

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..This report examines outcomes of carotid stenting post-approval after diffusion of this technology to a broader cross-section of physicians and hospitals...

..Given the recently published SAPPHIRE trial and other clinical trial data, it is likely that carotid artery stenting will supplant carotid endarterectomy for high-risk patients who require carotid revascularization...

..This report examines the timing, location, severity, and type of strokes occurring with CAS in the Carotid ACCULINK/ACCUNET Post Approval Trial to Uncover Unanticipated or Rare Events (CAPTURE) study...

..This report examines predictors of outcomes in carotid stenting in the earliest and largest prospective multicenter neurologist-adjudicated experience in the United States post device approval...

..We now report the 3-year results...

..However, the long-term safety and clinical efficacy of these techniques are unknown. We sought to assess the long-term outcome and efficacy of these techniques...

..New surgical techniques, drugs, and devices have substantially reduced microembolization during carotid angioplasty, CEA, and CABG...

..It is effective and has an acceptable risk profile, but ischemic complications caused by distal embolization and underlying atherothrombosis persist...

..Nitinol slotted tube stents are of great potential benefit in superficial femoral artery (SFA) interventions due to their elastic properties. However, a paucity of data exists for their efficacy in total SFA occlusions...

..1%, p = 0.02). EPDs may provide an overall safer and more effective means of neuroprotection during carotid stenting than GPIs...

..CS may be a safer carotid revascularization option for this challenging patient population...

..The association of the phenomenon with clinically symptomatic carotid lesions and use of larger stent diameters suggests that embolization of vulnerable plaque elements may play a pathogenic role...

..Distal microembolization occurs invariably during carotid stenting. Little is known about the relationship between systemic inflammation and embolization during carotid stenting...

..We report our initial experience with brachytherapy for the treatment of restenosis after carotid stenting...

..Although there was no association between BMI and short-term outcomes, patients with small BMIs were susceptible to an exaggerated long-term mortality hazard...

..These findings support the rationale and promise for combining GP IIb/IIIa blockers and LMWH for future management of acute coronary syndrome...

..We conclude that endovascular treatment of carotid artery aneurysm with Jostent is feasible and safe and may be more preferable than conventional strategies...