Research Topics
| J K StollerSummaryAffiliation: Cleveland Clinic Foundation Country: USA Publications
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Publications
Physician management and leadership education at the Cleveland Clinic Foundation: program impact and experience over 14 yearsJames K Stoller
Division of Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 55195, USA
J Med Pract Manage 22:237-42. 2007....
A review of ?1-antitrypsin deficiencyJames K Stoller
Cleveland Clinic Lerner School of Medicine, Cleveland Clinic Foundation, OH 44195, USA
Am J Respir Crit Care Med 185:246-59. 2012..Promising novel therapies are under active investigation...
Delay in diagnosis of alpha1-antitrypsin deficiency: a continuing problemJames K Stoller
Department of Pulmonary, Allergy, and Critical Care Medicine, Cleveland Clinic Foundation, A 90, 9500 Euclid Ave, Cleveland, OH 44195, USA
Chest 128:1989-94. 2005..We also determined whether individuals living near medical centers with an expressed interest in AAT deficiency experienced shorter diagnostic delays than those living at a distance...
Survey of methods of professional review for physicians in highly rated medical centersJames K Stoller
Cleveland Clinic Lerner College of Medicine, Department of Pulmonary, Allergy, and Critical Care Medicine, A90, Cleveland Clinic Foundation, 9500 Euclid Avenue, OH 44195, USA
J Med Pract Manage 22:152-8. 2006..Many, but not all, reported expending large amounts of time conducting faculty reviews, presumably reflecting the perceived value of the process...
An analysis of features of respiratory therapy departments that are avid for changeJames K Stoller
Section of Respiratory Therapy, the Respiratory Institute, Cleveland Clinic, Cleveland, Ohio, USA
Respir Care 53:871-84. 2008....
Key current clinical issues in alpha-1 antitrypsin deficiencyJames K Stoller
Department of Pulmonary and Critical Care Medicine, A90, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland OH 44195, USA
Respir Care 48:1216-21; discussion 1221-4. 2003..On that basis the standards document recommends intravenous augmentation therapy in specified clinical circumstances...
Long-term outcomes for patients discharged from a long-term hospital-based weaning unitJames K Stoller
Department of Pulmonary and Critical Care Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Chest 124:1892-9. 2003....
Inpatient consultation: results of a physician survey and a proposed improvementJames K Stoller
Section of Respiratory Therapy, Department of Pulmonary and Critical Care Medicine, Division of Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA
J Healthc Qual 25:27-35. 2003..We propose a novel process for requesting inpatient consultations that extends currently available hospital information systems but offers a process improvement that warrants development...
Developing physician-leaders: a call to actionJames K Stoller
Physician Leadership Development, Cleveland Clinic, Cleveland, OH 44195, USA
J Gen Intern Med 24:876-8. 2009..Furthermore, physicians' training can handicap their developing leadership skills. In this context, an emerging trend is for health-care institutions to offer physician-leadership programs...
Weekly versus daily changes of in-line suction catheters: impact on rates of ventilator-associated pneumonia and associated costsJames K Stoller
Department of Pulmonary and Critical Care Medicine, A 90, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland OH 44195, USA
Respir Care 48:494-9. 2003....
Developing physician-leaders: key competencies and available programsJames K Stoller
Respiratory Institute, A90, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA
J Health Adm Educ 25:307-28. 2008..Greater attention is needed to assessing the impact and effectiveness of such programs in developing leaders and benefiting organizational outcomes...
The effectiveness of respiratory care protocolsJames K Stoller
Department of Pulmonary, Allergy, and Critical Care Medicine, The Cleveland Clinic Foundation, Cleveland OH 44195, USA
Respir Care 49:761-5. 2004..help optimize the process of weaning patients from mechanical ventilation, (3). help minimize waste of oxygen, (4). allocate respiratory care services better than does physician-directed care...
alpha1-Antitrypsin deficiency . 5: intravenous augmentation therapy: current understandingJ K Stoller
Division of Medicine, Section of Respiratory Therapy, Cleveland Clinic Lerner School of Medicine, Department of Pulmonary and Critical Care Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Thorax 59:708-12. 2004..The biochemical and clinical efficacy of intravenous augmentation therapy in alpha(1)-antitrypsin deficiency is reviewed, adverse events experienced with this treatment are considered, and its cost effectiveness is discussed...
Coronary artery bypass graft and/or valvular operations following prior pneumonectomy: report of four new patients and review of the literatureJames K Stoller
Department of Pulmonary, Allergy and Critical Care Medicine, The Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA
Chest 132:295-301. 2007..To expand the experience with this challenging clinical intervention, we reviewed the reported patients with prior pneumonectomy who were undergoing cardiac surgery as well as the experience at the Cleveland Clinic...
Concordance of respiratory care plans generated by protocols from different hospitals: a comparative studyJames K Stoller
Department of Pulmonary, Allergy, and Critical Care Medicine, A90, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland OH 44195, USA
Respir Care 52:1006-12. 2007..Do protocols from different hospitals agree with regard to indications for respiratory care treatments and use of the Clinical Practice Guidelines from the American Association for Respiratory Care?..
Lung volume reduction surgery in patients with emphysema and alpha-1 antitrypsin deficiencyJames K Stoller
Division of Medicine, Section of Respiratory Therapy, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Ann Thorac Surg 83:241-51. 2007..The role of lung volume reduction surgery (LVRS) for individuals with alpha-1 antitrypsin (AAT) deficiency is unclear...
Alpha1-antitrypsin deficiencyJames K Stoller
Department of Pulmonary, Allergy, and Critical Care Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Lancet 365:2225-36. 2005..Evidence suggests that this approach is safe, slows the decline of lung function, could reduce infection rates, and might enhance survival. However, uncertainty about the cost-effectiveness of this expensive treatment remains...
Mortality in individuals with severe deficiency of alpha1-antitrypsin: findings from the National Heart, Lung, and Blood Institute RegistryJames K Stoller
Department of Pulmonary, Allergy, and Critical Care Medicine, The Cleveland Clinic Foundation, 9500 Euclid Ave, A90, Cleveland, OH 44195, USA
Chest 127:1196-204. 2005..2 years)...
Primary care diagnosis of alpha-1 antitrypsin deficiency: issues and opportunitiesJames K Stoller
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, USA
Cleve Clin J Med 74:869-74. 2007..The authors discuss impediments to diagnosis and drivers to making the diagnosis of alpha-1 antitrypsin deficiency, and they suggest several measures to enhance clinicians' recognition of the condition...
Quality-assurance research: studying processes of careJames K Stoller
Department of Pulmonary and Critical Care Medicine, A90, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Respir Care 49:1175-80. 2004..We discuss several examples of QA studies, and we offer a checklist for the process of considering, designing, executing, presenting, and publishing a QA study...
Anomalous hepatic venous drainage into the left atrium: an unusual cause of hypoxemiaJames K Stoller
Department of Pulmonary and Critical Care Medicine, The Cleveland Clinic Foundation, OH 44195, USA
Respir Care 48:58-62. 2003....
Missed bronchodilator medication treatments in respiratory therapy: frequency and underlying causesJames K Stoller
Department of Pulmonary and Critical Care Medicine, A 90, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland OH 44195, USA
Respir Care 48:110-4. 2003....
Team-building and change management in respiratory care: description of a process and outcomesJames K Stoller
Department of Pulmonary, Allergy, and Critical Care Medicine, Respiratory Institute, A90, The Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Respir Care 55:741-8. 2010..quot; This study describes an intervention that fostered teamwork among 4 separate respiratory therapy (RT) departments within a single hospital...
Formation and current results of a patient-organized registry for alpha(1)-antitrypsin deficiencyJ K Stoller
Department of Pulmonary Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Chest 118:843-8. 2000....
The impact of a respiratory therapy consult service on house officers' knowledge of respiratory care orderingJ K Stoller
Department of Pulmonary and Critical Care Medicine, The Cleveland Clinic Foundation, Ohio 44195, USA
Respir Care 45:945-52. 2000....
Implementing change in respiratory careJames K Stoller
Department of Pulmonary, Allergy, and Critical Care Medicine, Respiratory Institute, A90, The Cleveland Clinic, 9500 Euclid Avenue, Cleveland OH 44195, USA
Respir Care 55:749-57. 2010..To anchor change in our profession, greater attention should be given to developing a pipeline of respiratory care clinicians who, by virtue of their advanced training, have the skills to innovate in respiratory care in various ways...
The hospital oxygen supply: an "O2K" problemJ K Stoller
Department of Pulmonary and Critical Care Medicine, Cleveland Clinic Foundation, Ohio 44195, USA
Respir Care 45:300-5. 2000....
Clinical practice. Acute exacerbations of chronic obstructive pulmonary diseaseJames K Stoller
Division of Medicine and the Section of Respiratory Therapy, Department of Pulmonary and Critical Care Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
N Engl J Med 346:988-94. 2002
Bedside spirometry in a tertiary care hospital: the cleveland clinic experienceJames K Stoller
Department of Pulmonary and Critical Care Medicine, Section of Respiratory Therapy, The Cleveland Clinic Foundation, Ohio 44195, USA
Respir Care 47:578-82. 2002..A 1998 audit of bedside spirometry tests at our hospital showed that American Thoracic Society acceptability and reproducibility criteria were infrequently met (15% of instances)...
Oxygen and air travelJ K Stoller
Department of Pulmonary and Critical Care Medicine, Cleveland Clinic Foundation, OH 44195, USA
Respir Care 45:214-21; discussion 221-2. 2000..Significant current variation among commercial air carriers in policies regarding providing oxygen, related equipment, and the cost of in-flight oxygen poses challenges to the prospective air traveler and warrants attention...
Biochemical efficacy and safety of a new pooled human plasma alpha(1)-antitrypsin, RespitinJames K Stoller
Department of Pulmonary and Critical Care Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Chest 122:66-74. 2002..Augmentation therapy with pooled human plasma-derived alpha(1)-antitrypsin (AAT) has been shown to have biochemical efficacy in restoring serum AAT levels above the protective threshold. Also, clinical efficacy has been suggested...
Impact of a radio frequency management information system on the process and timing of providing respiratory care servicesJames K Stoller
Department of Pulmonary and Critical Care Medicine, A 90, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Respir Care 47:893-7. 2002..Having used a hand-held-device-based management information system in our Respiratory Therapy Section for 16 years, we assessed the impact of an RF system on the delivery of respiratory therapy (RT) services...
The impact of turnover among respiratory care practitioners in a health care system: frequency and associated costsJ K Stoller
Section of Respiratory Therapy, Department of Pulmonary and Critical Care Medicine, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Respir Care 46:238-42. 2001..Despite the widely shared goal of minimal turnover, neither the annual rate nor the associated expense of turnover for RTs has been described...
2000 Donald F. Egan Scientific Lecture. Are respiratory therapists effective? Assessing the evidenceJ K Stoller
Department of Pulmonary and Critical Care Medicine, Division of Medicine, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland OH 44195, USA
Respir Care 46:56-66. 2001..Finally, the respiratory therapy community must continue to cultivate and suppport investigative expertise to assure continued inquiry...
Physician-ordered respiratory care vs physician-ordered use of a respiratory therapy consult service: early experience at The Cleveland Clinic FoundationJ K Stoller
Cleveland Clinic Foundation, OH 44195
Respir Care 38:1143-54. 1993..Whether the RTCS fulfills its goal of ameliorating misallocation of respiratory care has yet to be proven and awaits the completion of other studies currently under way...
Cost impact of metered dose inhalers vs small volume nebulizers in hospitalized patients: the Cleveland Clinic experienceD K Orens
Cleveland Clinic Foundation, OH
Respir Care 36:1099-114. 1991..To extend this analysis of costs to other institutional settings, we present an analysis of projected changes in institutional costs when the volume of bronchodilator therapies and the percentage administered by MDI varies...
Augmentation therapy with alpha1-antitrypsin: patterns of use and adverse eventsJames K Stoller
Department of Pulmonary and Critical Care Medicine, Cleveland Clinic Foundation, OH, USA
Chest 123:1425-34. 2003..However, the large percentage of subjects with FEV(1) <80% predicted not receiving augmentation therapy and the frequent use of 2- to 3-week or monthly dosing reflects variation of practice from suggested treatment guidelines...
A review of alpha-1 antitrypsin deficiencyJustin Ranes
Department of Pulmonary, Allergy, and Critical Care Medicine/A90, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Semin Respir Crit Care Med 26:154-66. 2005....
Cost-effectiveness analysis of augmentation therapy for severe alpha1-antitrypsin deficiencyThomas R Gildea
Department of Pulmonary and Critical Care Medicine, The Cleveland Clinic Foundation, OH 44195, USA
Am J Respir Crit Care Med 167:1387-92. 2003..These results should encourage the development of more clinically and cost-effective therapies for alpha1-antitrypsin deficiency...
The utility of spirometry in diagnosing pulmonary restrictionSaiprakash B Venkateshiah
Department of Pulmonary, Critical Care and Sleep Medicine, Creighton University, 601 North 30th Street, Suite 3820, Omaha, Nebraska 68131, USA
Lung 186:19-25. 2008..7%). Also, a spirometric diagnosis of "restriction" (FVC<LLN and FEV1/FVC>or=LLN) had a positive predictive value of 26.3-73.9%. On this basis, normal FVC can be regarded as excluding restriction with high reliability...
The influence of mentorship and role modeling on developing physician-leaders: views of aspiring and established physician-leadersChristine A Taylor
Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, 9500 Euclid Avenue, Cleveland, OH 44195, USA
J Gen Intern Med 24:1130-4. 2009..g., grantsmanship, publications, etc.). In contrast, little attention has been given to the career development of physician-leaders (e.g., communication, vision, team-building, etc.)...
Frequency and impact of pulmonary hypertension in patients with obstructive sleep apnea syndromeOmar A Minai
Respiratory Institute, Cleveland Clinic, Ohio, USA
Am J Cardiol 104:1300-6. 2009..Female gender, younger age, obesity, and nocturnal desaturation were associated with PH. PH can cause functional limitations and increased mortality in patients with OSA...
Long-term outcome in a patient with pulmonary hypertension and hereditary hemorrhagic telangiectasiaOmar A Minai
Department of Pulmonary, Allergy, and Critical Care Medicine, A90, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
Chest 131:984-7. 2007..To our knowledge, this case represents only the second with a 10-year follow-up reported and demonstrates that aggressive therapy can lead to long-term improvement in clinical parameters and survival...
Pulmonary hypertension in lung diseases: survey of beliefs and practice patternsOmar A Minai
Department of Pulmonary, Allergy, and Critical Care, Cleveland Clinic, Cleveland, OH, USA
Respir Med 104:741-8. 2010..Pulmonary hypertension can be associated with decreased functional capacity and poor prognosis in patients with parenchymal lung diseases (PLD). Yet, little attention has been given to current beliefs and practice patterns...
Exploring leadership competencies in established and aspiring physician leaders: an interview-based studyChristine A Taylor
Faculty Development, Cleveland Clinic Lerner College of Medicine, Cleveland, OH 44195, USA
J Gen Intern Med 23:748-54. 2008..We designed this exploratory study to better understand specific perceived leadership needs of physicians from the perspective of "aspiring" and "established" leaders within our institution...
Caring for VIPs: nine principlesJorge A Guzman
Medical Intensive Care Unit, Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Cleve Clin J Med 78:90-4. 2011..Caring for VIP patients requires innovative solutions so that their VIP status does not adversely affect the care they receive. We offer nine guiding principles in caring for VIP patients...
A comparison of respiratory care workload with 2 different nebulizersEdward R Hoisington
Respiratory Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, A90, Cleveland OH 44195, USA
Respir Care 54:495-9. 2009..We studied the workload effect of adopting a faster nebulizer. We hypothesized that time saved by faster SVN treatment can be used by respiratory therapists for other patient-care activities...
Detection of upper airway obstruction with spirometry results and the flow-volume loop: a comparison of quantitative and visual inspection criteriaAriel M Modrykamien
Respiratory Institute, A90, Cleveland Clinic, 9500 Euclid Avenue, Cleveland OH 44195, USA
Respir Care 54:474-9. 2009..There are important gaps in our understanding of the epidemiology and diagnosis of upper-airway obstruction...
Laboratory evaluation of the Vortran Automatic Resuscitator Model RTMMark D Babic
Respiratory Care Services, Fairview Hospital, 18101 Lorain Avenue, Cleveland OH 44111, USA
Respir Care 52:1718-27. 2007..One device that has been proposed to address the need for emergency ventilation is the Vortran Automatic Resuscitator...
An analysis of needs for respiratory therapists in northeast Ohio and development of strategies to meet increased recruitment demandsDouglas K Orens
Section of Respiratory Therapy, M 56, The Cleveland Clinic, 9500 Euclid Avenue, Cleveland OH 44195, USA
Respir Care 52:1767-73. 2007..At the Cleveland Clinic an expected hospital expansion of 350 beds by 2008 has increased the need for RT staff. This report describes a strategy by which we developed a plan, in concert with local RT colleges, to recruit RTs...
Physician alert suggesting alpha-1 antitrypsin deficiency testing in pulmonary function test (PFT) resultsFranck Rahaghi
Department of Medicine, Cleveland Clinic Florida Fort Lauderdale Weston, 2950 Cleveland Clinic Blvd, Fort Lauderdale Weston, FL 33331, USA
COPD 6:26-30. 2009..The incomplete rate of testing suggests the need for additional strategies to enhance clinicians' detection of individuals with AATD...
Detection of alpha-1 antitrypsin deficiency: a reviewLoutfi S Aboussouan
Cleveland Clinic Foundation, Respiratory Institute, OH 44195, USA
Respir Med 103:335-41. 2009....
Women with ulcerating, painful skin lesionsMelissa P Piliang
Department of Dermatology, Cleveland Clinic Foundation, OH 44195, USA
Cleve Clin J Med 75:414, 418, 422. 2008
Augmentation therapy in alpha-1 antitrypsin deficiencyGustavo A Heresi
Respiratory Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA
Expert Opin Biol Ther 8:515-26. 2008..Alpha-1 antitrypsin deficiency is a genetic disorder that leads to early-onset emphysema. Recently, exogenous supplementation of the enzyme has become a therapeutic alternative...
Pneumonia due to Cryptococcus neoformans in a patient receiving infliximab: possible zoonotic transmission from a pet cockatielRabin K Shrestha
Division of Microbiology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Respir Care 49:606-8. 2004..A temporally related exposure history raised the possibility that our patient acquired the infection from his pet cockatiel. It seems prudent to advise patients receiving infliximab to avoid exposure to pet avian excreta...
Small cell carcinoma with paraneoplastic polyneuropathy and tumor embolization: a case report and literature reviewManica Sodhi
Department of Pulmonary and Critical Care Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
Respiration 79:77-80. 2010..To our knowledge, this patient represents only the second individual to be described with tumor embolization complicating small cell cancer and reminds clinicians of the extended spectrum of this disease...
Pulmonary venous thrombosis and infarction complicating pulmonary venous stenosis following radiofrequency ablationJose Yataco
Department of Pulmonary, Allergy, and Critical Care Medicine, A90, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland OH 44195, USA
Respir Care 49:1525-7. 2004....
Estimating FVC from FEV2 and FEV3: assessment of a surrogate spirometric parameterOctavian C Ioachimescu
Department of Pulmonary, Allergy, and Critical Care Medicine, The Cleveland Clinic Foundation, 9500 Euclid Ave A90, Cleveland, OH 44195, USA
Chest 128:1274-81. 2005..In the context that accurate measurement of FVC is important in diagnosing airflow obstruction and in assessing restriction, strategies to achieve reliable and accurate FVC measurement have drawn much attention...
A review of physician turnover: rates, causes, and consequencesAnita D Misra-Hebert
Department of General Internal Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Am J Med Qual 19:56-66. 2004..Our review suggests that greater attention to physician turnover is needed to clarify its frequency and predictors, and strategies to lessen its occurrence...
Respiratory care continuing educationLucy Kester
Respiratory Therapy Section of the Pulmonary, Allergy, and Critical Care Medicine Department, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Respir Care Clin N Am 11:505-15. 2005..Evaluation methods for continuing education programs have focused on attendees' ratings but should be revised to emphasize the impact of the educational program on beneficial changes in practice...
Severe agitation among ventilated medical intensive care unit patients: frequency, characteristics and outcomesJeffery C Woods
Critical Care and Step-down Nursing, Huron Hospital, Cleveland, Ohio, USA
Intensive Care Med 30:1066-72. 2004..CONCLUSION: Severe agitation occurs commonly in critically ill patients and is associated with adverse events including longer ICU stays, duration of mechanical ventilation and self-extubation...
Smoking cessationScott P Marlow
Department of Pulmonary and Critical Care Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Respir Care 48:1238-54; discussion 1254-6. 2003..However, since respiratory therapists interact with smokers frequently, we believe it is particularly important for respiratory therapists to show leadership in implementing smoking cessation...
Basilar hyperlucency in a patient with emphysema due to hypocomplementemic urticarial vasculitis syndromeZiad Ghamra
Department of Pulmonary and Critical Care Medicine, A90, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland OH 44195, USA
Respir Care 48:697-9. 2003..To the extent that basilar hyperlucency has not been well recognized as a feature of hypocomplementemic urticarial vasculitis syndrome, this report extends the spectrum of causes of this unusual radiographic pattern of emphysema...
Low levels of nitric oxide and carbon monoxide in alpha 1-antitrypsin deficiencyRoberto F Machado
Department of Pulmonary and Critical Care Medicine, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
J Appl Physiol 93:2038-43. 2002..Demonstration of lower than normal CO and NO levels may be useful as an additional noninvasive method to evaluate alpha(1)-AT deficiency in individuals with a severe, early onset of obstructive lung disease...
The bronchopulmonary pathology of alpha-1 antitrypsin (AAT) deficiency: findings of the Death Review Committee of the national registry for individuals with Severe Deficiency of Alpha-1 AntitrypsinJoseph F Tomashefski
Department of Pathology, MetroHealth Medical Center and Case Western Reserve University School of Medicine, Cleveland, OH 44109-1998, USA
Hum Pathol 35:1452-61. 2004....
Right-to-left anatomic shunt associated with a persistent left superior vena cava: the importance of injection site in demonstrating the shuntNandhitha N Thaiyananthan
Pulmonary, Critical Care and Sleep Medicine Division, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH, USA
Chest 136:617-20. 2009..This case reminds pulmonary clinicians, who are frequently called on to assess the cause of hypoxemia, that specifying a contrast injection into the left arm is required in the pursuit of this specific shunt-producing anomaly...
Use of noninvasive positive-pressure ventilation on the regular hospital ward: experience and correlates of successSamar Farha
Department of Pulmonary, Allergy, and Critical Care Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Respir Care 51:1237-43. 2006....
Emphysema in nonsmokers: alpha 1-antitrypsin deficiency and other causesPyng Lee
Department of Pulmonary and Critical Care Medicine, The Cleveland Clinic Foundation, OH 44195, USA
Cleve Clin J Med 69:928-9, 933, 936 passim. 2002....
Cost-effectiveness of population screening for alpha-1 antitrypsin deficiency: a decision analysisKenneth M Shermock
Center for Pharmaceutical Outcomes and Policy, The Johns Hopkins Hospital, Cleveland, Ohio, USA
COPD 2:411-8. 2005..While population-based screening for AAT deficiency is not cost-effective under current conditions, cost-effectiveness criteria could be satisfied when case-finding in a high prevalence population is undertaken...
A comparative analysis of arranging in-flight oxygen aboard commercial air carriersJ K Stoller
Department of Pulmonary and Critical Care Medicine, Cleveland Clinic Foundation, OH 44106, USA
Chest 115:991-5. 1999..On the premise that such variation may cause confusion by prospective air travelers, we undertook the current study to describe individual air carriers' policies and practices and to provide guidance to future air travelers...
Spirometry: a key diagnostic test in pulmonary medicineJ K Stoller
Department of Pulmonary Disease, Cleveland Clinic Foundation, OH 44195
Cleve Clin J Med 59:75-8. 1992..As a simple, inexpensive, and informative test, spirometry should be used liberally in assessing patients with respiratory symptoms...
Exogenous granulocyte-macrophage colony-stimulating factor administration for pulmonary alveolar proteinosisM S Kavuru
Department of Pulmonary and Critical Care Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Am J Respir Crit Care Med 161:1143-8. 2000..We conclude that GM-CSF appears to benefit a subset of patients with adult PAP, and may represent an alternative to whole-lung lavage in treating the disease...
Frequency and causes of combined obstruction and restriction identified in pulmonary function tests in adultsEnrique Diaz-Guzman
Department of Pulmonary and Critical Care Medicine, Respiratory Institute, The Cleveland Clinic, Cleveland, Ohio 44195, USA
Respir Care 55:310-6. 2010..Moreover, although the causes of combined-obstruction-and-restriction patterns are known, the frequency of the various etiologies has received little attention...
Impact of an annual retreat on process improvement in a respiratory therapy sectionVincent T Roberts
Section of Respiratory Therapy, Department of Pulmonary, Allergy, and Critical Care Medicine, The Cleveland Clinic Foundation, OH 44195, USA
Respir Care 50:1654-8. 2005....
Changing patterns of inpatient respiratory care services over a decade at the Cleveland Clinic: challenges posed and proposed responsesDouglas K Orens
Department of Pulmonary, Allergy and Critical Care Medicine, The Cleveland Clinic Foundation, Ohio 44195, USA
Respir Care 50:1033-9. 2005..We believe that a focus on the process of care, including enhanced professionalism, communication, and participation, has permitted a favorable response to these rising demands...
Augmentation therapy for alpha(1)-antitrypsin deficiencyGeorges S Juvelekian
Department of Pulmonary, Allergy, and Critical Care Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Drugs 64:1743-56. 2004..Despite its high cost, intravenous AAT augmentation therapy remains the only US FDA-approved treatment option for patients with AAT deficiency. Research into new and evolving treatments is currently underway...
Right hemidiaphragmatic elevation with a right-to-left interatrial shunt through a patent foramen ovale: a case report and literature reviewS Ghamande
Department of Pulmonary and Critical Care Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Chest 120:2094-6. 2001....
Pulmonary involvement in Niemann-Pick disease: case report and literature reviewO A Minai
Department of Pulmonary and Critical Care Medicine, The Cleveland Clinic Foundation, Ohio 44195, USA
Respir Med 94:1241-51. 2000..This case is unique in that it provides the longest physiological follow-up in the literature, and provides data on the natural history of pulmonary involvement in NPD...
Successful lecturing: a prospective study to validate attributes of the effective medical lectureH L Copeland
Division of Education, Cleveland Clinic Foundation, OH 44195, USA
J Gen Intern Med 15:366-71. 2000..We believe our findings are useful for lecturers wanting to improve their effectiveness and for educators who design continuing medical education curricula...
Impact of a clinical decision support system in an electronic health record to enhance detection of ??-antitrypsin deficiencyAnil Jain
Internal Medicine and Information Technology Division, Cleveland Clinic Lerner College of Medicine, Cleveland, OH, USA
Chest 140:198-204. 2011..Because ?(1)-antitrypsin deficiency (AATD) is underrecognized, strategies to enhance guideline-based diagnostic testing are warranted...
Asthma features in severe alpha1-antitrypsin deficiency: experience of the National Heart, Lung, and Blood Institute RegistryEdward Eden
James P Mara Center for Lung Disease, St Luke s Roosevelt Hospital Center, New York, NY 10019, USA
Chest 123:765-71. 2003..To describe asthma features in a cohort with alpha(1)-antitrypsin (AAT) deficiency, and determine the impact of asthma on FEV(1) decline...
IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiencyDawn L DeMeo
Brigham and Women s Hospital, Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA
Am J Respir Cell Mol Biol 38:114-20. 2008..Haplotype analysis of IL10 SNPs suggested the strongest association with IL10 promoter SNPs. IL10 is likely an important modifier gene for the development of COPD in individuals with severe AAT deficiency...
Alpha-1 antitrypsin deficiency: an under-recognized but important issue for respiratory therapistsJames K Stoller
Respir Care 48:1022-4. 2003
Risk factors for symptom onset in PI*Z alpha-1 antitrypsin deficiencyAnnyce S Mayer
Division of Environmental and Occupational Health Sciences National Jewish Medical and Research Center, Denver, CO 80206, USA
Int J Chron Obstruct Pulmon Dis 1:485-92. 2006..Age of symptom onset has not been well studied in relationship to other environmental exposures...
Respiratory therapists' attitudes about participative decision making: relationship between managerial decision-making style and job satisfactionShane S Blake
Section of Respiratory Therapy, Department of Pulmonary, Allergy, and Critical Care Medicine, The Cleveland Clinic Foundation, Ohio 44195, USA
Respir Care 49:917-25. 2004..These findings offer guidance for organizing optimal work environments for RTs...
Diffuse alveolar hemorrhage: diagnosing it and finding the causeOctavian C Ioachimescu
Division of Pulmonary, Critical Care, and Sleep Medicine, Emory University, Atlanta, GA, USA
Cleve Clin J Med 75:258, 260, 264-5 passim. 2008..Its many causes and presentations pose an important challenge to the clinician...
Results of a survey of patients with alpha-1 antitrypsin deficiencyCharlie Strange
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Medical University of South Carolina, Charleston, 29425, USA
Respiration 73:185-90. 2006..alpha(1)-Antitrypsin deficiency (AATD) is an uncommon genetic disease which occurs in 1-2.5% of Americans with chronic obstructive pulmonary disease (COPD). Little is known about current demographics of AATD...
alpha1-Antitrypsin augmentation therapy for PI*MZ heterozygotes: a cautionary noteRobert A Sandhaus
National Jewish Medical and Research Center, Denver, CO, USA
Chest 134:831-4. 2008..This commentary discusses the treatment of AAT deficiency and the concerns regarding treatment of PI*MZ individuals. We conclude that clinicians should avoid prescribing augmentation therapy for this heterozygote population...
Role of flexible bronchoscopy in immunocompromised patients with lung infiltratesPrasoon Jain
Department of Medicine, Louis A. Johnson Veterans Affairs Medical Center, Clarksburg, WV, USA
Chest 125:712-22. 2004..CONCLUSIONS: FB has a high diagnostic yield in immunocompromised patients with pulmonary infiltrates. Based on our results, we recommend performing TBB in these patients, whenever possible...
Determinants of airflow obstruction in severe alpha-1-antitrypsin deficiencyDawn L DeMeo
Channing Laboratory, 181 Longwood Avenue, Boston, Massachusetts 02115, USA
Thorax 62:806-13. 2007..A study was undertaken to assess the impact of chronic bronchitis, pneumonia, asthma and sex on the development of COPD in individuals with severe AAT deficiency...
Disease management as an evolving role for respiratory therapistsJames K Stoller
Respir Care 51:1400-2. 2006
A 45-year-old woman with systemic lupus erythematosus and progressive dyspneaDrew Allen
Department of Pulmonary, Allergy, and Critical Care Medicine, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44124, USA
Chest 131:1252-5. 2007
Impact of a program to provide patients with comparative information about providers of durable medical equipment for home respiratory careEdward R Hoisington
Section of Respiratory Therapy, Department of Pulmonary and Critical Care Medicine, The Cleveland Clinic Foundation, OH 44195, USA
Respir Care 49:1309-15. 2004..The trend toward prompter respiratory therapists' visits to the home and better availability of oxygen canisters for at-home patients suggested benefits from the enhanced information program...
Teambuilding and leadership training in an internal medicine residency training programJames K Stoller
Department of Pulmonary, Allergy and Critical Care Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
J Gen Intern Med 19:692-7. 2004..In the context that this 1-day retreat was deemed useful by faculty and residents alike, further study is needed to assess the impact of this learning on actual clinical practice and the durability of these lessons...
