Research Topics
| Ali R RezaiSummaryAffiliation: Cleveland Clinic Foundation Country: USA Publications
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Detail Information
Publications
Fracture of subthalamic nucleus deep brain stimulation hardware as a result of compulsive manipulation: case reportAndre G Machado
The Cleveland Clinic Foundation, Center for Neurological Restoration Cleveland, Ohio 44195, USA
Neurosurgery 57:E1318; discussion E1318. 2005..Furthermore, there is also an implication that the pathophysiology of PD and TTM may be intertwined...
Surgery for movement disordersAli R Rezai
Center for Neurological Restoration, and Department of Neurosurgery, Cleveland Clinic, Cleveland, Ohio 44122, USA
Neurosurgery 62:809-38; discussion 838-9. 2008..In this article, we provide a review of the history, neurocircuitry, indication, technical aspects, outcomes, complications, and emerging neurosurgical approaches for the treatment of movement disorders...
Deep brain stimulation for Parkinson's disease: surgical issuesAli R Rezai
Department of Neurosurgery, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Mov Disord 21:S197-218. 2006..It outlines answers to a series of questions developed to address all surgical aspects of deep brain stimulation...
Deep brain stimulation for Parkinson's disease: surgical technique and perioperative managementAndre Machado
Center for Neurological Restoration, Department of Neurosurgery, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Mov Disord 21:S247-58. 2006..The various aspects of DBS surgery will be presented...
Electrophysiological mapping for the implantation of deep brain stimulators for Parkinson's disease and tremorRobert E Gross
Department of Neurosurgery, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Mov Disord 21:S259-83. 2006..The increase in surgical risk of intracranial hemorrhage correlated to the number of microelectrode trajectories must be considered against the risk of suboptimal benefits related to omission of this technique...
Evaluation of specific absorption rate as a dosimeter of MRI-related implant heatingKenneth B Baker
Department of Neurology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk S 90, Cleveland, OH 44195, USA
J Magn Reson Imaging 20:315-20. 2004..To compare the magnetic resonance imaging (MRI)-related heating per unit of whole body averaged specific absorption rate (SAR) of a conductive implant exposed to two different 1.5-Tesla/64 MHz MR systems...
Is magnetic resonance imaging safe for patients with neurostimulation systems used for deep brain stimulation?Ali R Rezai
Center for Neurological Restoration, Department of Neurosurgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Neurosurgery 57:1056-62; discussion 1056-62. 2005
Reduction of magnetic resonance imaging-related heating in deep brain stimulation leads using a lead management deviceKenneth B Baker
Center for Neurological Restoration, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
Neurosurgery 57:392-7; discussion 392-7. 2005....
Subthalamic nucleus stimulation in patients with a prior pallidotomyAlon Y Mogilner
Department of Neurosurgery, New York University School of Medicine, New York, USA
J Neurosurg 96:660-5. 2002..Potential alterations in physiological features of the STN after pallidotomy may complicate localization of this structure in this group of patients...
Motor cortex stimulation for refractory benign painAndre Machado
Center for Neurological Restoration, Cleveland Clinic Neurological Institute, Cleveland, Ohio, USA
Clin Neurosurg 54:70-7. 2007
Anatomy and physiology of the basal ganglia: implications for deep brain stimulation for Parkinson's diseaseBrian H Kopell
Department of Neurosurgery, Medical College of Wisconsin, and Clement J Zablocki VA Medical Center, Milwaukee, Wisconsin 53202, USA
Mov Disord 21:S238-46. 2006..Finally, the current understandings of the mechanisms underpinning the beneficial effects of deep brain stimulation for PD will be discussed...
Permanent neurological deficit related to magnetic resonance imaging in a patient with implanted deep brain stimulation electrodes for Parkinson's disease: case reportJaimie M Henderson
Department of Neurosurgery, Stanford University, Stanford, California, USA
Neurosurgery 57:E1063; discussion E1063. 2005....
Neurostimulation systems: assessment of magnetic field interactions associated with 1.5- and 3-Tesla MR systemsKenneth B Baker
Department of Neurology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
J Magn Reson Imaging 21:72-7. 2005..These findings have important implications for patients with these implants who are referred for MRI examinations...
Long-term outcomes of spinal cord stimulation with paddle leads in the treatment of complex regional pain syndrome and failed back surgery syndromeNathaniel C Sears
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA
Neuromodulation 14:312-8; discussion 318. 2011..Numerical rating scales such as the NRS-11 remain the most common outcome measure in the literature, although they may not accurately correlate with quality of life improvements and overall satisfaction...
Deep brain stimulation of the ventral capsule/ventral striatum for treatment-resistant depressionDonald A Malone
Department of Psychiatry and Psychology, Center for Neurological Restoration, Cleveland Clinic, Cleveland, Ohio, USA
Biol Psychiatry 65:267-75. 2009..We investigated the use of deep brain stimulation (DBS) of the ventral capsule/ventral striatum (VC/VS) for treatment refractory depression...
Deep brain stimulation for movement disordersJoshua M Rosenow
Department of Neurosurgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
Neurol Res 26:9-20. 2004..This review will discuss the history of this technology as well as the mechanisms of action, current clinical indications, and future prospects for the treatment of movement disorders...
Variability in RF-induced heating of a deep brain stimulation implant across MR systemsKenneth B Baker
Center for Neurological Restoration, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
J Magn Reson Imaging 24:1236-42. 2006..To compare the MRI-related heating per unit of specific absorption rate (SAR) profile of a conductive implant between two 1.5-Tesla/64 MHz MR systems using a transmit/receive (t/r) head coil configuration...
Neurostimulation system used for deep brain stimulation (DBS): MR safety issues and implications of failing to follow safety recommendationsAli R Rezai
The Cleveland Clinic Foundation, Cleveland, OH, USA
Invest Radiol 39:300-3. 2004..4 W/kg; etc.) may result in serious, temporary, or permanent injury to the patient including the possibility of transient dystonia, paralysis, coma, or even death...
Deep brain stimulation for obsessive-compulsive disorder: using functional magnetic resonance imaging and electrophysiological techniques: technical case reportKenneth B Baker
Department of Neuroscience, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Neurosurgery 61:E367-8; discussion E368. 2007....
Treatment of chronic pain with neurostimulationJohn K Birknes
Department of Neurosurgery, Thomas Jefferson University, Philadelphia, PA 19107, USA
Prog Neurol Surg 19:197-207. 2006..This chapter reports on the current evidence for the use of neurostimulation (i.e. spinal cord stimulation, motor cortex stimulation and deep brain stimulation) in the treatment of chronic pain conditions...
Intracranial hemorrhage after removal of deep brain stimulation electrodesJames K C Liu
Center for Neurological Restoration, Department of Neurosurgery, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
J Neurosurg 116:525-8. 2012..The authors performed a retrospective chart review to identify the incidence and trends in hemorrhage after DBS electrode removal...
MR imaging-related heating of deep brain stimulation electrodes: in vitro studyDaniel A Finelli
Division of Radiology, Section of Stereotactic and Functional Neurosurgery, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
AJNR Am J Neuroradiol 23:1795-802. 2002..Clinical imaging sequences that are associated with tolerable temperature elevations in the <or=2.0 degrees C range at the electrode tips can be performed safely within an SAR range <2.4 W/kg local (0.9 W/kg whole body averaged)...
Parkinson disease: pattern of functional MR imaging activation during deep brain stimulation of subthalamic nucleus--initial experienceMicheal D Phillips
Departments of Radiology, Neurology, and Neurosurgery, Cleveland Clinic Foundation, Mellen Center U 15, 9500 Euclid Ave, Cleveland, OH 44195, USA
Radiology 239:209-16. 2006....
Failure modes of spinal cord stimulation hardwareJoshua M Rosenow
Department of Neurosurgery, Feinberg School of Medicine of Northwestern University, Chicago, Illinois 60611, USA
J Neurosurg Spine 5:183-90. 2006..The failure modes of the implanted hardware, however, have not been well studied. A better understanding of this could aid in improving the current procedure or designing future devices...
Not your father's lobotomy: psychiatric surgery revisitedBrian Harris Kopell
Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, USA
Clin Neurosurg 52:315-30. 2005
A preliminary study of transient confusional states following bilateral subthalamic stimulation for Parkinson's diseaseJulie G Pilitsis
Department of Neurosurgery, Wayne State University, Detroit, Michigan, USA
Stereotact Funct Neurosurg 83:67-70. 2005..We provide preliminary evidence that patients with depression and frontal-subcortical dysfunction are more likely to develop POC, and that POC is more often associated with cognitive decline following surgery...
A feasibility study of optical coherence tomography for guiding deep brain probesSung W Jeon
Center for Neurological Restoration, Cleveland Clinic Foundation, OH 44195, USA
J Neurosci Methods 154:96-101. 2006..White matter tends to have higher peak reflectivity and steeper attenuation rate compared to gray matter. This structural information may help guide DBS probe advance and electrical measurements...
3-D microfabricated electrodes for targeted deep brain stimulationNoppasit Laotaveerungrueng
Department of Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, OH 44106, USA
Conf Proc IEEE Eng Med Biol Soc 2009:6493-6. 2009..6 times larger than that on the corresponding two adjacent, not-activated sides, and 9 times larger than the corresponding opposite, not-activated side...
Subthalamic nucleus deep brain stimulus evoked potentials: physiological and therapeutic implicationsKenneth B Baker
Movement Disorders Program, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Mov Disord 17:969-83. 2002..The potential implications of the types of responses observed as well as potential applications are discussed...
A model predicting optimal parameters for deep brain stimulation in essential tremorScott E Cooper
Department of Neurology, Center for Neurological Restoration Cleveland Clinic Foundation, Cleveland, Ohio, USA
J Clin Neurophysiol 25:265-73. 2008..A mathematical model based on "competing processes" successfully predicts optimum voltage in individual patients. This supports a competing processes model of deep brain stimulation effects...
Methods of scalp revision for deep brain stimulator hardware: case reportAlejandro M Spiotta
Department of Neurological Surgery, Cleveland Clinic, Cleveland, Ohio 44195, USA
Neurosurgery 62:249-50; discussion 250. 2008..The patient's relief of symptoms after DBS will be limited by hardware-related complications and thus, strategies to revise scalp overlying hardware are important in the widespread application of DBS...
Precentral stimulation for chronic painAshwini D Sharan
Department of Neurosurgery, Thomas Jefferson University, 909 Walnut Street, Third Floor, Philadelphia, PA 19107, USA
Neurosurg Clin N Am 14:437-44. 2003..More scientific evidence is warranted to understand the precise mechanisms for this treatment modality. A larger organized clinical trial is desired to establish the efficacy of precentral stimulation...
Deep brain stimulation for psychiatric disordersBrian Harris Kopell
Center for Neurological Restoration, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
J Clin Neurophysiol 21:51-67. 2004..The few published studies on DBS for obsessive-compulsive disorder (OCD) suggest that this can be done safely. While efficacy data are still uncertain, initial data are promising...
Recovery of pain control by intensive reprogramming after loss of benefit from motor cortex stimulation for neuropathic painJaimie M Henderson
Center for Neurological Restoration, Cleveland Clinic Foundation, Cleveland, Ohio, USA
Stereotact Funct Neurosurg 82:207-13. 2004..We investigated whether intensive reprogramming could recapture the beneficial effects of MCS...
Axonal pathways linked to therapeutic and nontherapeutic outcomes during psychiatric deep brain stimulationJ Luis Lujan
Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Hum Brain Mapp 33:958-68. 2012..As such, the goal of this study was to develop a method for identifying axonal pathways whose activation is most likely necessary for achieving therapeutic benefits during DBS...
Neurostimulation systems for deep brain stimulation: in vitro evaluation of magnetic resonance imaging-related heating at 1.5 teslaAli R Rezai
Section of Stereotactic and Functional Neurosurgery, Department of Neurosurgery, Cleveland Clinic Foundation, Cleveland, Ohio, USA
J Magn Reson Imaging 15:241-50. 2002..Based on this information, MR safety guidelines are provided. These observations are restricted to the tested neurostimulation system...
Neurophysiological refinement of subthalamic nucleus targetingDjordje Sterio
Department of Neurosurgery, New York University School of Medicine, 301 East 17th Street, New York, NY 10003, USA
Neurosurgery 50:58-67; discussion 67-9. 2002..Microelectrode recording is a helpful targeting adjunct that will continue to facilitate our understanding of basal ganglion physiological features...
Mechanisms and the current state of deep brain stimulation in neuropsychiatryBenjamin D Greenberg
Department of Psychiatry and Human Behavior, Brown University School of Medicine, Providence, Rhode Island, USA
CNS Spectr 8:522-6. 2003..These investigations should proceed cautiously...
Pulse-to-pulse changes in the frequency of deep brain stimulation affect tremor and modeled neuronal activityMerrill J Birdno
Department of Biomedical Engineering, Duke University, Hudson Hall, Room 136, Box 90281, Durham, NC 27708 0281, USA
J Neurophysiol 98:1675-84. 2007..Modeling results also suggest that effective DBS overrides oscillatory pathological activity and replaces it with more regularized neuronal firing patterns...
Location of the active contact within the subthalamic nucleus (STN) in the treatment of idiopathic Parkinson's diseaseMartin Zonenshayn
New York University Center for Functional and Restorative Neurosurgery, New York, New York, USA
Surg Neurol 62:216-25; discussion 225-6. 2004..Further studies are crucial in determining the precise mechanism of various modes of DBS in an effort to maximize clinical outcome...
Three-year outcomes in deep brain stimulation for highly resistant obsessive-compulsive disorderBenjamin D Greenberg
Department of Psychiatry and Human Behavior, Brown Medical School, Butler Hospital and Rhode Island Hospital, Providence, RI 02906, USA
Neuropsychopharmacology 31:2384-93. 2006..This open study found promising long-term effects of DBS in highly treatment-resistant OCD...
Neurosurgery for intractable obsessive-compulsive disorder and depression: critical issuesBenjamin D Greenberg
Department of Psychiatry and Human Behavior, Brown Medical School, Butler Hospital, 345 Blackstone Boulevard, Providence, RI 02906, USA
Neurosurg Clin N Am 14:199-212. 2003....
What's in a "smile?" Intra-operative observations of contralateral smiles induced by deep brain stimulationMichael S Okun
Movement Disorders Center, University of Florida, Department of Neurology, McKnight Brain Institute, Gaineville, FL 32610, USA
Neurocase 10:271-9. 2004..To describe smiling and euphoria induced by deep brain stimulation (DBS)...
Deep brain stimulation for Parkinson's diseaseAlim-Louis Benabid
Grenoble, France
Mov Disord 21:S168-70. 2006
Temporal excitation properties of paresthesias evoked by thalamic microstimulationWarren M Grill
Department of Biomedical Engineering, Duke University, Durham, NC 27708 0281, USA
Clin Neurophysiol 116:1227-34. 2005..The neuronal elements mediating the effects of deep brain stimulation (DBS) are unknown. The objective was to determine the strength-duration properties of the neuronal elements that mediate paresthesias evoked by thalamic microstimulation...
Clinical response to varying the stimulus parameters in deep brain stimulation for essential tremorAlexis M Kuncel
Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708-0281, USA
Mov Disord 21:1920-8. 2006..Improved understanding of the relationships between stimulus parameters and clinical responses may lead to improved techniques of stimulus parameter adjustment...
Deep brain stimulation for chronic neuropathic pain: long-term outcome and the incidence of insertional effectClement Hamani
Division of Neurosurgery, Toronto Western Hospital, Toronto, Ont, Canada
Pain 125:188-96. 2006..The relatively low efficacy of DBS for the treatment of neuropathic pain stresses the need for further investigation and the exploration of new surgical targets...
Deep brain stimulation for psychiatric disordersBart Nuttin
Neurosurg Clin N Am 14:xv-xvi. 2003
