S M Dombrowski

Summary

Affiliation: Cleveland Clinic Foundation
Country: USA

Publications

  1. ncbi Drug resistance in epilepsy: the role of the blood-brain barrier
    N Joan Abbott
    Blood Brain Barrier Research Group, Centre for Neuroscience Research, King's College London, UK
    Novartis Found Symp 243:38-47; discussion 47-53, 180-5. 2002
  2. ncbi Chronic hydrocephalus-induced changes in cerebral blood flow: mediation through cardiac effects
    Stephen M Dombrowski
    Department of Neurological Surgery, Pediatric and Congenital Neurological Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Cereb Blood Flow Metab 26:1298-310. 2006
  3. ncbi An experimental in-vivo canine model for adult shunt infection
    Roger Bayston
    Department of Neurosurgery S80, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH, 44195, USA
    Cerebrospinal Fluid Res 5:17. 2008
  4. ncbi Chronic hydrocephalus-induced hypoxia: increased expression of VEGFR-2+ and blood vessel density in hippocampus
    S M Dombrowski
    Department of Neurosurgery, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Neuroscience 152:346-59. 2008
  5. ncbi Dissociation between vascular endothelial growth factor receptor-2 and blood vessel density in the caudate nucleus after chronic hydrocephalus
    Abhishek Deshpande
    Department of Neurological Surgery, Section of Pediatric and Congenital Neurological Surgery, CSF Physiology Laboratory, Neurological Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Cereb Blood Flow Metab 29:1806-15. 2009
  6. ncbi VEGF/VEGFR-2 changes in frontal cortex, choroid plexus, and CSF after chronic obstructive hydrocephalus
    Jun Yang
    Department of Neurological Surgery, Section of Pediatric and Congenital Neurological Surgery, CSF Physiology Laboratory, Neurological Institute, Cleveland Clinic, S 60, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA
    J Neurol Sci 296:39-46. 2010
  7. ncbi Regional variation in brain capillary density and vascular response to ischemia
    M Cavaglia
    Cerebrovascular Research Center, Department of Neurological Surgery, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Brain Res 910:81-93. 2001
  8. ncbi Chronic hydrocephalus in adults
    Richard J Edwards
    Department of Neurosurgery, Frenchay Hospital, Bristol, United Kingdom
    Brain Pathol 14:325-36. 2004

Collaborators

Detail Information

Publications8

  1. ncbi Drug resistance in epilepsy: the role of the blood-brain barrier
    N Joan Abbott
    Blood Brain Barrier Research Group, Centre for Neuroscience Research, King's College London, UK
    Novartis Found Symp 243:38-47; discussion 47-53, 180-5. 2002
    ..This complicates interpretation of drug resistance in epilepsy, and therapeutic strategies...
  2. ncbi Chronic hydrocephalus-induced changes in cerebral blood flow: mediation through cardiac effects
    Stephen M Dombrowski
    Department of Neurological Surgery, Pediatric and Congenital Neurological Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Cereb Blood Flow Metab 26:1298-310. 2006
    ..The relationship between cardiac function and CBF should be considered in the pathophysiology and clinical treatment of CH...
  3. ncbi An experimental in-vivo canine model for adult shunt infection
    Roger Bayston
    Department of Neurosurgery S80, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH, 44195, USA
    Cerebrospinal Fluid Res 5:17. 2008
    ..The intention of this pilot study was to show that the canine hydrocephalus model could be shunted using conventional "human" shunts, and that a shunt infection could be established so that further studies could then be planned...
  4. ncbi Chronic hydrocephalus-induced hypoxia: increased expression of VEGFR-2+ and blood vessel density in hippocampus
    S M Dombrowski
    Department of Neurosurgery, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Neuroscience 152:346-59. 2008
    ..Modulation of vascular endothelial growth factor/VEGFR-2(+) may be important in developing treatments for hypoxic conditions including hydrocephalus and other forms of cerebral ischemia...
  5. ncbi Dissociation between vascular endothelial growth factor receptor-2 and blood vessel density in the caudate nucleus after chronic hydrocephalus
    Abhishek Deshpande
    Department of Neurological Surgery, Section of Pediatric and Congenital Neurological Surgery, CSF Physiology Laboratory, Neurological Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Cereb Blood Flow Metab 29:1806-15. 2009
    ..These observed findings suggest that destructive forces may outweigh angiogenic forces and possibly show a disassociation between VEGFR-2 and BV expressions...
  6. ncbi VEGF/VEGFR-2 changes in frontal cortex, choroid plexus, and CSF after chronic obstructive hydrocephalus
    Jun Yang
    Department of Neurological Surgery, Section of Pediatric and Congenital Neurological Surgery, CSF Physiology Laboratory, Neurological Institute, Cleveland Clinic, S 60, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA
    J Neurol Sci 296:39-46. 2010
    ....
  7. ncbi Regional variation in brain capillary density and vascular response to ischemia
    M Cavaglia
    Cerebrovascular Research Center, Department of Neurological Surgery, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Brain Res 910:81-93. 2001
    ..We conclude that in addition to neuronal and glial heterogeneity, cortical structures are also endowed with region-specific vascular patterns characterized by distinct pathophysiological responses...
  8. ncbi Chronic hydrocephalus in adults
    Richard J Edwards
    Department of Neurosurgery, Frenchay Hospital, Bristol, United Kingdom
    Brain Pathol 14:325-36. 2004
    ..Recent research has challenged previously held tenets regarding the CSF circulatory system and this in turn has led to a radical rethinking of the pathophysiological basis of chronic hydrocephalus...