Research Topics
| John R BartholomewSummaryAffiliation: Cleveland Clinic Foundation Country: USA Publications
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Detail Information
Publications
Air travel and venous thromboembolism: minimizing the riskJohn R Bartholomew
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA
Cleve Clin J Med 78:111-20. 2011..The goal of this publication is to provide an overview of how best to prevent VTE during travel, and how to diagnose and treat it...- Argatroban anticoagulation for heparin-induced thrombocytopenia in elderly patientsJohn R Bartholomew
The Cleveland Clinic, Cleveland, Ohio 44195, USA
Drugs Aging 24:489-99. 2007..Argatroban, a direct thrombin inhibitor that has reduced clearance in elderly versus younger volunteers, is used for thromboprophylaxis or treatment in heparin-induced thrombocytopenia (HIT)... - Pathophysiology of peripheral arterial disease and risk factors for its developmentJohn R Bartholomew
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA
Cleve Clin J Med 73:S8-14. 2006..More recently, a number of nontraditional risk factors for PAD have also been recognized. This article briefly reviews the pathophysiology of PAD and the evidence supporting established and emerging risk factors for its development... - The incidence and clinical features of heparin-induced thrombocytopeniaJohn R Bartholomew
Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
Semin Hematol 42:S3-8. 2005..Awareness of the clinical features and different presentations of HIT are essential for preventing severe morbidity and mortality associated with this disease... - Transitioning from argatroban to warfarin in heparin-induced thrombocytopenia: an analysis of outcomes in patients with elevated international normalized ratio (INR)John R Bartholomew
Department of Cardiovascular Medicine and Hematology Oncology, Cleveland Clinic Foundation, 9500 Euclid Ave, S 60, Cleveland, OH, 44195, USA
J Thromb Thrombolysis 19:183-8. 2005..Because the clinical outcomes in patients achieving an INR > 4 during combined argatroban/warfarin therapies for HIT are not well described, we evaluated the clinical outcomes of 111 patients with this phenomenon... - Heparin-induced thrombocytopenia: principles for early recognition and managementJohn R Bartholomew
Section of Vascular Medicine, Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Cleve Clin J Med 72:S31-6. 2005..Once HIT is clinically suspected, heparin should be stopped immediately and direct thrombin inhibitor therapy started; waiting for laboratory confirmation may be catastrophic... - Varicose veins: newer, better treatments availableJohn R Bartholomew
Department of Cardiovascular Medicine, Section of Vascular Medicine, The Cleveland Clinic Foundation, OH, 44195, USA
Cleve Clin J Med 72:312-4, 319-21, 325-8. 2005.... - Transition to an oral anticoagulant in patients with heparin-induced thrombocytopeniaJohn R Bartholomew
Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, 9500 Euclid Ave, S 60, Cleveland, OH 44195, USA
Chest 127:27S-34S. 2005.... - Argatroban anticoagulation in intensive care patients: effects of heart failure and multiple organ system failureSusan M Begelman
Cleveland Clinic, Cleveland, Ohio, USA
J Intensive Care Med 23:313-20. 2008..Reduced doses are needed when heart failure or multiple organ system failure is present... - An algorithm for managing warfarin resistanceOlusegun Osinbowale
Department of Cardiovascular Medicine, Section of Vascular Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Cleve Clin J Med 76:724-30. 2009..This review offers an algorithm for the evaluation of patients with suspected warfarin resistance... - Rectus sheath hematomaOlusegun Osinbowale
Section of Vascular Medicine, Department of Cardiology Ochsner Clinic Foundation, New Orleans, LA 70121, USA
Vasc Med 13:275-9. 2008..Rectus sheath hematoma is not a contraindication to resuming anticoagulation once the hematoma has been adequately managed and the patient has returned to a stable clinical baseline... - Lepirudin anticoagulation for heparin-induced thrombocytopeniaSteven R Deitcher
Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Ohio 44195, USA
J Pediatr 140:264-6. 2002..Lepirudin, dosed in the recommended adult weight--based fashion, was an effective antithrombotic agent in pediatric patients with HIT... - Dabigatran: will it change clinical practice?Siddharth A Wartak
FACC, Department of Cardiovascular Medicine, Cleveland Clinic, OH 44195, USA
Cleve Clin J Med 78:657-64. 2011..However, it is more expensive, and this may limit its widespread use... - Combined effect of chronic kidney disease and peripheral arterial disease on all-cause mortality in a high-risk populationYin Ping Liew
Department of Nephrology and Hypertension, Cleveland Clinic, Cleveland, OH 44195, USA
Clin J Am Soc Nephrol 3:1084-9. 2008..It was hypothesized that the risk for death is higher in patients with both chronic kidney disease and peripheral arterial disease compared with those with chronic kidney disease or peripheral arterial disease alone... - Venous thromboembolism prophylaxis in hospitalized heart failure patientsPreeti Jois-Bilowich
Preeti Jois Bilowich, Department of Emergency Medicine, Desk E 19, The Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
J Card Fail 14:127-32. 2008..Our purpose was to describe the rate of use and the characteristics of patients receiving VTE prophylaxis in the Acute Decompensated Heart Failure National Registry (ADHERE)... - Patients with acute pulmonary embolism should have an echocardiogram to guide treatment decisionsAmjad Almahameed
Section of Vascular Medicine, Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, 9500 Euclid Avenue, S60, Cleveland, OH, USA
Med Clin North Am 87:1251-62. 2003..Pretest clinical suspicion for pulmonary embolism (PE) is high. Ventilation and perfusion lung scintigraphy are interpreted as being high-probability for PE. The nurse asks if a stat transthoracic echocardiogram should be ordered... - Air travel and venous thromboembolism: minimizing the riskJohn R Bartholomew
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, USA
Minn Med 94:43-9. 2011..The goal of this article is to provide an overview of how best to prevent VTE during travel, and how to diagnose and treat it... - Interpreting the JUPITER trial: statins can prevent VTE, but more study is neededAlejandro Perez
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA
Cleve Clin J Med 77:191-4. 2010.... - Warfarin-induced skin necrosis and venous limb gangrene in the setting of heparin-induced thrombocytopeniaAbhay F Srinivasan
Section of Hematology-Oncology, Department of Medicine, Baylor College of Medicine, Houston, Tex. 77030, USA
Arch Intern Med 164:66-70. 2004..Warfarin should be initiated at modest doses in patients with HIT after platelet recovery. Implications extend to warfarin initiation with other thrombotic diatheses...