Research Topics
| Amrita KrishnanSummaryAffiliation: City of Hope National Medical Center Country: USA Publications
| Collaborators
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Detail Information
Publications
Autologous stem cell transplantation for HIV-associated lymphomaA Krishnan
Division of Hematology and Bone Marrow Transplantation, City of Hope Medical Center, Duarte, California 91010, USA
Blood 98:3857-9. 2001..Prolonged lymphoma remissions, without significant compromise of immune function, can be seen, suggesting that ASCT can be used in selected patients with HIV-L...- Phase II trial of a transplantation regimen of yttrium-90 ibritumomab tiuxetan and high-dose chemotherapy in patients with non-Hodgkin's lymphomaAmrita Krishnan
Division of Hematology and Hematopoietic Cell Transplantation, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA
J Clin Oncol 26:90-5. 2008.... - Malignancies in women with HIV infectionAmrita Krishnan
City of Hope National Medical Center, 1500 East Duarte Road, Duarte, CA 91010, USA
Womens Health (Lond Engl) 4:357-68. 2008..The use of therapy has been associated with marked improvement in response rates and overall survival of affected patients... - Durable remissions with autologous stem cell transplantation for high-risk HIV-associated lymphomasAmrita Krishnan
City of Hope Hematologic Neoplasia Program, City of Hope Cancer Center, Duarte, CA 90101, USA
Blood 105:874-8. 2005..With long-term follow-up we demonstrate that ASCT can lead to an 85% progression-free survival, which suggests that this approach may be potentially curative in select patients with relapsed HIV-associated HD or NHL... - Stem cell transplantation in HIV-infected patientsAmrita Krishnan
City of Hope Medical Center, Department of Heme HCT, Duarte, California 91010, USA
Curr Opin HIV AIDS 4:11-5. 2009.... - Should HIV-positive patients with lymphoma be offered stem cell transplants?A Krishnan
Hematologic Neoplasia Program, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA
Bone Marrow Transplant 32:741-8. 2003..This suggests that patients with HIV-associated lymphomas should be considered for autologous transplantation in a manner similar to HIV-negative lymphoma patients... - HIV status does not affect the outcome of autologous stem cell transplantation (ASCT) for non-Hodgkin lymphoma (NHL)Amrita Krishnan
Department of Hematology Hematopoietic Cell Transplantation, City of Hope Cancer Center, 1500 East Duarte Road, Duarte, CA 91010, USA
Biol Blood Marrow Transplant 16:1302-8. 2010..These results provide further evidence that HIV status does not affect the long-term outcome of ASCT for NHL, and therefore HIV status alone should no longer exclude these patients from transplant clinical trials... - Hematopoietic stem cell transplantation for AIDS-related malignanciesAmrita Krishnan
Division of Hematology Hematopoietic Stem Cell Transplant, City of Hope Cancer Center, Duarte, California, USA
Curr Opin Oncol 22:456-60. 2010..The purpose of this article is to explore the transplant options for HIV-positive patients after widespread use of highly active antiretroviral therapy... - Stem cell transplantation and gene therapy for HIV-related lymphomasAmrita Krishnan
Division of Hematology and Bone Marrow Transplantation, and Department of Virology, City of Hope National Medical Center, Duarte, CA 91010, USA
J Hematother Stem Cell Res 11:765-75. 2002..Herein, we describe the use of high-dose chemotherapy with stem cell rescue in conjunction with current and future gene therapy approaches for the treatment of HIV-associated lymphomas... - Does follicularity in large cell lymphoma predict outcome after autologous stem cell transplantation?Amrita Krishnan
Division of Hematology Hematopoietic Cell Transplantation, City of Hope Comprehensive Cancer Center, Duarte, California 91010, USA
Biol Blood Marrow Transplant 12:641-7. 2006..Furthermore, the similar plateau in the survival curve for the DLCL and FLCL patients suggests that the behavior of FLCL is similar to that of DLCL and that FLCL is potentially curable with ASCT... - Comparison of reduced-intensity and conventional myeloablative regimens for allogeneic transplantation in non-Hodgkin's lymphomaRoberto Rodriguez
Hematology and Hematopoietic Cell Transplantation, City of Hope Comprehensive Cancer Center, Duarte, California 91001, USA
Biol Blood Marrow Transplant 12:1326-34. 2006.... - Tandem autologous stem cell transplantation for patients with primary refractory or poor risk recurrent Hodgkin lymphomaHenry C Fung
City of Hope Comprehensive Cancer Center, Hematology, Durante, California 91010, USA
Biol Blood Marrow Transplant 13:594-600. 2007..Our mature results from this study suggest that in patients with primary progressive or poor risk recurrent HL, this tandem ASCT program is effective and well tolerated and compares favorably with the conventional single transplant... - A phase 1/2 trial of high-dose yttrium-90-ibritumomab tiuxetan in combination with high-dose etoposide and cyclophosphamide followed by autologous stem cell transplantation in patients with poor-risk or relapsed non-Hodgkin lymphomaAuayporn Nademanee
Division of Hematology and Hemapoietic Cell Transplantation, City of Hope National Medical Center, 1500 E Duarte Rd, Duarte, CA 91010, USA
Blood 106:2896-902. 2005..We conclude that high-dose 90Y-ibritumomab tiuxetan can be combined safely with high-dose etoposide and cyclophosphamide without an increase in transplant-related toxicity or delayed engraftment... - Longitudinal assessment of hematopoietic abnormalities after autologous hematopoietic cell transplantation for lymphomaRavi Bhatia
Division of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA 91010, USA
J Clin Oncol 23:6699-711. 2005..The phenomenon of hematopoietic reconstitution after autologous HCT and the role of proliferative stress in the pathogenesis of t-MDS/AML are poorly understood... - Total marrow irradiation: a new ablative regimen as part of tandem autologous stem cell transplantation for patients with multiple myelomaGeorge Somlo
Departments of Medical Oncology and Therapeutics Research, City of Hope Cancer Center, Duarte, California 91010, USA
Clin Cancer Res 17:174-82. 2011..To establish feasibility, maximum tolerated dose (MTD), and potential efficacy of ablative dose total marrow irradiation (TMI) delivered by helical tomotherapy in patients with multiple myeloma (MM)... - Autologous haemopoietic stem-cell transplantation followed by allogeneic or autologous haemopoietic stem-cell transplantation in patients with multiple myeloma (BMT CTN 0102): a phase 3 biological assignment trialAmrita Krishnan
City of Hope Cancer Center, Los Angeles, CA, USA
Lancet Oncol 12:1195-203. 2011..Thus, we aimed to assess effectiveness of allogeneic HSCT with non-myeloablative conditioning after autologous HSCT compared with tandem autologous HSCT... - Interleukin-2 after autologous stem-cell transplantation for adult patients with acute myeloid leukemia in first complete remissionAnthony S Stein
Division of Hematology and Bone Marrow Transplantation, City of Hope National Medical Center, 1500 East Duarte Road, Duarte, CA 91010, USA
J Clin Oncol 21:615-23. 2003.... - Treatment of human immunodeficiency virus-related lymphoma with haematopoietic stem cell transplantationArturo Molina
Division of Hematology and Bone Marrow Transplantation and Department of Virology, City of Hope National Medical Center, Duarte, CA, USA
Blood Rev 17:249-58. 2003..e., two or three of the following: elevated LDH, advanced stage, and poor performance status). Acquisition of resistance to HAART remains as a potential problem for HIV-positive patients who are cured of their lymphoma... - Efficacy of mycophenolate mofetil in the treatment of chronic graft-versus-host diseaseFrancisco Lopez
Division of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, California 91010, USA
Biol Blood Marrow Transplant 11:307-13. 2005..These data suggest that MMF is an active, well-tolerated agent in the treatment of cGVHD and may have a beneficial effect on the survival of patients with this complication... - Matched-Cohort Analysis of Autologous Hematopoietic Cell Transplantation with Radioimmunotherapy versus Total Body Irradiation-Based Conditioning for Poor-Risk Diffuse Large Cell LymphomaAmrita Krishnan
Department of Hematology Hematopoietic Cell Transplantation, City of Hope, Duarte, California
Biol Blood Marrow Transplant 18:441-50. 2012..8% for TBI at 4 years (P < .01). Our data demonstrate that RIT-based conditioning had a similar relapse incidence to TBI, with lower toxicity, resulting in improved overall survival, particularly in patients with ?2 prior regimens... - RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphomaDavid L Digiusto
Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA 91010, USA
Sci Transl Med 2:36ra43. 2010..These results support the development of an RNA-based cell therapy platform for HIV... - Organ transplantation in HIV-infected patientsAmrita Krishnan
N Engl J Med 347:1801-3; author reply 1801-3. 2002 - Use of radioimmunotherapy in stem cell transplantation and posttransplantation: focus on yttrium 90 ibritumomab tiuxetanArturo Molina
Biogen Idec Inc, San Diego, CA 92122, USA
Curr Stem Cell Res Ther 2:239-48. 2007..Studies of (90)Y ibritumomab tiuxetan in the setting of allogeneic stem cell transplantation appear promising as well... - Multicenter phase II study of bortezomib in patients with relapsed or refractory mantle cell lymphomaRichard I Fisher
University of Rochester, James P Wilmot Cancer Center, Rochester, USA
J Clin Oncol 24:4867-74. 2006..Evaluate response rate, duration of response (DOR), time-to-progression (TTP), overall survival (OS), and safety of bortezomib treatment in patients with relapsed or refractory mantle cell lymphoma (MCL)...