Research Topics
| Maria KnikouSummaryAffiliation: City University of New York Country: USA Publications
Research Grants
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Detail Information
Publications
The H-reflex as a probe: pathways and pitfallsMaria Knikou
Health Sciences Doctoral Programs, City University of New York, Staten Island, NY 10314, USA
J Neurosci Methods 171:1-12. 2008..If these limitations are recognized and addressed, the H-reflex constitutes one of the major probes to assess excitability of interneuronal circuits at rest and during movement in humans...- Soleus H-reflex excitability changes in response to sinusoidal hip stretches in the injured human spinal cordMaria Knikou
Sensory Motor Performance Program, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
Neurosci Lett 423:18-23. 2007..This will aid in the development of rehabilitation strategies to restore motor function in these patients... - Flexion reflex modulation during stepping in human spinal cord injuryMaria Knikou
Health Sciences Doctoral Programs, The Graduate Center, City University of New York, 2800 Victory Boulevard, Staten Island, NY 10314, USA
Exp Brain Res 196:341-51. 2009..in Exp Brain Res 193:397-407, 2009). We propose that training should selectively target spinal reflex circuits in which extensor muscles and reflexes are involved in order to maximize sensorimotor recovery in these patients... - Parallel facilitatory reflex pathways from the foot and hip to flexors and extensors in the injured human spinal cordMaria Knikou
Sensory Motor Performance Program, Rehabilitation Institute of Chicago, and Department of Physical Medicine and Rehabilitation, Feinberg Medical School, Northwestern University, Chicago, IL 60611, USA
Exp Neurol 206:146-58. 2007..The interactive effects of these sensory signals may be a feature of impaired gait, but when they are appropriately excited, they may contribute to locomotion recovery in these patients... - Neural coupling between the upper and lower limbs in humansMaria Knikou
Department of Physical Therapy and Neuroscience, The Graduate Center, City University of New York, Staten Island, NY 10314, USA
Neurosci Lett 416:138-43. 2007.... - Hip-phase-dependent flexion reflex modulation and expression of spasms in patients with spinal cord injuryMaria Knikou
Sensory Motor Performance Program, Rehabilitation Institute of Chicago, Chicago, IL 60610, USA
Exp Neurol 204:171-81. 2007.... - Effects of changes in hip position on actions of spinal inhibitory interneurons in humansMaria Knikou
Sensory Motor Performance Program, Rehabilitation Institute of Chicago and The Feinberg School of Medicine, Department of Physical Medicine and Rehabilitation, Northwestern University, Ilinois, USA
Int J Neurosci 116:945-61. 2006..This neural switch might constitute an important feature of movement regulation in humans... - On the methods employed to record and measure the human soleus H-reflexMaria Knikou
Department of Rehabilitation Medicine, Staten Island University Hospital, Staten Island, NY 10314, USA
Somatosens Mot Res 23:55-62. 2006..The implications of our findings are discussed in respect to human reflex studies... - Pre- and post-alpha motoneuronal control of the soleus H-reflex during sinusoidal hip movements in human spinal cord injuryMaria Knikou
Department of Biology and Physical Therapy, City University of New York, Staten Island, NY 10314, USA
Brain Res 1103:123-39. 2006..The expression of these spinal interneuronal circuits during imposed sinusoidal hip movements is discussed with respect to motor recovery in humans after SCI... - Modulation of flexion reflex induced by hip angle changes in human spinal cord injuryMaria Knikou
Sensory Motor Performance Program, Rehabilitation Institute of Chicago, IL, USA
Exp Brain Res 168:577-86. 2006..The sensory consequences of this afferent input should be considered in rehabilitation programs aimed to restore movement and sensorimotor function in these patients... - Soleus H-reflex gain, threshold, and amplitude as function of body posture and load in spinal cord intact and injured subjectsMaria Knikou
Health Science Doctoral Programs, City University of New York, Staten Island, New York 10314, USA
Int J Neurosci 119:2056-73. 2009..Impaired spinal reflex excitability in SCI subjects is accompanied by changes of the H-reflex recruitment curve parameters regardless of presence or absence of body loading... - Soleus H-reflex modulation during body weight support treadmill walking in spinal cord intact and injured subjectsMaria Knikou
Health Science Doctoral Programs, The Graduate Center, City University of New York, Staten Island, NY 10314, USA
Exp Brain Res 193:397-407. 2009..The reflex gain was similar for both subject groups, but the y-intercept was increased in SCI subjects. We conclude that the mechanisms underlying cyclic H-reflex modulation during walking are preserved in some individuals after SCI... - Soleus H-reflex graded depression by contralateral hip afferent feedback in humansVimal Stanislaus
Northwestern University Feinberg School of Medicine, Chicago, IL, USA
Brain Res 1310:77-86. 2010.... - Effects of hip joint angle changes on intersegmental spinal coupling in human spinal cord injuryMaria Knikou
Sensory Motor Performance Program, Rehabilitation Institute of Chicago, The Feinberg School of Medicine, Department of Physical Medicine and Rehabilitation, Northwestern University, Chicago, IL 60611, USA
Exp Brain Res 167:381-93. 2005.... - Hip angle induced modulation of H reflex amplitude, latency and duration in spinal cord injured humansMaria Knikou
Department of Physical Medicine and Rehabilitation, Feinberg School of Medicine, Northwestern University, 345 East Superior, Room 1406, Chicago, IL 60611, USA
Clin Neurophysiol 113:1698-708. 2002.... - Soleus H-reflex phase-dependent modulation is preserved during stepping within a robotic exoskeletonMaria Knikou
Sensory Motor Performance Program, Rehabilitation Institute of Chicago, Chicago, IL, USA
Clin Neurophysiol 122:1396-404. 2011.... - Neural control of locomotion and training-induced plasticity after spinal and cerebral lesionsMaria Knikou
Health Science Doctoral Programs, City University of New York, Staten Island, NY 10314, USA
Clin Neurophysiol 121:1655-68. 2010..For maximizing sensorimotor recovery in people with spinal or cerebral lesions, a multidisciplinary approach (rehabilitation, pharmacology, and electrical stimulation) delivered during various sensorimotor constraints is needed... - Plantar cutaneous afferents normalize the reflex modulation patterns during stepping in chronic human spinal cord injuryMaria Knikou
Health Sciences Doctoral Programs, The Graduate Center, City University of New York, 2800 Victory Boulevard, 5N 207, Staten Island, NY 10314, USA
J Neurophysiol 103:1304-14. 2010.... - Static and dynamic changes in body orientation modulate spinal reflex excitability in humansMaria Knikou
Feinberg School of Medicine, Northwestern University, 345 East Superior, Chicago, IL 60611, USA
Exp Brain Res 152:466-75. 2003..In addition, they highlight the potent modulatory effects that natural stimulation of the vestibular system can have on reflex excitability. The implications of our findings are discussed in relation to the maintenance of body posture... - Effects of changes in hip joint angle on H-reflex excitability in humansMaria Knikou
Sensory Motor Performance Program, Northwestern University Medical School, Department of Physical Medicine and Rehabilitation, Rehabilitation Institute of Chicago, Room 1406, 345 East Superior, Chicago, IL 60611, USA
Exp Brain Res 143:149-59. 2002..The origins of such a spinal mechanism are discussed... - Reduced reciprocal inhibition during assisted stepping in human spinal cord injuryMaria Knikou
The Graduate Center, City University of New York College of Staten Island, Staten Island, NY 10314, USA
Exp Neurol 231:104-12. 2011..Based on these findings, we suggest that rehabilitation should selectively target to transform reciprocal facilitation to inhibition through computer controlled reflex conditioning protocols... - Soleus H-reflex phase-dependent modulation during one-legged foot reaching and withdrawal in standing humansMaria Knikou
City University of New York, Staten Island, New York, NY 10314, United States
Neurosci Lett 487:305-9. 2011..This study provides evidence that the soleus H-reflex is modulated in a phasic pattern during one-legged foot reaching and withdrawal by changes occurring at a premotoneuronal level... - The action of plantar pressure on flexion reflex pathways in the isolated human spinal cordBernard A Conway
Bioengineering Unit, University of Strathclyde, Glasgow G4 0NW, Scotland, UK
Clin Neurophysiol 119:892-6. 2008..To investigate the conditioning effects of plantar pressure on flexion reflex excitability in patients with motor complete spinal cord injury (SCI)... - Reflex effects of induced muscle contraction in normal and spinal cord injured subjectsMaria Knikou
Bioengineering Unit, University of Strathclyde, Glasgow G4 0NW, Scotland, UK
Muscle Nerve 26:374-82. 2002....
Research Grants
- Neurophysiological mechanisms underlying spasms in SCIMaria Knikou; Fiscal Year: 2004..A future study can be concentrated on the potential reflex pathways underlying spasms and their relation to hip extension (end of stance phase) during assisted locomotion in incomplete SCI patients. ..