Research TopicsGenomes and GenesSpecies | Irene E ZohnSummaryAffiliation: Children's National Medical Center Country: USA Publications
Research Grants
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Publications
Transformation by a nucleotide-activated P2Y receptor is mediated by activation of Galphai, Galphaq and Rho-dependent signaling pathwaysAnurag Singh
Linebergher Comprehensive Cancer Center, University of North Carolina at Chapel Hill, NC 27599, USA
J Mol Signal 5:11. 2010..Nucleotide-actived P2Y receptors play critical roles in the growth of tumor cells by regulating cellular proliferation, differentiation and survival...
The visceral yolk sac endoderm provides for absorption of nutrients to the embryo during neurulationIrene E Zohn
Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
Birth Defects Res A Clin Mol Teratol 88:593-600. 2010....
The iron exporter ferroportin 1 is essential for development of the mouse embryo, forebrain patterning and neural tube closureJinzhe Mao
Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
Development 137:3079-88. 2010..Finally, we demonstrate that this loss of forebrain maintenance is due in part to the iron deficiency that results from the absence of fully functional Fpn1...
Hectd1 regulates intracellular localization and secretion of Hsp90 to control cellular behavior of the cranial mesenchymeAnjali A Sarkar
Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
J Cell Biol 196:789-800. 2012....
Modeling neural tube defects in the mouseIrene E Zohn
Children s Research Institute, Children s National Medical Center, Washington, DC, USA
Curr Top Dev Biol 84:1-35. 2008..In some cases these studies have led to development of approaches to prevent NTDs and provide an understanding of the underlying molecular mechanism of these therapies prevent NTDs...
Research Grants
- Novel Ubiquitin Dependent Pathways Regulating Neural Tube Closure and PlacentatioIrene E Zohn; Fiscal Year: 2010..The understanding gained from the experiments proposed here may lead to strategies to minimize these complications of pregnancy. ..
