Research Topics
| Michael D GreenSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
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Detail Information
Publications
In vivo efficacy of artemether-lumefantrine against uncomplicated Plasmodium falciparum malaria in Central EthiopiaJimee Hwang
U S Centers for Disease Control and Prevention, Atlanta, GA, USA
Malar J 10:209. 2011..In Ethiopia, artemether-lumefantrine (AL) has been the first-line treatment for uncomplicated P. falciparum malaria since 2004...
Determination of oseltamivir quality by colorimetric and liquid chromatographic methodsMichael D Green
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Emerg Infect Dis 14:552-6. 2008..The Congo red test showed greater assay sensitivity, linearity, and accuracy. Colorimetric and chromatographic analysis showed all batches of oseltamivir product were within +/-15% of the stated amount of active ingredient...
Pharmacokinetics of sulfadoxine-pyrimethamine in HIV-infected and uninfected pregnant women in Western KenyaMichael D Green
Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Infect Dis 196:1403-8. 2007..We investigated whether this reflects their impaired immunity or an HIV-associated alteration in the disposition of SP...
Antimalarial drug resistance and the importance of drug quality monitoringM D Green
Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
J Postgrad Med 52:288-90. 2006..This report describes the importance of drug quality monitoring as part of a comprehensive disease surveillance program...
Use of refractometry and colorimetry as field methods to rapidly assess antimalarial drug qualityMichael D Green
Division of Parasitic Diseases, US Centers for Disease Control and Prevention, Atlanta, GA, United States
J Pharm Biomed Anal 43:105-10. 2007..78 for enterically coated chloroquine tablets. These techniques provide a generally accurate, yet simple and affordable means to assess drug quality in resource-poor settings...
Direct quantitation of active ingredients in solid artesunate antimalarials by noncovalent complex forming reactive desorption electrospray ionization mass spectrometryLeonard Nyadong
School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332 0400, USA
J Am Soc Mass Spectrom 19:380-8. 2008..9985). Application of this method to the direct quantitation of genuine artesunate tablets from Vietnam showed a 6% (n = 4) precision and 94% accuracy after the spectral data were corrected for tablet hardness...
Characterization of counterfeit artesunate antimalarial tablets from southeast AsiaKrystyn Alter Hall
School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, USA
Am J Trop Med Hyg 75:804-11. 2006....
Poor quality drugs: grand challenges in high throughput detection, countrywide sampling, and forensics in developing countriesFacundo M Fernandez
School of Chemistry and Biochemistry, Georgia Institute of Technology, 901 Atlantic Drive NW, Atlanta, GA 30332 0400, USA
Analyst 136:3073-82. 2011....
Reactive desorption electrospray ionization linear ion trap mass spectrometry of latest-generation counterfeit antimalarials via noncovalent complex formationLeonard Nyadong
School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, USA
Anal Chem 79:2150-7. 2007..Of particular concern was the positive detection of artesunate traces in the surface of one of the samples, which we quantified with standard chromatographic techniques...
High-performance liquid chromatographic assay for the simultaneous determination of sulfadoxine and pyrimethamine from whole blood dried onto filter paperMichael D Green
Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, Atlanta, GA 30333, USA
J Chromatogr B Analyt Technol Biomed Life Sci 767:159-62. 2002..Extraction recoveries are about 60% for both drugs. The coefficient of variation for intra-assay precision, inter-assay precision and accuracy is less than 10% for sulfadoxine (10-100 microg/ml) and pyrimethamine (1-10 microg/ml)...
Transmission-mode direct analysis in real time and desorption electrospray ionization mass spectrometry of insecticide-treated bednets for malaria controlJose J Perez
School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332, USA
Analyst 135:712-9. 2010..Transmission-mode desorption electrospray ionization (TM-DESI) experiments on similar insecticide-treated nets were performed for comparison purposes...
Efficacy of mefloquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum infection in Machinga District, Malawi, 1998J MacArthur
Malaria Epidemiology Branch, Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3717, USA
Am J Trop Med Hyg 65:679-84. 2001....
A colorimetric field method to assess the authenticity of drugs sold as the antimalarial artesunateM D Green
Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Pharm Biomed Anal 24:65-70. 2000..The average amount of artesunate in the genuine tablets was determined to be 50.8 +/- 2.9 mg while the counterfeit tablets were found to contain no artesunate...
Authentication of artemether, artesunate and dihydroartemisinin antimalarial tablets using a simple colorimetric methodM D Green
Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Trop Med Int Health 6:980-2. 2001..The colorimetric method can be used to obtain a rapid visual assessment of tablet authenticity. The method can also be used to quantify the drug content of tablets, when used in conjunction with a spectrophotometer...
Formation of hydroxyeicosatetraenoic acids from hemozoin-catalyzed oxidation of arachidonic acidM D Green
Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Mol Biochem Parasitol 83:183-8. 1996..Since HETEs are important vasoactive mediators, the non-enzymatic oxidation of arachidonic acid by hemozoin catalysis may contribute to some of the pathophysiology associated with severe and cerebral malaria...
Improved validated assay for the determination of mefloquine and its carboxy metabolite in plasma, serum and whole blood using solid-phase extraction and high-performance liquid chromatographyM D Green
Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, Atlanta, GA 30333, USA
J Chromatogr B Biomed Sci Appl 727:159-65. 1999..This method shows a robust analytical procedure for the simultaneous analysis of mefloquine and its carboxy metabolite where precise measurements are useful in pharmacokinetic studies and in estimating drug compliance...
Desorption electrospray ionization reactions between host crown ethers and the influenza neuraminidase inhibitor oseltamivir for the rapid screening of TamifluLeonard Nyadong
School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332, USA
Analyst 133:1513-22. 2008..These competitive reactions were then successfully tested as a means for the rapid quantitation of oseltamivir by reactive DESI MS without the need for an internal standard...
Rapid colorimetric field test to determine levels of deltamethrin on PermaNet surfaces: association with mosquito bioactivityMichael D Green
Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
Trop Med Int Health 14:381-8. 2009..To evaluate a simple and inexpensive colorimetric test to measure the amount of cyanopyrethroid insecticide residue from filter paper exposed to mosquito net surfaces...
Chemiluminescent detection of artemisinin. Novel endoperoxide analysis using luminol without hydrogen peroxideM D Green
Entomology Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, US Department of Health and Human Services, Atlanta, GA 30333, USA
J Chromatogr A 695:237-42. 1995..Since H2O2 is not needed in the analysis, the endoperoxide moiety on artemisinin is implicated as a contributing source of superoxide radicals required for the light-producing reaction with luminol...
In vitro and in vivo evaluation of albumin-encapsulated primaquine diphosphate prepared by nebulization into heated oilM D Green
Division of Parasitic Diseases, National Center of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Microencapsul 21:433-44. 2004..8x), lower steady-state volume of distribution (10x) and slower half-life (2.5x) relative to an equivalent dose of free primaquine diphosphate suggest liver targeting and sustained release of the drug from the microparticles...
A collaborative epidemiological investigation into the criminal fake artesunate trade in South East AsiaPaul N Newton
Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Churchill Hospital, Oxford, United Kingdom
PLoS Med 5:e32. 2008....
Manslaughter by fake artesunate in Asia--will Africa be next?Paul N Newton
Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Churchill Hospital, Oxford, United Kingdom
PLoS Med 3:e197. 2006
Counterfeit artemisinin derivatives and Africa: update from authorsPaul N Newton
PLoS Med 4:e139. 2007
Impaired clinical response in a patient with uncomplicated falciparum malaria who received poor-quality and underdosed intramuscular artemetherValy Keoluangkhot
Adult Infectious Disease Ward, Mahosot Hospital, Vientiane, Lao PDR
Am J Trop Med Hyg 78:552-5. 2008..Analysis of the packaging and chemical "fingerprinting" of the artemether suggested that the drug was genuine but was either substandard or had deteriorated after manufacture...
Chloroquine enhances survival in Bacillus anthracis intoxicationAndrew W Artenstein
Center for Biodefense and Emerging Pathogens, Division of Infectious Diseases, Memorial Hospital of Rhode Island, Pawtucket 02860, USA
J Infect Dis 190:1655-60. 2004..CQ significantly enhanced survival and may augment current treatment and prophylaxis options for this otherwise lethal infection...
Quantitative viral load monitoring and cidofovir therapy for the management of BK virus-associated nephropathy in children and adultsAbhay Vats
Department of Pediatrics, Children s Hospital of Pittsburgh, Pittsburgh, PA 15213, USA
Transplantation 75:105-12. 2003..BK virus (BKV)-associated nephropathy (BKVAN) has been increasingly recognized as an important cause of renal transplant dysfunction. We report the role of quantitative viral load monitoring in the management of BKVAN...
