Research Topics
Genomes and GenesSpecies | Cheng Yen ChenSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
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Detail Information
Publications
A real-time quadriplex PCR assay for the diagnosis of rectal lymphogranuloma venereum and non-lymphogranuloma venereum Chlamydia trachomatis infectionsC Y Chen
Division of STD Prevention, National Center for HIV AIDS, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Mail Stop G 39, 1600 Clifton Road, Atlanta, GA 30333, USA
Sex Transm Infect 84:273-6. 2008..To develop and evaluate a real-time quadriplex PCR for the diagnosis of lymphogranuloma venereum (LGV) and non-LGV chlamydial infections using rectal swab specimens...- The molecular diagnosis of lymphogranuloma venereum: evaluation of a real-time multiplex polymerase chain reaction test using rectal and urethral specimensCheng Yen Chen
Division of STD Prevention, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Sex Transm Dis 34:451-5. 2007.... - Diagnosis of gastric syphilis by direct immunofluorescence staining and real-time PCR testingCheng Yen Chen
Division of STD Prevention, National Center for HIV, STD and TB Prevention, Centers for Disease Control and Prevention, Mail Stop G 39, 1600 Clifton Road, Atlanta, GA 30333, USA
J Clin Microbiol 44:3452-6. 2006.... - Neisseria gonorrhoeae bacterioferritin: structural heterogeneity, involvement in iron storage and protection against oxidative stressC Y Chen
Division of AIDS, Sexually Transmitted Diseases and Tuberculosis Laboratory Research, National Centers for Infectious Disease, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Microbiology 145:2967-75. 1999..These results demonstrate that gonococcal Bfr plays an important role in iron storage and protection from iron-mediated oxidative stress... - Laboratory-confirmed case of yaws in a 10-year-old boy from the Republic of the CongoAllan Pillay
Laboratory Reference and Research Branch, Division of Sexually Transmitted Disease Prevention, NCHHSTP, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Clin Microbiol 49:4013-5. 2011..This is the first report describing the use of DNA sequencing to identify Treponema pallidum subsp. pertenue-specific sequences in a patient with active yaws... - Cloning, sequencing and expression of a cDNA encoding bovine pancreatic deoxyribonuclease I in Escherichia coli: purification and characterization of the recombinant enzymeC Y Chen
Institute of Biochemistry, College of Medicine, National Taiwan University, No 1, Sec 1, Jen Ai Road, Taipei, Taiwan, People s Republic of China
Gene 206:181-4. 1998..The NH2-terminus of rb-DNase I was Ala, not Met, and at position 19, corresponding to the carbohydrate attachment site of bp-DNase I, Asn was not glycosylated... - Expression of a functional neisserial fbp gene in Escherichia coliS A Berish
Division of Sexually Transmitted Diseases Laboratory Research, Centers for Disease Control, Atlanta, Georgia 30333
Mol Microbiol 6:2607-15. 1992..Both fusion clones produced Fbp in large amounts, facilitating the purification of quantities of Fbp sufficient for elucidating the biochemical, immunologic, and functional properties of this protein... - Molecular typing of Treponema pallidum in South Africa: cross-sectional studiesA Pillay
Centers for Disease Control and Prevention, Atlanta, Georgia 303333, USA
J Clin Microbiol 40:256-8. 2002..The unique subtypes identified in Durban, Cape Town, and Carletonville and the total number of subtypes suggested that the strain population was very diverse and varied geographically... - Increasing relative prevalence of HSV-2 infection among men with genital ulcers from a mining community in South AfricaW Lai
Department of Dermatology, Third Affiliated Hospital, Sun Yat-sen University of Medical Sciences, Guangzhou, P R China
Sex Transm Infect 79:202-7. 2003..No association was found between HIV infection status and the relative prevalence of chancroid or syphilis... - SlyA, a transcriptional regulator of Salmonella typhimurium, is required for resistance to oxidative stress and is expressed in the intracellular environment of macrophagesN Buchmeier
Department of Pathology, University of California, San Diego, La Jolla 92093 0640, USA
Infect Immun 65:3725-30. 1997..These results suggest that the SlyA regulon is activated during infection of the host and is required for resistance to toxic oxidative products of the reticuloendothelial system... - Transcriptional regulation of a mouse Clara cell-specific protein (mCC10) gene by the NKx transcription factor family members thyroid transciption factor 1 and cardiac muscle-specific homeobox protein (CSX)M K Ray
Department of Cell Biology, Baylor College of Medicine, Houston, Texas 77030, USA
Mol Cell Biol 16:2056-64. 1996..This report emphasizes the importance of TTF1 or related factors as major regulators of pulmonary gene expression and demonstrates the potential of NKx proteins to bind and activate heterologous target genes... - Plasmid virulence gene expression induced by short-chain fatty acids in Salmonella dublin: identification of rpoS-dependent and rpo-S-independent mechanismsA El-Gedaily
Department of Medicine, University Hospital of Zurich, Switzerland
J Bacteriol 179:1409-12. 1997..During this fatty acid-mediated expression of spv, RpoS is required for induction only during exponential phase. In stationary phase, an rpoS-independent mechanism is responsible for expression of spv... - AU binding proteins recruit the exosome to degrade ARE-containing mRNAsC Y Chen
Department of Pharmacology, Laboratory of Gene Regulation and Signal Transduction, University of California, San Diego, La Jolla, CA 92093, USA
Cell 107:451-64. 2001..The mammalian exosome does not recognize ARE-containing RNAs on its own. ARE recognition requires certain ARE binding proteins that can interact with the exosome and recruit it to unstable RNAs, thereby promoting their rapid degradation... - Saccharomyces cerevisiae PKC1 encodes a protein kinase C (PKC) homolog with a substrate specificity similar to that of mammalian PKCM Watanabe
Department of Biochemistry, Johns Hopkins University, School of Public Health, Baltimore, Maryland 21205
J Biol Chem 269:16829-36. 1994.... - Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigenM L Smith
Laboratory of Molecular Pharmacology, National Cancer Institute, Bethesda, MD 20892
Science 266:1376-80. 1994..Gadd45 stimulated DNA excision repair in vitro and inhibited entry of cells into S phase. These results establish GADD45 as a link between the p53-dependent cell cycle checkpoint and DNA repair... - Degradation of azo dyes using low iron concentration of Fenton and Fenton-like systemC L Hsueh
Department of Chemical Engineering, National Cheng Kung University, Tainan City 701, Taiwan
Chemosphere 58:1409-14. 2005..High levels of H2O2 appear to reduce dye decolorization. In addition, it is also found that decolorization of azo dyes undergoes a faster reaction rate than mineralization of azo dyes... - Photooxidation of azo dye reactive black 5 using a novel supported iron oxide: heterogeneous and homogeneous approachC L Hsueh
Department of Chemical Engineering, National Cheng Kung University, Tainan City, 701 Taiwan
Water Sci Technol 53:195-201. 2006..5-6.0, the homogeneous catalysis is of increasing importance below pH 4.0 because of the Fe ions leaching from the catalyst to solution... - Characterization of human Gadd45, a p53-regulated proteinF Carrier
Laboratory of Molecular Pharmacology, DTP, DCT, NCI, National Institutes of Health, Bethesda, Maryland 20892
J Biol Chem 269:32672-7. 1994..These results indicate that some cell line(s) can tolerate high levels of Gadd45 and abrogate its growth suppression function... - The interaction of trichloroethanol with murine recombinant 5-HT3 receptorsD L Downie
Department of Pharmacology and Clinical Pharmacology, Ninewells Hospital and Medical School, University of Dundee
Br J Pharmacol 114:1641-51. 1995.... - Heterogeneous catalytic oxidation of hypophosphite by H2O2: pH effectC C Hung
Department of Chemical Engineering, National Cheng Kung University, Tainan City 701, Chinese Taiwan
Water Sci Technol 55:89-93. 2007..0 than that at pH 2.5. We conclude that it is a major heterogeneous catalytic oxidation by our novel iron oxide catalyst to oxidise HP at pH 4.0. Also, B1 could be a useful and potential catalyst for the treatment of HP wastewater... - Identification of multiple nuclear factors that interact with cyclic adenosine 3',5'-monophosphate response element-binding protein and activating transcription factor-2 by protein-protein interactionsJ P Hoeffler
Division of Medical Oncology, University of Colorado Cancer Center, Denver 80262
Mol Endocrinol 5:256-66. 1991..The identification and characterization of the components of eukaryotic transcription complexes will allow studies that address the molecular mechanisms of normal and abnormal control of cellular gene expression... - Versatile role for hnRNP D isoforms in the differential regulation of cytoplasmic mRNA turnoverN Xu
Department of Biochemistry and Molecular Biology, The University of Texas Houston Medical School, Houston, Texas 77030, USA
Mol Cell Biol 21:6960-71. 2001..Our results support the notion that hnRNP D serves as a key factor broadly involved in general mRNA decay... - Hydroxychloroquine sulphate inhibits in vitro apoptosis of circulating lymphocytes in patients with systemic lupus erythematosusS T Liu
Department of Internal Medicine, En Chu Kong Hospital, Taipei and Tainan, ROC
Asian Pac J Allergy Immunol 19:29-35. 2001..We propose that this results in decreased stimulation of autoreactive lymphocytes reactive with self-peptides, and consequently diminution of activation-induced cell death (apoptosis) of mature peripheral lymphocytes... - Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcriptionC Y Chen
Department of Cell Biology, Baylor College of Medicine, Houston, Texas 77030, USA
Mol Cell Biol 16:6372-84. 1996..5 homeodomain and to the N-terminal extension of the MADS box. Our study suggests that physical association between Nkx-2.5 and SRF is one way that cardiac specified genes are activated in cardiac cell lineages... - Replication focus-forming activity 1 and the Werner syndrome gene productH Yan
Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
Nat Genet 19:375-8. 1998..Here we report that FFA-1 has DNA-helicase activity. Moreover, it is a homologue of the human Werner syndrome gene product WRN, a protein associated with premature ageing in humans... - Identification of a novel beta-lactamase produced by Xanthomonas campestris, a phytopathogenic bacteriumS F Weng
Institute of Molecular Biology, National Chung Hsing University, Taichung 402, Taiwan, Republic of China
Antimicrob Agents Chemother 43:1792-7. 1999..Southern hybridization detected a single homologous fragment in each of 12 other Xanthomonas strains, indicating that the presence of a beta-lactamase gene is common among xanthomonads... - A novel clathrin homolog that co-distributes with cytoskeletal components functions in the trans-Golgi networkS H Liu
The G.W.Hooper Foundation, Department of Microbiology, University of California, San Francisco, CA 94143-0552, USA
EMBO J 20:272-84. 2001..Overexpression of a subdomain of CHC22 induces altered distribution of TGN markers. Together these results implicate CHC22 in TGN membrane traffic involving the cytoskeleton... - The p53 signal transduction pathway is intact in human neuroblastoma despite cytoplasmic localizationS C Goldman
Johns Hopkins Oncology Center, Baltimore, Maryland, USA
Am J Pathol 148:1381-5. 1996.... - A common precursor for the three subunits of L-glutamate oxidase encoded by gox gene from Streptomyces platensis NTU3304C Y Chen
Institute of Agricultural Chemistry, National Taiwan University, Republic of China
Can J Microbiol 47:269-75. 2001..The presence of the flavin adenine dinucleotide (FAD)-binding motif place Gox as a member of the flavoenzyme family. Furthermore, a negative effect of glucose on the biosynthesis of Gox was observed when it was used as carbon source... - An efficient method for the culture of Helicobacter pylori from gastric biopsies with two-section petri dishesH J Ding
School of Technology for Medical Sciences, Kaohsiung Medical University, Kaohsiung City, Taiwan
J Gastroenterol 36:237-41. 2001..1 +/- 0.3)%. CONCLUSIONS: According to Ansorg's method, the best detection rate (98.4 +/- 0.7)% could be obtained with two-section petri dishes which had 5% modified chocolate agar with antibiotics and the other without antibiotics... - Expression in Pichia pastoris and characterization by circular dichroism and NMR of rhodostominR T Guo
Department of Biochemistry, National Cheng Kung University Medical College, Tainan, Taiwan
Proteins 43:499-508. 2001..pastoris with the correct fold. This evidence may serve as the basis for exploring the structure and function relationships as well as the dynamics of disintegrin and its variants... - Expression of oncogene products HER2/Neu and Ras and fibrosis-related growth factors bFGF, TGF-beta, and PDGF in bile from biliary malignancies and inflammatory disordersW C Su
Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan
Dig Dis Sci 46:1387-92. 2001..The results suggest overexpression of bFGF, PDGF, and HER2/Neu and the presence of K-ras mutation are important for carcinogenesis of bile duct cancers, and detection of the above abnormalities in bile is helpful for early diagnosis... - The association of human papillomavirus 16/18 infection with lung cancer among nonsmoking Taiwanese womenY W Cheng
Institute of Medicine, Chung Shan Medical and Dental College, Taichung, Taiwan, Republic of China
Cancer Res 61:2799-803. 2001..The high prevalence of HPV 16/18 infection may explain to a certain extent why Taiwanese women nonsmokers had a higher lung cancer mortality rate...