N L Reinsmoen

Summary

Affiliation: Cedars-Sinai Medical Center
Country: USA

Publications

  1. ncbi Acceptable donor-specific antibody levels allowing for successful deceased and living donor kidney transplantation after desensitization therapy
    Nancy L Reinsmoen
    HLA Laboratory, Cedars Sinai Medical Center, 8723 Alden Drive, SSB 197, Los Angeles, CA 90048, USA
    Transplantation 86:820-5. 2008
  2. ncbi Pretransplant donor-specific and non-specific immune parameters associated with early acute rejection
    Nancy L Reinsmoen
    David Geffen School of Medicine at UCLA, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Transplantation 85:462-70. 2008
  3. ncbi Anti-angiotensin type 1 receptor antibodies associated with antibody mediated rejection in donor HLA antibody negative patients
    Nancy L Reinsmoen
    Cedars Sinai Medical Center, HLA Laboratory, Comprehensive Transplant Center, Los Angeles, CA 90048, USA
    Transplantation 90:1473-7. 2010
  4. ncbi A new era for T-cell immune function assays in transplantation
    N L Reinsmoen
    Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Tissue Antigens 75:658-67. 2010
  5. ncbi Calculated PRA: initial results show benefits for sensitized patients and a reduction in positive crossmatches
    J M Cecka
    UCLA Immunogenetics Center, Department of Pathology, University of California Los Angeles, Los Angeles, CA, USA
    Am J Transplant 11:719-24. 2011
  6. ncbi Rituximab and intravenous immune globulin for desensitization during renal transplantation
    Ashley A Vo
    Comprehensive Transplant Center, Transplant Immunology Laboratory, Cedars Sinai Medical Center, Los Angeles 90048, USA
    N Engl J Med 359:242-51. 2008
  7. ncbi Use of intravenous immune globulin and rituximab for desensitization of highly HLA-sensitized patients awaiting kidney transplantation
    Ashley A Vo
    Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Transplantation 89:1095-102. 2010
  8. ncbi Acute antibody-mediated rejection of cardiac transplants
    Elaine F Reed
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, 1000 Veteran Avenue, Room 1335, Los Angeles, CA 90095, USA
    J Heart Lung Transplant 25:153-9. 2006
  9. ncbi Pre-transplant panel reactive antibody in lung transplant recipients is associated with significantly worse post-transplant survival in a multicenter study
    Denis Hadjiliadis
    Department of Medicine, Division of Respirology, Toronto General Hospital, Toronto, Ontario, Canada
    J Heart Lung Transplant 24:S249-54. 2005
  10. ncbi Utility of peritransplant and rescue intravenous immunoglobulin and extracorporeal immunoadsorption in lung transplant recipients sensitized to HLA antigens
    James Z Appel
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Hum Immunol 66:378-86. 2005

Research Grants

  1. Immune Parameters in a Steroid Sparing Clinical Trial
    Nancy Reinsmoen; Fiscal Year: 2005

Collaborators

Detail Information

Publications20

  1. ncbi Acceptable donor-specific antibody levels allowing for successful deceased and living donor kidney transplantation after desensitization therapy
    Nancy L Reinsmoen
    HLA Laboratory, Cedars Sinai Medical Center, 8723 Alden Drive, SSB 197, Los Angeles, CA 90048, USA
    Transplantation 86:820-5. 2008
    ....
  2. ncbi Pretransplant donor-specific and non-specific immune parameters associated with early acute rejection
    Nancy L Reinsmoen
    David Geffen School of Medicine at UCLA, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Transplantation 85:462-70. 2008
    ..The aim of our studies was to determine whether pretransplant immune parameters were associated with posttransplant early acute rejection, unstable creatinine courses, and poor graft outcome...
  3. ncbi Anti-angiotensin type 1 receptor antibodies associated with antibody mediated rejection in donor HLA antibody negative patients
    Nancy L Reinsmoen
    Cedars Sinai Medical Center, HLA Laboratory, Comprehensive Transplant Center, Los Angeles, CA 90048, USA
    Transplantation 90:1473-7. 2010
    ....
  4. ncbi A new era for T-cell immune function assays in transplantation
    N L Reinsmoen
    Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Tissue Antigens 75:658-67. 2010
    ..This review focuses on the current use of cellular testing in clinical transplantation...
  5. ncbi Calculated PRA: initial results show benefits for sensitized patients and a reduction in positive crossmatches
    J M Cecka
    UCLA Immunogenetics Center, Department of Pathology, University of California Los Angeles, Los Angeles, CA, USA
    Am J Transplant 11:719-24. 2011
    ....
  6. ncbi Rituximab and intravenous immune globulin for desensitization during renal transplantation
    Ashley A Vo
    Comprehensive Transplant Center, Transplant Immunology Laboratory, Cedars Sinai Medical Center, Los Angeles 90048, USA
    N Engl J Med 359:242-51. 2008
    ..This exploratory, open-label, phase 1-2, single-center study examined whether intravenous immune globulin plus rituximab could reduce anti-HLA antibody levels and improve transplantation rates...
  7. ncbi Use of intravenous immune globulin and rituximab for desensitization of highly HLA-sensitized patients awaiting kidney transplantation
    Ashley A Vo
    Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Transplantation 89:1095-102. 2010
    ....
  8. ncbi Acute antibody-mediated rejection of cardiac transplants
    Elaine F Reed
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, 1000 Veteran Avenue, Room 1335, Los Angeles, CA 90095, USA
    J Heart Lung Transplant 25:153-9. 2006
    ....
  9. ncbi Pre-transplant panel reactive antibody in lung transplant recipients is associated with significantly worse post-transplant survival in a multicenter study
    Denis Hadjiliadis
    Department of Medicine, Division of Respirology, Toronto General Hospital, Toronto, Ontario, Canada
    J Heart Lung Transplant 24:S249-54. 2005
    ..This may be due to a direct effect of anti-HLA antibodies on the allograft. The effectiveness of treatments such as plasmapheresis and intravenous immunoglobulin prior to transplantation needs to be evaluated...
  10. ncbi Utility of peritransplant and rescue intravenous immunoglobulin and extracorporeal immunoadsorption in lung transplant recipients sensitized to HLA antigens
    James Z Appel
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Hum Immunol 66:378-86. 2005
    ..We discuss the appropriateness and clinical impact of IVIG and ECI in sensitized lung transplant recipients as well as cellular mechanisms that may contribute...
  11. ncbi Anti-HLA antibody analysis and crossmatching in heart and lung transplantation
    Nancy L Reinsmoen
    Department of Pathology, DUMC, Durham, NC, USA
    Transpl Immunol 13:63-71. 2004
    ..Thus, monitoring the presence and the level of anti-HLA antibodies is prognostic of graft outcome and allows for measurement of therapeutic efficacy...
  12. ncbi Role of flow cytometry to define unacceptable HLA antigens in lung transplant recipients with HLA-specific antibodies
    James Z Appel
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Transplantation 81:1049-57. 2006
    ..Using this virtual crossmatch strategy, crossmatching can be safely omitted prior to lung transplantation, thereby decreasing waiting list time and mortality rates for candidates with HLA-specific antibodies...
  13. ncbi Unusual clinical and immunologic manifestations of transplacentally acquired maternal T cells in severe combined immunodeficiency
    Kricia Palmer
    Division of Pediatric Allergy and Immunology, Duke University Medical Center, Durham, NC 27710, USA
    J Allergy Clin Immunol 120:423-8. 2007
    ..We present evidence that these cells can cause allograft rejection and immune cytopenias...
  14. ncbi Revision of the 1996 working formulation for the standardization of nomenclature in the diagnosis of lung rejection
    Susan Stewart
    Papworth Everard Pathology Department, Papworth Hospital, Cambridge, UK
    J Heart Lung Transplant 26:1229-42. 2007
    ..This consensus revision of the working formulation was approved by the ISHLT board of directors in April 2007...
  15. ncbi Cytokine gene polymorphisms are not associated with bronchiolitis obliterans syndrome or survival after lung transplant
    Laurie D Snyder
    Division of Pulmonary, Allergy and Critical Care, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Heart Lung Transplant 25:1330-5. 2006
    ..Cytokine polymorphisms are inconsistently associated with transplant rejection and other adverse outcomes. To address this controversy, we evaluated cytokine single nucleotide polymorphisms (SNPs) in a lung transplant cohort...
  16. ncbi Donor polymorphisms in Toll-like receptor-4 influence the development of rejection after renal transplantation
    Scott M Palmer
    Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Clin Transplant 20:30-6. 2006
    ..In the present investigation, we sought to evaluate the role of innate immune activation through TLR4, in either donor or recipient, upon the development of renal allograft rejection...
  17. ncbi Revision of the 1990 working formulation for the standardization of nomenclature in the diagnosis of heart rejection
    Susan Stewart
    International Society for Heart and Lung Transplantation, Addison, Texas, USA
    J Heart Lung Transplant 24:1710-20. 2005
    ..Technical considerations in biopsy processing are also addressed. This consensus revision of the Working Formulation was approved by the ISHLT Board of Directors in December 2004...
  18. ncbi Innate immunity influences long-term outcomes after human lung transplant
    Scott M Palmer
    Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Am J Respir Crit Care Med 171:780-5. 2005
    ....
  19. ncbi The role of innate immunity in acute allograft rejection after lung transplantation
    Scott M Palmer
    Department of Medicine, Duke University Medical Center, Durham, NC, USA
    Am J Respir Crit Care Med 168:628-32. 2003
    ..Therapies directed at inhibition of innate immune responses mediated by TLR4 may represent a novel and effective means to prevent acute rejection after lung transplantation...
  20. ncbi Development of an antibody specific to major histocompatibility antigens detectable by flow cytometry after lung transplant is associated with bronchiolitis obliterans syndrome
    Scott M Palmer
    Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Transplantation 74:799-804. 2002
    ..The use of flow cytometry based panel reactive antibody (flow-PRA) provides a highly sensitive means to identify the development of de novo anti-HLA antibodies in lung recipients...

Research Grants4

  1. Immune Parameters in a Steroid Sparing Clinical Trial
    Nancy Reinsmoen; Fiscal Year: 2005
    ..Thus, the overall study is designed to use immune parameters to identify recipients at low vs. high risk for poor graft outcome, thereby allowing for individualization of immunosuppression aimed at improving long-term graft outcome. ..