Research Topics
Genomes and Genes | Tadayuki AkagiSummaryAffiliation: Cedars-Sinai Medical Center Country: USA Publications
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Publications
Impaired response to GM-CSF and G-CSF, and enhanced apoptosis in C/EBPbeta-deficient hematopoietic cellsTadayuki Akagi
Division of Hematology and Oncology, Cedars Sinai Medical Center, University of California Los Angeles School of Medicine, Los Angeles, CA 90048, USA
Blood 111:2999-3004. 2008..Our present results indicate that C/EBPbeta helps regulate survival of neutrophils, downstream of the granulocyte colony stimulating factor receptor...
Molecular allelokaryotyping of T-cell prolymphocytic leukemia cells with high density single nucleotide polymorphism arrays identifies novel common genomic lesions and acquired uniparental disomyDaniel Nowak
Division of Hematology and Oncology, Cedars Sinai Medical Center, UCLA School of Medicine, 8700 Beverly Blvd, Los Angeles, CA 90048, USA
Haematologica 94:518-27. 2009....
Vitamin D compounds and myelodysplastic syndromeRyoko Okamoto
Division of Hematology and Oncology, Cedar-Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA 90048, USA
Leuk Lymphoma 49:12-3. 2008
In vivo deficiency of both C/EBP? and C/EBP? results in highly defective myeloid differentiation and lack of cytokine responseTadayuki Akagi
Division of Hematology and Oncology, Cedars Sinai Medical Center, University of California Los Angeles School of Medicine, Los Angeles, California, United States of America
PLoS ONE 5:e15419. 2010....
Frequent genomic abnormalities in acute myeloid leukemia/myelodysplastic syndrome with normal karyotypeTadayuki Akagi
Division of Hematology and Oncology, Cedars Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA 90048, USA
Haematologica 94:213-23. 2009..Here, we identified hidden genomic alterations and novel disease-related regions in normal karyotype acute myeloid leukemia/myelodysplastic syndrome samples...
Genomic profiling of adult acute lymphoblastic leukemia by single nucleotide polymorphism oligonucleotide microarray and comparison to pediatric acute lymphoblastic leukemiaRyoko Okamoto
Division of Hematology and Oncology, Cedars Sinai Medical Center, UCLA School of Medicine, 8700, Beverly Blvd, Los Angeles, CA90048, USA
Haematologica 95:1481-8. 2010..The inferior prognosis in adult acute lymphoblastic leukemia is not fully understood but could be attributed, in part, to differences in genomic alterations found in adult as compared to in pediatric acute lymphoblastic leukemia...
Chromosomal abnormalities and novel disease-related regions in progression from Barrett's esophagus to esophageal adenocarcinomaTadayuki Akagi
Division of Hematology and Oncology, Cedars Sinai Medical Center, UCLA School of Medicine, Los Angeles, CA, USA
Int J Cancer 125:2349-59. 2009..Thus, this SNP-chip analysis has identified several early cytogenetic events and novel candidate cancer-related genes that are potentially involved in the evolution of BE to EAC...
Hidden abnormalities and novel classification of t(15;17) acute promyelocytic leukemia (APL) based on genomic alterationsTadayuki Akagi
Division of Hematology and Oncology, Cedars Sinai Medical Center, University of California at Los Angeles School of Medicine, Los Angeles, CA, USA
Blood 113:1741-8. 2009..Here, we showed for the first time hidden abnormalities and novel disease-related genomic changes in t(15;17) APL...
GABPalpha regulates Oct-3/4 expression in mouse embryonic stem cellsKeita Kinoshita
Department of Stem Cell Biology, Graduate School of Medical Science, Kanazawa University, 13 1 Takara machi, Kanazawa, Ishikawa 920 8640, Japan
Biochem Biophys Res Commun 353:686-91. 2007..Moreover, the induction of Oct-3/4 repressors Cdx-2, Coup-tf1, and GCNF was stimulated by GABPalpha knockdown. These data suggest that GABPalpha upregulates the expression of Oct-3/4 via downregulation of Oct-3/4 repressors...
Identification of Zfp-57 as a downstream molecule of STAT3 and Oct-3/4 in embryonic stem cellsTadayuki Akagi
Department of Stem Cell Biology, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640, Japan
Biochem Biophys Res Commun 331:23-30. 2005..These data suggest that Zfp-57 is a downstream molecule of STAT3 and Oct-3/4 in ES cells, although dispensable for their self-renewal...
