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| R L FindlingSummaryAffiliation: Case Western Reserve University Country: USA Publications
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Publications
Somatic treatment for depressive illnesses in children and adolescentsRobert L Findling
Department of Psychiatry, University Hospitals of Cleveland, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106 5080, USA
Psychiatr Clin North Am 27:113-37, x. 2004..This article reviews what is known and what needs to be learned about the somatic treatment of pediatric depression...- Long-term, open-label study of risperidone in children with severe disruptive behaviors and below-average IQRobert L Findling
Department of Psychiatry, Case Western Reserve University, University Hospital of Cleveland, OH 44106, USA
Am J Psychiatry 161:677-84. 2004..This study determined the long-term safety and effectiveness of risperidone in treating severe disruptive behavior in children with subaverage intelligence... - A pilot evaluation of the safety, tolerability, pharmacokinetics, and effectiveness of memantine in pediatric patients with attention-deficit/hyperactivity disorder combined typeRobert L Findling
Department of Psychiatry, Case Western Reserve University and Division of Child and Adolescent Psychiatry, University Hospitals of Cleveland, Cleveland, Ohio 44106 5080, USA
J Child Adolesc Psychopharmacol 17:19-33. 2007..Disturbances in N-methyl-D-aspartate (NMDA) receptor activity may play a role in attention-deficit/hyperactivity disorder (ADHD)... - Atypical antipsychotics in the treatment of children and adolescentsRobert L Findling
Department of Psychiatry, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio 44106-5080, USA
J Clin Psychiatry 65:3-4. 2004 - Atypical antipsychotics in the treatment of children and adolescents: clinical applicationsRobert L Findling
Department of Psychiatry, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio 44106 5080, USA
J Clin Psychiatry 65:30-44. 2004..Evidence on the use of atypical antipsychotics in children and adolescents is summarized in this review... - A 26-week open-label study of quetiapine in children with conduct disorderRobert L Findling
Department of Psychiatry, University Hospitals of Cleveland Case Western Reserve University, Cleveland, Ohio 44106 5080, USA
J Child Adolesc Psychopharmacol 17:1-9. 2007..The aim of this study was to describe the long-term safety and effectiveness of quetiapine in conduct disorder (CD)... - Quetiapine in nine youths with autistic disorderRobert L Findling
Departments of Psychiatry and Pediatrics, University Hospitals of Cleveland Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106 5080, USA
J Child Adolesc Psychopharmacol 14:287-94. 2004..The aim of this study was to examine the effectiveness of quetiapine in adolescents suffering from autistic disorder (AD)... - The relevance of pharmacokinetic studies in designing efficacy trials in juvenile major depressionRobert L Findling
Departments of Psychiatry and Pediatrics, University Hospitals of Cleveland Case Western Reserve University, Cleveland, Ohio 44106, USA
J Child Adolesc Psychopharmacol 16:131-45. 2006..Utilizing scientifically supported dosing strategies provides the best chance for any given drug to demonstrate both efficacy and acceptable tolerability in definitive, placebo-controlled studies... - Combination lithium and divalproex sodium in pediatric bipolar symptom re-stabilizationRobert L Findling
Department of Psychiatry, Case Western Reserve University, University Hospitals, Cleveland, OH 44106, USA
J Am Acad Child Adolesc Psychiatry 45:142-8. 2006..The primary goal of this study was to assess the rate of re-stabilization after the resumption of lithium (Li) plus divalproex (DVPX) following relapse on either agent as monotherapy... - Update on the treatment of bipolar disorder in children and adolescentsRobert L Findling
Department of Psychiatry, Case Western Reserve University School of Medicine, University Hospitals of Cleveland, 11100 Euclid Avenue, Cleveland, OH 44106 5080, USA
Eur Psychiatry 20:87-91. 2005.... - Double-blind 18-month trial of lithium versus divalproex maintenance treatment in pediatric bipolar disorderRobert L Findling
Department of Psychiatry, Case Western Reserve University, USA
J Am Acad Child Adolesc Psychiatry 44:409-17. 2005.... - Early symptoms of mania and the role of parental riskRobert L Findling
Department of Psychiatry, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH 44106, USA
Bipolar Disord 7:623-34. 2005.... - Pharmacologic treatment of behavioral symptoms in autism and pervasive developmental disordersRobert L Findling
Division of Child and Adolescent Psychiatry, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio, USA
J Clin Psychiatry 66:26-31. 2005..This article discusses the efficacy and tolerability of various medications and alternative interventions in addressing the symptoms of autism and other PDDs... - Effectiveness, safety, and pharmacokinetics of quetiapine in aggressive children with conduct disorderRobert L Findling
Department of Psychiatry, Case Western Reserve University University Hospitals of Cleveland, Cleveland, OH 44106 5080, USA
J Am Acad Child Adolesc Psychiatry 45:792-800. 2006..To provide an initial description of the effectiveness and pharmacokinetics (PK) of quetiapine in aggressive children with conduct disorder (CD)... - Use of antipsychotics in children and adolescentsRobert L Findling
Department of Psychiatry, University Hospitals of Cleveland, Cleveland, Ohio 44106 5080, USA
J Clin Psychiatry 66:29-40. 2005.... - Short- and long-term cardiovascular effects of mixed amphetamine salts extended release in childrenRobert L Findling
University Hospitals of Cleveland, Cleveland, Ohio 44106 5080, USA
J Pediatr 147:348-54. 2005.... - Double-blind, placebo-controlled trial of divalproex monotherapy in the treatment of symptomatic youth at high risk for developing bipolar disorderRobert L Findling
Department of Psychiatry, Case Western Reserve University, and the University Hospitals of Cleveland, Cleveland, Ohio 44106 5080, USA
J Clin Psychiatry 68:781-8. 2007..To determine if divalproex sodium was superior to placebo in the treatment of symptomatic youths who suffer from a bipolar spectrum disorder and who also have a parent with a diagnosis of a bipolar illness... - Multiple dose pharmacokinetics of paroxetine in children and adolescents with major depressive disorder or obsessive-compulsive disorderRobert L Findling
Department of Psychiatry, Case Western Reserve University, University Hospitals of Cleveland, OH 44106 5080, USA
Neuropsychopharmacology 31:1274-85. 2006..Certain gastrointestinal and behavioral activation events (aggressive reaction and nervousness) were reported more frequently in the youngest age group... - Prolactin levels during long-term risperidone treatment in children and adolescentsRobert L Findling
University Hospitals of Cleveland Case Western Reserve University, Cleveland, Ohio 44106, USA
J Clin Psychiatry 64:1362-9. 2003..This analysis was designed to investigate prolactin levels in children and adolescents on long-term risperidone treatment and explore any relationship with side effects hypothetically attributable to prolactin (SHAP)... - An open-label pilot study of St. John's wort in juvenile depressionRobert L Findling
Department of Psychiatry, Case Western Reserve University University Hospitals of Cleveland, USA
J Am Acad Child Adolesc Psychiatry 42:908-14. 2003..This pilot study examined the effectiveness, safety, tolerability, and pharmacodynamics of Hypericum perforatum (St. John's wort) in the treatment of youths diagnosed with major depressive disorder... - Combination lithium and divalproex sodium in pediatric bipolarityRobert L Findling
Department of Psychiatry, Case Western Reserve University School of Medicine, USA
J Am Acad Child Adolesc Psychiatry 42:895-901. 2003..Many youths with bipolar disorder do not respond to DVPX or Li monotherapy. An open-label study was conducted to examine the effectiveness of combination DVPX and Li therapy with youths diagnosed with bipolar disorder... - Clinical decision-making using the General Behavior Inventory in juvenile bipolarityRobert L Findling
Department of Psychiatry, University Hospitals of Cleveland Case Western Reserve University School of Medicine, Cleveland, OH 44106 5080, USA
Bipolar Disord 4:34-42. 2002..The General Behavior Inventory (GBI) is a questionnaire that has utility in the assessment of mood disorders in adults. The purpose of this study was to examine how the GBI might optimally be used in the assessment of youths... - Use of quetiapine in children and adolescentsRobert L Findling
Division of Child and Adolescent Psychiatry, University Hospitals of Cleveland Case Western Reserve University, Cleveland, Ohio 44106 5080, USA
J Clin Psychiatry 63:27-31. 2002..Methodologically rigorous studies with substantive numbers of subjects are needed to confirm or refute these preliminary impressions... - A prospective, open-label trial of olanzapine in adolescents with schizophreniaRobert L Findling
Department of Psychiatry, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, OH 44106, USA
J Am Acad Child Adolesc Psychiatry 42:170-5. 2003..Olanzapine is an atypical antipsychotic that has efficacy in adults with psychotic disorders. This preliminary study examined the effectiveness of olanzapine in adolescents with schizophrenia or its related conditions... - Rapid, continuous cycling and psychiatric co-morbidity in pediatric bipolar I disorderR L Findling
Department of Psychiatry, University Hospitals of Cleveland Case Western Reserve University School of Medicine, Case Western Reserve University, Cleveland, OH 44106 5080, USA
Bipolar Disord 3:202-10. 2001..The primary purpose of this study was to describe the clinical presentation of bipolar I disorder (BP-I) as it occurs in children and adolescents and to assess whether the manifestations of BP-I were similar in both age groups... - Somatic treatment for depressive illnesses in children and adolescentsRobert L Findling
Department of Psychiatry, University Hospitals of Cleveland, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106 5080, USA
Child Adolesc Psychiatr Clin N Am 11:555-78, ix. 2002..This article reviews what is known and what needs to be learned about the somatic treatment of pediatric depression... - Treatment-emergent mania/hypomania during antidepressant monotherapy in patients with rapid cycling bipolar disorderKeming Gao
Department of Psychiatry, Bipolar Disorder Research Center at Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, 10524 Euclid Avenue, Cleveland, OH 44106, USA
Bipolar Disord 10:907-15. 2008..To study treatment-emergent mania/hypomania (TEM) associated with second-generation antidepressant monotherapy in patients with rapid cycling bipolar disorder (RCBD)... - A 6-month, double-blind, maintenance trial of lithium monotherapy versus the combination of lithium and divalproex for rapid-cycling bipolar disorder and Co-occurring substance abuse or dependenceDavid E Kemp
Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, Ohio, USA
J Clin Psychiatry 70:113-21. 2009.... - Discriminative validity of parent report of hypomanic and depressive symptoms on the General Behavior InventoryE A Youngstrom
Department of Psychology, Case Western Reserve University, 11220 Bellflower Road, Cleveland, Ohio 44106, USA
Psychol Assess 13:267-76. 2001..80. Results indicate that clinicians can use the parent-completed GBI to derive clinically meaningful information about mood disorders in youths... - New data on the use of lithium, divalproate, and lamotrigine in rapid cycling bipolar disorderJ R Calabrese
Case Western Reserve University School of Medicine, University Hospitals of Cleveland, 11400 Euclid Avenue, Suite 200, Cleveland, OH 44106, USA
Eur Psychiatry 20:92-5. 2005..In addition, lamotrigine has the potential to complement the spectrum of lithium and divalproate through its greater efficacy for depressive symptoms... - Correlates of historical suicide attempt in rapid-cycling bipolar disorder: a cross-sectional assessmentKeming Gao
Department of Psychiatry, Case Western University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio, USA
J Clin Psychiatry 70:1032-40. 2009..A rapid-cycling course in bipolar disorder has previously been identified as a risk factor for attempted suicide. This study investigated factors associated with suicide attempts in patients with rapid-cycling bipolar I or II disorder... - Medical and substance use comorbidity in bipolar disorderDavid E Kemp
Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH, USA
J Affect Disord 116:64-9. 2009.... - A multiple-center, randomized, double-blind, placebo-controlled study of oral aripiprazole for treatment of adolescents with schizophreniaRobert L Findling
Department of Child and Adolescent Psychiatry, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106 5080, USA
Am J Psychiatry 165:1432-41. 2008..This study was designed to examine the acute efficacy, safety, and tolerability of aripiprazole for adolescents with schizophrenia... - A pilot pharmacotherapy trial for depressed youths at high genetic risk for bipolarityRobert L Findling
Department of Psychiatry, University Hospitals Case Medical Center Case Western Reserve University, Cleveland, Ohio 44106, USA
J Child Adolesc Psychopharmacol 18:615-21. 2008..As a result, future treatment studies in this population appear to be warranted, not only due to the putative impending risk of developing bipolar disorder, but also the manifest risk of current depressive episodes... - Pharmacological treatment of pathologic aggression in childrenDrew H Barzman
Division of Child and Adolescent Psychiatry, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
Int Rev Psychiatry 20:151-7. 2008..Future research is needed to evaluate whether the long-term risks associated with the pharmacological treatment of PA outweigh the potential benefits to the child... - Acute treatment of pediatric bipolar I disorder, manic or mixed episode, with aripiprazole: a randomized, double-blind, placebo-controlled studyRobert L Findling
Department of Psychiatry, Division of Child and Adolescent Psychiatry, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH 44106, USA
J Clin Psychiatry 70:1441-51. 2009..To determine the efficacy and safety of aripiprazole for the treatment of pediatric bipolar I disorder, manic or mixed episode, with or without psychotic features... - Differential interactions between comorbid anxiety disorders and substance use disorder in rapid cycling bipolar I or II disorderKeming Gao
Department of Psychiatry, Bipolar Disorder Research Center at Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio, USA
J Affect Disord 110:167-73. 2008..Anxiety disorders (AD) and substance use disorders (SUD) commonly co-occur with bipolar disorder. This study was undertaken to assess AD-SUD-bipolar subtype interactions... - Current research in child and adolescent bipolar disorderChristine A Demeter
Department of Psychiatry, University Hospitals Case Medical Center Case Western Reserve University, Cleveland, Ohio 44106 5080, USA
Dialogues Clin Neurosci 10:215-28. 2008..This paper will review what is currently known and what still is left to learn about clinically salient topics that pertain to bipolar disorder in children and adolescents... - Family conflict moderates response to pharmacological intervention in pediatric bipolar disorderLisa D Townsend
Case Western Reserve University, Cleveland, 11400 Euclid Avenue, OH 44106, USA
J Child Adolesc Psychopharmacol 17:843-52. 2007..Family conflict affects the expression of psychopathology in youth. This study investigated whether family conflict moderates response to medication in youth with bipolar disorder... - Adherence to pharmacological treatment for juvenile bipolar disorderDennis Drotar
Department of Psychiatry, Case Western Reserve University, USA
J Am Acad Child Adolesc Psychiatry 46:831-9. 2007..The objective of this study was to describe the prevalence and correlates of adherence to divalproex sodium (DVPX) and lithium carbonate (Li) combination treatment during the initial stabilization treatment phase... - Evaluation and comparison of psychometric instruments for pediatric bipolar spectrum disorders in four age groupsThomas W Frazier
Department of Psychiatry, University Hospitals Case Medical Center, Cleveland, OH, USA
J Child Adolesc Psychopharmacol 17:853-66. 2007..The CDRS-R may be better conceptualized as a two-factor measure in older adolescents. The semistructured K-SADS interview can be used to generate reliable diagnoses across a broad age range... - Atypical antipsychotic treatment of disruptive behavior disorders in children and adolescentsRobert L Findling
Department of Psychiatry, University Hospitals Case Medical Center, Cleveland, Ohio 44106 5080, USA
J Clin Psychiatry 69:9-14. 2008.... - Short-term cardiovascular effects of methylphenidate and adderallR L Findling
Department of Psychiatry and Pediatrics, University Hospitals of Cleveland, Case Western Reserve University, OH 44106-5080, USA
J Am Acad Child Adolesc Psychiatry 40:525-9. 2001..In addition, under similar conditions, using similar methods, both medication treatments led to changes in blood pressure and pulse that were clinically insignificant... - Employing parent, teacher, and youth self-report checklists in identifying pediatric bipolar spectrum disorders: an examination of diagnostic accuracy and clinical utilityShoshana Y Kahana
Case Western Reserve University, Cleveland, Ohio 44106, USA
J Child Adolesc Psychopharmacol 13:471-88. 2003..Results indicate that the Child Behavior Checklist has limited utility when attempting to derive clinically meaningful information about the presentation of juvenile BPSD... - Who are the comorbid adolescents? Agreement between psychiatric diagnosis, youth, parent, and teacher reportEric A Youngstrom
Department of Psychology, Case Western Reserve University, Cleveland, Ohio 44106 7123, USA
J Abnorm Child Psychol 31:231-45. 2003..14-.40). Results also indicate that single DSM-IV disorders, such as bipolar disorder, can manifest "comorbid" patterns of behavior problems on checklists... - Clinical correlates of patients with rapid-cycling bipolar disorder and a recent history of substance use disorder: a subtype comparison from baseline data of 2 randomized, placebo-controlled trialsKeming Gao
Department of Psychiatry, Bipolar Disorder Research Center at the Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
J Clin Psychiatry 69:1057-63. 2008..To compare clinical variables in patients with rapid-cycling bipolar I or II disorder and a recent history of substance use disorder (SUD)... - Efficacy and tolerability of second-generation antipsychotics in children and adolescents with schizophreniaSanjiv Kumra
Division of Child and Adolescent Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454, USA
Schizophr Bull 34:60-71. 2008..Such a substantial risk points to the urgent need to develop therapeutic strategies to prevent and/or mitigate weight gain and diabetes early in the course of treatment in this population... - Guns, adolescents, and mental illnessNora K McNamara
Department of Psychiatry, University Hospitals Case Medical Center/Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106-5080, USA
Am J Psychiatry 165:190-4. 2008 - Aripiprazole in children with attention-deficit/hyperactivity disorderRobert L Findling
Department of Psychiatry, University Hospitals Case Medical Center Case Western Reserve University, Cleveland, Ohio 44106 5080, USA
J Child Adolesc Psychopharmacol 18:347-54. 2008..To examine the effectiveness and cognitive effects of aripiprazole (APZ) in children with a primary diagnosis of attention-deficit/hyperactivity disorder (ADHD)... - Psychopharmacology of pediatric bipolar disorder: a reviewSylvester Smarty
Child and Adolescent Psychiatry, University Hospitals of Cleveland Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106, USA
Psychopharmacology (Berl) 191:39-54. 2007..For these reasons, there is a need for effective treatment for PBD... - Double-blind randomized trial of risperidone versus divalproex in pediatric bipolar disorderMani N Pavuluri
Department of Psychiatry, Institute for Juvenile Research, University of Illinois at Chicago, USA
Bipolar Disord 12:593-605. 2010..To determine the relative effects of risperidone and divalproex in pediatric mania... - Developmental and subtype differences in behavioral assets and problems in children diagnosed with ADHDElizabeth J Short
Case Western Reserve University, Cleveland, OH 44106, USA
J Atten Disord 11:28-36. 2007..Developmental and subtype differences in behavioral assets and problems were examined in 318 children newly diagnosed with ADHD... - Age at onset and gender of schizophrenic patients in relation to neuroleptic resistanceH Y Meltzer
Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, USA
Am J Psychiatry 154:475-82. 1997..The authors compared age at onset in neuroleptic-resistant and -responsive schizophrenic patients to determine whether the gender difference in age at onset is related to response to neuroleptic treatment... - Paediatric uses of atypical antipsychoticsR L Findling
Departments of Psychiatry and Paediatrics, University Hospitals of Cleveland Case Western Reserve University, Cleveland, Ohio, USA
Expert Opin Pharmacother 1:935-45. 2000..Based upon what is known about these agents, a rational approach to the use of these drugs in juveniles is offered... - Long-term effectiveness and safety of lisdexamfetamine dimesylate in school-aged children with attention-deficit/hyperactivity disorderRobert L Findling
Child and Adolescent Psychiatry, University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
CNS Spectr 13:614-20. 2008..In short-term studies, once-daily LDX provided efficacy throughout the day. This study presented here was conducted to assess the long-term safety, tolerability, and effectiveness of LDX in 6- to 12-year-olds with ADHD... - A linguistic analysis of in-office dialogue among psychiatrists, parents, and child and adolescent patients with ADHDRobert L Findling
Case Western Reserve University, USA
J Atten Disord 13:78-86. 2009..The aim was to evaluate in-office discussions of ADHD and psychiatric comorbidities... - First-dose pharmacokinetics of lithium carbonate in children and adolescentsRobert L Findling
University Hospitals, Case Medical Center, Case Western Reserve University, Cleveland, OH 44106, USA
J Clin Psychopharmacol 30:404-10. 2010..The developed population pharmacokinetic model may be used to predict other dosage regimens, support scaling from adult to pediatric pharmacokinetics, and support the design of future clinical trials... - Medical comorbidity in bipolar disorder: relationship between illnesses of the endocrine/metabolic system and treatment outcomeDavid E Kemp
Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH 44106, USA
Bipolar Disord 12:404-13. 2010..It was hypothesized that illnesses of the endocrine/metabolic system would be associated with greater psychiatric symptom burden and would impact the response to treatment with lithium and valproate... - Effects of guanfacine extended release on oppositional symptoms in children aged 6-12 years with attention-deficit hyperactivity disorder and oppositional symptoms: a randomized, double-blind, placebo-controlled trialDaniel F Connor
Department of Psychiatry, University of Connecticut School of Medicine, Farmington, Connecticut 06030 1410, USA
CNS Drugs 24:755-68. 2010..Wayne, PA, USA) in the treatment of oppositional symptoms in children aged 6-12 years with a diagnosis of attention-deficit hyperactivity disorder (ADHD) and the presence of oppositional symptoms... - A randomized, double-blind, placebo-controlled, parallel-group study of methylphenidate transdermal system in pediatric patients with attention-deficit/hyperactivity disorderRobert L Findling
University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
J Clin Psychiatry 69:149-59. 2008..To evaluate the efficacy and safety of methylphenidate transdermal system compared with placebo, using osmotic-release oral system (OROS) methylphenidate as a reference therapy... - Initiation of stimulant and antidepressant medication and clinical presentation in juvenile bipolar I disorderMaria E Pagano
Department of Psychiatry, University Hospitals of Cleveland, Case Western Reserve University School of Medicine, Cleveland, OH 44106 5080, USA
Bipolar Disord 10:334-41. 2008..Another aim was to investigate differences in clinical presentation between youths prescribed stimulant or antidepressant medication before and after the onset of juvenile BP I disorder... - Effectiveness, safety, and tolerability of lisdexamfetamine dimesylate in children with attention-deficit/hyperactivity disorder: an open-label, dose-optimization studyRobert L Findling
University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
J Child Adolesc Psychopharmacol 19:649-62. 2009..The aim of this study was to assess the effectiveness and safety of lisdexamfetamine dimesylate (LDX) in children with attention-deficit/hyperactivity disorder (ADHD)... - A US perspective of the CANMAT bipolar guidelinesJoseph R Calabrese
Case Western Reserve University, Cleveland, OH 44106, USA
Bipolar Disord 7:70-2. 2005 - Venlafaxine in the treatment of children and adolescents with attention-deficit/hyperactivity disorderRobert L Findling
Department of Psychiatry, University Hospitals Case Medical Center, Cleveland, Ohio 44106 5080, USA
J Child Adolesc Psychopharmacol 17:433-45. 2007..The objectives of this pilot study were to explore the changes in symptom severity, tolerability, and the pharmacodynamics of venlafaxine treatment in youths with attention-deficit/hyperactivity disorder (ADHD)... - Pharmacologic treatment of adolescent and child schizophreniaChristopher M Young
Division of Child and Adolescent Psychiatry, University Hospitals of Cleveland, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
Expert Rev Neurother 4:53-60. 2004..Acute management as well as continuation and maintenance therapy recommendations are made... - Gender differences in criminality: bipolar disorder with co-occurring substance abuseSusan Hatters Friedman
Department of Psychiatry, University Hospitals of Cleveland, Hanna Pavilion, 11100 Euclid Avenue, Cleveland, OH 44106, USA
J Am Acad Psychiatry Law 33:188-95. 2005..Implications from this pilot study include the need for earlier identification of bipolar disorder and for the increased availability of psychiatric and substance abuse services within correctional facilities... - A 20-month, double-blind, maintenance trial of lithium versus divalproex in rapid-cycling bipolar disorderJoseph R Calabrese
Case Western Reserve University, University Hospitals of Cleveland, Cleveland, OH 44106, USA
Am J Psychiatry 162:2152-61. 2005..The authors tested the hypothesis that divalproex would be more effective than lithium in the long-term management of patients with recently stabilized rapid-cycling bipolar disorder... - Mood state at study entry as predictor of the polarity of relapse in bipolar disorderJoseph R Calabrese
Case University School of Medicine, University Hospitals of Cleveland, 11400 Euclid Avenue, Suite 200, Cleveland, OH 44106, USA
Biol Psychiatry 56:957-63. 2004..We conclude that putative mood stabilizers must be tested in recently manic and recently depressed patients to determine their spectrum of prophylactic efficacy... - Comorbid anxiety and substance use disorders associated with a lower use of mood stabilisers in patients with rapid cycling bipolar disorder: a descriptive analysis of the cross-sectional data of 566 patientsK Gao
Department of Psychiatry, Mood and Anxiety Clinic at Mood Disorders Program, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, OH, USA
Int J Clin Pract 64:336-44. 2010..To study mood stabiliser treatment in patients with bipolar disorder with or without anxiety disorders (ADs) and/or substance use disorders (SUDs)... - Prevention of recurrent postpartum depression: a randomized clinical trialK L Wisner
Department of Reproductive Biology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
J Clin Psychiatry 62:82-6. 2001..We conducted a double-blind, randomized clinical trial to test the efficacy of nortriptyline in the prevention of recurrent PPMD... - A double-blind, placebo-controlled study of modified-release methylphenidate in children with attention-deficit/hyperactivity disorderLaurence L Greenhill
New York State Psychiatric Institute, New York, New York 10032, USA
Pediatrics 109:E39. 2002..To compare the efficacy, safety, and tolerability of once-daily administration of modified-release methylphenidate (MPH MR) with placebo in children with attention-deficit/hyperactivity disorder (ADHD)... - A double-blind, randomized, placebo-controlled trial of oxcarbazepine in the treatment of bipolar disorder in children and adolescentsKaren Dineen Wagner
Department of Psychiatry and Behavioral Sciences, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77755 0188, USA
Am J Psychiatry 163:1179-86. 2006..This multicenter trial examined the efficacy and safety of oxcarbazepine in the treatment of bipolar disorder in children and adolescents... - Elevated thyrotropin in bipolar youths prescribed both lithium and divalproex sodiumBarbara L Gracious
Strong Memorial Hospital, University of Rochester Medical Center, Rochester, NY 14642, USA
J Am Acad Child Adolesc Psychiatry 43:215-20. 2004..To examine the effect of combined lithium and divalproex sodium on thyroid-stimulating hormone (TSH) levels in children and adolescents with bipolar disorders and to identify risk factors for lithium-induced hypothyroidism... - Risperidone in children with disruptive behavior disorders and subaverage intelligence: a 1-year, open-label study of 504 patientsJan Croonenberghs
University Center of Child and Adolescent Psychiatry, University of Antwerp, Belgium
J Am Acad Child Adolesc Psychiatry 44:64-72. 2005..To determine the long-term safety and effectiveness of risperidone for severe disruptive behaviors in children... - Juvenile maladaptive aggression: a review of prevention, treatment, and service configuration and a proposed research agendaDaniel F Connor
Department of Psychiatry MC1410, University of Connecticut Health Center, Farmington 06030 1410, USA
J Clin Psychiatry 67:808-20. 2006..To propose a research agenda for disorders of aggression in child and adolescent psychiatry... - Efficacy of Adderall and methylphenidate in attention deficit hyperactivity disorder: a drug-placebo and drug-drug response curve analysis of a naturalistic studyStephen V Faraone
Pediatric Psychopharmacology Unit of the Child Psychiatry Service, Massachusetts General Hospital, Boston, MA 02114, USA
Int J Neuropsychopharmacol 5:121-9. 2002..The analyses also highlight an important subgroup of placebo responders, which suggests that future research should focus on how to predict robust placebo response in ADHD patients... - Validation of the Mood Disorder Questionnaire for bipolar disorders in adolescentsKaren Dineen Wagner
Department of Psychiatry and Behavioral Sciences, University of Texas Medical Branch, Galveston 77555 0188, USA
J Clin Psychiatry 67:827-30. 2006.... - Pediatric bipolar disorder: validity, phenomenology, and recommendations for diagnosisEric A Youngstrom
Department of Psychology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 3270, USA
Bipolar Disord 10:194-214. 2008..To find, review, and critically evaluate evidence pertaining to the phenomenology of pediatric bipolar disorder and its validity as a diagnosis... - Treatment of early-onset schizophrenia spectrum disorders (TEOSS): rationale, design, and methodsJon McClellan
University of Washington, Seattle, USA
J Am Acad Child Adolesc Psychiatry 46:969-78. 2007..The rationale, design, and methods of the Treatment of Early Onset Schizophrenia Spectrum Disorders Study are described... - Observed clinical and health services outcomes in pediatric inpatients treated with atypical antipsychotics: 1999-2003Scott C Flanders
Ortho McNeil Janssen Scientific Affairs, L L C, Titusville, New Jersey, USA
J Child Adolesc Psychopharmacol 17:312-27. 2007..The aim of this study was to compare clinical and health services outcomes in pediatric inpatients prescribed an atypical antipsychotic (AA) to those not prescribed an AA at discharge... - Treatment of early-onset schizophrenia spectrum disorders (TEOSS): demographic and clinical characteristicsJean A Frazier
Cambridge Health Alliance, Harvard Medical School, Cambridge, MA, USA
J Am Acad Child Adolesc Psychiatry 46:979-88. 2007..We examined baseline demographic and clinical profiles of youths enrolled from 2001 to 2006 in the publicly funded multicenter, randomized controlled trial Treatment of Early-Onset Schizophrenia Spectrum Disorders... - Efficacy and tolerability of lisdexamfetamine dimesylate (NRP-104) in children with attention-deficit/hyperactivity disorder: a phase III, multicenter, randomized, double-blind, forced-dose, parallel-group studyJoseph Biederman
Department of Pediatric Psychopharmacology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Clin Ther 29:450-63. 2007..Following ingestion, the pharmacologically active d-amphetamine molecule is gradually released by rate-limited hydrolysis... - Prepubertal bipolar I disorder and bipolar disorder NOS are separable from ADHDRobert M Post
J Clin Psychiatry 65:898-902. 2004 - A randomized, placebo-controlled trial of citalopram for the treatment of major depression in children and adolescentsKaren Dineen Wagner
Department of Psychiatry and Behavioral Sciences, University of Texas Medical Branch, Galveston, TX 77755, USA
Am J Psychiatry 161:1079-83. 2004..The current study investigated the efficacy and safety of citalopram compared with placebo in the treatment of pediatric patients with major depression... - Double-blind, placebo-controlled study of risperidone for the treatment of disruptive behaviors in children with subaverage intelligenceMichael G Aman
Nisonger Center UAP, Ohio State University, Columbus 43210 1257, USA
Am J Psychiatry 159:1337-46. 2002..The short-term efficacy and safety of risperidone in the treatment of disruptive behaviors was examined in a well-characterized cohort of children with subaverage intelligence... - Comparing the effects of sampling designs on the diagnostic accuracy of eight promising screening algorithms for pediatric bipolar disorderEric Youngstrom
Department of Psychology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 3270, USA
Biol Psychiatry 60:1013-9. 2006..The present investigation compared eight screening algorithms in the same sample but under two different design strategies... - Double-blind comparison of first- and second-generation antipsychotics in early-onset schizophrenia and schizo-affective disorder: findings from the treatment of early-onset schizophrenia spectrum disorders (TEOSS) studyLinmarie Sikich
University of North Carolina at Chapel Hill, NC 27514, USA
Am J Psychiatry 165:1420-31. 2008....
Research Grants
- TREATMENT OF EARLY ONSET SCHIZOPHRENIA SPECTRUM (TEOSS)Robert Findling; Fiscal Year: 2005..This study will provide information about the comparative effectiveness of the most commonly used and representative antipsychotic drugs in youth with schizophrenia spectrum disorders. ..