Research Topics
| David A IannittiSummaryAffiliation: Carolinas Medical Center Country: USA Publications
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Detail Information
Publications
Technique and outcomes of abdominal incisional hernia repair using a synthetic composite mesh: a report of 455 casesDavid A Iannitti
Division of Gastrointestinal and Minimally Invasive Surgery, Carolinas Medical Center, Charlotte, NC 28203, USA
J Am Coll Surg 206:83-8. 2008..Several different surgical techniques and types of mesh prosthetics are available for repair. We evaluated outcomes of an open ventral hernia repair using a synthetic composite mesh...
International multicentre prospective study on microwave ablation of liver tumours: preliminary resultsDavid M Lloyd
Department of Hepatobiliary and Pancreatic Surgery, Leicester Royal Infirmary, Leicester, UK
HPB (Oxford) 13:579-85. 2011..Microwave ablation (MWA) is increasingly utilized in the treatment of hepatic tumours. Promising single-centre reports have demonstrated its safety and efficacy, but this modality has not been studied in a prospective, multicentre study...
Strength of tissue attachment to composite and ePTFE grafts after ventral hernia repairDavid A Iannitti
Department of Surgery, Carolinas Medical Center, Charlotte, NC 28232, USA
JSLS 11:415-21. 2007..We sought to measure the strength of tissue attachment to mesh after laparoscopic ventral hernia repair in a porcine model...
An evaluation of electrosurgical vessel-sealing devices in biliary tract surgery in a porcine modelWilliam W Hope
Division of Gastrointestinal and Minimally Invasive Surgery, Carolinas Medical Center, Charlotte, NC, USA
HPB (Oxford) 12:703-8. 2010..The purpose of this study was to evaluate two electrosurgical vessel-sealing devices in biliary surgery...
Evaluation of composite mesh for ventral hernia repairJim F Byrd
Section of Hepatopancreaticobiliary Surgery, Department of General Surgery, Carolinas Medical Center, 1000 Blythe Blvd, Charlotte, North Carolina 28203, USA
JSLS 15:298-304. 2011..Composite mesh prostheses incorporate the properties of multiple materials for ventral hernia repair. This study evaluated a polypropylene/ePTFE composite mesh with a novel internal polydioxanone (PDO) absorbable ring...
Colour doppler ultrasonography provides real-time microwave field visualisation in an ex vivo porcine modelJim F Byrd
Section of HepatoPancreatoBiliary Surgery, Department of General Surgery, Carolinas Medical Center, Charlotte, NC 28204, USA
HPB (Oxford) 13:400-3. 2011..The aim of the present study was to determine whether colour Doppler US images observed during microwave ablation correlate with the actual thermocoagulation zone (TCZ) observed in liver tissue...
Guidelines for power and time variables for microwave ablation in an in vivo porcine kidneyWilliam W Hope
Division of Gastrointestinal and Minimally Invasive Surgery, Carolinas Medical Center, Charlotte, North Carolina 28203, USA
J Surg Res 153:263-7. 2009..Microwave technology provides an emerging thermal ablation technique for solid organ tumors. We propose guidelines and recommend optimal time and power for use...
Subcellular tissue proteomics of hepatocellular carcinoma for molecular signature discoveryYong Yook Lee
Department of Research, Carolinas HealthCare System, Charlotte, NC, USA
J Proteome Res 10:5070-83. 2011..Here we demonstrate an efficient strategy of subcellular tissue proteomics toward molecular target discovery of one of the most complicated human disease, HCC...
Collagen-elastin ratio predicts burst pressure of arterial seals created using a bipolar vessel sealing device in a porcine modelDavid Sindram
Division of Hepatobiliary and Pancreatic Surgery, Department of General Surgery, Carolinas Medical Center, Charlotte, NC 28203, USA
Surg Endosc 25:2604-12. 2011..In this study we hypothesized that the relative ratio of the components that form the seal (collagen and elastin) determine the degree of vessel distensibility and play an equally important role in defining seal strength...
Comparison of blood vessel sealing among new electrosurgical and ultrasonic devicesWilliam L Newcomb
Division of Gastrointestinal and Minimally Invasive Surgery, Department of General Surgery, Carolinas Medical Center, 1000 Blythe Boulevard, MEB 601, Charlotte, NC 28203, USA
Surg Endosc 23:90-6. 2009..New electrosurgical and ultrasonic instruments demonstrate improved quality and efficiency in blood vessel sealing...
Effect of bacterial exposure on acellular human dermis in a rat ventral hernia modelJennifer E Keller
Division of GI and Minimally Invasive Surgery, Department of General Surgery, Carolinas Medical Center, Charlotte, North Carolina 28203, USA
J Surg Res 162:148-52. 2010..Our aim is to correlate AHD vascularization, fibroblast migration, and strength of attachment with presence of inflammatory cells in clean and contaminated fields...
Hepatic tumor ablationDavid Sindram
Section of Hepato Pancreatico Biliary Surgery, Division of GI and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, 1025 Morehead Medical Drive, Suite 300, Charlotte, NC 28204, USA
Surg Clin North Am 90:863-76. 2010..Technology is evolving rapidly, with important improvements in efficacy. The current state of ablation technology and indications for ablation are described in this review...
Guidelines for power and time variables for microwave ablation in a porcine liverWilliam W Hope
Division of Gastrointestinal and Minimally Invasive Surgery, Carolinas Medical Center, Charlotte, NC, USA
J Gastrointest Surg 12:463-7. 2008..We propose guidelines for diameters based on different time and power variables and recommend 45 W for 10 min to achieve optimal diameters at the shortest time and lowest wattage...
Real-time three-dimensional guided ultrasound targeting system for microwave ablation of liver tumours: a human pilot studyDavid Sindram
Division of Hepatobiliary Surgery, Department of General Surgery, Carolinas Medical Center, Charlotte, NC 28204, USA
HPB (Oxford) 13:185-91. 2011..This study aimed to evaluate a novel three-dimensional ultrasound (US) guidance system for use in hepatic microwave ablation (MWA)...
Pancreatic resection in a large tertiary care community-based hospital: building a successful pancreatic surgery programRyan Z Swan
Hepato Pancreato Biliary Surgery, Department of General Surgery, Carolinas Medical Center, 1025 Morehead Medical Plaza Drive, Suite 300, Charlotte, NC 28204, USA
Surg Oncol Clin N Am 20:487-500, viii. 2011....
Hepatic tumor ablation: application in a community hospital settingKwan N Lau
Hepato Pancreato Biliary Surgery, Department of General Surgery, Carolinas Medical Center, 1025 Morehead Medical Plaza Drive, Suite 300, Charlotte, NC 28204, USA
Surg Oncol Clin N Am 20:455-66, viii. 2011..This article examines the various ablative technologies and their application, as well as how these procedures can be performed safely and with optimal outcomes, in a community cancer center...
Leptin inhibits hepatocellular carcinoma proliferation via p38-MAPK-dependent signallingKyle J Thompson
Department of General Surgery, Carolinas Medical Center, Charlotte, NC 28203, USA
HPB (Oxford) 13:225-33. 2011..The aims of this study were to determine the effect(s) of leptin on HCC cell proliferation and to identify potential signalling mechanism(s) by which leptin exerts these effects...
Bile duct injury after single incision laparoscopic cholecystectomyKwan N Lau
HPB Surgery, Division of Gastrointestinal and Minimally Invasive Surgery, Department of General Surgery, Carolinas Medical Center, Charlotte, North Carolina 28203, USA
JSLS 14:587-91. 2010..With no established technique for this procedure, the safety of single incision laparoscopic cholecystectomy has not been determined...
Liver tumor ablation: percutaneous and open approachesSrikanth Padma
Section of Hepato Pancreatico Biliary Surgery, Division of GI and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, North Carolina 28203, USA
J Surg Oncol 100:619-34. 2009..This article reviews the principles behind various ablation therapies currently available for malignant liver tumors and their outcomes...
Adrenocortical carcinoma with intracaval extension to the right atrium: resection on cardiopulmonary bypassRyan Z Swan
Division of Hepatobiliary Surgery, Department of General Surgery, Carolinas Medical Center, Charlotte, NC, USA
Ann Surg Oncol 19:1275. 2012..Intraoperative ultrasound demonstrated no remaining tumor thrombus. Provisional closure was achieved with wound vac, and the next day, the patient's wound was closed primarily...
Pyogenic hepatic abscess secondary to endolumenal perforation of an ingested foreign bodyWesley A Glick
Hepato Pacreato Biliary Surgery, Department of General Surgery, Carolinas Medical Center, 1025 Morehead Medical Drive, Suite 300, Charlotte, NC 28204, USA
J Gastrointest Surg 16:885-7. 2012..Pyogenic hepatic abscess induced by foreign body perforation of the gastrointestinal tract is an increasing phenomenon. Pyogenic liver abscess in itself is a challenge to treat without the complication of a foreign body...
Perceptions of student-observers in the operating roomMary A Palilonis
Division of Research, Department of General Surgery, Carolinas Medical Center, Charlotte, North Carolina, USA
J Surg Res 170:195-201. 2011..The goal of our study was to evaluate patient, physician, and operating room (OR) staff opinions concerning student observation of surgical procedures at different levels of academic training...
Altered expression and function of regulator of G-protein signaling-17 (RGS17) in hepatocellular carcinomaEugene Sokolov
Department of General Surgery, Carolinas Medical Center, Charlotte, NC 28203, USA
Cell Signal 23:1603-10. 2011..In conclusion, these data demonstrate that, despite difficulties in measuring endogenous RGS protein expression, RGS17 is differentially expressed in HCC and plays a central role in regulating transformed hepatocyte tumorgenicity...
Novel 3-D laparoscopic magnetic ultrasound image guidance for lesion targetingDavid Sindram
Division of Hepatobiliary Surgery, Department of General Surgery, Carolinas Medical Center, Charlotte, NC 28204, USA
HPB (Oxford) 12:709-16. 2010..The aim of this study was to determine whether using magnetic positional tracking to provide three-dimensional, real-time guidance improves accuracy during laparoscopic needle placement...
Treatment of appendiceal adenocarcinoma in the United States: penetration and outcomes of current guidelinesK Christian Walters
Division of Gastrointestinal and Minimally Invasive Surgery, Carolinas Medical Center, Charlotte, North Carolina 28203, USA
Am Surg 74:1066-8. 2008..However, it appears hemicolectomy only improved survival for patients with later-stage disease. The current data raise the question of whether Stage I and II appendiceal cancer can be adequately treated with simple appendectomy...
Combined open and laparoscopic approach to chronic pain after inguinal hernia repairJennifer E Keller
Division of Gastrointestinal and Minimally Invasive Surgery, Carolinas Medical Center, Charlotte, North Carolina 28203, USA
Am Surg 74:695-700; discussion 700-1. 2008..It may be the preferred technique for the definitive management of chronic neuralgia after hernia repair...
Optimal treatment of hepatic abscessWilliam W Hope
Department of Minimally Invasive and Gastrointestinal Surgery, Carolinas Medical Center, Charlotte, North Carolina 28203, USA
Am Surg 74:178-82. 2008..40). We propose a treatment algorithm with small abscesses being treated with antibiotics alone; large, uniloculated abscess with percutaneous drainage plus antibiotics; and large, multiloculated abscessed treated with surgical therapy...
Discovery of putative pancreatic cancer biomarkers using subcellular proteomicsKimberly Q McKinney
Proteomics Laboratory for Clinical and Translational Research, Carolinas HealthCare System, Charlotte, NC, USA
J Proteomics 74:79-88. 2011..We conclude that subcellular fractionation followed by gel electrophoresis and tandem mass spectrometry is a powerful strategy for identification of differentially expressed proteins in pancreatic cancer...
Minilaparoscopic transgastric cystgastrostomyB Todd Heniford
Department of Surgery, Carolinas Medical Center, Medical Education Building 6A, Charlotte, NC 28203, USA
Am J Surg 192:248-51. 2006..A technique combining upper endoscopy with percutaneous transgastric minilaparoscopic instrumentation for the formation of pancreatic cystgastrostomy is safe and effective for the internal drainage of pancreatic pseudocysts...
Minimally invasive tension-free inguinal hernia repairDaniel D Klaristenfeld
Department of Surgery, Brown Medical School, Providence, Rhode Island, USA
Surg Technol Int 14:157-63. 2005..Laparoscopy offers lower recurrence and postoperative complication rates than standard primary open repair, with the potential for a faster and more comfortable recovery than the "tension-free" open repair...
