Research Topics
| Kai HuangSummaryAffiliation: Carnegie Mellon University Country: USA Publications
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Detail Information
Publications
Analysis of nucleotide sequence-dependent DNA binding of poly(ADP-ribose) polymerase in a purified systemKai Huang
Department of Anatomy and the Cardiovascular Research Institute, University of California-San Francisco, San Francisco, CA 94143, USA
Biochemistry 43:217-23. 2004..According to this hypothesis, the distribution of this protein-modifying enzyme in chromatin may be targeted to specific genomic loci and vary according to cell type and developmental stage...
Boosting accuracy of automated classification of fluorescence microscope images for location proteomicsKai Huang
Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA 15213 USA
BMC Bioinformatics 5:78. 2004..Building on these results, we evaluate here new classifiers and features to improve the recognition of protein subcellular location patterns in both 2D and 3D fluorescence microscope images...
HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientationsKurt A Swanson
Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, Illinois 60208 3500, USA
Nat Struct Mol Biol 11:738-46. 2004..These results not only provide insights into how multiple, unrelated transcription factors recruit the same coregulator, but also have implications for how sequence similarity searches are conducted...
From quantitative microscopy to automated image understandingKai Huang
Carnegie Mellon University, Center for Automated Learning and Discovery, Departments of Biological Sciences and Biomedical Engineering, 4400 Fifth Avenue, Pittsburgh, Pennsylvania 15213, USA
J Biomed Opt 9:893-912. 2004....
The experimental study on the radioimmunotherapy of the nasopharyngeal carcinoma overexpressing HER2/neu in nude mice model with intratumoral injection of 188Re-herceptinGuiping Li
Radiopharmaceutical Research Centre, Shanghai Institute of Applied Physics, The Chinese Academy of Sciences, Shanghai, 201800, P R China
Nucl Med Biol 32:59-65. 2005....
Characterization of the TGN exit signal of the human mannose 6-phosphate uncovering enzymePrashant Nair
Institute of Physiology, University of Zurich, Zurich, 8057, Switzerland
J Cell Sci 118:2949-56. 2005..The identification of a trans-Golgi network exit signal in its cytoplasmic tail elucidates the trafficking pathway of uncovering enzyme, a crucial player in the process of lysosomal biogenesis...
