Research Topics
Species | Brian P CasserlySummaryAffiliation: Brown University Country: USA Publications
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Detail Information
Publications
The role of natriuretic peptides in inflammation and immunityBrian P Casserly
Alpert Medical School of Brown University, Division of Pulmonary, Critical Care, and Sleep Medicine, The Memorial Hospital of Rhode Island, Pawtucket, RI, USA
Recent Pat Inflamm Allergy Drug Discov 4:90-104. 2010..Thus, the NPs and their receptors could be exploited to develop therapeutics for the inflammatory and immune responses in wide range of diseases. Also discussed are several patents regarding NPs in the present review...
Multimarker panels in sepsisBrian Casserly
Division of Pulmonary and Critical Care Medicine, The Memorial Hospital of Rhode Island, 111 Brewster Street, Pawtucket, RI 02048, USA
Crit Care Clin 27:391-405. 2011..More complex algorithms should accelerate the adoption of multimarker panels into the routine management of patients with sepsis, provided that clinicians understand the multimarker approach...
Stabilization of lung function and clinical symptoms in a patient with cystic fibrosis (CF) after institution of infliximab: a monoclonal antibody that binds tumor necrosis factor alphaBrian Casserly
Division of Pulmonary Critical Care and Sleep Medicine, Memorial Hospital of Rhode Island, 111 Brewster Street, Pawtucket, RI 02860, USA
Lung 187:149-52. 2009..This effect was sustained for 8 years while continuing to use twice-monthly infliximab...
Implementing a collaborative protocol in a sepsis intervention program: lessons learnedBrian Casserly
Memorial Hospital of Rhode Island, Brown University, 111 Brewster Street, Pawtucket, RI 02860, USA
Lung 189:11-9. 2011..However, despite a collaborative approach, the sepsis intervention program was underutilized with only 48% of the patients completing the sepsis intervention protocol...
Reducing mortality in severe sepsis and septic shockAndrew T Levinson
Division of Pulmonary, Critical Care, and Sleep Medicine, Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA
Semin Respir Crit Care Med 32:195-205. 2011....
The compensatory anti-inflammatory response syndrome (CARS) in critically ill patientsNicholas S Ward
Division of Pulmonary, Critical Care, and Sleep Medicine, The Warren Alpert Medical School of Brown University, 593 Eddy Street, APC 707, Providence, RI 02912, USA
Clin Chest Med 29:617-25, viii. 2008..Much research now suggests that the timing and relative magnitude of this response have a profound impact on patient outcomes...
Pulmonary endothelial cell signaling and functionSharon Rounds
Vascular Research Laboratory, Department of Medicine, Warren Alpert Medical School of Brown University, Providence VA Medical Center, Providence, Rhode Island 02903, USA
Trans Am Clin Climatol Assoc 119:155-67; discussion 167-9. 2008..Our data suggest that increasing intracellular adenosine is a useful therapeutic strategy against diseases characterized by increased vascular permeability...
Using serial severity scores to predict death in ICU patients: a validation study and review of the literatureEric J Gartman
Division of Pulmonary, Critical Care and Sleep Medicine, Alpert Medical School of Brown University, Providence, Rhode Island, USA
Curr Opin Crit Care 15:578-82. 2009..The present study describes the use of serial severity scores to predict death in ICU patients and compares the results with previously published literature on this topic...
Treatment options for cystic fibrosis: state of the art and future perspectivesEdmund H Sears
Alpert Medical School of Brown University, Division of Pulmonary, Critical Care, and Sleep Medicine, Rhode Island Hospital, Providence, RI, USA
Rev Recent Clin Trials 6:94-107. 2011....
Adenosine protected against pulmonary edema through transporter- and receptor A2-mediated endothelial barrier enhancementQing Lu
Vascular Research Laboratory, Providence Veterans Affairs Medical Center, Department of Medicine, Alpert Medical School of Brown University, Providence, Rhode Island 02908, USA
Am J Physiol Lung Cell Mol Physiol 298:L755-67. 2010..The data suggest that adenosine deaminase inhibition may be useful in treatment of pulmonary edema in settings of ALI...
Hemodynamic monitoring in sepsisBrian Casserly
Division of Pulmonary and Critical Care Medicine, The Memorial Hospital of Rhode Island, Pawtucket, RI, USA
Crit Care Clin 25:803-23, ix. 2009..This article examines emerging technologies as well as more established techniques used to monitor hemodynamics in sepsis and assesses their potential roles in optimization of sepsis-induced tissue hypoperfusion...
