Research Topics
Genomes and Genes
Species | C KaseSummaryAffiliation: Boston University Country: USA Publications
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Detail Information
Publications
[Diagnosis and treatment of intracerebral hemorrhage]C Kase
Department Neurology, Boston University, Massachusetts, USA
Rev Neurol 29:1330-7. 1999....- Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham StudySudha Seshadri
The National Heart Lung and Blood Institute s Framingham Heart Study, Framingham, MA, USA
BMC Med Genet 8:S15. 2007..We conducted a genome-wide association (GWA) and linkage analysis exploring the genetic basis of these endophenotypes in a community-based sample... - Intellectual decline after stroke: the Framingham StudyC S Kase
Department of Neurology, Boston University School of Medicine, Mass 02118, USA
Stroke 29:805-12. 1998..The causes and characteristics of cognitive decline after stroke are poorly defined, because most studies have relied on the diagnosis of dementia after stroke, without measurement of prestroke cognitive function... - Neurological outcomes in patients with ischemic stroke receiving enoxaparin or heparin for venous thromboembolism prophylaxis: subanalysis of the Prevention of VTE after Acute Ischemic Stroke with LMWH (PREVAIL) studyCarlos S Kase
Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA
Stroke 40:3532-40. 2009..In this PREVAIL subanalysis, we evaluate the long-term neurological outcomes associated with the use of enoxaparin compared with UFH. We also determine predictors of stroke progression... - Prevention of venous thromboembolism after ischemic strokeCarlos S Kase
Department of Neurology, Boston Medical Center, Boston, Massachusetts 02118, USA
Curr Opin Pulm Med 14:389-96. 2008..There have been recent publications that clarify some of these issues... - Advances in intracerebral haemorrhage managementC S Kase
Boston University School of Medicine, Department of Neurology, Boston, MA 02118, USA
Eur J Anaesthesiol Suppl 42:16-22. 2008..The main complication of this therapy was arterial thromboembolic events (myocardial infarction and ischaemic stroke). A phase III randomized trial has recently been completed... - Hemostatic treatment in the early stage of intracerebral hemorrhage: the recombinant factor VIIa experienceCarlos S Kase
Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA
Stroke 36:2321-2. 2005 - [Antiaggregant treatment: present and future]C S Kase
Departamento de Neurologia, Universidad de Boston, Massachusetts 02118, USA
Rev Neurol 28:1013-6. 1999..To present current information on the use of antiaggregant agents and the possibilities of their further development... - Cerebral hemorrhage after intra-arterial thrombolysis for ischemic stroke: the PROACT II trialC S Kase
Department of Neurology, Boston University School of Medicine, MA 02118, USA
Neurology 57:1603-10. 2001..To analyze the frequency, clinical characteristics, and predictors of symptomatic intracerebral hemorrhage (ICH) after intraarterial (IA) thrombolysis with recombinant pro-urokinase (r-proUK) in acute ischemic stroke... - Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral ThromboembolismA Furlan
Cerebrovascular Center, Department of Neurology, Cleveland Clinic Foundation, Ohio 44195, USA
JAMA 282:2003-11. 1999..Intravenous tissue-type plasminogen activator can be beneficial to some patients when given within 3 hours of stroke onset, but many patients present later after stroke onset and alternative treatments are needed... - Smoking and the risk of hemorrhagic stroke in menTobias Kurth
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215 1204, USA
Stroke 34:1151-5. 2003..Smoking is an established risk factor for ischemic stroke and subarachnoid hemorrhage (SAH), but the impact of smoking on intracerebral hemorrhage (ICH) is less clear... - Parental occurrence of stroke and risk of stroke in their children: the Framingham studySudha Seshadri
Department of Neurology, Boston University School of Medicine, 72 E Concord St, B602, Boston, MA 02118, USA
Circulation 121:1304-12. 2010..Data relating parental history of stroke to stroke risk in offspring remain surprisingly inconsistent, largely because of heterogeneity of study design and the absence of verified, as opposed to historical, data on parental stroke status... - Association of MRI markers of vascular brain injury with incident stroke, mild cognitive impairment, dementia, and mortality: the Framingham Offspring StudyStephanie Debette
Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA
Stroke 41:600-6. 2010..We simultaneously assessed the relation of white matter hyperintensities and BI with incident stroke, mild cognitive impairment, dementia, and mortality in a middle-aged community-based cohort... - Anticardiolipin antibodies and risk of ischemic stroke and transient ischemic attack: the Framingham cohort and offspring studyVallabh Janardhan
Department of Neurology, Boston University, Boston, Mass, USA
Stroke 35:736-41. 2004..CONCLUSIONS: Elevated serum concentrations of aCLs, independently of other cardiovascular risk factors, significantly predict the risk of future ischemic stroke and TIA in women but not in men... - Prevalence and correlates of silent cerebral infarcts in the Framingham offspring studyRohit R Das
Department of Neurology, Boston University, Boston, MA 02118, USA
Stroke 39:2929-35. 2008..8% and 17.7% depending on age, ethnicity, presence of comorbidities, and imaging techniques. We document the prevalence and risk factors associated with SCI at midlife in the community-based Framingham sample... - Treatment of warfarin-associated intracerebral hemorrhage: literature review and expert opinionMaria I Aguilar
Department of Neurology, Mayo Clinic College of Medicine, 13400 E Shea Blvd, Scottsdale, AZ 85259, USA
Mayo Clin Proc 82:82-92. 2007..Reasonable management based on expert opinion includes a wide range of additional measures to reverse anticoagulation in the absence of solid evidence... - The lifetime risk of stroke: estimates from the Framingham StudySudha Seshadri
Department of Neurology, School of Medicine, Boston University, Boston, MA 02118 2526, USA
Stroke 37:345-50. 2006..The lifetime risk (LTR) of stroke has not been reported for the United States population; such data would assist public education and health planning... - Trends in incidence, lifetime risk, severity, and 30-day mortality of stroke over the past 50 yearsRaphael Carandang
Department of Neurology, School of Medicine, Boston University, Boston, Mass 02118-2526, USA
JAMA 296:2939-46. 2006..The results of this study suggest that improved control of risk factors has lowered stroke incidence but emphasize the need for continued primary prevention efforts... - Depressive symptoms and risk of stroke: the Framingham StudyKimberly J Salaycik
Department of Neurology, Framingham Heart Study, Boston University School of Medicine, 715 Albany St, B 608B, Boston, MA 02118 2526, USA
Stroke 38:16-21. 2007..This study sought to examine whether depressive symptoms are associated with an increased risk of cerebrovascular events in a community-based sample... - Interobserver agreement in the classification of stroke in the Women's Health StudyMonika Atiya
Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass 02215-1204, USA
Stroke 34:565-7. 2003.... - Body mass index and the risk of stroke in menTobias Kurth
Brigham and Women s Hospital, Division of Preventive Medicine, 900 Commonwealth Ave East, Boston, MA 02215 1204, USA
Arch Intern Med 162:2557-62. 2002..Although obesity is an established risk factor for coronary heart disease, its role as a risk factor for stroke remains controversial... - Prospective study of body mass index and risk of stroke in apparently healthy womenTobias Kurth
Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Ave E, Boston, MA 02215 1204, USA
Circulation 111:1992-8. 2005..Several studies have found positive associations between body mass index (BMI) and stroke in men, but the association with stroke and its subtypes is less clear in women... - Smoking and risk of hemorrhagic stroke in womenTobias Kurth
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215 1204, USA
Stroke 34:2792-5. 2003..A recent study added smoking as a risk factor for intracerebral hemorrhage (ICH) in men. In contrast, the impact of smoking on ICH in women is less clear... - Brain microembolismAhmed Aly
Department of Neurology, Department of Radiology, Boston University School of Medicine, Harvard Medical School, MA, USA
J Neuroimaging 13:140-6. 2003..CONCLUSION: Small and multiple areas of acute or subacute brain infarction occasionally present with clinical features atypical for brain embolism. They can be detected by magnetic resonance DWI studies... - Alcohol consumption and functional outcome after stroke in menPamela M Rist
Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Stroke 41:141-6. 2010..Light-to-moderate alcohol consumption has been associated with reduced risk of total and ischemic stroke. However, data on the relationship between alcohol consumption and functional outcomes from stroke are sparse... - "Computed tomography-negative" intracerebral hemorrhage: case report and implications for managementAndreja S Packard
Department of Neurology, Boston University Medical Center, 715 Albany Street B-605, Boston, MA 02118, USA
Arch Neurol 60:1156-9. 2003.... - Association of plasma ADMA levels with MRI markers of vascular brain injury: Framingham offspring studyAleksandra Pikula
Boston University School of Medicine, Boston, MA, USA
Stroke 40:2959-64. 2009..The relation of plasma ADMA to subclinical vascular brain injury has not been previously studied in a middle-aged, community-based sample... - Gender differences in stroke incidence and poststroke disability in the Framingham heart studyRodica E Petrea
Department of Neurology, Boston University School of Medicine, Boston, MA 02118 2526, USA
Stroke 40:1032-7. 2009..Stroke is emerging as a major public health problem for women, as it is for men. Controversy persists regarding gender differences in stroke incidence, severity, and poststroke disability... - Cholesterol and the risk of ischemic strokeThomas S Bowman
Harvard University General Internal Medicine Fellowship Program, Veterans Affairs Boston Healthcare System Massachusetts Veterans Affairs Epidemiology, Research, and Information Center, Boston, MA 02130, USA
Stroke 34:2930-4. 2003.... - Dementia after stroke: the Framingham StudyCristina S Ivan
Department of Neurology, Boston University School of Medicine, Boston, Mass 02118-2526, USA
Stroke 35:1264-8. 2004..4; 95% CI: 1.5 to 3.9). CONCLUSIONS: Stroke increases a subject's risk of dementia as compared with age- and sex-matched controls. Primary and secondary prevention of stroke should significantly decrease the risk of all dementia... - Advances in intracerebral hemorrhage managementSeppo Juvela
Department of Neurosurgery, Helsinki University Central Hospital, Helsinki, Finland
Stroke 37:301-4. 2006 - Cerebral microbleeds: prevalence and associations with cardiovascular risk factors in the Framingham StudyTom Jeerakathil
Department of Neurology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton
Stroke 35:1831-5. 2004..CONCLUSIONS: There is a low prevalence of CMBs in the community and a strong relationship with increasing age and male sex. We found no independent relationships with cardiovascular risk factors, APOE status, brain volumes, or WMH... - The efficacy and safety of enoxaparin versus unfractionated heparin for the prevention of venous thromboembolism after acute ischaemic stroke (PREVAIL Study): an open-label randomised comparisonDavid G Sherman
Department of Medicine Neurology, University of Texas Health Science Center, San Antonio, TX 78229 3900, USA
Lancet 369:1347-55. 2007..We aimed to compare the efficacy and safety of enoxaparin with that of unfractionated heparin for patients with stroke...