Research Topics
| Andrea D CovielloSummaryAffiliation: Boston University School of Medicine Country: USA Publications
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Detail Information
Publications
Effects of graded doses of testosterone on erythropoiesis in healthy young and older menAndrea D Coviello
Section of Endocrinology, Diabetes, and Nutrition, Boston University School of Medicine, 670 Albany Street, 2nd Floor, Boston, Massachusetts 02118, USA
J Clin Endocrinol Metab 93:914-9. 2008..Erythrocytosis is a dose-limiting adverse effect of testosterone therapy, especially in older men...- Clinical meaningfulness of the changes in muscle performance and physical function associated with testosterone administration in older men with mobility limitationThomas G Travison
Section of Endocrinology, Diabetes, and Nutrition, Boston University School of Medicine and Boston Medical Center, 670 Albany Street, Boston, MA 02118, USA
J Gerontol A Biol Sci Med Sci 66:1090-9. 2011..The changes in muscle performance and physical function were evaluated in relation to participant's perception of change... - Sex hormone-binding globulin, but not testosterone, is associated prospectively and independently with incident metabolic syndrome in men: the framingham heart studyShalender Bhasin
Section of Endocrinology, Diabetes, and Nutrition, Boston University School of Medicine, Boston, MA, USA
Diabetes Care 34:2464-70. 2011..We determined whether testosterone or sex hormone-binding globulin (SHBG) is independently associated with the risk of metabolic syndrome... - Cardiac natriuretic peptides, obesity, and insulin resistance: evidence from two community-based studiesAbigail May Khan
Cardiology Division, Harvard Medical School, Boston, Massachusetts 02114, USA
J Clin Endocrinol Metab 96:3242-9. 2011..It has been suggested that obesity promotes a relative natriuretic peptide deficiency, but this has been a variable finding in prior studies and the cause is unknown... - Differences in the apparent metabolic clearance rate of testosterone in young and older men with gonadotropin suppression receiving graded doses of testosteroneAndrea D Coviello
Department of Medicine, Section of Endocrinology, Diabetes, and Nutrition, Boston University School of Medicine, Boston, Massachusetts 02118, USA
J Clin Endocrinol Metab 91:4669-75. 2006..We hypothesized that older men have lower apparent testosterone metabolic clearance rates (aMCR-T) that contribute to higher testosterone levels... - Adverse events associated with testosterone administrationShehzad Basaria
Section of Endocrinology, Diabetes, and Nutrition, Boston University School of Medicine and Boston Medical Center, Boston, Massachusetts 02118, USA
N Engl J Med 363:109-22. 2010..Testosterone supplementation has been shown to increase muscle mass and strength in healthy older men. The safety and efficacy of testosterone treatment in older men who have limitations in mobility have not been studied... - Intramuscular testosterone enanthate plus very low dosage oral levonorgestrel suppresses spermatogenesis without causing weight gain in normal young men: a randomized clinical trialBradley D Anawalt
Department of Medicine, University of Washington School of Medicine, Seattle, WA 98108, USA
J Androl 26:405-13. 2005.... - Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistanceAndrea D Coviello
Division of Endocrinology, Metabolism, and Molecular Medicine, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Tarry Building 15-709, Chicago, IL 60611-3008, USA
J Clin Endocrinol Metab 91:492-7. 2006..4-10.2; P = 0.008). CONCLUSIONS: Adolescent girls with PCOS have a higher prevalence of MBS than the general adolescent population. Hyperandrogenemia is a risk factor for MBS independent of obesity and insulin resistance... - Low-dose human chorionic gonadotropin maintains intratesticular testosterone in normal men with testosterone-induced gonadotropin suppressionAndrea D Coviello
Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98195, USA
J Clin Endocrinol Metab 90:2595-602. 2005..Extensions of this study will allow determination of the ITT concentration threshold required to maintain spermatogenesis in man... - Serum 17-hydroxyprogesterone strongly correlates with intratesticular testosterone in gonadotropin-suppressed normal men receiving various dosages of human chorionic gonadotropinJohn K Amory
Department of Medicine, University of Washington, Seattle, Washington 98195, USA
Fertil Steril 89:380-6. 2008..To determine if serum concentrations of testosterone precursors would correlate with intratesticular testosterone (ITT) concentration measured directly by testicular aspiration and allow for a less invasive means of inferring ITT... - Testosterone administration suppresses adiponectin levels in menStephanie T Page
Department of Medicine, University of Washington Medical Center, Division of Endocrinology and Metabolism, 1959 NE Pacific, Box 357138, Seattle, WA 98195, USA
J Androl 26:85-92. 2005..Furthermore, supraphysiologic T administration results in decreased adiponectin levels. Our data support the hypothesis that T, its metabolites, or both directly suppress adipocyte production of adiponectin... - A single dose of the potent gonadotropin-releasing hormone antagonist acyline suppresses gonadotropins and testosterone for 2 weeks in healthy young menKaren L Herbst
Department of Medicine, Division of Endocrinology, Metabolism, and Molecular Medicine, Charles R Drew University, Los Angeles, California 90059, USA
J Clin Endocrinol Metab 89:5959-65. 2004..A twice monthly injection of acyline could be used as a potent suppressor of the GnRH axis to advance the development of a hormonal male contraceptive or for treatment of hormonally dependent disease... - Intratesticular testosterone concentrations comparable with serum levels are not sufficient to maintain normal sperm production in men receiving a hormonal contraceptive regimenAndrea D Coviello
Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA
J Androl 25:931-8. 2004..Intratesticular androgenic bioactivity was higher than ITT during treatment, suggesting that other androgens may be prevalent in the low-ITT environment... - Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts male aging studyHenry A Feldman
New England Research Institutes, Watertown, Massachusetts 02472, USA
J Clin Endocrinol Metab 87:589-98. 2002..The paradoxical finding that longitudinal age trends were steeper than cross-sectional trends suggests that incident poor health may accelerate the age-related decline in androgen levels...