Kazem M Azadzoi

Summary

Affiliation: Boston University
Country: USA

Publications

  1. ncbi Molecular reactions and ultrastructural damage in the chronically ischemic bladder
    Kazem M Azadzoi
    Department of Pathology, Veterans Affairs Boston Healthcare System, Boston, Massachusetts, USA
    J Urol 186:2115-22. 2011
  2. ncbi Human bladder smooth muscle cell damage in disturbed oxygen tension
    Kazem M Azadzoi
    Department of Urology, Boston University School of Medicine, Boston, MA, USA
    Urology 78:967.e9-15. 2011
  3. ncbi Oxidative modification of mitochondrial integrity and nerve fiber density in the ischemic overactive bladder
    Kazem M Azadzoi
    Department of Pathology, Veterans Affairs Boston Healthcare System, Boston, Massachusetts, USA
    J Urol 183:362-9. 2010
  4. ncbi Oxidative stress and neurodegeneration in penile ischaemia
    Kazem M Azadzoi
    VA Boston Healthcare System and Boston University School of Medicine, and Department of Urology, Harvard Medical School, Boston, MA, USA
    BJU Int 105:404-10. 2010
  5. ncbi Effects of ischemia on tachykinin-containing nerves and neurokinin receptors in the rabbit bladder
    Kazem M Azadzoi
    Department of Urology, VA Boston Healthcare System, Boston, Massachusetts, USA
    Urology 71:979-83. 2008
  6. ncbi Oxidative stress and neurodegeneration in the ischemic overactive bladder
    Kazem M Azadzoi
    Department of Urology, Veterans Affairs Boston Healthcare System, Boston, Massachusetts, USA
    J Urol 178:710-5. 2007
  7. ncbi Editorial comment on: Immunohistochemical distribution of cyclic GMP-dependent protein kinase-1 in human prostate tissue
    Kazem M Azadzoi
    Boston University School of Medicine, VA Boston Healthcare System, Boston, MA, USA
    Eur Urol 52:501-2. 2007
  8. ncbi Vasculogenic erectile dysfunction: beyond the haemodynamic changes
    Kazem M Azadzoi
    Urology Research, VA Boston Healthcare System and Boston University Medical School, Boston, MA 02130, USA
    BJU Int 97:11-6. 2006
  9. ncbi Oxidative stress in arteriogenic erectile dysfunction: prophylactic role of antioxidants
    Kazem M Azadzoi
    Department of Urology, Boston University School of Medicine and Veterans Affairs Boston Healthcare System, Boston, Massachusetts, USA
    J Urol 174:386-93. 2005
  10. ncbi Alteration of urothelial-mediated tone in the ischemic bladder: role of eicosanoids
    Kazem M Azadzoi
    Urology Research 151, Boston University School of Medicine and VA Boston Medical Center, 150 South Huntington Avenue, Boston, MA 02130, USA
    Neurourol Urodyn 23:258-64. 2004

Collaborators

Detail Information

Publications19

  1. ncbi Molecular reactions and ultrastructural damage in the chronically ischemic bladder
    Kazem M Azadzoi
    Department of Pathology, Veterans Affairs Boston Healthcare System, Boston, Massachusetts, USA
    J Urol 186:2115-22. 2011
    ..Clinical and basic research data suggest that pelvic ischemia may contribute to bladder overactivity. We characterized the molecular and ultrastructural reactions of the chronically ischemic bladder...
  2. ncbi Human bladder smooth muscle cell damage in disturbed oxygen tension
    Kazem M Azadzoi
    Department of Urology, Boston University School of Medicine, Boston, MA, USA
    Urology 78:967.e9-15. 2011
    ..To characterize human bladder smooth muscle cell reactions to disturbed oxygen tension. Clinical studies have shown a close correlation between bladder ischemia and lower urinary tract symptoms in elderly patients...
  3. ncbi Oxidative modification of mitochondrial integrity and nerve fiber density in the ischemic overactive bladder
    Kazem M Azadzoi
    Department of Pathology, Veterans Affairs Boston Healthcare System, Boston, Massachusetts, USA
    J Urol 183:362-9. 2010
    ..To our knowledge the mechanism of neurodegeneration in the overactive bladder remains unknown. We examined mitochondrial integrity and searched for markers of oxidative neural injury in the ischemic overactive bladder...
  4. ncbi Oxidative stress and neurodegeneration in penile ischaemia
    Kazem M Azadzoi
    VA Boston Healthcare System and Boston University School of Medicine, and Department of Urology, Harvard Medical School, Boston, MA, USA
    BJU Int 105:404-10. 2010
    ....
  5. ncbi Effects of ischemia on tachykinin-containing nerves and neurokinin receptors in the rabbit bladder
    Kazem M Azadzoi
    Department of Urology, VA Boston Healthcare System, Boston, Massachusetts, USA
    Urology 71:979-83. 2008
    ..The goal of this study was to examine the effects of bladder ischemia on tachykinin (TK) containing sensory nerves and neurokinin receptors (NKR) in a rabbit model...
  6. ncbi Oxidative stress and neurodegeneration in the ischemic overactive bladder
    Kazem M Azadzoi
    Department of Urology, Veterans Affairs Boston Healthcare System, Boston, Massachusetts, USA
    J Urol 178:710-5. 2007
    ..The central and peripheral nervous systems are highly sensitive to ischemia and oxidative stress. We searched for markers of oxidative injury and examined neural density in the rabbit ischemic overactive bladder...
  7. ncbi Editorial comment on: Immunohistochemical distribution of cyclic GMP-dependent protein kinase-1 in human prostate tissue
    Kazem M Azadzoi
    Boston University School of Medicine, VA Boston Healthcare System, Boston, MA, USA
    Eur Urol 52:501-2. 2007
  8. ncbi Vasculogenic erectile dysfunction: beyond the haemodynamic changes
    Kazem M Azadzoi
    Urology Research, VA Boston Healthcare System and Boston University Medical School, Boston, MA 02130, USA
    BJU Int 97:11-6. 2006
  9. ncbi Oxidative stress in arteriogenic erectile dysfunction: prophylactic role of antioxidants
    Kazem M Azadzoi
    Department of Urology, Boston University School of Medicine and Veterans Affairs Boston Healthcare System, Boston, Massachusetts, USA
    J Urol 174:386-93. 2005
    ..We searched for markers of oxidative stress in cavernous ischemia and examined the effect of long-term antioxidant intake on arteriogenic erectile dysfunction (ED) in the rabbit...
  10. ncbi Alteration of urothelial-mediated tone in the ischemic bladder: role of eicosanoids
    Kazem M Azadzoi
    Urology Research 151, Boston University School of Medicine and VA Boston Medical Center, 150 South Huntington Avenue, Boston, MA 02130, USA
    Neurourol Urodyn 23:258-64. 2004
    ..Previously we showed that ischemia alters bladder smooth muscle contractility in the rabbit. This study investigates the role of urothelium and eicosanoid-release in ischemic bladder smooth muscle instability...
  11. ncbi Effect of chronic ischemia on constitutive and inducible nitric oxide synthase expression in erectile tissue
    Kazem M Azadzoi
    Boston University School of Medicine, Boston, Massachusetts, USA
    J Androl 25:382-8. 2004
    ..Ischemically altered NOS expression may be of great pathophysiologic importance in atherosclerosis-induced ED. These data may provide further insight into the mechanism of arteriogenic ED...
  12. ncbi Chronic ischemia increases prostatic smooth muscle contraction in the rabbit
    Kazem M Azadzoi
    Department of Urology, Boston University School of Medicine, Massachusetts 02130, USA
    J Urol 170:659-63. 2003
    ..Increased smooth muscle tone and structural changes in the ischemic prostate may suggest a role for prostate ischemia in resistance to urinary flow independent of prostate size...
  13. ncbi Vasculogenic erectile dysfunction: newer therapeutic strategies
    Mike B Siroky
    Boston Veterans Administration Medical Center, 150 South Huntington Ave, Room A4 43, Boston, Massachusetts 02130, USA
    J Urol 170:S24-9; discussion S29-30. 2003
    ..A review of vasculogenic ED may further our understanding of the underlying pathophysiology and help develop more effective curative therapy...
  14. ncbi Increased leukotriene and prostaglandin release, and overactivity in the chronically ischemic bladder
    Kazem M Azadzoi
    Department of Urology, Boston University School of Medicine, Boston, MA, USA
    J Urol 169:1885-91. 2003
    ..PGs modulate smooth muscle contractility in the healthy bladder. However, under ischemic conditions leukotrienes dominate bladder tone and appear to have a leading role in increased smooth muscle contraction and bladder overactivity...
  15. ncbi Regulation of blood flow and microcirculation resistance in rabbit bladder
    Robert Kozlowski
    Department of Urology, Boston University School of Medicine and Veterans Affairs Healthcare System, Boston, Massachusetts, USA
    J Urol 168:1608-14. 2002
    ..Mechanical changes in bladder wall and vasculature shape may also contribute to changes in microcirculation resistance...
  16. ncbi Blood flow, pressure and compliance in the male human bladder
    Richard T Kershen
    Department of Urology, Boston University School of Medicine, Massachusetts, USA
    J Urol 168:121-5. 2002
    ..Decreased bladder blood flow and decreased bladder wall compliance correlated strongly, suggesting that ischemia may lead to structural changes in the bladder wall...
  17. ncbi Pilot study of the endothelin-A receptor selective antagonist BMS-193884 for the treatment of erectile dysfunction
    Noel N Kim
    Department of Urology, Boston University School of Medicine, Massachusetts 02118, USA
    J Androl 23:76-83. 2002
    ..The disparity between the laboratory and clinical studies suggests that there may be differences between species with regard to the role of endothelin in erectile function...
  18. ncbi Effect of chronic ischemia on bladder structure and function
    Kazem M Azadzoi
    Urology Research, Boston University School of Medicine, MA 02130, USA
    Adv Exp Med Biol 539:271-80. 2003
    ....
  19. ncbi Neurologic factors in female sexual function and dysfunction
    Kazem M Azadzoi
    Department of Urology, Veterans Affairs Boston Healthcare System and Boston University School of Medicine, Boston, Massachusetts, USA
    Korean J Urol 51:443-9. 2010
    ..In this review, we summarize neural regulation of sexual function and neurological causes of sexual dysfunction in women...