Andrew Lees

Summary

Affiliation: Biosynexus Incorporated
Country: USA

Publications

  1. ncbi Versatile and efficient synthesis of protein-polysaccharide conjugate vaccines using aminooxy reagents and oxime chemistry
    Andrew Lees
    Biosynexus Incorporated, 9119 Gaither Rd, Gaithersburg, MD 20877, USA
    Vaccine 24:716-29. 2006
  2. ncbi Immunogenicity and efficacy of Cryptococcus neoformans capsular polysaccharide glucuronoxylomannan peptide mimotope-protein conjugates in human immunoglobulin transgenic mice
    Robert W Maitta
    Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Infect Immun 72:196-208. 2004
  3. ncbi Therapeutic efficacy of a conjugate vaccine containing a peptide mimotope of cryptococcal capsular polysaccharide glucuronoxylomannan
    Kausik Datta
    Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Clin Vaccine Immunol 15:1176-87. 2008

Collaborators

  • Kausik Datta
  • Liise-Anne Pirofski
  • Robert W Maitta
  • Liise Anne Pirofski
  • Shelley Sims Belouski

Detail Information

Publications3

  1. ncbi Versatile and efficient synthesis of protein-polysaccharide conjugate vaccines using aminooxy reagents and oxime chemistry
    Andrew Lees
    Biosynexus Incorporated, 9119 Gaither Rd, Gaithersburg, MD 20877, USA
    Vaccine 24:716-29. 2006
    ..The primary immune response could be boosted, indicating that the polysaccharide conjugate had characteristics of a T cell dependent antigen...
  2. ncbi Immunogenicity and efficacy of Cryptococcus neoformans capsular polysaccharide glucuronoxylomannan peptide mimotope-protein conjugates in human immunoglobulin transgenic mice
    Robert W Maitta
    Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Infect Immun 72:196-208. 2004
    ..neoformans infections...
  3. ncbi Therapeutic efficacy of a conjugate vaccine containing a peptide mimotope of cryptococcal capsular polysaccharide glucuronoxylomannan
    Kausik Datta
    Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Clin Vaccine Immunol 15:1176-87. 2008
    ..Taken together, our data suggest that a vaccine could hold promise in the setting of chronic cryptococcosis, and that vaccine efficacy could depend on immunomodulation and augmentation of the natural immune response of the host...