Jan Rohozinski

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. ncbi Spermatogenesis associated retrogenes are expressed in the human ovary and ovarian cancers
    Jan Rohozinski
    Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX, USA
    PLoS ONE 4:e5064. 2009
  2. ncbi UTP14c is a recently acquired retrogene associated with spermatogenesis and fertility in man
    Jan Rohozinski
    Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas 77030, USA
    Biol Reprod 74:644-51. 2006
  3. ncbi Utp14b: a unique retrogene within a gene that has acquired multiple promoters and a specific function in spermatogenesis
    Ming Zhao
    Department of Experimental Radiation Oncology, University of Texas M D Anderson Cancer Center, Box 066, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Dev Biol 304:848-59. 2007
  4. ncbi Oocyte-specific G-protein-coupled receptor 3 (GPR3): no perturbations found in 82 women with premature ovarian failure (first report)
    Ertug Kovanci
    Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas, USA
    Fertil Steril 90:1269-71. 2008
  5. ncbi Does expression of the retrogene UTP14c in the ovary pre-dispose women to ovarian cancer?
    Jan Rohozinski
    Institute for Regenerative Medicine, Wake Forest School of Medicine, Winston Salem, NC 27157, USA
    Med Hypotheses 78:446-9. 2012
  6. ncbi The mouse juvenile spermatogonial depletion (jsd) phenotype is due to a mutation in the X-derived retrogene, mUtp14b
    Jan Rohozinski
    Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 101:11695-700. 2004
  7. ncbi Growth differentiating factor-9 mutations may be associated with premature ovarian failure
    Ertug Kovanci
    Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas 77030, USA
    Fertil Steril 87:143-6. 2007

Detail Information

Publications7

  1. ncbi Spermatogenesis associated retrogenes are expressed in the human ovary and ovarian cancers
    Jan Rohozinski
    Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX, USA
    PLoS ONE 4:e5064. 2009
    ..However, it is by far the most lethal. This is generally attributed to the absence of easily detectable markers specific to ovarian cancers that can be used for early diagnosis and specific therapeutic targets...
  2. ncbi UTP14c is a recently acquired retrogene associated with spermatogenesis and fertility in man
    Jan Rohozinski
    Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas 77030, USA
    Biol Reprod 74:644-51. 2006
    ..The novel evolution of retroposed UTP14 genes supports the hypothesis that retrogenes play an important role in evolution via regulation of male reproductive fitness...
  3. ncbi Utp14b: a unique retrogene within a gene that has acquired multiple promoters and a specific function in spermatogenesis
    Ming Zhao
    Department of Experimental Radiation Oncology, University of Texas M D Anderson Cancer Center, Box 066, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Dev Biol 304:848-59. 2007
    ..The novel cell-type-specific promoter for Utp14b likely evolved later, as the protein may have acquired a germ cell-specific function in spermatid development...
  4. ncbi Oocyte-specific G-protein-coupled receptor 3 (GPR3): no perturbations found in 82 women with premature ovarian failure (first report)
    Ertug Kovanci
    Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas, USA
    Fertil Steril 90:1269-71. 2008
    ..None of the 82 POF samples showed perturbations of significance. We conclude that perturbations in GPR3 are not a common explanation for POF in this population...
  5. ncbi Does expression of the retrogene UTP14c in the ovary pre-dispose women to ovarian cancer?
    Jan Rohozinski
    Institute for Regenerative Medicine, Wake Forest School of Medicine, Winston Salem, NC 27157, USA
    Med Hypotheses 78:446-9. 2012
    ....
  6. ncbi The mouse juvenile spermatogonial depletion (jsd) phenotype is due to a mutation in the X-derived retrogene, mUtp14b
    Jan Rohozinski
    Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030, USA
    Proc Natl Acad Sci U S A 101:11695-700. 2004
    ..In jsd homozygotes, which lack a functional copy of Utp14b, insufficient production of rRNA quickly leads to a cessation of spermatogenesis...
  7. ncbi Growth differentiating factor-9 mutations may be associated with premature ovarian failure
    Ertug Kovanci
    Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas 77030, USA
    Fertil Steril 87:143-6. 2007
    ..To determine whether perturbations of the growth differentiating factor-9 (GDF9) gene are associated with premature ovarian failure (POF)...