Research Topics
Genomes and Genes | Heather L LaMarcaSummaryAffiliation: Baylor College of Medicine Country: USA Publications
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Publications
Prospective isolation and characterization of committed and multipotent progenitors from immortalized mouse mammary epithelial cells with morphogenic potentialFrances S Kittrell
Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, KS 66160, USA
Breast Cancer Res 13:R41. 2011....- Estrogen regulation of mammary gland development and breast cancer: amphiregulin takes center stageHeather L LaMarca
Department of Molecular and Cellular Biology, Baylor College of Medicine, Baylor Plaza, Houston, TX 77030, USA
Breast Cancer Res 9:304. 2007..These studies implicate a critical role for amphiregulin in mammary stem cell differentiation as well as breast cancer initiation and progression... - Marinobufagenin impairs first trimester cytotrophoblast differentiationH L Lamarca
Department of Microbiology and Immunology, Tulane University Health Sciences Center, New Orleans, LA, USA
Placenta 27:984-8. 2006..Elucidating the mechanisms by which MBG impairs placental development may increase our understanding of fetal and maternal pathologies associated with preeclampsia... - CCAAT/enhancer binding protein beta regulates stem cell activity and specifies luminal cell fate in the mammary glandHeather L LaMarca
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA
Stem Cells 28:535-44. 2010..These findings have critical implications for understanding both stem cell biology and the etiology of different breast cancer subtypes... - Altered differentiation and paracrine stimulation of mammary epithelial cell proliferation by conditionally activated SmoothenedAdriana P Visbal
Program in Developmental Biology Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
Dev Biol 352:116-27. 2011..In addition, these results also have potential implications for the interpretation of proliferative phenotypes commonly observed in other organs as a consequence of hedgehog signaling activation... - Synergistic inhibition of human cytomegalovirus replication by interferon-alpha/beta and interferon-gammaBruno Sainz
Department of Microbiology and Immunology, Program in Molecular Pathogenesis and Immunity, Tulane University Health Sciences Center, 1430 Tulane Avenue, SL 38, New Orleans, LA 70112, USA
Virol J 2:14. 2005..To determine whether this phenomenon is shared by other herpesviruses, we investigated the effects of IFNs on human cytomegalovirus (HCMV) replication... - Epidermal growth factor-stimulated extravillous cytotrophoblast motility is mediated by the activation of PI3-K, Akt and both p38 and p42/44 mitogen-activated protein kinasesHeather L LaMarca
Department of Microbiology and Immunology, Tulane University Health Sciences Center, New Orleans, LA, USA
Hum Reprod 23:1733-41. 2008..Evidence suggests that the potent mitogen epidermal growth factor (EGF) regulates cytotrophoblast (CTB) differentiation and invasion during early pregnancy... - SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migrationWeiwen Long
Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030 USA
Mol Cell 37:321-32. 2010..Our study also reveals that a nuclear receptor coactivator can act in the periphery of a cell to directly mediate activation of an enzyme... - Minireview: hormones and mammary cell fate--what will I become when I grow up?Heather L LaMarca
Department of Molecular and Cellular Biology, DeBakey Building M638a, Houston, Texas 77030, USA
Endocrinology 149:4317-21. 2008..Here we review recent studies on the involvement of hormone receptors and several transcription factors in mammary stem/progenitor cell differentiation and lineage commitment... - Kaposi's sarcoma associated herpesvirus G-protein coupled receptor activation of cyclooxygenase-2 in vascular endothelial cellsBryan D Shelby
Department of Microbiology and Immunology, Tulane University Health Sciences Center, New Orleans, LA 70112, USA
Virol J 4:87. 2007.... - Ovarian cancers overexpress the antimicrobial protein hCAP-18 and its derivative LL-37 increases ovarian cancer cell proliferation and invasionSeth B Coffelt
Department of Microbiology and Immunology, Tulane University, New Orleans, LA, USA
Int J Cancer 122:1030-9. 2008..These data provide further evidence of the existing relationship between pro-inflammatory molecules and ovarian cancer progression... - Permissive human cytomegalovirus infection of a first trimester extravillous cytotrophoblast cell lineHeather L LaMarca
Interdisciplinary Program in Molecular and Cellular Biology, Tulane University Health Sciences Center, New Orleans, LA, USA
Virol J 1:8. 2004..Our findings suggest that these cells may serve as useful tools for future mechanistic studies of HCMV pathogenesis during early pregnancy... - Three-dimensional growth of extravillous cytotrophoblasts promotes differentiation and invasionH L Lamarca
Department of Microbiology and Immunology, Tulane University Health Sciences Center, New Orleans, LA, USA
Placenta 26:709-20. 2005..These findings suggest that when cultured in 3-D, SGHPL-4 cells closely mimic differentiating in utero CTBs, providing a novel approach for the in vitro study of the molecular mechanisms that regulate CTB differentiation and invasion... - Human cytomegalovirus-induced inhibition of cytotrophoblast invasion in a first trimester extravillous cytotrophoblast cell lineH L Lamarca
Department of Microbiology and Immunology, Tulane University Health Sciences Center, 1430 Tulane Avenue SL-38, New Orleans, LA 70112, USA
Placenta 27:137-47. 2006..Elucidating the mechanisms by which HCMV impairs placentation may be key in understanding fetal and maternal pathologies associated with intrauterine HCMV infection...