Research Topics
| William Paul GlezenSummaryAffiliation: Baylor College of Medicine Country: USA Publications
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Detail Information
Publications
Influenza vaccination for healthy childrenW Paul Glezen
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas 77030 3498, USA
Curr Opin Infect Dis 15:283-7. 2002..The new live attenuated nasal spray influenza vaccine is particularly effective in healthy children who would benefit most from universal immunization...
Impact of respiratory virus infections on persons with chronic underlying conditionsW P Glezen
Department of Microbiology and Immunology, Baylor College of Medicine, Houston, Tex 77030, USA
JAMA 283:499-505. 2000..Development of new approaches for prevention of acute respiratory tract conditions requires studies of the etiologies of infections and quantification of the risk of hospitalization for vulnerable patients...
A response to strategy #2: streamlining the regulatory processW Paul Glezen
Influenza Research Center, Department of Molecular Virology, Baylor College of Medicine, Houston, TX 77030, USA
Clin Infect Dis 42:S141-4. 2006..Regulatory bodies must work with manufacturers to facilitate implementation of new production practices, to ensure steady expansion of the supply of safe and effective vaccines...
Modifying clinical practices to manage influenza in children effectivelyWilliam Paul Glezen
Department of Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza, MS BCM 280, Houston, TX 77030, USA
Pediatr Infect Dis J 27:738-43. 2008..The neuraminidase inhibitors also have shown efficacy against influenza B infection and exhibit less viral resistance than the older adamantane antiviral class...
Control of influenzaW Paul Glezen
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas 77030 3498, USA
Tex Heart Inst J 31:39-41. 2004..The availability of the live, attenuated, cold-adapted nasal spray vaccine should facilitate this goal...
Cold-adapted, live attenuated influenza vaccineW Paul Glezen
Department of Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza, Mail Stop BCM 280, Houston, TX 77030 3498, USA
Expert Rev Vaccines 3:131-9. 2004..Use of CAIV-T in children will not only decrease the risk of serious disease, but also dampen the spread of the virus in the community and reduce exposure of patients who are at high risk of complications and death...
Session IV. Ethical, liability and regulatory issuesW Paul Glezen
Molecular Virology, Microbiology and Pediatric Influenza Research Center, Baylor College of Medicine, One Baylor Plaza Suite 221 D, Houston, TX 77030, USA
Vaccine 21:3501-2. 2003
Effect of maternal antibodies on the infant immune responseW Paul Glezen
Department of Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza, Mail Stop BCM 280, Houston, TX 77030, USA
Vaccine 21:3389-92. 2003..No evidence for the development of fetal tolerance after immunization during pregnancy has occurred subsequently in infants following active vaccination...
Influenza virus in pediatric patients. IntroductionW Paul Glezen
Department of Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza, Mail Stop BCM-240, Houston, TX 77030-3498, USA
Semin Pediatr Infect Dis 13:69-70. 2002
Prevention of acute otitis media by prophylaxis and treatment of influenza virus infectionsW P Glezen
Molecular Virology and Microbiology, Influenza Research Center at Baylor College of Medicine, One Baylor Plaza, Suite 221D, Houston, TX 77030, USA
Vaccine 19:S56-8. 2000..Influenza produces high morbidity in children that could be averted by universal immunization with attenuated nasal spray vaccine...
The changing epidemiology of respiratory syncytial virus and influenza: impetus for new control measuresW Paul Glezen
Departments of Molecular Virology and Microbiology and of Pediatrics, Baylor College of Medicine, Houston, TX, USA
Pediatr Infect Dis J 23:S202-6. 2004..New approaches to control will be necessary to reduce impact of these infections. These include earlier availability of influenza vaccine each autumn and use of antivirals and new vaccines for RSV...
Universal influenza vaccination and live attenuated influenza vaccination of childrenW Paul Glezen
Department of MVM, Baylor College of Medicine, Houston, TX 77030, USA
Pediatr Infect Dis J 27:S104-9. 2008..Systematic delivery of influenza vaccine in school-based and workplace-based clinics would greatly enhance the control of epidemic influenza and help prepare for the next pandemic...
Improving influenza immunization in pregnant women and healthcare workersMelanie E Mouzoon
Kelsey Seybold Clinic, Houston, TX, USA
Am J Manag Care 16:209-16. 2010..To evaluate the effect of several strategies to increase influenza immunization in a multispecialty clinic...
Trivalent live attenuated intranasal influenza vaccine administered during the 2003-2004 influenza type A (H3N2) outbreak provided immediate, direct, and indirect protection in childrenPedro A Piedra
Baylor College of Medicine, Department of Molecular Virology and Microbiology, Room 248E, One Baylor Plaza, Houston, TX 77030, USA
Pediatrics 120:e553-64. 2007..The objective of this study was to determine the effectiveness of influenza vaccines for healthy school-aged children when administered during the influenza outbreak...
Live attenuated influenza vaccine, trivalent, is safe in healthy children 18 months to 4 years, 5 to 9 years, and 10 to 18 years of age in a community-based, nonrandomized, open-label trialPedro A Piedra
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas 77030, USA
Pediatrics 116:e397-407. 2005....
Safety of influenza vaccination during pregnancyFlor M Munoz
Baylor College of Medicine, Department of Pediatrics and Molecular Virology, Houston, TX 77030, USA
Am J Obstet Gynecol 192:1098-106. 2005..The purpose of this study was to evaluate the safety of influenza vaccine that is administered in the second or third trimester of gestation...
Safety and immunogenicity of respiratory syncytial virus purified fusion protein-2 vaccine in pregnant womenFlor M Munoz
Department of Molecular Virology and Microbiology, and Pediatrics, Baylor College of Medicine, Influenza Reseach Center, One Baylor Plaza Suite 221 D, MS BCM 280, Houston, TX 77030, USA
Vaccine 21:3465-7. 2003..infants of placebo recipients. Vaccine specific anti-F IgA and IgG concentrations in breast milk were higher in mothers who received RSV-PFP-2...
Direct and indirect effectiveness of influenza vaccination delivered to children at school preceding an epidemic caused by 3 new influenza virus variantsW Paul Glezen
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas 77030, USA
J Infect Dis 202:1626-33. 2010..This field trial examines the effectiveness of school-based clinics for vaccine delivery before an epidemic caused by 3 new influenza virus variants not contained in the vaccine...
Correlates of immunity to respiratory syncytial virus (RSV) associated-hospitalization: establishment of minimum protective threshold levels of serum neutralizing antibodiesPedro A Piedra
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Rm 248E, One Baylor Plaza, Houston, TX, USA
Vaccine 21:3479-82. 2003..To determine if respiratory syncytial virus (RSV) specific, serum antibody titers correlate with protection against RSV associated-hospitalization at all ages...
Herd immunity in adults against influenza-related illnesses with use of the trivalent-live attenuated influenza vaccine (CAIV-T) in childrenPedro A Piedra
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Rm 248E, One Baylor Plaza, Houston, TX 77030, USA
Vaccine 23:1540-8. 2005..Vaccination of approximately 20-25% of children, 1.5-18 years of age in the intervention communities resulted in an indirect protection of 8-18% against MAARI in adults > or =35 years of age...
Asthma, influenza, and vaccinationW Paul Glezen
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA
J Allergy Clin Immunol 118:1199-206; quiz 1207-8. 2006..Universal vaccination of all children in school-based clinics will facilitate control of epidemic influenza and provide an infrastructure for control of future influenza pandemics...
Herd protection against influenzaW Paul Glezen
MVM Department, Baylor College of Medicine, One Baylor Plaza, MS BCM 280, Houston, TX 77030, United States
J Clin Virol 37:237-43. 2006..School-based clinics could provide a platform for rapid deployment of vaccine accessible to all segments of the population. This strategy could be critical for control of pandemic influenza...
Medically attended pediatric influenza during the resurgence of the Victoria lineage of influenza B virusLadonna K Hite
Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
Int J Infect Dis 11:40-7. 2007..During the 2002-2003 season, a new variant of influenza B co-circulated with influenza A viruses. This study examines the characteristics and outcomes of children with influenza A and B virus infection vs. other acute respiratory illnesses...
Commentary: benefits of influenza vaccine in US elderly--new studies raise questionsW Paul Glezen
Department of Molecular Virology and Microbiology, and Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
Int J Epidemiol 35:352-3. 2006
New vaccines for old diseases: trivalent cold-adapted influenza vaccineW Paul Glezen
Department of Molecular Virology and Microbiology, and Pediatrics, Baylor College of Medicine, Houston, TX 77030-3498, USA
Pediatr Ann 33:545-50. 2004..The number of excess deaths is expected to double within the next 25 years if control methods are not intensified. CAIV-T may become an important adjunct to control measures and can facilitate influenza pandemic preparedness...
Respiratory viral infections in patients with chronic, obstructive pulmonary diseaseJ David Beckham
Department of Medicine, Baylor College of Medicine and Ben Taub General Hospital, One Baylor Plaza, Houston, TX 77030, USA
J Infect 50:322-30. 2005..CONCLUSIONS: Respiratory viral infections are commonly associated with acute respiratory illness in COPD patients, and the use of RT-PCR assays significantly increases the ability to diagnose these infections...
