Research Topics
Species | J BanchereauSummaryAffiliation: Baylor University Medical Center Country: USA Publications
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Detail Information
Publications
Immunobiology of dendritic cellsJ Banchereau
Baylor Institute for Immunology Research, Dallas, Texas 75204, USA
Annu Rev Immunol 18:767-811. 2000..Although our understanding of DC biology is still in its infancy, we are now beginning to use DC-based immunotherapy protocols to elicit immunity against cancer and infectious diseases...
Immune and clinical responses in patients with metastatic melanoma to CD34(+) progenitor-derived dendritic cell vaccineJ Banchereau
Baylor Institute for Immunology Research, Dallas, Texas 75204, USA
Cancer Res 61:6451-8. 2001..Regression of >1 tumor metastases were observed in seven of these patients. The overall immunity to MelAgs after DC vaccination is associated with clinical outcome (P = 0.015)...
Sensing pathogens and tuning immune responsesB Pulendran
Baylor Institute for Immunology Research, 3434 Live Oak, Dallas, TX 75204, USA
Science 293:253-6. 2001....
Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosusP Blanco
Baylor Institute for Immunology Research, Dallas, TX 75204, USA
Science 294:1540-3. 2001..Thus, unabated induction of DCs by IFN-alpha may drive the autoimmune response in SLE...
Lipopolysaccharides from distinct pathogens induce different classes of immune responses in vivoB Pulendran
Baylor Institute for Immunology Research, Dallas, TX 75204, USA
J Immunol 167:5067-76. 2001..coli LPS, but not P. gingivalis LPS. Therefore, LPS from different bacteria activate DC subsets to produce different cytokines, and induce distinct types of adaptive immunity in vivo...
Evidence and a novel hypothesis for the role of dendritic cells and Porphyromonas gingivalis in adult periodontitisC W Cutler
Department of Biomedical Sciences, Baylor College of Dentistry TAMUS, Dallas, Texas 75266 00677, USA
J Periodontal Res 34:406-12. 1999..Many questions about the role of P. gingivalis-sensitized DCs in adult periodontitis, and of the parallels between adult periodontitis and CHS, however, remain to be answered...
Dendritic cells and immunity against cancerK Palucka
Baylor Institute for Immunology Research, Baylor University Medical Center, Dallas, TX, USA
J Intern Med 269:64-73. 2011..We foresee that these novel cancer vaccines will be used as monotherapy in patients with resected disease and in combination with drugs targeting regulatory/suppressor pathways in patients with metastatic disease...
Interleukin 15 skews monocyte differentiation into dendritic cells with features of Langerhans cellsM Mohamadzadeh
Baylor Institute for Immunology Research, Baylor University Medical Center, Dallas, TX 75204, USA
J Exp Med 194:1013-20. 2001..Thus, our results demonstrate a novel pathway in monocyte differentiation into dendritic cells...
Dendritic cells as melanoma vaccinesJ Banchereau
Baylor Institute for Immunology Research, Dallas, TX 75204, USA
Dev Biol (Basel) 116:147-56; discussion 179-86. 2004
Increased frequency of pre-germinal center B cells and plasma cell precursors in the blood of children with systemic lupus erythematosusE Arce
Baylor Institute for Immunology Research, Dallas, TX 75204, USA
J Immunol 167:2361-9. 2001..Thus, SLE is associated with major blood B cell subset alterations...
Dendritic cells: a link between innate and adaptive immunityK Palucka
Baylor Institute for Immunology Research, Dallas, Texas 75246, USA
J Clin Immunol 19:12-25. 1999..Although our understanding of DC biology is still in its infancy, we are now in a position to use DC-based immunotherapy protocols to treat cancer and infectious diseases...
Modulating the immune response with dendritic cells and their growth factorsB Pulendran
Baylor Institute for Immunology, Dallas, TX 75204, USA
Trends Immunol 22:41-7. 2001..A model is proposed that links together factors such as the pathogen, microenvironment, DCs and T cells in a mechanism that results in a flexible determination of T-cell polarization...
Dendritic cells: On the move from bench to bedsideF O Nestle
Department of Dermatology, , , Switzerland
Nat Med 7:761-5. 2001..As dendritic cells increasingly become the adjuvant of choice in new approaches to cancer immunotherapy, a degree of protocol standardization is required to aid future large-scale clinical trials...
Distribution of carboxypeptidase M on lymphoid and myeloid cells parallels the other zinc-dependent proteases CD10 and CD13B de Saint-Vis
Laboratory for Immunological Research, Schering Plough, Dardilly, France
Blood 86:1098-105. 1995....
Interleukin 10 (IL-10) upregulates functional high affinity IL-2 receptors on normal and leukemic B lymphocytesA C Fluckiger
Laboratory for Immunological Research, Schering Plough, Dardilly, France
J Exp Med 178:1473-81. 1993..This effect of IL-10 may partly explain how T cells, which activate B cells in a CD40-dependent fashion, induce B cell proliferation and differentiation mostly through IL-2...
Follicular dendritic cells specifically express the long CR2/CD21 isoformY J Liu
Schering Plough, Laboratory for Immunological Research, Dardilly, France
J Exp Med 185:165-70. 1997..Thus, CD21L represents the first characterized human FDC-specific molecule, which may confer unique functions of FDCs in germinal center development...
Mature dendritic cells infiltrate the T cell-rich region of oral mucosa in chronic periodontitis: in situ, in vivo, and in vitro studiesR Jotwani
Department of Periodontics, School of Dental Medicine, State University of New York, Stony Brook, NY 11794, USA
J Immunol 167:4693-700. 2001..gingivalis, leading to release of counterregulatory cytokines and the formation of T cell-DC foci...
Identification and analysis of a novel member of the ubiquitin family expressed in dendritic cells and mature B cellsE E Bates
Schering Plough, Laboratory for Immunological Research, Dardilly, France
Eur J Immunol 27:2471-7. 1997..Comparative analysis and the expression pattern of this gene suggests a function in antigen processing and presentation...
The cytokine profile expressed by human dendritic cells is dependent on cell subtype and mode of activationB de Saint-Vis
Schering Plough, Laboratory for Immunological Research, Dardilly, France
J Immunol 160:1666-76. 1998..Thus, CD14+-derived DC expressing IL-10 and factor XIIIa seemed more closely related to germinal center dendritic cellsGCDC than to Langerhans cells...
A novel lysosome-associated membrane glycoprotein, DC-LAMP, induced upon DC maturation, is transiently expressed in MHC class II compartmentB de Saint-Vis
Schering Plough Laboratory for Immunological Research, Dardilly, France
Immunity 9:325-36. 1998..This suggests that DC-LAMP might change the lysosome function after the transfer of peptide-MHC class II molecules to the surface of DC...
CD40L activation of dendritic cells down-regulates DORA, a novel member of the immunoglobulin superfamilyE E Bates
Schering Plough, Laboratory for Immunological Research, Dardilly, France
Mol Immunol 35:513-24. 1998..This structure and expression suggests a function as a co-receptor, perhaps in an antigen uptake complex, or in homing or recirculation of DC...
The CD40 antigen and its ligandJ Banchereau
Schering Plough, Laboratory for Immunological Research, Dardilly, France
Annu Rev Immunol 12:881-922. 1994....
