S R Ash

Summary

Affiliation: Arnett Clinic
Country: USA

Publications

  1. ncbi Extracorporeal blood detoxification by sorbents in treatment of hepatic encephalopathy
    Stephen R Ash
    Dialysis Center for Greater Lafayette, West Lafayette, IN 47906, USA
    Adv Ren Replace Ther 9:3-18. 2002
  2. ncbi Peritoneal dialysis in acute renal failure of adults: the under-utilized modality
    S R Ash
    Greater Lafayette Health Systems, Arnett Clinic, HemoCleanse, Inc, Lafayette, Ind. 47904, USA
    Contrib Nephrol 144:239-54. 2004
  3. ncbi Laparoscopy for PD catheter placement: advantages and disadvantages versus peritoneoscopy
    Stephen Ash
    HemoCleanse, Inc, La Fayette, Indiana, USA
    Perit Dial Int 25:541-3. 2005
  4. ncbi Sorbent suspensions vs. sorbent columns for extracorporeal detoxification in hepatic failure
    Stephen R Ash
    HemoCleanse, Lafayette, IN, USA
    Ther Apher Dial 10:145-53. 2006
  5. ncbi The Allient dialysis system
    Stephen R Ash
    HemoCleanse Inc, 3601 Sagamore Parkway North, Lafayette, IN 47904, USA
    Semin Dial 17:164-6. 2004
  6. ncbi Chronic central venous catheters for dialysis and the Ash Split Cath catheter: rationale and clinical experience
    Stephen R Ash
    Dialysis Center for Greater Lafayette, Nephrology Department of Arnett Clinic, Ash Access Technology and HemoCleanse, Inc, Lafayette, Ind, USA
    Contrib Nephrol 142:128-52. 2004
  7. ncbi Chronic peritoneal dialysis catheters: overview of design, placement, and removal procedures
    Stephen R Ash
    Dialysis Center for Greater Lafayette, Arnett Clinic, and HemoCleanse, Inc, Lafayette, Indiana, 47904, USA
    Semin Dial 16:323-34. 2003
  8. ncbi Clinical trials of the T-fluted (Ash Advantage) peritoneal dialysis catheter
    Stephen R Ash
    Arnett Clinic Lafayette, IN, USA
    Adv Ren Replace Ther 9:133-43. 2002
  9. ncbi Chronic peritoneal dialysis catheters: challenges and design solutions
    S R Ash
    Arnett Clinic, Dialysis Center for Greater Lafayette, and Ash Access Inc, Lafayette, Indiana 47905, USA
    Int J Artif Organs 29:85-94. 2006
  10. ncbi Treatment of acetaminophen-induced hepatitis and fulminant hepatic failure with extracorporeal sorbent-based devices
    Stephen R Ash
    Greater Lafayette Health Services, West Lafayette, IN 47906, USA
    Adv Ren Replace Ther 9:42-53. 2002

Research Grants

  1. Pheresis Treatment of Bioterrorism-Induced Sepsis
    Stephen Ash; Fiscal Year: 2005
  2. MethLock vs. heparin as dialysis catheter lock
    Stephen Ash; Fiscal Year: 2007

Collaborators

Detail Information

Publications30

  1. ncbi Extracorporeal blood detoxification by sorbents in treatment of hepatic encephalopathy
    Stephen R Ash
    Dialysis Center for Greater Lafayette, West Lafayette, IN 47906, USA
    Adv Ren Replace Ther 9:3-18. 2002
    ....
  2. ncbi Peritoneal dialysis in acute renal failure of adults: the under-utilized modality
    S R Ash
    Greater Lafayette Health Systems, Arnett Clinic, HemoCleanse, Inc, Lafayette, Ind. 47904, USA
    Contrib Nephrol 144:239-54. 2004
  3. ncbi Laparoscopy for PD catheter placement: advantages and disadvantages versus peritoneoscopy
    Stephen Ash
    HemoCleanse, Inc, La Fayette, Indiana, USA
    Perit Dial Int 25:541-3. 2005
  4. ncbi Sorbent suspensions vs. sorbent columns for extracorporeal detoxification in hepatic failure
    Stephen R Ash
    HemoCleanse, Lafayette, IN, USA
    Ther Apher Dial 10:145-53. 2006
    ....
  5. ncbi The Allient dialysis system
    Stephen R Ash
    HemoCleanse Inc, 3601 Sagamore Parkway North, Lafayette, IN 47904, USA
    Semin Dial 17:164-6. 2004
    ..The Allient should make dialysis in the ICU or home setting much more practical, reducing training requirements and increasing safety...
  6. ncbi Chronic central venous catheters for dialysis and the Ash Split Cath catheter: rationale and clinical experience
    Stephen R Ash
    Dialysis Center for Greater Lafayette, Nephrology Department of Arnett Clinic, Ash Access Technology and HemoCleanse, Inc, Lafayette, Ind, USA
    Contrib Nephrol 142:128-52. 2004
  7. ncbi Chronic peritoneal dialysis catheters: overview of design, placement, and removal procedures
    Stephen R Ash
    Dialysis Center for Greater Lafayette, Arnett Clinic, and HemoCleanse, Inc, Lafayette, Indiana, 47904, USA
    Semin Dial 16:323-34. 2003
    ..Nephrologists should make the critical decisions regarding the choice of access devices and methods for placement as they do for the choice to remove such access devices...
  8. ncbi Clinical trials of the T-fluted (Ash Advantage) peritoneal dialysis catheter
    Stephen R Ash
    Arnett Clinic Lafayette, IN, USA
    Adv Ren Replace Ther 9:133-43. 2002
    ..Multiple fluted ports appear to diminish omental attachment. The catheter may be a useful alternative to conventional Tenckhoff catheters in patients at high risk of catheter failure or in standard peritoneal dialysis patients...
  9. ncbi Chronic peritoneal dialysis catheters: challenges and design solutions
    S R Ash
    Arnett Clinic, Dialysis Center for Greater Lafayette, and Ash Access Inc, Lafayette, Indiana 47905, USA
    Int J Artif Organs 29:85-94. 2006
    ..Improvements in catheter design may expand the use of peritoneal dialysis as a successful home dialysis therapy...
  10. ncbi Treatment of acetaminophen-induced hepatitis and fulminant hepatic failure with extracorporeal sorbent-based devices
    Stephen R Ash
    Greater Lafayette Health Services, West Lafayette, IN 47906, USA
    Adv Ren Replace Ther 9:42-53. 2002
    ....
  11. ncbi Treatment of severe tricyclic antidepressant overdose with extracorporeal sorbent detoxification
    Stephen R Ash
    Arnett Clinic, Greater Lafayette Health Services, West Lafayette, IN 47906, USA
    Adv Ren Replace Ther 9:31-41. 2002
    ..None of the patients died despite their high risk for ventricular arrhythmias, seizures, and death. Clinical improvement may have been attributable to removal of free drug from the blood or to removal of drug metabolites...
  12. ncbi The evolution and function of central venous catheters for dialysis
    S R Ash
    Nephrology Department, Arnett Clinic and Dialysis Centers for Greater Lafayette, Lafayette, Purdue University, Indiana, USA
    Semin Dial 14:416-24. 2001
    ..CVC for dialysis will remain a necessary choice for many patients beginning and continuing dialysis therapy...
  13. ncbi Treatment of systemic inflammatory response syndrome by push-pull powdered sorbent pheresis: a Phase 1 clinical trial
    S R Ash
    HemoCleanse, Inc, West Lafayette, Indiana 47906 1349, USA
    Ther Apher 5:497-505. 2001
    ..The selected patients tolerated treatment by the DTPF system well, but proof of benefit of the device remains to be proven in a Phase 2 clinical trial with randomized controls...
  14. ncbi Powdered sorbent liver dialysis and pheresis in treatment of hepatic failure
    S R Ash
    Dialysis Center of Lafayette, West Lafayette, Indiana, USA
    Ther Apher 5:404-16. 2001
    ....
  15. ncbi Push-pull sorbent-based pheresis and hemodiabsorption in the treatment of hepatic failure: preliminary results of a clinical trial with the BioLogic-DTPF System
    S R Ash
    Purdue University, Department of Comparative Medicine, West Lafayette, Indiana, USA
    Ther Apher 4:218-28. 2000
    ....
  16. ncbi Fluid mechanics and clinical success of central venous catheters for dialysis--answers to simple but persisting problems
    Stephen R Ash
    Department of Nephrology, Arnett Clinic, WellBound, Inc, Ash Access Technology, HemoCleanse, Inc, Lafayette, Indiana, USA
    Semin Dial 20:237-56. 2007
    ..With a few more improvements, chronic CVC for dialysis could become a painless, effective and safe long-term access for the majority of dialysis patients and acceptable as an alternative to AV grafts...
  17. ncbi Cytokines and endotoxin removal by sorbents and its application in push-pull sorbent-based pheresis: the BioLogic-DTPF System
    J Steczko
    HemoCleanse, Inc, West Lafayette, IN 47906, USA
    Artif Organs 23:310-8. 1999
    ..6-23.4 ml/min, bilirubin at 17.8-34.7 ml/min, and creatinine at 53.6-82.6 ml/min. The removal of some cytokines during the first clinical trial is also discussed...
  18. ncbi Push-pull sorbent-based pheresis treatment in an experimental canine endotoxemia model: preliminary report
    A T Peter
    Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, IN 47907 1248, USA
    Int J Artif Organs 22:177-88. 1999
    ..A more realistic canine sepsis model with mortality after several days (the Escherichia coli- infected intraperitoneal clot) will also be considered in future studies...
  19. ncbi Effect of hemodiabsorption and sorbent-based pheresis on amino acid levels in hepatic failure
    J Steczko
    HemoCleanse, Inc, West Lafayette, Indiana, 47906, USA
    Int J Artif Organs 23:375-88. 2000
    ..The addition of the PF module improves the removal of bilirubin and similarly protein-bound chemicals. Changes in amino acid profiles by the Unit and the PF-Unit contrast markedly with other extracorporeal devices...
  20. ncbi Sorbent suspension reactor for extracorporeal detoxification in hepatic failure or drug overdose
    Stephen R Ash
    Greater Lafayette Health Services, West Lafayette, IN, USA
    ASAIO J 50:lviii-lxv. 2004
  21. ncbi Advances in tunneled central venous catheters for dialysis: design and performance
    Stephen R Ash
    Clarian Arnett Health and Wellbound, Inc, West Lafayette, Indiana, USA
    Semin Dial 21:504-15. 2008
    ..Current challenges and future directions for tunneled CVC for dialysis are discussed, included means to diminish catheter-related infections, catheter tip clotting, fibrous sheathing, central venous stenosis, and external component bulk...
  22. ncbi Sorbents in treatment of uremia: a short history and a great future
    Stephen R Ash
    Clarian Arnett Health and Wellbound, Inc, Lafayette, Indiana, USA
    Semin Dial 22:615-22. 2009
    ..It also describes a number of improvements made in dialysis machines using sorbent regeneration of the dialysate. Some ongoing improvements in sorbent chemistry are also described...
  23. ncbi Chronic peritoneal dialysis catheters: procedures for placement, maintenance, and removal
    Stephen R Ash
    HemoCleanse, Inc. and Purdue University, West Lafayette, IN 47906, USA
    Semin Nephrol 22:221-36. 2002
    ....
  24. ncbi Microbial inactivation properties of a new antimicrobial/antithrombotic catheter lock solution (citrate/methylene blue/parabens)
    Janusz Steczko
    R and D, Ash Access Technology, Inc, Lafayette, IN, USA
    Nephrol Dial Transplant 24:1937-45. 2009
    ..These effects were compared to the antimicrobial properties of heparin at 2500 units/ml...
  25. ncbi Catheter related bacteremia in rats: A preliminary report on the effect of methylene blue coated catheter
    Augustine T Peter
    Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA
    Indian J Exp Biol 44:183-8. 2006
    ..Based on the results it can be concluded that for this type of gross contamination, catheter coating alone may not eliminate infection/bacteremia...
  26. ncbi Use of continuous-flow peritoneal dialysis for the treatment of acute renal failure in an adult horse
    Laurie L Gallatin
    Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA
    J Am Vet Med Assoc 226:756-9, 732. 2005
    ..In adult horses, it appears that CFPD can be used to successfully treat acute renal failure that is refractory to conventional treatments...
  27. ncbi Sorbent-based artificial liver devices: principles of operation, chemical effects and clinical results
    Benoît Carpentier
    Universite de Technologie de Compiegne, Biomechanics and Biomedical Engineering, Compiegne, France
    Expert Rev Med Devices 4:839-61. 2007
    ..Further randomized outcome studies are necessary to prove clinical outcome benefit of the artificial liver support devices, and define what types of patients appear most amenable to therapy...
  28. ncbi Prediction of hemodialysis sorbent cartridge urea nitrogen capacity and sodium release from in vitro tests
    Benjamin P Rosenbaum
    Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Hemodial Int 12:244-53. 2008
    ..786. These mathematical models should allow for prediction of patient sodium profiles and the time of column urea saturation based on simple inputs relating to patient chemistries and the dialysis treatment...
  29. ncbi Ash Split Catheter for vascular access in apheresis
    Stephen R Ash
    Ther Apher Dial 7:150-2. 2003
  30. ncbi Predicting dialysate sodium composition in sorbent dialysis using single point and multiple-dilution conductivity measurement
    Benjamin P Rosenbaum
    Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    ASAIO J 51:754-60. 2005
    ....

Research Grants3

  1. Pheresis Treatment of Bioterrorism-Induced Sepsis
    Stephen Ash; Fiscal Year: 2005
    ..The safety systems of the existing PF system will be modified to meet the needs of the stand-alone system. Finally, an animal model of sepsis will be used to check efficacy and safety of the entire system. ..
  2. MethLock vs. heparin as dialysis catheter lock
    Stephen Ash; Fiscal Year: 2007
    ..In Phase II we will implement the protocol in a number of dialysis centers and complete the study as originally proposed or as modified after Phase I. ..