Research Topics
| David L HytenSummaryAffiliation: Agricultural Research Service Country: USA Publications
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Detail Information
Publications
High-throughput SNP discovery through deep resequencing of a reduced representation library to anchor and orient scaffolds in the soybean whole genome sequenceDavid L Hyten
Soybean Genomics and Improvement Laboratory, US Department of Agriculture, Agricultural Research Service, Beltsville, MD 20705, USA
BMC Genomics 11:38. 2010....
High-throughput genotyping with the GoldenGate assay in the complex genome of soybeanDavid L Hyten
Soybean Genomics and Improvement Laboratory, US Department of Agriculture, Agricultural Research Service, Beltsville, MD 20705, USA
Theor Appl Genet 116:945-52. 2008..The high success rate of the GoldenGate assay makes this a useful technique for quickly creating high density genetic maps in species where SNP markers are rapidly becoming available...
High-throughput SNP discovery and assay development in common beanDavid L Hyten
Soybean Genomics and Improvement Laboratory, US Department of Agriculture, Agricultural Research Service, Beltsville, Maryland 20705, USA
BMC Genomics 11:475. 2010..To this end we developed a method which couples sequences obtained from the Roche 454-FLX system (454) with the Illumina Genome Analyzer (GA) for high-throughput SNP discovery...
Highly variable patterns of linkage disequilibrium in multiple soybean populationsDavid L Hyten
Soybean Genomics and Improvement Laboratory, U S Department of Agriculture, Agricultural Research Service, Beltsville, Maryland 20705, USA
Genetics 175:1937-44. 2007..G. soja appears to be ideal for fine mapping of genes, but due to the highly variable levels of LD in the Landraces and the Elite Cultivars, whole-genome association analysis in soybean may be more difficult than first anticipated...
A soybean transcript map: gene distribution, haplotype and single-nucleotide polymorphism analysisIk Young Choi
Soybean Genomics and Improvement Laboratory, USDA, ARS, Beltsville, Maryland 20705, USA
Genetics 176:685-96. 2007....
SNP-PHAGE--High throughput SNP discovery pipelineLakshmi K Matukumalli
US Department of Agriculture, ARS, Beltsville Agricultural Research Center, Bovine Functional Genomics Laboratory, Beltsville, MD 20705, USA
BMC Bioinformatics 7:468. 2006..Although these tasks are routinely performed by several groups, an integrated open source SNP discovery pipeline that can be easily adapted by new groups interested in SNP marker development is currently unavailable...
Impacts of genetic bottlenecks on soybean genome diversityDavid L Hyten
Soybean Genomics and Improvement Laboratory, U.S. Department of Agriculture, Agricultural Research Service, Beltsville, MD 20705, USA
Proc Natl Acad Sci U S A 103:16666-71. 2006....
Application of machine learning in SNP discoveryLakshmi K Matukumalli
Beltsville Agricultural Research Center, Bovine Functional Genomics Laboratory, US Department of Agriculture, ARS, Beltsville, MD 20705, USA
BMC Bioinformatics 7:4. 2006..ML methods have also been successfully applied to other bioinformatics problems in predicting genes, promoters, transcription factor binding sites and protein structures...
