Farhan A Syed

Summary

Affiliation: Abbott Laboratories
Country: USA

Publications

  1. ncbi The pathophysiology of the aging skeleton
    Farhan A Syed
    Abbott Bioresearch Center, Worcester, MA 01545, USA
    Curr Osteoporos Rep 8:235-40. 2010
  2. ncbi Clinical, cellular and molecular phenotypes of aging bone
    Farhan A Syed
    College of Medicine, Mayo Clinic, Rochester, Minn, USA
    Interdiscip Top Gerontol 37:175-92. 2010
  3. ncbi Rodent models of aging bone: an update
    Farhan A Syed
    Abbott Bioresearch Center, Worcester, MA 01545, USA
    Curr Osteoporos Rep 9:219-28. 2011
  4. ncbi Distinct effects of loss of classical estrogen receptor signaling versus complete deletion of estrogen receptor alpha on bone
    Farhan A Syed
    Endocrine Research Unit, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Bone 49:208-16. 2011
  5. ncbi Effects of loss of classical estrogen response element signaling on bone in male mice
    Farhan A Syed
    Endocrine Research Unit, Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, Minnesota 55905, USA
    Endocrinology 148:1902-10. 2007
  6. ncbi Loss of ERE binding activity by estrogen receptor-alpha alters basal and estrogen-stimulated bone-related gene expression by osteoblastic cells
    Volha Rudnik
    Endocrine Research Unit, Rochester, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    J Cell Biochem 103:896-907. 2008
  7. ncbi Effects of chronic estrogen treatment on modulating age-related bone loss in female mice
    Farhan A Syed
    Endocrine Research Unit, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    J Bone Miner Res 25:2438-46. 2010
  8. ncbi Skeletal effects of estrogen are mediated by opposing actions of classical and nonclassical estrogen receptor pathways
    Farhan A Syed
    Endocrine Research Unit, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Bone Miner Res 20:1992-2001. 2005
  9. ncbi Integrative physiology of the aging bone: insights from animal and cellular models
    Farhan A Syed
    Abbott Bioresearch Center, Worcester, Massachusetts, USA
    Ann N Y Acad Sci 1211:95-106. 2010
  10. ncbi Age-dependent renal cortical microvascular loss in female mice
    Victor H Urbieta-Caceres
    Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, USA
    Am J Physiol Endocrinol Metab 302:E979-86. 2012

Collaborators

Detail Information

Publications10

  1. ncbi The pathophysiology of the aging skeleton
    Farhan A Syed
    Abbott Bioresearch Center, Worcester, MA 01545, USA
    Curr Osteoporos Rep 8:235-40. 2010
    ..It also briefly outlines recent studies on the relationship between bone and fat in the marrow as well as the periphery...
  2. ncbi Clinical, cellular and molecular phenotypes of aging bone
    Farhan A Syed
    College of Medicine, Mayo Clinic, Rochester, Minn, USA
    Interdiscip Top Gerontol 37:175-92. 2010
    ....
  3. ncbi Rodent models of aging bone: an update
    Farhan A Syed
    Abbott Bioresearch Center, Worcester, MA 01545, USA
    Curr Osteoporos Rep 9:219-28. 2011
    ..Impactful information regarding aging and the bone may then allow the application of better pharmacologic as well as nonpharmacologic regimens to alleviate bone loss due to aging...
  4. ncbi Distinct effects of loss of classical estrogen receptor signaling versus complete deletion of estrogen receptor alpha on bone
    Farhan A Syed
    Endocrine Research Unit, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Bone 49:208-16. 2011
    ..Further studies defining these pathways may lead to novel approaches to selectively modulate ER signaling for beneficial skeletal effects...
  5. ncbi Effects of loss of classical estrogen response element signaling on bone in male mice
    Farhan A Syed
    Endocrine Research Unit, Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, Minnesota 55905, USA
    Endocrinology 148:1902-10. 2007
    ..Collectively, these data demonstrate that classical ERalpha signaling is crucial for the development of the murine male skeleton...
  6. ncbi Loss of ERE binding activity by estrogen receptor-alpha alters basal and estrogen-stimulated bone-related gene expression by osteoblastic cells
    Volha Rudnik
    Endocrine Research Unit, Rochester, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    J Cell Biochem 103:896-907. 2008
    ..Collectively, these findings indicate that ERE signaling plays a significant role in mediating effects of estrogen on osteoblastic differentiation markers and on IGF-I mRNA levels...
  7. ncbi Effects of chronic estrogen treatment on modulating age-related bone loss in female mice
    Farhan A Syed
    Endocrine Research Unit, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA
    J Bone Miner Res 25:2438-46. 2010
    ..The observed increase in osteoblastic differentiation and proliferation marker gene expression in progenitor bone marrow cells from aged versus young mice may represent a compensatory mechanism in response to ongoing bone loss...
  8. ncbi Skeletal effects of estrogen are mediated by opposing actions of classical and nonclassical estrogen receptor pathways
    Farhan A Syed
    Endocrine Research Unit, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Bone Miner Res 20:1992-2001. 2005
    ..This study defines the skeletal phenotype and responses to ovariectomy and estrogen replacement in these mice...
  9. ncbi Integrative physiology of the aging bone: insights from animal and cellular models
    Farhan A Syed
    Abbott Bioresearch Center, Worcester, Massachusetts, USA
    Ann N Y Acad Sci 1211:95-106. 2010
    ....
  10. ncbi Age-dependent renal cortical microvascular loss in female mice
    Victor H Urbieta-Caceres
    Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, USA
    Am J Physiol Endocrinol Metab 302:E979-86. 2012
    ..However, estrogen may play a role in protecting the kidney by decreasing oxidative stress and attenuating mechanisms linked to renal interstitial fibrosis...