Feng Luo

Summary

Affiliation: Abbott Laboratories
Country: USA

Publications

  1. ncbi Attenuation of brain response to heroin correlates with the reinstatement of heroin-seeking in rats by fMRI
    Feng Luo
    Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Neuroimage 22:1328-35. 2004
  2. ncbi Magnetic resonance imaging detection and time course of cerebral microhemorrhages during passive immunotherapy in living amyloid precursor protein transgenic mice
    Feng Luo
    Translational Imaging and Biochemical Biomarkers, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, Illinois 60064, USA
    J Pharmacol Exp Ther 335:580-8. 2010
  3. ncbi Confounding effects of volatile anesthesia on CBV assessment in rodent forebrain following ethanol challenge
    Feng Luo
    Experimental Imaging Abbott Laboratories, Abbott Park, Illinois 60064, USA
    J Magn Reson Imaging 26:557-63. 2007
  4. ncbi Differential responses in CBF and CBV to cocaine as measured by fMRI: implications for pharmacological MRI signals derived oxygen metabolism assessment
    Feng Luo
    Experimental Imaging, Abbott Laboratories, Abbott Park, USA
    J Psychiatr Res 43:1018-24. 2009
  5. ncbi Default-mode-like network activation in awake rodents
    Jaymin Upadhyay
    Translational Sciences, Advanced Technology, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, Illinois, United States of America
    PLoS ONE 6:e27839. 2011
  6. ncbi Characterization of 7- and 19-month-old Tg2576 mice using multimodal in vivo imaging: limitations as a translatable model of Alzheimer's disease
    Feng Luo
    Experimental Imaging Advanced Technology, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL 60064, USA
    Neurobiol Aging 33:933-44. 2012
  7. ncbi Paradigm shift in translational neuroimaging of CNS disorders
    Unal Sakoglu
    Translational Imaging Advanced Technology, Global Pharmaceutical Research and Development, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, IL 60064, USA
    Biochem Pharmacol 81:1374-87. 2011
  8. ncbi Translational neuroimaging of the CNS: novel pathways to drug development
    Gerard B Fox
    Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL 60064
    Mol Interv 9:302-13. 2009
  9. ncbi Hemodynamic and metabolic changes induced by cocaine in anesthetized rat observed with multimodal functional MRI
    Karl F Schmidt
    Center for Comparative NeuroImaging, University of Massachusetts, Worcester, MA, USA
    Psychopharmacology (Berl) 185:479-86. 2006
  10. ncbi The recovery cycle of bat duration-selective collicular neurons varies with hunting phase
    Xin Wang
    College of Life Sciences, Central China Normal University, Wuhan, People s Republic of China
    Neuroreport 19:861-5. 2008

Collaborators

Detail Information

Publications15

  1. ncbi Attenuation of brain response to heroin correlates with the reinstatement of heroin-seeking in rats by fMRI
    Feng Luo
    Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Neuroimage 22:1328-35. 2004
    ....
  2. ncbi Magnetic resonance imaging detection and time course of cerebral microhemorrhages during passive immunotherapy in living amyloid precursor protein transgenic mice
    Feng Luo
    Translational Imaging and Biochemical Biomarkers, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, Illinois 60064, USA
    J Pharmacol Exp Ther 335:580-8. 2010
    ..A highly selective antibody for soluble A? is needed to address the question of whether antibodies that do not bind to deposited A? have microhemorrhage liability...
  3. ncbi Confounding effects of volatile anesthesia on CBV assessment in rodent forebrain following ethanol challenge
    Feng Luo
    Experimental Imaging Abbott Laboratories, Abbott Park, Illinois 60064, USA
    J Magn Reson Imaging 26:557-63. 2007
    ..To compare and contrast the pattern and characteristics of the cerebral blood volume (CBV) response to ethanol (EtOH) in rats under awake and anesthetized conditions...
  4. ncbi Differential responses in CBF and CBV to cocaine as measured by fMRI: implications for pharmacological MRI signals derived oxygen metabolism assessment
    Feng Luo
    Experimental Imaging, Abbott Laboratories, Abbott Park, USA
    J Psychiatr Res 43:1018-24. 2009
    ..The initial transient state and later steady state CBF and CBV responses to a hypercapnic challenge were measured...
  5. ncbi Default-mode-like network activation in awake rodents
    Jaymin Upadhyay
    Translational Sciences, Advanced Technology, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, Illinois, United States of America
    PLoS ONE 6:e27839. 2011
    ..This investigation demonstrates that the cingulate is an important component of both the rodent DMN-like and anxiety networks...
  6. ncbi Characterization of 7- and 19-month-old Tg2576 mice using multimodal in vivo imaging: limitations as a translatable model of Alzheimer's disease
    Feng Luo
    Experimental Imaging Advanced Technology, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL 60064, USA
    Neurobiol Aging 33:933-44. 2012
    ..Our data are discussed in the context of disease biomarker identification and target validation, suggesting little or no utility for translational based studies using Tg2576 mice...
  7. ncbi Paradigm shift in translational neuroimaging of CNS disorders
    Unal Sakoglu
    Translational Imaging Advanced Technology, Global Pharmaceutical Research and Development, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, IL 60064, USA
    Biochem Pharmacol 81:1374-87. 2011
    ..In this paper, we review recent developments in structural and functional MRI and their use to probe functional connectivity in various CNS disorders such as schizophrenia, mood disorders, Alzheimer's disease (AD) and pain...
  8. ncbi Translational neuroimaging of the CNS: novel pathways to drug development
    Gerard B Fox
    Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL 60064
    Mol Interv 9:302-13. 2009
    ..In this brief review, we highlight examples of the new wave of neuroimaging studies that engender useful biomarkers of disease for translational research...
  9. ncbi Hemodynamic and metabolic changes induced by cocaine in anesthetized rat observed with multimodal functional MRI
    Karl F Schmidt
    Center for Comparative NeuroImaging, University of Massachusetts, Worcester, MA, USA
    Psychopharmacology (Berl) 185:479-86. 2006
    ....
  10. ncbi The recovery cycle of bat duration-selective collicular neurons varies with hunting phase
    Xin Wang
    College of Life Sciences, Central China Normal University, Wuhan, People s Republic of China
    Neuroreport 19:861-5. 2008
    ..These data indicate that different groups of duration-selective neurons underlie the bat's ability to effectively perform echo recognition and ranging during different phases of hunting...
  11. ncbi Duration-sensitive neurons in the inferior colliculus of horseshoe bats: adaptations for using CF-FM echolocation pulses
    Feng Luo
    College of Life Sciences, Central China Normal University, Wuhan, 430079, China
    J Neurophysiol 99:284-96. 2008
    ..Therefore presentation of a CF-FM stimulus improved the duration sensitivity in IC neurons by increasing the ratio of duration-tuned neurons and making them less susceptible to changes in signal intensity...
  12. ncbi Spatial correlations of laminar BOLD and CBV responses to rat whisker stimulation with neuronal activity localized by Fos expression
    Hanbing Lu
    Department of Biophysics, Medical College of Wisconsin, Milwaukee 53226, USA
    Magn Reson Med 52:1060-8. 2004
    ..We conclude that neuronal activity can be inferred from CBV fMRI data with high spatial accuracy. The data indicate that both intracolumn functional connectivity and neurovascular coupling can be studied using CBV fMRI...
  13. ncbi Characterization of effects of mean arterial blood pressure induced by cocaine and cocaine methiodide on BOLD signals in rat brain
    Feng Luo
    Biophysics Research Institute, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Magn Reson Med 49:264-70. 2003
    ..These results confirm that the BOLD-weighted fMRI method can be extended to map drug-induced neuronal activity...
  14. ncbi Transient relationships among BOLD, CBV, and CBF changes in rat brain as detected by functional MRI
    Gaohong Wu
    Biophysics Research Institute, Medical College of Wisconsin, Milwaukee, Wisconsin 53226-0509, USA
    Magn Reson Med 48:987-93. 2002
    ..To avoid overestimation of the cerebral metabolic rate of oxygen changes seen using fMRI, caution should be taken to not include voxels with large veins and a large BOLD signal...
  15. ncbi Multiecho segmented EPI with z-shimmed background gradient compensation (MESBAC) pulse sequence for fMRI
    Zhu Li
    Biophysics Research Institute, Medical College of Wisconsin, Milwaukee 53226, USA
    Magn Reson Med 48:312-21. 2002
    ..The MESBAC sequence will be particularly useful for pharmacological and affective fMRI studies in brain regions such as the OFC, nucleus accumbens, amygdala, parahippocampus, etc...