Lui G Forni

..However, mortality is still approximately 50% for those requiring admission to intensive care unit. Furthermore, there is a high morbidity associated with both the diseases themselves and the treatment...

..Finally, it is important not to forget to read the latest surviving sepsis guidelines...

..Finally, a large retrospective cohort study comparing outcomes of patients treated with continuous venovenous haemofiltration or intermittent haemodialysis is outlined...

..Finally, we discuss another good reason to take statins...

..Finally, a large multicentred trial comparing continuous venovenous haemofiltration with intermittent haemodialysis is outlined, the results of which pose more questions than answers...

..Particular attention is paid to the more fulminant presentations of these conditions and the role of the critical care physician in their diagnosis and management...

..Another study highlights the increasing burden of end-stage renal disease on intensive care unit resources with some interesting results. And there is more on citrate, the new anticoagulant!..

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..We describe here the various attempts in the literature that have been made to address this observation and highlight recent studies that reveal potential sources of such hitherto unmeasured anions...

..We describe some recent studies focusing on these issues with the hope that they may lead to better treatment for our patients...

..Troponin raises its head again and we are still left quizzing over its value in the ICU. Finally we discuss a paper on the outcome of the obese patient on a general ICU. Like sepsis a continuing challenge...

..We also review some new studies on biomarkers in the diagnosis of acute kidney injury as well as add yet another nail in the coffin for loop diuretics in the therapy of acute kidney injury...

..We also take a look at infections in the ICU with particular regard to a recent study which examined isolating patients with methicillin-resistant Staphylococcus aureus (MRSA)...

..Saline or albumen for resuscitation? The answer became clearer in May, as did what to do about all those mobile phones.....

..The fragmentation pattern observed in negative ion mass spectrometry in the majority of the volume expanded patients may represent the presence of an isomer of the sodium pump inhibitor previously described in placental material...

..The contribution of these anions to generating an acidosis, and thus potentially limiting the extent of exercise, has never been acknowledged...

..Using the LC/ESI-MS method described, a unique plasma ultrafiltrate anion profile was obtained for each of the groups studied that provides rapid diagnosis of the type of underlying acidosis...