Michael Stratton

Summary

Affiliation: Wellcome Trust Genome Campus
Country: UK

Publications

  1. ncbi Genome resequencing and genetic variation
    Michael Stratton
    Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK
    Nat Biotechnol 26:65-6. 2008
  2. ncbi Somatic structural rearrangements in genetically engineered mouse mammary tumors
    Ignacio Varela
    Wellcome Trust Sanger Institute, Hinxton, Cambridge CB101SA, UK
    Genome Biol 11:R100. 2010
  3. ncbi RNA editing of human microRNAs
    Matthew J Blow
    Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
    Genome Biol 7:R27. 2006
  4. ncbi Mutation analysis of 24 known cancer genes in the NCI-60 cell line set
    Ogechi N Ikediobi
    Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom
    Mol Cancer Ther 5:2606-12. 2006
  5. ncbi The cancer genome
    Michael R Stratton
    Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK
    Nature 458:719-24. 2009
  6. ncbi Exploring the genomes of cancer cells: progress and promise
    Michael R Stratton
    Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK
    Science 331:1553-8. 2011

Collaborators

  • P Andrew Futreal
  • Richard Wooster
  • Stijn van Dongen
  • Anton J Enright
  • David Richardson
  • Peter J Campbell
  • Thomas Santarius
  • John N Weinstein
  • David Jones
  • Tara L Naylor
  • Markus Ringnér
  • Ignacio Varela
  • Ogechi N Ikediobi
  • Ed Dicks
  • Matthew J Blow
  • David J Adams
  • Eva Schut
  • Christiaan Klijn
  • Lodewyk Fa Wessels
  • Lucy Stebbings
  • Laura J Mudie
  • Danushka Galappaththige
  • Jos Jonkers
  • Hanneke van der Gulden
  • Phillip J Stephens
  • Sjoerd Klarenbeek
  • Vivienne Kosmidou
  • William Reinhold
  • Jennifer Varian
  • Tim Avis
  • Richard Lugg
  • Jennifer Cole
  • Tony Webb
  • Janet Perry
  • Philip Stephens
  • Keiran Raine
  • Tatiana Mironenko
  • Gemma Buck
  • Rachel Harrison
  • Raffaella Smith
  • Andrew Menzies
  • Lisa Brackenbury
  • Adrian Parker
  • Jonathan Hinton
  • Chris Hunter
  • Simon Forbes
  • Russell J Grocock
  • Graham Bignell
  • Syd Barthorpe
  • Sofie West
  • Andy Jenkinson
  • Helen Davies
  • Calli Tofts
  • Sarah Edkins
  • Kristian Gray
  • Alex Small
  • Sara Widaa
  • Katy Hills
  • Sarah O'Meara
  • Kelly Halliday
  • Jon Teague
  • Andy Yates
  • Jody Clements
  • Rebecca Shepherd
  • Adam Butler
  • Claire Stevens
  • Helen Solomon

Detail Information

Publications7

  1. ncbi Genome resequencing and genetic variation
    Michael Stratton
    Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK
    Nat Biotechnol 26:65-6. 2008
  2. ncbi Somatic structural rearrangements in genetically engineered mouse mammary tumors
    Ignacio Varela
    Wellcome Trust Sanger Institute, Hinxton, Cambridge CB101SA, UK
    Genome Biol 11:R100. 2010
    ..These were models of Trp53-mutated breast cancer, Brca1- and Brca2-associated hereditary breast cancer, and E-cadherin (Cdh1) mutated lobular breast cancer...
  3. ncbi RNA editing of human microRNAs
    Matthew J Blow
    Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
    Genome Biol 7:R27. 2006
    ..These miRNAs may have been annotated to the wrong genomic strand. CONCLUSION: Our results indicate that RNA editing increases the diversity of miRNAs and their targets, and hence may modulate miRNA function...
  4. ncbi Mutation analysis of 24 known cancer genes in the NCI-60 cell line set
    Ogechi N Ikediobi
    Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, United Kingdom
    Mol Cancer Ther 5:2606-12. 2006
    ....
  5. ncbi The cancer genome
    Michael R Stratton
    Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK
    Nature 458:719-24. 2009
    ..These studies will provide us with a detailed and comprehensive perspective on how individual cancers have developed...
  6. ncbi Exploring the genomes of cancer cells: progress and promise
    Michael R Stratton
    Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK
    Science 331:1553-8. 2011
    ..Here, I provide an overview of what these efforts have revealed to date about the origin and behavioral features of cancer cells and how this genomic information is being exploited to improve diagnosis and therapy of the disease...